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The map label for this gene is efp

Identifier: 167624169

GI number: 167624169

Start: 2720300

End: 2720860

Strand: Direct

Name: efp

Synonym: Shal_2245

Alternate gene names: 167624169

Gene position: 2720300-2720860 (Clockwise)

Preceding gene: 167624168

Following gene: 167624170

Centisome position: 52.04

GC content: 43.14

Gene sequence:

>561_bases
ATGAAAACTGCTCATGAACTCCGTCCTGGTAACGTGATCATGTTAGATGGCAGCCCATGGGTTGTTCAAAAAACTGAAAC
AACTCGTTCTGGCCGTAACGCTGCTATCGTTAAATTAAAGCTTAAGCACGTTCTACAAGACTCTTCTACTGAAAGCACCT
TCAAAGGTGAAGACAAGATGGAAGATATCATTCTAGAGCGTCTAGACTGTACTTACTCTTACTTCGCTGATCCTATGTAT
GTTTTCATGGATGCTGAATACAACCAGTACGACGTTGAAGCTGAAAACCTAGGCGATGCTGCTGCTTACATCGTTGACGG
TATGGAAGAAAATTGCCAAGTGACTTTCTACGAAGGTAAAGCAATTTCAGTTGAACTACCAACTTCAGTAGTACGTGAAG
TAACATACACAGAGCCTTCGGCTCGTGGTGATACTTCAGGTAAAGTAATGAAGCCAGCTACCATCACTGGTGGCGGCACG
CTAAGTGTTGCAGACTTCGTTAAGACTGGCGACATGATTGAAATTGATACTCGTACTAACGAGTTCAAGAAGCGCGTTTA
A

Upstream 100 bases:

>100_bases
CAATCAATGATGTAGATCTTGTTTCTCGACTAGTTCAATTCGTCAAAAATAGCTAAGATACTACGTTTAAATAGAAAAAC
CTAAAATAGGAAATAGTGTA

Downstream 100 bases:

>100_bases
TTTTTAAGCCATGCTTTGATAAAGCCAGCATATACGCTGGCTTTTTTTTGGCTGAAATTTGCCATCAATCTTCTGCCTAC
GCTCGATTACGCTCTAATGA

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MKTAHELRPGNVIMLDGSPWVVQKTETTRSGRNAAIVKLKLKHVLQDSSTESTFKGEDKMEDIILERLDCTYSYFADPMY
VFMDAEYNQYDVEAENLGDAAAYIVDGMEENCQVTFYEGKAISVELPTSVVREVTYTEPSARGDTSGKVMKPATITGGGT
LSVADFVKTGDMIEIDTRTNEFKKRV

Sequences:

>Translated_186_residues
MKTAHELRPGNVIMLDGSPWVVQKTETTRSGRNAAIVKLKLKHVLQDSSTESTFKGEDKMEDIILERLDCTYSYFADPMY
VFMDAEYNQYDVEAENLGDAAAYIVDGMEENCQVTFYEGKAISVELPTSVVREVTYTEPSARGDTSGKVMKPATITGGGT
LSVADFVKTGDMIEIDTRTNEFKKRV
>Mature_186_residues
MKTAHELRPGNVIMLDGSPWVVQKTETTRSGRNAAIVKLKLKHVLQDSSTESTFKGEDKMEDIILERLDCTYSYFADPMY
VFMDAEYNQYDVEAENLGDAAAYIVDGMEENCQVTFYEGKAISVELPTSVVREVTYTEPSARGDTSGKVMKPATITGGGT
LSVADFVKTGDMIEIDTRTNEFKKRV

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=184, Percent_Identity=35.8695652173913, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI87082061, Length=188, Percent_Identity=27.1276595744681, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_SHEHH (B0TUS6)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001674463.1
- ProteinModelPortal:   B0TUS6
- SMR:   B0TUS6
- GeneID:   5905961
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_2245
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- BioCyc:   SHAL458817:SHAL_2245-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20704; Mature: 20704

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTAHELRPGNVIMLDGSPWVVQKTETTRSGRNAAIVKLKLKHVLQDSSTESTFKGEDKM
CCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCEEEEEEEEHHHHCCCCCCCCCCCCHHH
EDIILERLDCTYSYFADPMYVFMDAEYNQYDVEAENLGDAAAYIVDGMEENCQVTFYEGK
HHHHHHHHCCCHHHHCCEEEEEEECCCCEEECCHHHCCCEEEEEECCCCCCCEEEEECCE
AISVELPTSVVREVTYTEPSARGDTSGKVMKPATITGGGTLSVADFVKTGDMIEIDTRTN
EEEEECCHHHHHHHHCCCCCCCCCCCCCEECCEEECCCCEEEHHHHHCCCCEEEEECCCC
EFKKRV
HHHHCC
>Mature Secondary Structure
MKTAHELRPGNVIMLDGSPWVVQKTETTRSGRNAAIVKLKLKHVLQDSSTESTFKGEDKM
CCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCEEEEEEEEHHHHCCCCCCCCCCCCHHH
EDIILERLDCTYSYFADPMYVFMDAEYNQYDVEAENLGDAAAYIVDGMEENCQVTFYEGK
HHHHHHHHCCCHHHHCCEEEEEEECCCCEEECCHHHCCCEEEEEECCCCCCCEEEEECCE
AISVELPTSVVREVTYTEPSARGDTSGKVMKPATITGGGTLSVADFVKTGDMIEIDTRTN
EEEEECCHHHHHHHHCCCCCCCCCCCCCEECCEEECCCCEEEHHHHHCCCCEEEEECCCC
EFKKRV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA