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The map label for this gene is macB [H]

Identifier: 167625344

GI number: 167625344

Start: 4181186

End: 4182397

Strand: Reverse

Name: macB [H]

Synonym: Shal_3433

Alternate gene names: 167625344

Gene position: 4182397-4181186 (Counterclockwise)

Preceding gene: 167625345

Following gene: 167625343

Centisome position: 80.02

GC content: 45.79

Gene sequence:

>1212_bases
ATGTTGCAAGTTAAACCCATTATGAGCATGTTGATGCGTAATAAAAGTGGCCCTCTATTGCTGCTTATTCAGATAATTTT
ATCGGTGGCGATAGTCGCAAATGCGAGTTTCATTATTAGCGAGCGTATCGGCCTAATGAGCCGCGAGTCGGGGATCGCAG
AGTCCGAAGTGTTTGACTTAACCATATATAACTTTGACGAGGAGATAGATCTCGCTAAGCAAAACCTATTAGATCTGGAG
ATCGTACGTAACCTCGATGGGGTCAAGTCGGCGACGTCAACCAGCATGACTCCCTTGAGCGGTGGTGGTTGGTCCTCTAA
CTTCTCCCACGGTAGTAATGAAGAAGATCGTAAAGACACCCCTAATGCTGCCATCTATTATGGTGATGAGCAGATGATCT
CGACATTAGGGATAAAACTGATAGCGGGACGTAACTTCTATCCCGATGAAGTCAGTAGTGGTGGTCCGGAACTCGCGAGT
TTAGCCATAGTGACTGCAGACTTTGCCAAAGAGACCTTTGGTGATGAGTCGGCACTTGGAAAAATCTTGTATCAGGGTAA
TATTGGCGACCAGCCGATGAAAATTATCGGCGTTGTAGAGCGTTTGCAGGGCGCTTGGGTCAATAACTCCAACCTAAACA
ATAGCATTATTCTCAATGTGGAGCTGGGCTGGGCCTTTACCCGTTTTTTAGTGCGCGCCGATGAGTCTGCCATTGTTGGG
CTTAAAGAGGCCATACCTGCAGCGCTGCATAAAGAGCATCCTAATCGCGTAGTACAAGGATTTACGACGATTAGTGAGTA
CAGAAAAAGTGTATATCGTGACCATGAATTGATGGCAACTGTATTGTCTATGATGGTGGTACTACTGCTACTCATTACTT
CATTAGGTCTTGCTGGTATGGTGATGTTTAATATCGAGCGCCGGACTAAACAGATAGGTACACGCCGCGCCCTTGGGGCT
AAGAAACGTGACATTATTAGTTTCTTTTTGGTGGAGAATTACTTGTTGTGCCTAACTGGCGGCTTACTCGGAAGCTTAGT
GGCCGTGCAGCTTGGTCAGCAGCTGATGACGTTTTATAGTTTGCCTAAACTTGAGCTTATCTATCCGTTAGTGACGGTGG
CAGGTTTATTTGTATTAACCACTATTGCAGTGATATTTCCTGCACAAAAAGCGGCAAAGATTTCACCCGCAATAGCCACT
CGCAGTGTGTAA

Upstream 100 bases:

>100_bases
CCATTATTGCCGGAATTTATCCTGCATGGCGAATATGTAGCACCAATCCCAGTGTCTATCTCAAGAGCCAATGATTTACA
GAGTGAGAAAGGAACTTACT

Downstream 100 bases:

>100_bases
CCCGCTACTGCCAATACCAAAAAATGATATCTAAATGAAAGCCAAATGTGAGCAGAGCTTTAACTCTGTTTGGCTTTGAG
TTAGTTTTATAATTAGTCAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MLQVKPIMSMLMRNKSGPLLLLIQIILSVAIVANASFIISERIGLMSRESGIAESEVFDLTIYNFDEEIDLAKQNLLDLE
IVRNLDGVKSATSTSMTPLSGGGWSSNFSHGSNEEDRKDTPNAAIYYGDEQMISTLGIKLIAGRNFYPDEVSSGGPELAS
LAIVTADFAKETFGDESALGKILYQGNIGDQPMKIIGVVERLQGAWVNNSNLNNSIILNVELGWAFTRFLVRADESAIVG
LKEAIPAALHKEHPNRVVQGFTTISEYRKSVYRDHELMATVLSMMVVLLLLITSLGLAGMVMFNIERRTKQIGTRRALGA
KKRDIISFFLVENYLLCLTGGLLGSLVAVQLGQQLMTFYSLPKLELIYPLVTVAGLFVLTTIAVIFPAQKAAKISPAIAT
RSV

