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The map label for this gene is fadE [H]

Identifier: 167623876

GI number: 167623876

Start: 2337252

End: 2339534

Strand: Direct

Name: fadE [H]

Synonym: Shal_1946

Alternate gene names: 167623876

Gene position: 2337252-2339534 (Clockwise)

Preceding gene: 167623875

Following gene: 167623879

Centisome position: 44.72

GC content: 46.17

Gene sequence:

>2283_bases
ATGGCTACGACATTATTAATACTATTGATTGGCACAATAGTGGTTGTATTCAGTGTTAAAAATATCAGGATGCAACTCGT
TACCCGCCCTGTATTTAGCTTTTTTAAAAAAGTGCTACCTCCGCTTTCCAAAACTGAAAAAGAAGCGATGGAAGCGGGCG
ACGTTTGGTGGGAAGGGGAGCTCTTTAAGGGGAAACCCAATTGGCAAGTGCTCCACAGTTACGGTAAACCGTCTTTGACC
TCAGAAGAGCAGGACTTTATCGACAATCAAGTGGTAACCGCATTAACCATGATTGACGATTACAACATCGTTAATGAGAG
AAAAGATCTGCCACCAGAGCTATGGGACTACTTCAAAAAAGAGGGCTTCTTTGCGCTTATCATACCTAAAAAGTACGGTG
GTAAGGCATTCTCAGCGTACGCTAACTCTACCATTGTCAGCAAAATTGCCAGTCGTAGCGTAAGTGCGGCTGTAACCGTT
ATGGTGCCGAACTCACTTGGTCCTGGTGAGTTACTCACTCACTACGGAACCAGCGAACAGAAAGACTTTTGGTTACCACA
ACTGGCCGATGGAAGTGCTATTCCTTGCTTTGCATTAACAGGCCTAGAGGCGGGGAGCGACGCGGGGGCCATTCCGGATT
CCGGTGTTGTTTGTCGTCAAGAGTTTAATGGCGAAGAAACACTCGGCTTAAAGCTTAACTGGGATAAGCGTTATATTACC
CTTGCACCAGTGGCCAATGTACTCGGTCTCGCGTTTCAAATGTATGACCCAGACGGTCTGCTTGGTGATACTCAGCAGAT
AGGTATTACCTGTGCGCTGATCCCAACGGATCACAATGGGGTTGAAATCGGTCGTCGCCATAACCCGTTAAATATGGCGT
TTATGAACGGTACTACTCGAGGACAAGATGTCTTTATTCCGTTAGATTGGATTATTGGTGGCCCCCAGTTCGCGGGACGT
GGCTGGAGAATGTTAGTCGAGTGTCTTTCTGCGGGGCGTGGTATTTCACTTCCAGCACTATCGACGGCATCGGGTCATAT
GGCGACTAAGACCACAACCGCATACAGCGCAGTGCGTCAACAGTTTGGTTTAGATATTGGTAAATTCGAAGGTGTACAAG
AGGCCTTAGCACGGGTTATTGCTAATACTTACCAGCTTGAAGCTGCAAGGCGTTTAACCACAACTGGCATCGATTTAAAA
GTCAAACCGTCAGTGGTAACCGCGATCGCTAAATACCATATGACCGAACTTGGACGTAAGGTCATAGATGATGCGATGGA
CATTCAGTCTGGTAAAGGGATCCAACTTGGACCTAAGAATTATTTGGGCCACGGTTATATGGCGCTACCCATCTCTATTA
CGGTAGAAGGGGCCAATATTTTAACCAGAAGCTTGATGATCTTCGGTCAAGGTGCCACGCGCTGTCATCCATACGTGTTA
GCAGAGATGGAAGCGGCAGGTATGGAAGATACCAACGAAGGGTTAGAGCGTTTTGATGACTTACTATTAGGCCATATCGG
TTATGCGACGCGTAATGCTTTCAGCGCGTTCGGTAATGCGGTCACTGGCAGTCACTTTTCACAATCTCCAGTGAGTGGTG
AAACTAAGCAGTATTATAAAGACATGAATCGTTTGTCTGCAGCTCTTGCCTTGATGACAGATGTTTCTATGCTTATTCTA
GGTGGTGAGCTGAAACGTAAAGAGATGCTTAGTGCCCGTATGGGGGACGTGTTAAGTCAACTATACCTAGGCTCTGCAAC
CTTAAAGTTATTTGAAGATAACGGTCGTCAATTTGATGATTTACCCGCGGTTCGTCATGTTATGGCTACACGTCTGCATT
TGGCGGCAAAAGCGTTAGATGAAGCCATTCGTAACTTCCCTAATCGCGGCGTTGCTTTACTAATGCGTGCATTAATCTTC
CCGCTTGGAAACCGCTTTAAAGAGGCGAGCGATAAGCTTTCAATCGACCTGGTTAATTCGATGAGTAAGCCTTGTCCTGC
ACGAGATAGATTAACCTTCTTGTGTCCTGATTTTAAAGGAGATACCGGCGGTATCGCTGAAGTTGAGAATGCATTTATTG
CAAAGCATGCCTGTAACGGCCTGTATAAAAAGCTTAAGCAAGCACAAAGGGAGGGGAGTTTACCAACTAAACTTCAGCCT
TTGGCCTTGTTTGACTCGGCTCTAGAGATCTCGCTGATAACTCAAGAGGAGCATCAACAGTTAGTTCAGGCTGACGCGTT
ACGCTTAGCGGCTATCAATGTAGATGAGTTTGAAAGCCTGTAA

