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The map label for this gene is pabB [H]

Identifier: 167624181

GI number: 167624181

Start: 2738607

End: 2740244

Strand: Direct

Name: pabB [H]

Synonym: Shal_2257

Alternate gene names: 167624181

Gene position: 2738607-2740244 (Clockwise)

Preceding gene: 167624178

Following gene: 167624182

Centisome position: 52.39

GC content: 44.51

Gene sequence:

>1638_bases
ATGAACAAATTGACGCAAAATGCAGTTTTTACAAAGCGTCTTGATTGGAATTTAAGCACAACAGAATTATTTGAGCATTT
TTCAGCCTTGCCTTGGTCAGTTTTGCTCGATTCTGCCAATGCTGCTCACATAGATGCTAAATTCGATGTGATCTGTGCCG
AGCCTGTAGCCACTATAGTAAACCATGGCCAATCAACCACTATTACACGCTCAACTGACAGACAACCGCTATTTAGGTTC
GATCAACAACCAGCTGACAACGACTTAGATAACCCAAAAAATGAGTACGCAGAAAAAGCCGCTAAACATTCGGTATCGAG
TCGCGATCCTTTTGATCTCTTAAATGAGTTGTTGGCAGAGTACTACCCAACACAGAAATACAGCCCCTTCATCTTTAGTG
GCGGCGTTATGGGAAGTTTTAGCTACGATATTGGCCGAGTCATTGAAAAGCTCCCCCAAATTGCGGCTAACGATATTTCG
CTGCCTGAGATGAACCTTGCTTGTTACGACTGGGCGCTAATTTTTGACTATAAAACCCAAAGCTGGCAACTGGTTCACTA
TCAATCACAACAAGCTTTGGAGGCTCTTGAGCTGAGGCTAAATCAGCTTATCGAGCCTAGCCTGTTGGTTAAAGTCAATT
CGACGCTTGAAAGCTCCCTGAACGTAGAGAACTCTCTGAACTTAGAAAACACTCAGAAGTTAAATACCTCTAAAAATTCA
GAAACAGACCAACAAGATAACCCTATAGCGAATAGTGCTTTTAGGCTTAACGGTCAATGGCGTAATCAGCTTTCTGAACA
GGCTTATAAAGACAAGTTTGAACAGGTACAAGCATATCTGCTCAGTGGCGATTGTTATCAAATTAACCTAACTCAACGGT
TTAGTGCCTCGTATACGGGTAACGAATGGCAAGCTTATAAAGCATTGCGAGAGAGTAATGGTGCACCATTTTCAGCGTTT
ATCCGCTTAGAGGGCCATGCGCTACTCTCCATCTCGCCAGAGCGTTTTATCCAGCATAAAAATGGCGACATTCAAACTAA
GCCGATTAAAGGCACTATGCCAAGAGGTGTTGACCCACATAGTGATAGTGAACTTGCCGCTCAACTAAAGGCTTCAGAGA
AAGATCGGGCTGAGAATGTCATGATTGTCGACCTGCTACGAAACGATATAGGTAAAGTAGCACTGCCTGGCAGTGTTGCG
GTCCCTCACCTATTTGAGGTTGAAAGCTTTCCTGCGGTGCACCATCTGGTCAGCACGGTTACCGCGAAACTTAAACCAGA
GCTAAACCCTACAGATCTATTGAGAGCATGTTTCCCCGGGGGCTCAATAACAGGCGCGCCAAAAATTCGAGCGATGTCGA
TTATTGAAGAGCTTGAACCCTCTAGAAGAAGCCTCTATTGTGGCTCTATAGGCTATATAAGCCAAGACGGTACTATGGAT
ACCAGCATTACTATCCGCACGTTAGTAGCCCAAAGAGACGAAACCAGTCATCTAGCTCCCCTTAACGGAAGGCAAGGCAT
CATACATTGCTGGGCTGGAGGCGGTATCGTCGCCGATTCTAAGGTCGATGCTGAGTATCAGGAGAGTTTTGATAAAATCA
GTCGTATATTGCCCGTTCTTTCTAACCTAAACCGTTAA

Upstream 100 bases:

>100_bases
CCATTAAAGCTCACGTGTTTTGTTTTTATTACTTGTGTAAGCAATATGATACTCTTTCGCGAGTTTGAGTTAAACATCAC
ATTTTAGATAGGGTTAACAG

Downstream 100 bases:

>100_bases
TAAGTCGTATATCAACCAGCCCTATACGGGGTTAATAGCAAAGGATAAGTTATGGATCTGGCGGAGTTTAGACTCAGGTA
TACTCTTAATGCTCTGCCAG

Product: para-aminobenzoate synthase subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MNKLTQNAVFTKRLDWNLSTTELFEHFSALPWSVLLDSANAAHIDAKFDVICAEPVATIVNHGQSTTITRSTDRQPLFRF
DQQPADNDLDNPKNEYAEKAAKHSVSSRDPFDLLNELLAEYYPTQKYSPFIFSGGVMGSFSYDIGRVIEKLPQIAANDIS
LPEMNLACYDWALIFDYKTQSWQLVHYQSQQALEALELRLNQLIEPSLLVKVNSTLESSLNVENSLNLENTQKLNTSKNS
ETDQQDNPIANSAFRLNGQWRNQLSEQAYKDKFEQVQAYLLSGDCYQINLTQRFSASYTGNEWQAYKALRESNGAPFSAF
IRLEGHALLSISPERFIQHKNGDIQTKPIKGTMPRGVDPHSDSELAAQLKASEKDRAENVMIVDLLRNDIGKVALPGSVA
VPHLFEVESFPAVHHLVSTVTAKLKPELNPTDLLRACFPGGSITGAPKIRAMSIIEELEPSRRSLYCGSIGYISQDGTMD
TSITIRTLVAQRDETSHLAPLNGRQGIIHCWAGGGIVADSKVDAEYQESFDKISRILPVLSNLNR

Sequences:

>Translated_545_residues
MNKLTQNAVFTKRLDWNLSTTELFEHFSALPWSVLLDSANAAHIDAKFDVICAEPVATIVNHGQSTTITRSTDRQPLFRF
DQQPADNDLDNPKNEYAEKAAKHSVSSRDPFDLLNELLAEYYPTQKYSPFIFSGGVMGSFSYDIGRVIEKLPQIAANDIS
LPEMNLACYDWALIFDYKTQSWQLVHYQSQQALEALELRLNQLIEPSLLVKVNSTLESSLNVENSLNLENTQKLNTSKNS
ETDQQDNPIANSAFRLNGQWRNQLSEQAYKDKFEQVQAYLLSGDCYQINLTQRFSASYTGNEWQAYKALRESNGAPFSAF
IRLEGHALLSISPERFIQHKNGDIQTKPIKGTMPRGVDPHSDSELAAQLKASEKDRAENVMIVDLLRNDIGKVALPGSVA
VPHLFEVESFPAVHHLVSTVTAKLKPELNPTDLLRACFPGGSITGAPKIRAMSIIEELEPSRRSLYCGSIGYISQDGTMD
TSITIRTLVAQRDETSHLAPLNGRQGIIHCWAGGGIVADSKVDAEYQESFDKISRILPVLSNLNR
>Mature_545_residues
MNKLTQNAVFTKRLDWNLSTTELFEHFSALPWSVLLDSANAAHIDAKFDVICAEPVATIVNHGQSTTITRSTDRQPLFRF
DQQPADNDLDNPKNEYAEKAAKHSVSSRDPFDLLNELLAEYYPTQKYSPFIFSGGVMGSFSYDIGRVIEKLPQIAANDIS
LPEMNLACYDWALIFDYKTQSWQLVHYQSQQALEALELRLNQLIEPSLLVKVNSTLESSLNVENSLNLENTQKLNTSKNS
ETDQQDNPIANSAFRLNGQWRNQLSEQAYKDKFEQVQAYLLSGDCYQINLTQRFSASYTGNEWQAYKALRESNGAPFSAF
IRLEGHALLSISPERFIQHKNGDIQTKPIKGTMPRGVDPHSDSELAAQLKASEKDRAENVMIVDLLRNDIGKVALPGSVA
VPHLFEVESFPAVHHLVSTVTAKLKPELNPTDLLRACFPGGSITGAPKIRAMSIIEELEPSRRSLYCGSIGYISQDGTMD
TSITIRTLVAQRDETSHLAPLNGRQGIIHCWAGGGIVADSKVDAEYQESFDKISRILPVLSNLNR