Sequences:

>Translated_403_residues
MLQVKPIMSMLMRNKSGPLLLLIQIILSVAIVANASFIISERIGLMSRESGIAESEVFDLTIYNFDEEIDLAKQNLLDLE
IVRNLDGVKSATSTSMTPLSGGGWSSNFSHGSNEEDRKDTPNAAIYYGDEQMISTLGIKLIAGRNFYPDEVSSGGPELAS
LAIVTADFAKETFGDESALGKILYQGNIGDQPMKIIGVVERLQGAWVNNSNLNNSIILNVELGWAFTRFLVRADESAIVG
LKEAIPAALHKEHPNRVVQGFTTISEYRKSVYRDHELMATVLSMMVVLLLLITSLGLAGMVMFNIERRTKQIGTRRALGA
KKRDIISFFLVENYLLCLTGGLLGSLVAVQLGQQLMTFYSLPKLELIYPLVTVAGLFVLTTIAVIFPAQKAAKISPAIAT
RSV
>Mature_403_residues
MLQVKPIMSMLMRNKSGPLLLLIQIILSVAIVANASFIISERIGLMSRESGIAESEVFDLTIYNFDEEIDLAKQNLLDLE
IVRNLDGVKSATSTSMTPLSGGGWSSNFSHGSNEEDRKDTPNAAIYYGDEQMISTLGIKLIAGRNFYPDEVSSGGPELAS
LAIVTADFAKETFGDESALGKILYQGNIGDQPMKIIGVVERLQGAWVNNSNLNNSIILNVELGWAFTRFLVRADESAIVG
LKEAIPAALHKEHPNRVVQGFTTISEYRKSVYRDHELMATVLSMMVVLLLLITSLGLAGMVMFNIERRTKQIGTRRALGA
KKRDIISFFLVENYLLCLTGGLLGSLVAVQLGQQLMTFYSLPKLELIYPLVTVAGLFVLTTIAVIFPAQKAAKISPAIAT
RSV

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=227, Percent_Identity=26.8722466960352, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44036; Mature: 44036

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQVKPIMSMLMRNKSGPLLLLIQIILSVAIVANASFIISERIGLMSRESGIAESEVFDL
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEE
TIYNFDEEIDLAKQNLLDLEIVRNLDGVKSATSTSMTPLSGGGWSSNFSHGSNEEDRKDT
EEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PNAAIYYGDEQMISTLGIKLIAGRNFYPDEVSSGGPELASLAIVTADFAKETFGDESALG
CCEEEEECCHHHHHHHCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
KILYQGNIGDQPMKIIGVVERLQGAWVNNSNLNNSIILNVELGWAFTRFLVRADESAIVG
HEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEHHHHHHHHHHCCCHHHHH
LKEAIPAALHKEHPNRVVQGFTTISEYRKSVYRDHELMATVLSMMVVLLLLITSLGLAGM
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMFNIERRTKQIGTRRALGAKKRDIISFFLVENYLLCLTGGLLGSLVAVQLGQQLMTFYS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LPKLELIYPLVTVAGLFVLTTIAVIFPAQKAAKISPAIATRSV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHCCCC
>Mature Secondary Structure
MLQVKPIMSMLMRNKSGPLLLLIQIILSVAIVANASFIISERIGLMSRESGIAESEVFDL
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEE
TIYNFDEEIDLAKQNLLDLEIVRNLDGVKSATSTSMTPLSGGGWSSNFSHGSNEEDRKDT
EEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PNAAIYYGDEQMISTLGIKLIAGRNFYPDEVSSGGPELASLAIVTADFAKETFGDESALG
CCEEEEECCHHHHHHHCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
KILYQGNIGDQPMKIIGVVERLQGAWVNNSNLNNSIILNVELGWAFTRFLVRADESAIVG
HEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEHHHHHHHHHHCCCHHHHH
LKEAIPAALHKEHPNRVVQGFTTISEYRKSVYRDHELMATVLSMMVVLLLLITSLGLAGM
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMFNIERRTKQIGTRRALGAKKRDIISFFLVENYLLCLTGGLLGSLVAVQLGQQLMTFYS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LPKLELIYPLVTVAGLFVLTTIAVIFPAQKAAKISPAIATRSV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]