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The map label for this gene is chuR [H]

Identifier: 167623817

GI number: 167623817

Start: 2266256

End: 2267500

Strand: Direct

Name: chuR [H]

Synonym: Shal_1887

Alternate gene names: 167623817

Gene position: 2266256-2267500 (Clockwise)

Preceding gene: 167623816

Following gene: 167623818

Centisome position: 43.36

GC content: 42.41

Gene sequence:

>1245_bases
ATGCAGCATTTGAATAAAGCAATGAAAAAGCTACACGTGATGGTTAAGCCTGTTGGCGCAGCATGCAATTTAGATTGCAC
GTACTGTTATTACTTAAGTAAAAGCGATCTGCTTGACTATCGAGGGGAGTTTAAAATGAACTACGCCTCGTTAGAGCAGT
TCATTAAGCAATACATACAAGCACACAATGCGCCTGAGATATTGTTTACCTGGCAAGGCGGTGAGCCCACATTACTCGGC
ATTGATTACTTCAAAAAAGTTGTAGAGCTGCAACAAAAATATTGCCCGCAAGGTAGCGTAATACTCAATGACTTGCAGAC
CAATGGCGTATTGCTTAATGATAAATGGTGTCAGTTTCTTAAAGAAAATCGATTTATTGTGGGATTGAGCATTGATGGGC
CAAAAGCAATACATGACTATTATCGGGTGAATAAAGCAGGTAAGGGCAGTTTTGAACAAGTCTATCGCTCAGTATTGTTG
CTGCAAAAACATCAAGTGCCCTTTGCGACTCTGACATGTATTAATAACCACTCGGCGCAATATGCACTAGAGATTTATCA
GTTTCTGCGAGATGTGTTGCAATCGCCGCAGATCCAGTTTATCCCTATCGTAGAGCACAGCAGCTTTACAGCTGAATCTT
CGACACAAGCACTCATCGATGTGAAGGTGGTGGGGGCTAATGCCGCGACCAATGTGACCTCTTGGTCCGTCTCTGCGCAG
CAGTGGGGGCAGTTCCTCTGCACCGTCTTTGACGAATGGTACGAAAATGATATCGGTAAAGAGAATGTCATCTATTTTGA
AGCCATGTTCCAGATATGGCTCGGGATGACGTCACCAATATGTACTCATGCCCCTTTGTGTGGCAAGGGATTAGCAATGG
AGCTTAATGGTGATGTCTATAGTTGTGATCACTTTGTCTACCCAGATTATAAGCTGGGAAATATAAACGATCATCAATTA
GATGAGATGGCTTTTTCCAAAAAACAGGAAGATTTTGGTAGAGGAAAATCCACAACACTGACGCCACAGTGTCAGCGCTG
TGACTATTTGTTTGCCTGTTATGGCGAATGCCCTAAAAACAGAATTGCCACCGATAAAGCGGGTAACATAGGACATAATT
TCTTATGTCAGGGCTGGTATATGTTTTACAGTTATATTGATGAACGCTTAGCAAAGCTTATCAAAAGTAAGGGGTTATCT
GTATCCAAAGGAGCCTATAAAGCAAAACTAGCAAAGGTGCGCTAA

Upstream 100 bases:

>100_bases
TTACGCAAGAATGGGATAAGTATGCGGAGCGTGTTGGTGTTATTGGAAAATAATAAATAATGATTAAGGGCAAGGATGCC
CAACTATTCTTGAGGTTCTG

Downstream 100 bases:

>100_bases
CAGCACCTCTAGTGCAGTTAGCAGCTTTATCTGCTTCTAAGCTCCATTAAAAATGAGCTGATGTCTTAGTCTTACATTAA
GTGTGTCAGGTAACTGATAA

Product: radical SAM domain-containing protein

Products: NA

Alternate protein names: AnSME; Chondroitin sulfate/heparin utilization regulation protein; Ser-type sulfatase-activating enzyme [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MQHLNKAMKKLHVMVKPVGAACNLDCTYCYYLSKSDLLDYRGEFKMNYASLEQFIKQYIQAHNAPEILFTWQGGEPTLLG
IDYFKKVVELQQKYCPQGSVILNDLQTNGVLLNDKWCQFLKENRFIVGLSIDGPKAIHDYYRVNKAGKGSFEQVYRSVLL
LQKHQVPFATLTCINNHSAQYALEIYQFLRDVLQSPQIQFIPIVEHSSFTAESSTQALIDVKVVGANAATNVTSWSVSAQ
QWGQFLCTVFDEWYENDIGKENVIYFEAMFQIWLGMTSPICTHAPLCGKGLAMELNGDVYSCDHFVYPDYKLGNINDHQL
DEMAFSKKQEDFGRGKSTTLTPQCQRCDYLFACYGECPKNRIATDKAGNIGHNFLCQGWYMFYSYIDERLAKLIKSKGLS
VSKGAYKAKLAKVR

Sequences:

>Translated_414_residues
MQHLNKAMKKLHVMVKPVGAACNLDCTYCYYLSKSDLLDYRGEFKMNYASLEQFIKQYIQAHNAPEILFTWQGGEPTLLG
IDYFKKVVELQQKYCPQGSVILNDLQTNGVLLNDKWCQFLKENRFIVGLSIDGPKAIHDYYRVNKAGKGSFEQVYRSVLL
LQKHQVPFATLTCINNHSAQYALEIYQFLRDVLQSPQIQFIPIVEHSSFTAESSTQALIDVKVVGANAATNVTSWSVSAQ
QWGQFLCTVFDEWYENDIGKENVIYFEAMFQIWLGMTSPICTHAPLCGKGLAMELNGDVYSCDHFVYPDYKLGNINDHQL
DEMAFSKKQEDFGRGKSTTLTPQCQRCDYLFACYGECPKNRIATDKAGNIGHNFLCQGWYMFYSYIDERLAKLIKSKGLS
VSKGAYKAKLAKVR
>Mature_414_residues
MQHLNKAMKKLHVMVKPVGAACNLDCTYCYYLSKSDLLDYRGEFKMNYASLEQFIKQYIQAHNAPEILFTWQGGEPTLLG
IDYFKKVVELQQKYCPQGSVILNDLQTNGVLLNDKWCQFLKENRFIVGLSIDGPKAIHDYYRVNKAGKGSFEQVYRSVLL
LQKHQVPFATLTCINNHSAQYALEIYQFLRDVLQSPQIQFIPIVEHSSFTAESSTQALIDVKVVGANAATNVTSWSVSAQ
QWGQFLCTVFDEWYENDIGKENVIYFEAMFQIWLGMTSPICTHAPLCGKGLAMELNGDVYSCDHFVYPDYKLGNINDHQL
DEMAFSKKQEDFGRGKSTTLTPQCQRCDYLFACYGECPKNRIATDKAGNIGHNFLCQGWYMFYSYIDERLAKLIKSKGLS
VSKGAYKAKLAKVR

Specific function: Involved in 'Ser-type' sulfatase maturation under anaerobic conditions. Links the heparin and the chondroitin sulfate utilization pathways which contribute to the colonization of the intestinal tract. May catalyze the activation of chondro-6- sulfatase, i

COG id: COG0641

COG function: function code R; Arylsulfatase regulator (Fe-S oxidoreductase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family [H]

Homologues:

Organism=Escherichia coli, GI48994973, Length=386, Percent_Identity=42.4870466321244, Blast_Score=337, Evalue=6e-94,
Organism=Escherichia coli, GI87081923, Length=374, Percent_Identity=40.1069518716578, Blast_Score=288, Evalue=5e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 47179; Mature: 47179

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHLNKAMKKLHVMVKPVGAACNLDCTYCYYLSKSDLLDYRGEFKMNYASLEQFIKQYIQ
CCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHCCCCEEECHHHHHHHHHHHHH
AHNAPEILFTWQGGEPTLLGIDYFKKVVELQQKYCPQGSVILNDLQTNGVLLNDKWCQFL
HCCCCEEEEEEECCCCEEECHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECHHHHHHH
KENRFIVGLSIDGPKAIHDYYRVNKAGKGSFEQVYRSVLLLQKHQVPFATLTCINNHSAQ
HCCCEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHH
YALEIYQFLRDVLQSPQIQFIPIVEHSSFTAESSTQALIDVKVVGANAATNVTSWSVSAQ
HHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCEEEEEEEEECCCCCCCCEEEECCHH
QWGQFLCTVFDEWYENDIGKENVIYFEAMFQIWLGMTSPICTHAPLCGKGLAMELNGDVY
HHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCCHHCCCCCCCCCEEEEECCCEE
SCDHFVYPDYKLGNINDHQLDEMAFSKKQEDFGRGKSTTLTPQCQRCDYLFACYGECPKN
ECCCEECCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCEEEEECCCCCCC
RIATDKAGNIGHNFLCQGWYMFYSYIDERLAKLIKSKGLSVSKGAYKAKLAKVR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MQHLNKAMKKLHVMVKPVGAACNLDCTYCYYLSKSDLLDYRGEFKMNYASLEQFIKQYIQ
CCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHCCCCEEECHHHHHHHHHHHHH
AHNAPEILFTWQGGEPTLLGIDYFKKVVELQQKYCPQGSVILNDLQTNGVLLNDKWCQFL
HCCCCEEEEEEECCCCEEECHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECHHHHHHH
KENRFIVGLSIDGPKAIHDYYRVNKAGKGSFEQVYRSVLLLQKHQVPFATLTCINNHSAQ
HCCCEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHH
YALEIYQFLRDVLQSPQIQFIPIVEHSSFTAESSTQALIDVKVVGANAATNVTSWSVSAQ
HHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCEEEEEEEEECCCCCCCCEEEECCHH
QWGQFLCTVFDEWYENDIGKENVIYFEAMFQIWLGMTSPICTHAPLCGKGLAMELNGDVY
HHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCCHHCCCCCCCCCEEEEECCCEE
SCDHFVYPDYKLGNINDHQLDEMAFSKKQEDFGRGKSTTLTPQCQRCDYLFACYGECPKN
ECCCEECCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCEEEEECCCCCCC
RIATDKAGNIGHNFLCQGWYMFYSYIDERLAKLIKSKGLSVSKGAYKAKLAKVR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1429442; 12663928 [H]