Upstream 100 bases:

>100_bases
TTGGGGAGCACAATGATATAGAAGCTGTTATTAGAAAAGTCATTCCGTATTTATCTGCCGGGGTATCGGTCCCACTTACT
AAGGATGTAATGTAAAAATT

Downstream 100 bases:

>100_bases
TATGGAACAATTAAAGAGCGAATACCTTTTGGTTTAGCTCTTTATACCAATCAGTATAAGAAGTTGATCTACTCAGAACG
TTTTTGGCAAACTAATTAAA

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: ACDH [H]

Number of amino acids: Translated: 760; Mature: 759

Protein sequence:

>760_residues
MATTLLILLIGTIVVVFSVKNIRMQLVTRPVFSFFKKVLPPLSKTEKEAMEAGDVWWEGELFKGKPNWQVLHSYGKPSLT
SEEQDFIDNQVVTALTMIDDYNIVNERKDLPPELWDYFKKEGFFALIIPKKYGGKAFSAYANSTIVSKIASRSVSAAVTV
MVPNSLGPGELLTHYGTSEQKDFWLPQLADGSAIPCFALTGLEAGSDAGAIPDSGVVCRQEFNGEETLGLKLNWDKRYIT
LAPVANVLGLAFQMYDPDGLLGDTQQIGITCALIPTDHNGVEIGRRHNPLNMAFMNGTTRGQDVFIPLDWIIGGPQFAGR
GWRMLVECLSAGRGISLPALSTASGHMATKTTTAYSAVRQQFGLDIGKFEGVQEALARVIANTYQLEAARRLTTTGIDLK
VKPSVVTAIAKYHMTELGRKVIDDAMDIQSGKGIQLGPKNYLGHGYMALPISITVEGANILTRSLMIFGQGATRCHPYVL
AEMEAAGMEDTNEGLERFDDLLLGHIGYATRNAFSAFGNAVTGSHFSQSPVSGETKQYYKDMNRLSAALALMTDVSMLIL
GGELKRKEMLSARMGDVLSQLYLGSATLKLFEDNGRQFDDLPAVRHVMATRLHLAAKALDEAIRNFPNRGVALLMRALIF
PLGNRFKEASDKLSIDLVNSMSKPCPARDRLTFLCPDFKGDTGGIAEVENAFIAKHACNGLYKKLKQAQREGSLPTKLQP
LALFDSALEISLITQEEHQQLVQADALRLAAINVDEFESL

Sequences:

