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The map label for this gene is yfbQ [H]

Identifier: 167624170

GI number: 167624170

Start: 2721215

End: 2722429

Strand: Direct

Name: yfbQ [H]

Synonym: Shal_2246

Alternate gene names: 167624170

Gene position: 2721215-2722429 (Clockwise)

Preceding gene: 167624169

Following gene: 167624171

Centisome position: 52.06

GC content: 45.84

Gene sequence:

>1215_bases
ATGCGCCCTATTATCAAATCCAATAAATTAGATTCTGTTTGTTATGACATTCGCGGTCCGGTGCATAAAGAAGCCCGTCG
ACTTGAAGATGAAGGTCATCGAATTCTAAAGCTTAACATCGGTAACCCAGCCCCATTTGGATTTGAGGCCCCAGAAGAGA
TCGTTCGTGATGTTATTCTGAACTTGCCAAGTGCACAGGGCTATTGTGAATCTAAAGGCCTGTTCTCGGCGCGTAAAGCC
ATCGTTCAGCACTACCAGTCTCAAGGTATTTTCGGTGTCGATATCGAAGATATCTATATTGGTAACGGCGTATCAGAATT
GATCGTTATGGCGATGCAAGGTCTACTTAACAGTGGTGATGAGATCCTAGTGCCTTCACCAGATTACCCGTTGTGGACTG
CGGCGGTTCACCTCTCGGGCGGTAAAGCGCAGCATTATCGTTGTGATGAAGAGTCAGACTGGTTCCCAGATCTTGAAGAC
ATCAAGAGTAAAATAACTCCTAGAACCCGTGGTATCGTTCTAATTAACCCGAATAATCCAACGGGCGCAGTTTACTCAAA
AGAGCTGATCCTTGAAGTCATTGAACTGTGTCGTCAAAACGACATGATTTTGTTTGCCGACGAGATCTACGACAAAATTC
TATATGATGAAGCTGAACATATTCCTGCAGCTAGTCTATCAGATGACATCTTAACGGTAACTTTTAATGGTTTATCTAAA
GTTTATCGTGCTGCAGGCTTTCGTGTTGGCTGGATGATGCTCACCGGGAATCTAAAAGCGGCTAAGAGTTACGTCGAGGG
CTTAGATATGCTGGCATCGATGCGCCTGTGCGCTAACGTGCCAAGTCAGCATGCGATCCAAACGGCATTAGGTGGCTATC
AGAGTATTCACGAATTAGTACAACCTGGTGGGCGCCTGCGTGTACAACGTGATGCCTGCGTTGAGATGCTTAACTCGATT
CCTGGTGTGAGCGTAAAAACGCCAAAAGGTGCCTTGTATGCCTTTGCTAAACTGGACCAAAAGAAGTTTAACCTGCGCGA
TGATGAGCGTTTAGTTCTCGACCTTCTCAAAGACCGCAAGATCTTACTGGTACAAGGTTCAGCGTTTAACTACCCGGAGC
CTGATCATGTTCGCGTGGTGTTCCTGCCTTATAAAGAAGAGCTGACCAAAGCGCTATCGGAATTCGGTGACTTCTTAGGA
AACTATAAGCAGTAG

Upstream 100 bases:

>100_bases
AGTGATTTAATCCTTTATTTGTCGATTGAATTTAGCTATTGTGCCTGCAACAAAGCCAAAGAGATGTTTGGCCCATATTT
TCAGCATTTTCGAGGTGTAG

Downstream 100 bases:

>100_bases
CAACGATAAGTAGCATCAAATTGAAGCTAGCGAACTAAGTGGCAAACTAAGTCGCGAACTAAGTCGCGAACTAAGTCGCG
AACTAAAACTAAGTAGCTAA

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MRPIIKSNKLDSVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVILNLPSAQGYCESKGLFSARKA
IVQHYQSQGIFGVDIEDIYIGNGVSELIVMAMQGLLNSGDEILVPSPDYPLWTAAVHLSGGKAQHYRCDEESDWFPDLED
IKSKITPRTRGIVLINPNNPTGAVYSKELILEVIELCRQNDMILFADEIYDKILYDEAEHIPAASLSDDILTVTFNGLSK
VYRAAGFRVGWMMLTGNLKAAKSYVEGLDMLASMRLCANVPSQHAIQTALGGYQSIHELVQPGGRLRVQRDACVEMLNSI
PGVSVKTPKGALYAFAKLDQKKFNLRDDERLVLDLLKDRKILLVQGSAFNYPEPDHVRVVFLPYKEELTKALSEFGDFLG
NYKQ

Sequences:

