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The map label for this gene is pgl [H]

Identifier: 167623880

GI number: 167623880

Start: 2344260

End: 2344964

Strand: Direct

Name: pgl [H]

Synonym: Shal_1950

Alternate gene names: 167623880

Gene position: 2344260-2344964 (Clockwise)

Preceding gene: 167623879

Following gene: 167623881

Centisome position: 44.85

GC content: 45.96

Gene sequence:

>705_bases
ATGATTAAAGAAACTGTTTTCAAATCATTTGACAATAAAGAAGCACTCGAAGCACAACTGGCGGAGCGTATTGCCAATCA
ACTGCAAGACGCCGTTGATGCCCGTGGTAAAGCGAGCCTTATTGTCTCAGGTGGCTCAACTCCGCTTAAGTTATTTGAAT
TGCTCAGTAAGAAAGGCATCGATTGGAGTGATGTTTACATCACACTCGCGGATGAGCGCTGGGTCAGTGCTGAGCATAGT
GATTCTAACGAGCGCCTAGTTCGAAATAATTTGCTAAAGAATAGAGCGGCTAATGCCAAATTTCGTGGCTTGAAGAACAT
GTATTCTTCGCCTGAAGAAGGTTGCGCCATGGCGATTGAACAACTTGGTAGTTTTCCTACACCATTCGATGTCGTCGTAT
TAGGCATGGGCAATGACGGCCATACCTGCTCTTGGTTCCCTTGCGCCGCAGAAGCTGAACTCGACAATGCATTAACGACA
ACCGACTTATGTGTTGCCGTTAAACCGGGTAATGCCCCGCATTCAAGGATTACTTTGTCGAAGTCAGCCATTTTAGCGAG
TCGTCAAATCTATTTACATATCGTTGGTGAGCAAAAATTAGATGTTTACCGACAAGCACTAGCAAGCGATGACTGTCGTG
AAATGCCTATCCGAGCGGTGCTCGGCCAGCATAAAACGCCTGTTGATGTTTACTGGAGCGCTTAA

Upstream 100 bases:

>100_bases
GAAAAGCCAAAGCCTTACCCTGCGGGTACATGGGGACCTGTGGCGTCTGTCGCGCTTATCACTAAAGATGGCCGTTCTTG
GGACGAGTAAGGTGAAACCG

Downstream 100 bases:

>100_bases
GGAGTAATTATGCACAGCGTTGTACAATCTGTTACCGACAGAATTATTGAACGAAGCAAAGATTCTCGCGCTAAATACTT
AGCGGCGCTCGATGATGCTA

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MIKETVFKSFDNKEALEAQLAERIANQLQDAVDARGKASLIVSGGSTPLKLFELLSKKGIDWSDVYITLADERWVSAEHS
DSNERLVRNNLLKNRAANAKFRGLKNMYSSPEEGCAMAIEQLGSFPTPFDVVVLGMGNDGHTCSWFPCAAEAELDNALTT
TDLCVAVKPGNAPHSRITLSKSAILASRQIYLHIVGEQKLDVYRQALASDDCREMPIRAVLGQHKTPVDVYWSA

Sequences:

>Translated_234_residues
MIKETVFKSFDNKEALEAQLAERIANQLQDAVDARGKASLIVSGGSTPLKLFELLSKKGIDWSDVYITLADERWVSAEHS
DSNERLVRNNLLKNRAANAKFRGLKNMYSSPEEGCAMAIEQLGSFPTPFDVVVLGMGNDGHTCSWFPCAAEAELDNALTT
TDLCVAVKPGNAPHSRITLSKSAILASRQIYLHIVGEQKLDVYRQALASDDCREMPIRAVLGQHKTPVDVYWSA
>Mature_234_residues
MIKETVFKSFDNKEALEAQLAERIANQLQDAVDARGKASLIVSGGSTPLKLFELLSKKGIDWSDVYITLADERWVSAEHS
DSNERLVRNNLLKNRAANAKFRGLKNMYSSPEEGCAMAIEQLGSFPTPFDVVVLGMGNDGHTCSWFPCAAEAELDNALTT
TDLCVAVKPGNAPHSRITLSKSAILASRQIYLHIVGEQKLDVYRQALASDDCREMPIRAVLGQHKTPVDVYWSA

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=219, Percent_Identity=26.9406392694064, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI115533060, Length=205, Percent_Identity=29.7560975609756, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI115533058, Length=205, Percent_Identity=29.7560975609756, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321957, Length=207, Percent_Identity=27.536231884058, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 25754; Mature: 25754

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKETVFKSFDNKEALEAQLAERIANQLQDAVDARGKASLIVSGGSTPLKLFELLSKKGI
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCC
DWSDVYITLADERWVSAEHSDSNERLVRNNLLKNRAANAKFRGLKNMYSSPEEGCAMAIE
CCCCEEEEEECCCEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHH
QLGSFPTPFDVVVLGMGNDGHTCSWFPCAAEAELDNALTTTDLCVAVKPGNAPHSRITLS
HHCCCCCCCCEEEEEECCCCCEEEEECCCCCCHHCCCEEEEEEEEEECCCCCCCCEEEEH
KSAILASRQIYLHIVGEQKLDVYRQALASDDCREMPIRAVLGQHKTPVDVYWSA
HHHHHHCCEEEEEEECCHHHHHHHHHHCCCCHHHCCHHHHHCCCCCCEEEEECC
>Mature Secondary Structure
MIKETVFKSFDNKEALEAQLAERIANQLQDAVDARGKASLIVSGGSTPLKLFELLSKKGI
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCC
DWSDVYITLADERWVSAEHSDSNERLVRNNLLKNRAANAKFRGLKNMYSSPEEGCAMAIE
CCCCEEEEEECCCEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHH
QLGSFPTPFDVVVLGMGNDGHTCSWFPCAAEAELDNALTTTDLCVAVKPGNAPHSRITLS
HHCCCCCCCCEEEEEECCCCCEEEEECCCCCCHHCCCEEEEEEEEEECCCCCCCCEEEEH
KSAILASRQIYLHIVGEQKLDVYRQALASDDCREMPIRAVLGQHKTPVDVYWSA
HHHHHHCCEEEEEEECCHHHHHHHHHHCCCCHHHCCHHHHHCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]