>Translated_760_residues
MATTLLILLIGTIVVVFSVKNIRMQLVTRPVFSFFKKVLPPLSKTEKEAMEAGDVWWEGELFKGKPNWQVLHSYGKPSLT
SEEQDFIDNQVVTALTMIDDYNIVNERKDLPPELWDYFKKEGFFALIIPKKYGGKAFSAYANSTIVSKIASRSVSAAVTV
MVPNSLGPGELLTHYGTSEQKDFWLPQLADGSAIPCFALTGLEAGSDAGAIPDSGVVCRQEFNGEETLGLKLNWDKRYIT
LAPVANVLGLAFQMYDPDGLLGDTQQIGITCALIPTDHNGVEIGRRHNPLNMAFMNGTTRGQDVFIPLDWIIGGPQFAGR
GWRMLVECLSAGRGISLPALSTASGHMATKTTTAYSAVRQQFGLDIGKFEGVQEALARVIANTYQLEAARRLTTTGIDLK
VKPSVVTAIAKYHMTELGRKVIDDAMDIQSGKGIQLGPKNYLGHGYMALPISITVEGANILTRSLMIFGQGATRCHPYVL
AEMEAAGMEDTNEGLERFDDLLLGHIGYATRNAFSAFGNAVTGSHFSQSPVSGETKQYYKDMNRLSAALALMTDVSMLIL
GGELKRKEMLSARMGDVLSQLYLGSATLKLFEDNGRQFDDLPAVRHVMATRLHLAAKALDEAIRNFPNRGVALLMRALIF
PLGNRFKEASDKLSIDLVNSMSKPCPARDRLTFLCPDFKGDTGGIAEVENAFIAKHACNGLYKKLKQAQREGSLPTKLQP
LALFDSALEISLITQEEHQQLVQADALRLAAINVDEFESL
>Mature_759_residues
ATTLLILLIGTIVVVFSVKNIRMQLVTRPVFSFFKKVLPPLSKTEKEAMEAGDVWWEGELFKGKPNWQVLHSYGKPSLTS
EEQDFIDNQVVTALTMIDDYNIVNERKDLPPELWDYFKKEGFFALIIPKKYGGKAFSAYANSTIVSKIASRSVSAAVTVM
VPNSLGPGELLTHYGTSEQKDFWLPQLADGSAIPCFALTGLEAGSDAGAIPDSGVVCRQEFNGEETLGLKLNWDKRYITL
APVANVLGLAFQMYDPDGLLGDTQQIGITCALIPTDHNGVEIGRRHNPLNMAFMNGTTRGQDVFIPLDWIIGGPQFAGRG
WRMLVECLSAGRGISLPALSTASGHMATKTTTAYSAVRQQFGLDIGKFEGVQEALARVIANTYQLEAARRLTTTGIDLKV
KPSVVTAIAKYHMTELGRKVIDDAMDIQSGKGIQLGPKNYLGHGYMALPISITVEGANILTRSLMIFGQGATRCHPYVLA
EMEAAGMEDTNEGLERFDDLLLGHIGYATRNAFSAFGNAVTGSHFSQSPVSGETKQYYKDMNRLSAALALMTDVSMLILG
GELKRKEMLSARMGDVLSQLYLGSATLKLFEDNGRQFDDLPAVRHVMATRLHLAAKALDEAIRNFPNRGVALLMRALIFP
LGNRFKEASDKLSIDLVNSMSKPCPARDRLTFLCPDFKGDTGGIAEVENAFIAKHACNGLYKKLKQAQREGSLPTKLQPL
ALFDSALEISLITQEEHQQLVQADALRLAAINVDEFESL

Specific function: Catalyzes the dehydrogenation of acyl-CoA [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=383, Percent_Identity=27.154046997389, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI4557235, Length=409, Percent_Identity=25.4278728606357, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI76496475, Length=388, Percent_Identity=25.7731958762887, Blast_Score=90, Evalue=9e-18,
Organism=Homo sapiens, GI4557233, Length=382, Percent_Identity=28.2722513089005, Blast_Score=90, Evalue=9e-18,
Organism=Homo sapiens, GI4501859, Length=360, Percent_Identity=27.7777777777778, Blast_Score=87, Evalue=6e-17,
Organism=Escherichia coli, GI87081702, Length=759, Percent_Identity=51.6469038208169, Blast_Score=781, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985184, Length=437, Percent_Identity=25.629290617849, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17508101, Length=283, Percent_Identity=29.6819787985866, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71985192, Length=349, Percent_Identity=25.214899713467, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17570075, Length=331, Percent_Identity=27.4924471299094, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356377, Length=359, Percent_Identity=27.2980501392758, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281363737, Length=355, Percent_Identity=25.3521126760563, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24646207, Length=337, Percent_Identity=26.4094955489614, Blast_Score=77, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100
- InterPro:   IPR015396 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N; PF09317 DUF1974 [H]

