Click here to switch to the map view.

The map label for this gene is atsA [H]

Identifier: 167623816

GI number: 167623816

Start: 2264544

End: 2266208

Strand: Direct

Name: atsA [H]

Synonym: Shal_1886

Alternate gene names: 167623816

Gene position: 2264544-2266208 (Clockwise)

Preceding gene: 167623814

Following gene: 167623817

Centisome position: 43.32

GC content: 44.38

Gene sequence:

>1665_bases
ATGAAACTCAACAAAATCATGTTAACGCTGTTGTCCGTATGTACTATCGCGTCAAATCCAATGATGGCGTACGCGAAAGA
TCACAACGAGACTATCGACGCTCAAGAACCCCCCAATATTATCCTCATTGTTGCAGATGACTTAGGTTGGACCGACTTAA
GTCGTTATGGCAGCGAAATACAGACACCAAATATTGATCTGATAGCCCATGAAGGTATTCAGTTTACCGACTTTCATGCA
TCAGTAAGCTGCTCACCGACCCGCACCATGTTGCTAACTGGCGTGGATAACCATCAAGCGGGTATGGGAAATATGAGTGA
GCTATTGACCGAGGCCCAAAGGGGACAGCCTGGCTACGAAGGCTATATAAACAAAGATGTTGTCACTTTGTCTGAGGTAT
TAAAGAACAACAATTATAACACTTACATGGCAGGTAAATGGCATTTGGGTCATCAGCAAACAAACTGGCCGTATGCGCGT
GGGTTTGAACGCTCATTTAGCACACTTGAAGCCGGGGGGAGTCATTGGTCTGATATGACAGGTTTGTTGGCTGAAATACA
GGAAACATCGACGTATGTTCGTGACAACAAGCAATTAACTGAGCTACCAAGAAGTTTTTATTCCACAACGGCCTATACCG
ATGAGTTAATGACCTATATCCGAGAAGGTAAGCGCAATAACAAGCCCTTCTTTGGATACTTGGCATTTACAGCACCACAT
GATCCTTTGCACGCGCCTGAACCTTGGTTGAGTGAGTATGAAGGGGTTTATGATTCAGGATATGAAGTATTAAAAGCGCA
GCGTATCAAAAATAGTAAAAAGCTTGGGCTAATTAGTCAGGACGCCCCAGAGCCAGAGATGCACCCCGTTGTTACGCCAT
GGAAGCAGCTCTCCAAAGAGCAAAAAATGATAGAAACTAAAGCGATGGAAACATACGCTGGCATGATCTCCAACATGGAC
TACAACGTTGGCCGATTACAGCGTTTTCTGAAAGACATCAATGAATATGATAATACCATTTTTGTTTTCATGAGTGATAA
CGGCGCTAACCCATGGTTCTCAGAAGAGTATCCGGGGAACAGAGGCAGTTCATTTTTAGCTCAGTTTGACAATAGCTTAG
AAAATATTGGCCAACCGATGTCACATTATGCCTATGGCGCGGGATGGGCTTCTGCAAGCAACGGTCCTTTGGACCGCTTT
AAAATGACTGTCAGTGAGGGAGGCATTAGAGTTCCCTTGCTGATCTCTGGCCCAGGCATAAACAAGCGCGATGATATTAA
CGGTAGTTTCGCTTATGTGACTGATCTTATGCCAACGCTGCTCGATTATGCCAATGCAAAACATCCTGACACCTTTAATG
GGCGTGATGTGATAGATATGCAGGGTAAATCAATGCGCCAAATGCTTGAGGGGAAAAAAGAGTCGGTTCATAGCGACAGT
GATGTCACCAGTGGCGAAATGAGGTTTGGCAGATGGACGAGATTAGGAGACTTTAAAGCCGCGATGATCCCAAAGCCATA
CGGTGATGGTCAATGGAAATTGTTTAATCTTGTAAACGATCCAGGAGAAACGAACGATCTATCCAAACAGTATCCACAAA
AACTGCAGCAACTTACGCAAGAATGGGATAAGTATGCGGAGCGTGTTGGTGTTATTGGAAAATAA

Upstream 100 bases:

>100_bases
AATCTCTCTTTCCATATGTTCAAGTGTTCCTTTCCTAATAGTCCAAATATTCAAGGTAACATAACTTAGCCCATTCTAAA
ATAAGATAGAAATTCAGGTT

Downstream 100 bases:

>100_bases
TAAATAATGATTAAGGGCAAGGATGCCCAACTATTCTTGAGGTTCTGATGCAGCATTTGAATAAAGCAATGAAAAAGCTA
CACGTGATGGTTAAGCCTGT

Product: sulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MKLNKIMLTLLSVCTIASNPMMAYAKDHNETIDAQEPPNIILIVADDLGWTDLSRYGSEIQTPNIDLIAHEGIQFTDFHA
SVSCSPTRTMLLTGVDNHQAGMGNMSELLTEAQRGQPGYEGYINKDVVTLSEVLKNNNYNTYMAGKWHLGHQQTNWPYAR
GFERSFSTLEAGGSHWSDMTGLLAEIQETSTYVRDNKQLTELPRSFYSTTAYTDELMTYIREGKRNNKPFFGYLAFTAPH
DPLHAPEPWLSEYEGVYDSGYEVLKAQRIKNSKKLGLISQDAPEPEMHPVVTPWKQLSKEQKMIETKAMETYAGMISNMD
YNVGRLQRFLKDINEYDNTIFVFMSDNGANPWFSEEYPGNRGSSFLAQFDNSLENIGQPMSHYAYGAGWASASNGPLDRF
KMTVSEGGIRVPLLISGPGINKRDDINGSFAYVTDLMPTLLDYANAKHPDTFNGRDVIDMQGKSMRQMLEGKKESVHSDS
DVTSGEMRFGRWTRLGDFKAAMIPKPYGDGQWKLFNLVNDPGETNDLSKQYPQKLQQLTQEWDKYAERVGVIGK

Sequences:

>Translated_554_residues
MKLNKIMLTLLSVCTIASNPMMAYAKDHNETIDAQEPPNIILIVADDLGWTDLSRYGSEIQTPNIDLIAHEGIQFTDFHA
SVSCSPTRTMLLTGVDNHQAGMGNMSELLTEAQRGQPGYEGYINKDVVTLSEVLKNNNYNTYMAGKWHLGHQQTNWPYAR
GFERSFSTLEAGGSHWSDMTGLLAEIQETSTYVRDNKQLTELPRSFYSTTAYTDELMTYIREGKRNNKPFFGYLAFTAPH
DPLHAPEPWLSEYEGVYDSGYEVLKAQRIKNSKKLGLISQDAPEPEMHPVVTPWKQLSKEQKMIETKAMETYAGMISNMD
YNVGRLQRFLKDINEYDNTIFVFMSDNGANPWFSEEYPGNRGSSFLAQFDNSLENIGQPMSHYAYGAGWASASNGPLDRF
KMTVSEGGIRVPLLISGPGINKRDDINGSFAYVTDLMPTLLDYANAKHPDTFNGRDVIDMQGKSMRQMLEGKKESVHSDS
DVTSGEMRFGRWTRLGDFKAAMIPKPYGDGQWKLFNLVNDPGETNDLSKQYPQKLQQLTQEWDKYAERVGVIGK
>Mature_554_residues
MKLNKIMLTLLSVCTIASNPMMAYAKDHNETIDAQEPPNIILIVADDLGWTDLSRYGSEIQTPNIDLIAHEGIQFTDFHA
SVSCSPTRTMLLTGVDNHQAGMGNMSELLTEAQRGQPGYEGYINKDVVTLSEVLKNNNYNTYMAGKWHLGHQQTNWPYAR
GFERSFSTLEAGGSHWSDMTGLLAEIQETSTYVRDNKQLTELPRSFYSTTAYTDELMTYIREGKRNNKPFFGYLAFTAPH
DPLHAPEPWLSEYEGVYDSGYEVLKAQRIKNSKKLGLISQDAPEPEMHPVVTPWKQLSKEQKMIETKAMETYAGMISNMD
YNVGRLQRFLKDINEYDNTIFVFMSDNGANPWFSEEYPGNRGSSFLAQFDNSLENIGQPMSHYAYGAGWASASNGPLDRF
KMTVSEGGIRVPLLISGPGINKRDDINGSFAYVTDLMPTLLDYANAKHPDTFNGRDVIDMQGKSMRQMLEGKKESVHSDS
DVTSGEMRFGRWTRLGDFKAAMIPKPYGDGQWKLFNLVNDPGETNDLSKQYPQKLQQLTQEWDKYAERVGVIGK

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI38569405, Length=560, Percent_Identity=23.9285714285714, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI38569407, Length=417, Percent_Identity=25.4196642685851, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI109389362, Length=546, Percent_Identity=23.6263736263736, Blast_Score=136, Evalue=6e-32,
Organism=Homo sapiens, GI59797060, Length=548, Percent_Identity=23.7226277372263, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI146229331, Length=442, Percent_Identity=28.5067873303167, Blast_Score=109, Evalue=9e-24,
Organism=Homo sapiens, GI146229329, Length=442, Percent_Identity=28.5067873303167, Blast_Score=109, Evalue=9e-24,
Organism=Homo sapiens, GI6005990, Length=442, Percent_Identity=28.5067873303167, Blast_Score=109, Evalue=9e-24,
Organism=Homo sapiens, GI146229324, Length=442, Percent_Identity=28.5067873303167, Blast_Score=109, Evalue=9e-24,
Organism=Homo sapiens, GI45430057, Length=493, Percent_Identity=26.1663286004057, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4503899, Length=224, Percent_Identity=31.6964285714286, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI53831991, Length=459, Percent_Identity=25.2723311546841, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI58743319, Length=334, Percent_Identity=24.5508982035928, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI157266309, Length=313, Percent_Identity=26.1980830670927, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI31742482, Length=466, Percent_Identity=24.2489270386266, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI71852586, Length=120, Percent_Identity=36.6666666666667, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI71852584, Length=120, Percent_Identity=36.6666666666667, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1790233, Length=183, Percent_Identity=29.5081967213115, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790112, Length=505, Percent_Identity=22.3762376237624, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI115533416, Length=533, Percent_Identity=24.765478424015, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI115533418, Length=523, Percent_Identity=24.4741873804971, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17559078, Length=238, Percent_Identity=27.3109243697479, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281363223, Length=479, Percent_Identity=27.348643006263, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24666109, Length=414, Percent_Identity=26.5700483091787, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24666175, Length=475, Percent_Identity=25.2631578947368, Blast_Score=116, Evalue=5e-26,
Organism=Drosophila melanogaster, GI281366397, Length=294, Percent_Identity=29.5918367346939, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281366395, Length=294, Percent_Identity=29.5918367346939, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24666163, Length=294, Percent_Identity=29.5918367346939, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24653364, Length=451, Percent_Identity=25.2771618625277, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI19922168, Length=445, Percent_Identity=24.7191011235955, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 62522; Mature: 62522

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNKIMLTLLSVCTIASNPMMAYAKDHNETIDAQEPPNIILIVADDLGWTDLSRYGSEI
CCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHCCCC
QTPNIDLIAHEGIQFTDFHASVSCSPTRTMLLTGVDNHQAGMGNMSELLTEAQRGQPGYE
CCCCEEEEEECCCEEEECCCEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCC
GYINKDVVTLSEVLKNNNYNTYMAGKWHLGHQQTNWPYARGFERSFSTLEAGGSHWSDMT
CCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHH
GLLAEIQETSTYVRDNKQLTELPRSFYSTTAYTDELMTYIREGKRNNKPFFGYLAFTAPH
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCC
DPLHAPEPWLSEYEGVYDSGYEVLKAQRIKNSKKLGLISQDAPEPEMHPVVTPWKQLSKE
CCCCCCCHHHHHHCCHHHCCHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCHHHHHHH
QKMIETKAMETYAGMISNMDYNVGRLQRFLKDINEYDNTIFVFMSDNGANPWFSEEYPGN
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCC
RGSSFLAQFDNSLENIGQPMSHYAYGAGWASASNGPLDRFKMTVSEGGIRVPLLISGPGI
CCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCHHHEEEEECCCCEEEEEEEECCCC
NKRDDINGSFAYVTDLMPTLLDYANAKHPDTFNGRDVIDMQGKSMRQMLEGKKESVHSDS
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHCCHHHHCCCCC
DVTSGEMRFGRWTRLGDFKAAMIPKPYGDGQWKLFNLVNDPGETNDLSKQYPQKLQQLTQ
CCCCCCCCCCCCCCCCCCCCEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHH
EWDKYAERVGVIGK
HHHHHHHHHCCCCC
>Mature Secondary Structure
MKLNKIMLTLLSVCTIASNPMMAYAKDHNETIDAQEPPNIILIVADDLGWTDLSRYGSEI
CCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHCCCC
QTPNIDLIAHEGIQFTDFHASVSCSPTRTMLLTGVDNHQAGMGNMSELLTEAQRGQPGYE
CCCCEEEEEECCCEEEECCCEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCC
GYINKDVVTLSEVLKNNNYNTYMAGKWHLGHQQTNWPYARGFERSFSTLEAGGSHWSDMT
CCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHH
GLLAEIQETSTYVRDNKQLTELPRSFYSTTAYTDELMTYIREGKRNNKPFFGYLAFTAPH
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCC
DPLHAPEPWLSEYEGVYDSGYEVLKAQRIKNSKKLGLISQDAPEPEMHPVVTPWKQLSKE
CCCCCCCHHHHHHCCHHHCCHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCHHHHHHH
QKMIETKAMETYAGMISNMDYNVGRLQRFLKDINEYDNTIFVFMSDNGANPWFSEEYPGN
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCC
RGSSFLAQFDNSLENIGQPMSHYAYGAGWASASNGPLDRFKMTVSEGGIRVPLLISGPGI
CCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCHHHEEEEECCCCEEEEEEEECCCC
NKRDDINGSFAYVTDLMPTLLDYANAKHPDTFNGRDVIDMQGKSMRQMLEGKKESVHSDS
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHCCHHHHCCCCC
DVTSGEMRFGRWTRLGDFKAAMIPKPYGDGQWKLFNLVNDPGETNDLSKQYPQKLQQLTQ
CCCCCCCCCCCCCCCCCCCCEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHH
EWDKYAERVGVIGK
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]