>Translated_404_residues
MRPIIKSNKLDSVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVILNLPSAQGYCESKGLFSARKA
IVQHYQSQGIFGVDIEDIYIGNGVSELIVMAMQGLLNSGDEILVPSPDYPLWTAAVHLSGGKAQHYRCDEESDWFPDLED
IKSKITPRTRGIVLINPNNPTGAVYSKELILEVIELCRQNDMILFADEIYDKILYDEAEHIPAASLSDDILTVTFNGLSK
VYRAAGFRVGWMMLTGNLKAAKSYVEGLDMLASMRLCANVPSQHAIQTALGGYQSIHELVQPGGRLRVQRDACVEMLNSI
PGVSVKTPKGALYAFAKLDQKKFNLRDDERLVLDLLKDRKILLVQGSAFNYPEPDHVRVVFLPYKEELTKALSEFGDFLG
NYKQ
>Mature_404_residues
MRPIIKSNKLDSVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVILNLPSAQGYCESKGLFSARKA
IVQHYQSQGIFGVDIEDIYIGNGVSELIVMAMQGLLNSGDEILVPSPDYPLWTAAVHLSGGKAQHYRCDEESDWFPDLED
IKSKITPRTRGIVLINPNNPTGAVYSKELILEVIELCRQNDMILFADEIYDKILYDEAEHIPAASLSDDILTVTFNGLSK
VYRAAGFRVGWMMLTGNLKAAKSYVEGLDMLASMRLCANVPSQHAIQTALGGYQSIHELVQPGGRLRVQRDACVEMLNSI
PGVSVKTPKGALYAFAKLDQKKFNLRDDERLVLDLLKDRKILLVQGSAFNYPEPDHVRVVFLPYKEELTKALSEFGDFLG
NYKQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=371, Percent_Identity=25.3369272237197, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI19263340, Length=473, Percent_Identity=24.7357293868922, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI215599424, Length=382, Percent_Identity=25.3926701570681, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI4885351, Length=443, Percent_Identity=24.6049661399549, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI95147551, Length=424, Percent_Identity=24.0566037735849, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI169881279, Length=424, Percent_Identity=24.0566037735849, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI56713256, Length=333, Percent_Identity=24.9249249249249, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI56713254, Length=333, Percent_Identity=24.9249249249249, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI169881281, Length=275, Percent_Identity=26.5454545454545, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI149944424, Length=390, Percent_Identity=23.8461538461538, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=69.5544554455445, Blast_Score=605, Evalue=1e-174,
Organism=Escherichia coli, GI1788722, Length=397, Percent_Identity=25.9445843828715, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786816, Length=330, Percent_Identity=23.6363636363636, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787909, Length=299, Percent_Identity=20.4013377926421, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=377, Percent_Identity=27.3209549071618, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71981209, Length=469, Percent_Identity=24.5202558635394, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71994472, Length=239, Percent_Identity=24.6861924686192, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71994476, Length=239, Percent_Identity=24.6861924686192, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17567369, Length=174, Percent_Identity=28.735632183908, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71981215, Length=294, Percent_Identity=23.469387755102, Blast_Score=78, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323118, Length=387, Percent_Identity=27.906976744186, Blast_Score=112, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6320317, Length=474, Percent_Identity=25.3164556962025, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6322401, Length=334, Percent_Identity=23.9520958083832, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI18859735, Length=381, Percent_Identity=24.4094488188976, Blast_Score=144, Evalue=9e-35,
Organism=Drosophila melanogaster, GI45551451, Length=476, Percent_Identity=24.7899159663866, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24641770, Length=476, Percent_Identity=24.7899159663866, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24641760, Length=476, Percent_Identity=24.7899159663866, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24641768, Length=476, Percent_Identity=24.7899159663866, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24641766, Length=476, Percent_Identity=24.7899159663866, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24641764, Length=476, Percent_Identity=24.7899159663866, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28573069, Length=327, Percent_Identity=25.3822629969419, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24646114, Length=327, Percent_Identity=25.3822629969419, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI28573067, Length=327, Percent_Identity=25.3822629969419, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI28573065, Length=327, Percent_Identity=25.3822629969419, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45156; Mature: 45156

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPIIKSNKLDSVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVIL
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPSAQGYCESKGLFSARKAIVQHYQSQGIFGVDIEDIYIGNGVSELIVMAMQGLLNSGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEECCHHEEEECCCHHHHHHHHHHHHHCCCC
EILVPSPDYPLWTAAVHLSGGKAQHYRCDEESDWFPDLEDIKSKITPRTRGIVLINPNNP
EEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCC
TGAVYSKELILEVIELCRQNDMILFADEIYDKILYDEAEHIPAASLSDDILTVTFNGLSK
CCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHH
VYRAAGFRVGWMMLTGNLKAAKSYVEGLDMLASMRLCANVPSQHAIQTALGGYQSIHELV
HHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHH
QPGGRLRVQRDACVEMLNSIPGVSVKTPKGALYAFAKLDQKKFNLRDDERLVLDLLKDRK
CCCCCEEECHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCE
ILLVQGSAFNYPEPDHVRVVFLPYKEELTKALSEFGDFLGNYKQ
EEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRPIIKSNKLDSVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVIL
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPSAQGYCESKGLFSARKAIVQHYQSQGIFGVDIEDIYIGNGVSELIVMAMQGLLNSGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEECCHHEEEECCCHHHHHHHHHHHHHCCCC
EILVPSPDYPLWTAAVHLSGGKAQHYRCDEESDWFPDLEDIKSKITPRTRGIVLINPNNP
EEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCC
TGAVYSKELILEVIELCRQNDMILFADEIYDKILYDEAEHIPAASLSDDILTVTFNGLSK
CCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHH
VYRAAGFRVGWMMLTGNLKAAKSYVEGLDMLASMRLCANVPSQHAIQTALGGYQSIHELV
HHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHH
QPGGRLRVQRDACVEMLNSIPGVSVKTPKGALYAFAKLDQKKFNLRDDERLVLDLLKDRK
CCCCCEEECHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCE
ILLVQGSAFNYPEPDHVRVVFLPYKEELTKALSEFGDFLGNYKQ
EEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]