EC number: NA

Molecular weight: Translated: 83192; Mature: 83061

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTLLILLIGTIVVVFSVKNIRMQLVTRPVFSFFKKVLPPLSKTEKEAMEAGDVWWEGE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEECCE
LFKGKPNWQVLHSYGKPSLTSEEQDFIDNQVVTALTMIDDYNIVNERKDLPPELWDYFKK
EECCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHH
EGFFALIIPKKYGGKAFSAYANSTIVSKIASRSVSAAVTVMVPNSLGPGELLTHYGTSEQ
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHCCCCCC
KDFWLPQLADGSAIPCFALTGLEAGSDAGAIPDSGVVCRQEFNGEETLGLKLNWDKRYIT
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEHHCCCCCCEEEEEEECCCCEEE
LAPVANVLGLAFQMYDPDGLLGDTQQIGITCALIPTDHNGVEIGRRHNPLNMAFMNGTTR
HHHHHHHHHHHHEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCC
GQDVFIPLDWIIGGPQFAGRGWRMLVECLSAGRGISLPALSTASGHMATKTTTAYSAVRQ
CCEEEEEHHEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHHHHHHHHH
QFGLDIGKFEGVQEALARVIANTYQLEAARRLTTTGIDLKVKPSVVTAIAKYHMTELGRK
HHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHEECCCCEEECHHHHHHHHHHHHHHHHHH
VIDDAMDIQSGKGIQLGPKNYLGHGYMALPISITVEGANILTRSLMIFGQGATRCHPYVL
HHHHHHHCCCCCCCEECCCCCCCCCEEEEEEEEEEECHHHHHHHHHEECCCCCCCCCEEE
AEMEAAGMEDTNEGLERFDDLLLGHIGYATRNAFSAFGNAVTGSHFSQSPVSGETKQYYK
EEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
DMNRLSAALALMTDVSMLILGGELKRKEMLSARMGDVLSQLYLGSATLKLFEDNGRQFDD
HHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHH
LPAVRHVMATRLHLAAKALDEAIRNFPNRGVALLMRALIFPLGNRFKEASDKLSIDLVNS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHCCCEEHHHHHH
MSKPCPARDRLTFLCPDFKGDTGGIAEVENAFIAKHACNGLYKKLKQAQREGSLPTKLQP
CCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
LALFDSALEISLITQEEHQQLVQADALRLAAINVDEFESL
HHHHCCCEEEEEECHHHHHHHHHHHHHHEEEECHHHHHCC
>Mature Secondary Structure 
ATTLLILLIGTIVVVFSVKNIRMQLVTRPVFSFFKKVLPPLSKTEKEAMEAGDVWWEGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEECCE
LFKGKPNWQVLHSYGKPSLTSEEQDFIDNQVVTALTMIDDYNIVNERKDLPPELWDYFKK
EECCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHH
EGFFALIIPKKYGGKAFSAYANSTIVSKIASRSVSAAVTVMVPNSLGPGELLTHYGTSEQ
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHCCCCCC
KDFWLPQLADGSAIPCFALTGLEAGSDAGAIPDSGVVCRQEFNGEETLGLKLNWDKRYIT
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEHHCCCCCCEEEEEEECCCCEEE
LAPVANVLGLAFQMYDPDGLLGDTQQIGITCALIPTDHNGVEIGRRHNPLNMAFMNGTTR
HHHHHHHHHHHHEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCC
GQDVFIPLDWIIGGPQFAGRGWRMLVECLSAGRGISLPALSTASGHMATKTTTAYSAVRQ
CCEEEEEHHEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHHHHHHHHH
QFGLDIGKFEGVQEALARVIANTYQLEAARRLTTTGIDLKVKPSVVTAIAKYHMTELGRK
HHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHEECCCCEEECHHHHHHHHHHHHHHHHHH
VIDDAMDIQSGKGIQLGPKNYLGHGYMALPISITVEGANILTRSLMIFGQGATRCHPYVL
HHHHHHHCCCCCCCEECCCCCCCCCEEEEEEEEEEECHHHHHHHHHEECCCCCCCCCEEE
AEMEAAGMEDTNEGLERFDDLLLGHIGYATRNAFSAFGNAVTGSHFSQSPVSGETKQYYK
EEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
DMNRLSAALALMTDVSMLILGGELKRKEMLSARMGDVLSQLYLGSATLKLFEDNGRQFDD
HHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHH
LPAVRHVMATRLHLAAKALDEAIRNFPNRGVALLMRALIFPLGNRFKEASDKLSIDLVNS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHCCCEEHHHHHH
MSKPCPARDRLTFLCPDFKGDTGGIAEVENAFIAKHACNGLYKKLKQAQREGSLPTKLQP
CCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
LALFDSALEISLITQEEHQQLVQADALRLAAINVDEFESL
HHHHCCCEEEEEECHHHHHHHHHHHHHHEEEECHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]