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=536, Percent_Identity=46.0820895522388, Blast_Score=442, Evalue=1e-125,
Organism=Escherichia coli, GI1787518, Length=458, Percent_Identity=28.6026200873362, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI1786809, Length=221, Percent_Identity=28.9592760180996, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI87082077, Length=232, Percent_Identity=23.7068965517241, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320935, Length=472, Percent_Identity=29.2372881355932, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6324361, Length=300, Percent_Identity=29, Blast_Score=120, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 60854; Mature: 60854

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLTQNAVFTKRLDWNLSTTELFEHFSALPWSVLLDSANAAHIDAKFDVICAEPVATIV
CCCCCCCCCEEEECCCCCCHHHHHHHHHCCCHHHEECCCCCEEECCEEEEEECCHHHHHH
NHGQSTTITRSTDRQPLFRFDQQPADNDLDNPKNEYAEKAAKHSVSSRDPFDLLNELLAE
HCCCCCEEECCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
YYPTQKYSPFIFSGGVMGSFSYDIGRVIEKLPQIAANDISLPEMNLACYDWALIFDYKTQ
HCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEEECCC
SWQLVHYQSQQALEALELRLNQLIEPSLLVKVNSTLESSLNVENSLNLENTQKLNTSKNS
CEEEEEECHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHCCCCCCCCCCCCHHCCCCCCC
ETDQQDNPIANSAFRLNGQWRNQLSEQAYKDKFEQVQAYLLSGDCYQINLTQRFSASYTG
CCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCC
NEWQAYKALRESNGAPFSAFIRLEGHALLSISPERFIQHKNGDIQTKPIKGTMPRGVDPH
CHHHHHHHHHHCCCCCEEEEEEEECCEEEEECHHHHHHCCCCCEEECCCCCCCCCCCCCC
SDSELAAQLKASEKDRAENVMIVDLLRNDIGKVALPGSVAVPHLFEVESFPAVHHLVSTV
CCHHHHHHHHCCCHHHHCCEEEHHHHHHCCCCEECCCCCCCCCEEECCCCHHHHHHHHHH
TAKLKPELNPTDLLRACFPGGSITGAPKIRAMSIIEELEPSRRSLYCGSIGYISQDGTMD
HHHCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHEEEECCCCEECCCCCCC
TSITIRTLVAQRDETSHLAPLNGRQGIIHCWAGGGIVADSKVDAEYQESFDKISRILPVL
CCEEEEEHHHCCCCCCCCCCCCCCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHH
SNLNR
HCCCC
>Mature Secondary Structure
MNKLTQNAVFTKRLDWNLSTTELFEHFSALPWSVLLDSANAAHIDAKFDVICAEPVATIV
CCCCCCCCCEEEECCCCCCHHHHHHHHHCCCHHHEECCCCCEEECCEEEEEECCHHHHHH
NHGQSTTITRSTDRQPLFRFDQQPADNDLDNPKNEYAEKAAKHSVSSRDPFDLLNELLAE
HCCCCCEEECCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
YYPTQKYSPFIFSGGVMGSFSYDIGRVIEKLPQIAANDISLPEMNLACYDWALIFDYKTQ
HCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEEECCC
SWQLVHYQSQQALEALELRLNQLIEPSLLVKVNSTLESSLNVENSLNLENTQKLNTSKNS
CEEEEEECHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHCCCCCCCCCCCCHHCCCCCCC
ETDQQDNPIANSAFRLNGQWRNQLSEQAYKDKFEQVQAYLLSGDCYQINLTQRFSASYTG
CCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCC
NEWQAYKALRESNGAPFSAFIRLEGHALLSISPERFIQHKNGDIQTKPIKGTMPRGVDPH
CHHHHHHHHHHCCCCCEEEEEEEECCEEEEECHHHHHHCCCCCEEECCCCCCCCCCCCCC
SDSELAAQLKASEKDRAENVMIVDLLRNDIGKVALPGSVAVPHLFEVESFPAVHHLVSTV
CCHHHHHHHHCCCHHHHCCEEEHHHHHHCCCCEECCCCCCCCCEEECCCCHHHHHHHHHH
TAKLKPELNPTDLLRACFPGGSITGAPKIRAMSIIEELEPSRRSLYCGSIGYISQDGTMD
HHHCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHEEEECCCCEECCCCCCC
TSITIRTLVAQRDETSHLAPLNGRQGIIHCWAGGGIVADSKVDAEYQESFDKISRILPVL
CCEEEEEHHHCCCCCCCCCCCCCCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHH
SNLNR
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]