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The map label for this gene is asnC

Identifier: 167624184

GI number: 167624184

Start: 2741469

End: 2742869

Strand: Direct

Name: asnC

Synonym: Shal_2260

Alternate gene names: 167624184

Gene position: 2741469-2742869 (Clockwise)

Preceding gene: 167624182

Following gene: 167624185

Centisome position: 52.45

GC content: 44.9

Gene sequence:

>1401_bases
ATGAGCATTACATCTGTCGCTTCTGTGTTTAAAGGTGACTTTGCGATTGGTTCGCAAATCACAGTACGTGGCTGGGTTAG
ATCCCGCCGCGATTCTAAAGCAGGGATCTCATTCCTCGCTGTTTATGATGGTTCATGTTTCGATCCTATTCAGGGTGTTG
TACCAAATAATCTAGAAAATTACACCAACGAAGTGTTAAAGCTTACTGCTGGTTGCTCTGTCGTAATGACAGGTGAAGTT
GTTGAGTCTCCAGGTAAAGGTCAAGCATTTGAGATGCAAGTGACCAAACTTGAAGTCGTAGGCTTTGTGGAAGATCCTGA
CACTTATCCAATGGCTGCCAAGCGCCACTCAATTGAATATCTACGCGAGCTTGCTCACCTACGTCCACGCACTAATATTA
TTGGCGCCGTGGCTCGTGTGCGTAACTGTTTATCTCAAGCTATCCACCGCTTTTATAATGAGCAAGGATATATCTGGGTT
TCTACGCCACTGATCACCGCTTCTGATACCGAAGGTGCAGGTGAGATGTTCCGTGTTTCAACTCTTGATTTAGAAAACCT
TCCTCGCACAGATAAAGGCACCGTTGATTACAGCGAAGACTTCTTCGGTAAAGAATCATTCCTAACCGTATCGGGCCAGC
TTAATGCTGAAACCTACGCATGTGCATTGTCAAAGGTTTATACTTTTGGTCCGACATTCCGTGCAGAGAACTCAAACACT
AGCCGTCACTTGGCTGAATTTTGGATGGTTGAGCCTGAAGTGGCTTTCGCCAACCTAGATGATGCTGCAAAACTTGCTGA
AGACATGCTTAAGTATTGCTTTAAGGCAGTGCTTGAAGAGCGTCGTGATGATCTTGAGTTCTTCGCCCAGCGCGTTGAGA
AAACAGCTATTGAGCGCCTAGAAGCGTTTGTAAGCAGTGATTTTGCTCAAATTGATTACACCGATGCGATTGAAATTCTT
AAAGCTTGTGACAAAGACTTTGAGTATGACGTTGAATGGGGTATCGACTTACATTCAGAGCATGAGCGTTATCTTGCAGA
AGAACACTTTAAAGCCCCTGTTGTTGTTAAAAACTACCCGAAAGACATTAAAGCATTCTACATGCGCTTAAACGATGACG
GTAAAACAGTTGCTGCTATGGACGTACTTGCTCCTGGTATTGGTGAAATCATCGGTGGTGCTCAGCGTGAAGAGCGTTTA
GATGTACTCGATGCGCGTCTTGCTGAAATGGAACTAAGCCAAGAAGATTACTGGTGGTACCGTGACCTACGTCGCTATGG
CACAGTCCCTCATGCTGGTTTTGGTTTAGGCTTTGAGCGTTTGGTTTCTTATGTAACTGGTGTGTCTAACATCCGTGACG
TGATCCCATTCCCACGCTCTCCAAAATCTGCTAACTTCTAA

Upstream 100 bases:

>100_bases
TACCAAGATACCCTACTTTCCACTTGAGAAAAGCGTTTATACAGGTAATATAAACCTCCAAATTATTTACAAAAACGTTT
CGTTGGAGAACTAAGCAACA

Downstream 100 bases:

>100_bases
TCTGTTAACTCACAGAATTAGTAGCTTACAGAACTGCTAGCTTACCGGTAAGCTAGCAACGATATTAAAGCCTCTTTCAT
TATATGTCAGAGGTTTTTTT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSITSVASVFKGDFAIGSQITVRGWVRSRRDSKAGISFLAVYDGSCFDPIQGVVPNNLENYTNEVLKLTAGCSVVMTGEV
VESPGKGQAFEMQVTKLEVVGFVEDPDTYPMAAKRHSIEYLRELAHLRPRTNIIGAVARVRNCLSQAIHRFYNEQGYIWV
STPLITASDTEGAGEMFRVSTLDLENLPRTDKGTVDYSEDFFGKESFLTVSGQLNAETYACALSKVYTFGPTFRAENSNT
SRHLAEFWMVEPEVAFANLDDAAKLAEDMLKYCFKAVLEERRDDLEFFAQRVEKTAIERLEAFVSSDFAQIDYTDAIEIL
KACDKDFEYDVEWGIDLHSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGAQREERL
DVLDARLAEMELSQEDYWWYRDLRRYGTVPHAGFGLGFERLVSYVTGVSNIRDVIPFPRSPKSANF

Sequences:

>Translated_466_residues
MSITSVASVFKGDFAIGSQITVRGWVRSRRDSKAGISFLAVYDGSCFDPIQGVVPNNLENYTNEVLKLTAGCSVVMTGEV
VESPGKGQAFEMQVTKLEVVGFVEDPDTYPMAAKRHSIEYLRELAHLRPRTNIIGAVARVRNCLSQAIHRFYNEQGYIWV
STPLITASDTEGAGEMFRVSTLDLENLPRTDKGTVDYSEDFFGKESFLTVSGQLNAETYACALSKVYTFGPTFRAENSNT
SRHLAEFWMVEPEVAFANLDDAAKLAEDMLKYCFKAVLEERRDDLEFFAQRVEKTAIERLEAFVSSDFAQIDYTDAIEIL
KACDKDFEYDVEWGIDLHSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGAQREERL
DVLDARLAEMELSQEDYWWYRDLRRYGTVPHAGFGLGFERLVSYVTGVSNIRDVIPFPRSPKSANF
>Mature_465_residues
SITSVASVFKGDFAIGSQITVRGWVRSRRDSKAGISFLAVYDGSCFDPIQGVVPNNLENYTNEVLKLTAGCSVVMTGEVV
ESPGKGQAFEMQVTKLEVVGFVEDPDTYPMAAKRHSIEYLRELAHLRPRTNIIGAVARVRNCLSQAIHRFYNEQGYIWVS
TPLITASDTEGAGEMFRVSTLDLENLPRTDKGTVDYSEDFFGKESFLTVSGQLNAETYACALSKVYTFGPTFRAENSNTS
RHLAEFWMVEPEVAFANLDDAAKLAEDMLKYCFKAVLEERRDDLEFFAQRVEKTAIERLEAFVSSDFAQIDYTDAIEILK
ACDKDFEYDVEWGIDLHSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGAQREERLD
VLDARLAEMELSQEDYWWYRDLRRYGTVPHAGFGLGFERLVSYVTGVSNIRDVIPFPRSPKSANF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=464, Percent_Identity=43.1034482758621, Blast_Score=386, Evalue=1e-107,
Organism=Homo sapiens, GI4758762, Length=452, Percent_Identity=28.5398230088496, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI45439306, Length=342, Percent_Identity=27.7777777777778, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=78.3261802575107, Blast_Score=794, Evalue=0.0,
Organism=Escherichia coli, GI1790571, Length=367, Percent_Identity=24.7956403269755, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71984122, Length=451, Percent_Identity=29.490022172949, Blast_Score=184, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI17556372, Length=434, Percent_Identity=31.3364055299539, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17551876, Length=342, Percent_Identity=27.4853801169591, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6319872, Length=471, Percent_Identity=37.5796178343949, Blast_Score=296, Evalue=4e-81,
Organism=Saccharomyces cerevisiae, GI6321807, Length=453, Percent_Identity=31.1258278145695, Blast_Score=203, Evalue=6e-53,
Organism=Saccharomyces cerevisiae, GI6323011, Length=482, Percent_Identity=26.1410788381743, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI19922416, Length=464, Percent_Identity=34.4827586206897, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI19921528, Length=473, Percent_Identity=27.2727272727273, Blast_Score=172, Evalue=5e-43,
Organism=Drosophila melanogaster, GI17136276, Length=343, Percent_Identity=28.5714285714286, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_SHEHH (B0TUU1)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001674478.1
- ProteinModelPortal:   B0TUU1
- SMR:   B0TUU1
- GeneID:   5903507
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_2260
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- ProtClustDB:   PRK03932
- BioCyc:   SHAL458817:SHAL_2260-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 52542; Mature: 52410

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITSVASVFKGDFAIGSQITVRGWVRSRRDSKAGISFLAVYDGSCFDPIQGVVPNNLEN
CCHHHHHHHHCCCCCCCCCEEEHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHH
YTNEVLKLTAGCSVVMTGEVVESPGKGQAFEMQVTKLEVVGFVEDPDTYPMAAKRHSIEY
HHHHHHHHHCCCEEEEECHHHCCCCCCCEEEEEEEEEEEEEEECCCCCCCCHHHHHHHHH
LRELAHLRPRTNIIGAVARVRNCLSQAIHRFYNEQGYIWVSTPLITASDTEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEECCCCCCCCEEEEE
TLDLENLPRTDKGTVDYSEDFFGKESFLTVSGQLNAETYACALSKVYTFGPTFRAENSNT
EECHHCCCCCCCCCCCCCHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMVEPEVAFANLDDAAKLAEDMLKYCFKAVLEERRDDLEFFAQRVEKTAIERL
HHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAFVSSDFAQIDYTDAIEILKACDKDFEYDVEWGIDLHSEHERYLAEEHFKAPVVVKNYP
HHHHHCCCHHCCHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGAQREERLDVLDARLAEMELSQEDYWWY
HHHHHHEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
RDLRRYGTVPHAGFGLGFERLVSYVTGVSNIRDVIPFPRSPKSANF
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SITSVASVFKGDFAIGSQITVRGWVRSRRDSKAGISFLAVYDGSCFDPIQGVVPNNLEN
CHHHHHHHHCCCCCCCCCEEEHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHH
YTNEVLKLTAGCSVVMTGEVVESPGKGQAFEMQVTKLEVVGFVEDPDTYPMAAKRHSIEY
HHHHHHHHHCCCEEEEECHHHCCCCCCCEEEEEEEEEEEEEEECCCCCCCCHHHHHHHHH
LRELAHLRPRTNIIGAVARVRNCLSQAIHRFYNEQGYIWVSTPLITASDTEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEECCCCCCCCEEEEE
TLDLENLPRTDKGTVDYSEDFFGKESFLTVSGQLNAETYACALSKVYTFGPTFRAENSNT
EECHHCCCCCCCCCCCCCHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMVEPEVAFANLDDAAKLAEDMLKYCFKAVLEERRDDLEFFAQRVEKTAIERL
HHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAFVSSDFAQIDYTDAIEILKACDKDFEYDVEWGIDLHSEHERYLAEEHFKAPVVVKNYP
HHHHHCCCHHCCHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGAQREERLDVLDARLAEMELSQEDYWWY
HHHHHHEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
RDLRRYGTVPHAGFGLGFERLVSYVTGVSNIRDVIPFPRSPKSANF
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA