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The map label for this gene is nudL [H]

Identifier: 167624182

GI number: 167624182

Start: 2740296

End: 2740877

Strand: Direct

Name: nudL [H]

Synonym: Shal_2258

Alternate gene names: 167624182

Gene position: 2740296-2740877 (Clockwise)

Preceding gene: 167624181

Following gene: 167624184

Centisome position: 52.43

GC content: 47.59

Gene sequence:

>582_bases
ATGGATCTGGCGGAGTTTAGACTCAGGTATACTCTTAATGCTCTGCCAGAACTTGATTTAATCGAGTTAGATCAGCAGCT
TCGTCAAGCCGCGGTGTTAATCGCCTTGTATGAAGTCGATAATCGTCTCGAGCTGATCTTAACCCGCAGGCCCACACACC
TTCGTGCCCACCCCGGGCAAATTAGCTTTCCCGGCGGCAAAGTTGAACAGTCTGATTTAAGCTATCAGGCAACGGCACTA
CGAGAGGCTGAAGAAGAGATAGGGTTACTCAGCAGTAATGTCGAGGTCATAGGTGCACTCCCGCCCCACAAAACCTTTAC
CGGTTTTGAGATCACCCCCTTTGTTGGCATCGTTAAGCAAACATTTACGCCCATTATAGATCCCGGTGAAGTGGATGAGT
ATTTCACTGTGCCACTTTCTTTTTTAATGCAAGGTTATAATCGTCATACACAAAGGTTTAAGCGTAAGGGGATCCAATAC
CCTGTTCACTTTATTCCCTATAAGCAGCATTTCATCTGGGGGGCGACTGCGGCGATGATCGACCTTCTTTGTAGGCAGCT
AAGCTGCGAGAAAGCTGACTAA

Upstream 100 bases:

>100_bases
TGATAAAATCAGTCGTATATTGCCCGTTCTTTCTAACCTAAACCGTTAATAAGTCGTATATCAACCAGCCCTATACGGGG
TTAATAGCAAAGGATAAGTT

Downstream 100 bases:

>100_bases
AATCAGTTGCGCTAGCTAAGTTTTCTAGGCTCTAAGATCTAAACTCCAAACAGAAAATTCTAAACAGGTAAACTGCTAAG
GTTTGAAAACTCAATCCTTA

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MDLAEFRLRYTLNALPELDLIELDQQLRQAAVLIALYEVDNRLELILTRRPTHLRAHPGQISFPGGKVEQSDLSYQATAL
REAEEEIGLLSSNVEVIGALPPHKTFTGFEITPFVGIVKQTFTPIIDPGEVDEYFTVPLSFLMQGYNRHTQRFKRKGIQY
PVHFIPYKQHFIWGATAAMIDLLCRQLSCEKAD

Sequences:

>Translated_193_residues
MDLAEFRLRYTLNALPELDLIELDQQLRQAAVLIALYEVDNRLELILTRRPTHLRAHPGQISFPGGKVEQSDLSYQATAL
REAEEEIGLLSSNVEVIGALPPHKTFTGFEITPFVGIVKQTFTPIIDPGEVDEYFTVPLSFLMQGYNRHTQRFKRKGIQY
PVHFIPYKQHFIWGATAAMIDLLCRQLSCEKAD
>Mature_193_residues
MDLAEFRLRYTLNALPELDLIELDQQLRQAAVLIALYEVDNRLELILTRRPTHLRAHPGQISFPGGKVEQSDLSYQATAL
REAEEEIGLLSSNVEVIGALPPHKTFTGFEITPFVGIVKQTFTPIIDPGEVDEYFTVPLSFLMQGYNRHTQRFKRKGIQY
PVHFIPYKQHFIWGATAAMIDLLCRQLSCEKAD

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=137, Percent_Identity=37.956204379562, Blast_Score=95, Evalue=4e-20,
Organism=Escherichia coli, GI1788115, Length=163, Percent_Identity=41.7177914110429, Blast_Score=100, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17536993, Length=169, Percent_Identity=30.1775147928994, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17510677, Length=159, Percent_Identity=32.0754716981132, Blast_Score=73, Evalue=9e-14,
Organism=Drosophila melanogaster, GI18859683, Length=179, Percent_Identity=37.9888268156425, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 22029; Mature: 22029

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLAEFRLRYTLNALPELDLIELDQQLRQAAVLIALYEVDNRLELILTRRPTHLRAHPGQ
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCEEECCCCE
ISFPGGKVEQSDLSYQATALREAEEEIGLLSSNVEVIGALPPHKTFTGFEITPFVGIVKQ
EECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHH
TFTPIIDPGEVDEYFTVPLSFLMQGYNRHTQRFKRKGIQYPVHFIPYKQHFIWGATAAMI
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHH
DLLCRQLSCEKAD
HHHHHHHCCCCCC
>Mature Secondary Structure
MDLAEFRLRYTLNALPELDLIELDQQLRQAAVLIALYEVDNRLELILTRRPTHLRAHPGQ
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCEEECCCCE
ISFPGGKVEQSDLSYQATALREAEEEIGLLSSNVEVIGALPPHKTFTGFEITPFVGIVKQ
EECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHH
TFTPIIDPGEVDEYFTVPLSFLMQGYNRHTQRFKRKGIQYPVHFIPYKQHFIWGATAAMI
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHH
DLLCRQLSCEKAD
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA