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The map label for this gene is ntrY [H]

Identifier: 167625342

GI number: 167625342

Start: 4178193

End: 4179563

Strand: Reverse

Name: ntrY [H]

Synonym: Shal_3431

Alternate gene names: 167625342

Gene position: 4179563-4178193 (Counterclockwise)

Preceding gene: 167625343

Following gene: 167625339

Centisome position: 79.96

GC content: 46.32

Gene sequence:

>1371_bases
ATGAGCCAGATTAGTCATATTTCATTAAGAGTCAAACTGATCGCTAGCTGCGTATCGTCGGTGGCCATGGGGTTGTTACT
GGCTTTCGCATTACAGCTTTGGCTCGCAAGAACCGCCGTAATAACTAAGGCGTTTTTTGAGCCGCAGTCGCTCTATCTGG
TGATCTTTATCTGCTGCTTACTGCTGGTGGCATGGTTAAGTTTCTTGGCGACTAGGCGTTTAGATACCAGCTTGCAGGCA
CTCGAGCTTGGGCTACTTAACTTTAAGGATAACGATTTTAGCGTCAGTATTCCTGTCTCGGGGAACGGTCAGCTTAGGGC
GCTAGCCGAACTCTTTAATGAGTCTGCGCAAACATTGCGCAAAGAGCGGCAATACATTTACCAGCGCGAATTGCTGCTCG
ATAAAGTCATTCAAAGCTCCCCTAACGTGATGCTGCTACTCGATGATGAACAGCGGATCATCTATGCCAATGATGCGGCG
AGGCATCTGTTTAATAACGGCTTGCGTATCGAAGGAATGAGCTTAGAAAAGCTGTTACAAGAAGTTCCTCAAGAGCTGGT
CAGCGCGCTGAATAACCCCAAAGATGGGCTGTTTTCACTGAGTAATGACGCTGATAACAGTGATATTGAGACCTGGCACC
TGTCTCGTGGACAGTTTTTGCTGAACGGACAATTTCATCATTTAGTGCTCTTAAAACAGATGACCCGAGAGCTCAATCGC
CAAGAAGTGGCGGTATGGAAGAAGGTGATCCGCATCATCAGTCATGAACTGAATAACTCGGTTGCGCCAATAGCTTCTAT
GGTCAACTCAGGACGAGTGATTACCAAAGAGCTCAACGACCCAAAACTGAAGCTTATCTTCGATACCATCGAAGATAGAA
GCAGTCATCTGAGCCAGTTTATCTTCAACTATGCTCGTTTTGCTAAATTGCCATTACCGAACAAGACCTGCGTCGATTGG
CAAACCTTAACTGAGCAGCTTAAACAGCACTATCAGTTTGAACTACTTGGTGAGTTTCCGCAAAGACCCGTTAGTTTTGA
CGTGATTCAGATGGAGCAGGTGCTGCTAAACCTGCTTAAAAACGCCCATGAGTCTGGCTCTGATCTCGATAGAATTAGCC
TAGAGATCAGAGAGTCGAGCTTGTCAGATCCCACTCAAGGGTTATGCATCGAAGTTAAGGATGCAGGCGTTGGGATGTCA
GCCGATGTATTAAGTCAAGCGCTACTGCCTTTTTACTCAACCAAGCAGTCGGGTACCGGCTTAGGCTTACCTTTATGCCG
AGAGATAATAGAAGCTCATGATGGACGAATTAGTTTACATAATCGCGATGAAAAAGGTCTGTGTGTGAGCCTTTGGTTAC
CTAGCACTTAG

Upstream 100 bases:

>100_bases
GCTTAAGCAGGCAGGCCTTGTATCGGCGCATGGATAAGTATGGGATTGATAAATAGCTTTATTTCAAGCTTTCTCTTTAA
CTTTCGGCAAGAGTGCCCCT

Downstream 100 bases:

>100_bases
GGCTGTATGGTTGCTGTAATATGAGCTGTTTACTGAGTGGTAAATTGAGCAATAAGCTGAGCGGTAAAGAGTGAACTGTA
GAGAAAGTGTTGTACTGTTC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MSQISHISLRVKLIASCVSSVAMGLLLAFALQLWLARTAVITKAFFEPQSLYLVIFICCLLLVAWLSFLATRRLDTSLQA
LELGLLNFKDNDFSVSIPVSGNGQLRALAELFNESAQTLRKERQYIYQRELLLDKVIQSSPNVMLLLDDEQRIIYANDAA
RHLFNNGLRIEGMSLEKLLQEVPQELVSALNNPKDGLFSLSNDADNSDIETWHLSRGQFLLNGQFHHLVLLKQMTRELNR
QEVAVWKKVIRIISHELNNSVAPIASMVNSGRVITKELNDPKLKLIFDTIEDRSSHLSQFIFNYARFAKLPLPNKTCVDW
QTLTEQLKQHYQFELLGEFPQRPVSFDVIQMEQVLLNLLKNAHESGSDLDRISLEIRESSLSDPTQGLCIEVKDAGVGMS
ADVLSQALLPFYSTKQSGTGLGLPLCREIIEAHDGRISLHNRDEKGLCVSLWLPST

Sequences:

>Translated_456_residues
MSQISHISLRVKLIASCVSSVAMGLLLAFALQLWLARTAVITKAFFEPQSLYLVIFICCLLLVAWLSFLATRRLDTSLQA
LELGLLNFKDNDFSVSIPVSGNGQLRALAELFNESAQTLRKERQYIYQRELLLDKVIQSSPNVMLLLDDEQRIIYANDAA
RHLFNNGLRIEGMSLEKLLQEVPQELVSALNNPKDGLFSLSNDADNSDIETWHLSRGQFLLNGQFHHLVLLKQMTRELNR
QEVAVWKKVIRIISHELNNSVAPIASMVNSGRVITKELNDPKLKLIFDTIEDRSSHLSQFIFNYARFAKLPLPNKTCVDW
QTLTEQLKQHYQFELLGEFPQRPVSFDVIQMEQVLLNLLKNAHESGSDLDRISLEIRESSLSDPTQGLCIEVKDAGVGMS
ADVLSQALLPFYSTKQSGTGLGLPLCREIIEAHDGRISLHNRDEKGLCVSLWLPST
>Mature_455_residues
SQISHISLRVKLIASCVSSVAMGLLLAFALQLWLARTAVITKAFFEPQSLYLVIFICCLLLVAWLSFLATRRLDTSLQAL
ELGLLNFKDNDFSVSIPVSGNGQLRALAELFNESAQTLRKERQYIYQRELLLDKVIQSSPNVMLLLDDEQRIIYANDAAR
HLFNNGLRIEGMSLEKLLQEVPQELVSALNNPKDGLFSLSNDADNSDIETWHLSRGQFLLNGQFHHLVLLKQMTRELNRQ
EVAVWKKVIRIISHELNNSVAPIASMVNSGRVITKELNDPKLKLIFDTIEDRSSHLSQFIFNYARFAKLPLPNKTCVDWQ
TLTEQLKQHYQFELLGEFPQRPVSFDVIQMEQVLLNLLKNAHESGSDLDRISLEIRESSLSDPTQGLCIEVKDAGVGMSA
DVLSQALLPFYSTKQSGTGLGLPLCREIIEAHDGRISLHNRDEKGLCVSLWLPST

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=111, Percent_Identity=37.8378378378378, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788549, Length=242, Percent_Identity=28.9256198347107, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51468; Mature: 51337

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQISHISLRVKLIASCVSSVAMGLLLAFALQLWLARTAVITKAFFEPQSLYLVIFICCL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LLVAWLSFLATRRLDTSLQALELGLLNFKDNDFSVSIPVSGNGQLRALAELFNESAQTLR
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHH
KERQYIYQRELLLDKVIQSSPNVMLLLDDEQRIIYANDAARHLFNNGLRIEGMSLEKLLQ
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECHHHHHHHCCCCEEECCCHHHHHH
EVPQELVSALNNPKDGLFSLSNDADNSDIETWHLSRGQFLLNGQFHHLVLLKQMTRELNR
HHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEECCCCEEECCCHHHHHHHHHHHHHHHH
QEVAVWKKVIRIISHELNNSVAPIASMVNSGRVITKELNDPKLKLIFDTIEDRSSHLSQF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHH
IFNYARFAKLPLPNKTCVDWQTLTEQLKQHYQFELLGEFPQRPVSFDVIQMEQVLLNLLK
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
NAHESGSDLDRISLEIRESSLSDPTQGLCIEVKDAGVGMSADVLSQALLPFYSTKQSGTG
HHCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
LGLPLCREIIEAHDGRISLHNRDEKGLCVSLWLPST
CCHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCC
>Mature Secondary Structure 
SQISHISLRVKLIASCVSSVAMGLLLAFALQLWLARTAVITKAFFEPQSLYLVIFICCL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LLVAWLSFLATRRLDTSLQALELGLLNFKDNDFSVSIPVSGNGQLRALAELFNESAQTLR
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHH
KERQYIYQRELLLDKVIQSSPNVMLLLDDEQRIIYANDAARHLFNNGLRIEGMSLEKLLQ
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECHHHHHHHCCCCEEECCCHHHHHH
EVPQELVSALNNPKDGLFSLSNDADNSDIETWHLSRGQFLLNGQFHHLVLLKQMTRELNR
HHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEECCCCEEECCCHHHHHHHHHHHHHHHH
QEVAVWKKVIRIISHELNNSVAPIASMVNSGRVITKELNDPKLKLIFDTIEDRSSHLSQF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHH
IFNYARFAKLPLPNKTCVDWQTLTEQLKQHYQFELLGEFPQRPVSFDVIQMEQVLLNLLK
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
NAHESGSDLDRISLEIRESSLSDPTQGLCIEVKDAGVGMSADVLSQALLPFYSTKQSGTG
HHCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
LGLPLCREIIEAHDGRISLHNRDEKGLCVSLWLPST
CCHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]