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The map label for this gene is cheB1 [H]

Identifier: 167623400

GI number: 167623400

Start: 1767620

End: 1768810

Strand: Direct

Name: cheB1 [H]

Synonym: Shal_1469

Alternate gene names: 167623400

Gene position: 1767620-1768810 (Clockwise)

Preceding gene: 167623399

Following gene: 167623401

Centisome position: 33.82

GC content: 47.94

Gene sequence:

>1191_bases
ATGGGCATTAAAGTTTTAGTCGTTGATGATTCGAGTTTTTTCAGACGACGCGTTAGTGAAATAGTTAATAAAGACTCCGA
GCTAGAGGTTGTGGGTACCGCATGTAATGGTGCTGAGGCTGTAAAAATGGCCGCAGAGCTTAATCCAAATGTGATCACCA
TGGACATTGAAATGCCGGTCATGGATGGGATCACTGCGGTAAAGCAGATCATGGCGAGCAAGCCAATTCCTATTCTAATG
TTCTCATCACTTACACATGATGGTGCCAAAGCAACGTTAGAAGCGTTAGATGCTGGTGCCTTAGACTTCTTGCCAAAGCG
TTTTGAAGATATCGCTAGCAATAAAGATGATGCGATAGCGCTATTGCAGCAACGAATTAGAGCATTAGGCCGTAGACGCT
TATTTAGACCGATTGCTAGGCCTCTGACTGGCAATGAAAGAGCGCAACCTGCAAATACTAGTAGTGCTACTAGTGAGAGG
GCCGCCGATAGAGCGCGCACCTCATCTAGCTTTTCTCGGCCGTCAGTTACCGCATCTGCGGCGAACGCTGCGGCTGCGAG
TACAACTGAAAGGTCTGCTAGTCGAGCCAGTGTTATTACTCGTGGCAGTGGAAAAAAGTATAAAGCATTACTTATCGGCA
CATCTACAGGAGGCCCGGTTGCGCTACAAAAGGTATTAACCCAACTGCCTGCGAATTATCCGCATCCTATTTTGCTTATC
CAGCATATGCCAGCCGCTTTTACACCAACCTTTGCAACAAGGCTTAATAGCTTGTGTAAGATTGAAGTTAAAGAGGCGGA
AACCGGCGATCAGTTAAAGCCAGGCTGCGCATACCTAGCGCCAGGCGGCATGCAAATGATGTTAGAGCGAGGCGGAGCTT
ACGGCAGAATCAAGGTGATTGCGGGTAAGGCCGATATGAATTACAAACCTTGTGTCGATATCACCTTCGCCTCAGCTTCT
AAAGTGATTGGTGGAGACGTATTGGCTGTGGTATTGACGGGCATGGGAGCCGATGGTCGAGAAGGAGCGAGAATGCTTAA
AGGCATCGGCGCTACTGTGTGGGCGCAGGATGAGGCAAGCTGTGTGGTTTATGGTATGCCACAAGCGGTAACGGCAGCTG
GTATTGCGACTAAATCGATAGCCTTAGAGCATATGGCTGAATCTATTATAAAAGAGACCTGCAATGGCTAA

Upstream 100 bases:

>100_bases
TAATAGGAGCTAGCTCTGGTTAGCTTAGGGAATAACGCTTTGTTATTCCCTTTTTTACATACAGCATTGAGCAGGCCTGT
GGTGCAGTAAAGGAATTTGA

Downstream 100 bases:

>100_bases
GATGGCTTTTGGCCAAAATGTCATTTTGCAACGCGGTGAAATGAATACGCTGTCGTTGCTATTACTGTTTTTGCTGAGTA
TTGCATCTTTTACGTTCGGT

Product: chemotaxis-specific methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MGIKVLVVDDSSFFRRRVSEIVNKDSELEVVGTACNGAEAVKMAAELNPNVITMDIEMPVMDGITAVKQIMASKPIPILM
FSSLTHDGAKATLEALDAGALDFLPKRFEDIASNKDDAIALLQQRIRALGRRRLFRPIARPLTGNERAQPANTSSATSER
AADRARTSSSFSRPSVTASAANAAAASTTERSASRASVITRGSGKKYKALLIGTSTGGPVALQKVLTQLPANYPHPILLI
QHMPAAFTPTFATRLNSLCKIEVKEAETGDQLKPGCAYLAPGGMQMMLERGGAYGRIKVIAGKADMNYKPCVDITFASAS
KVIGGDVLAVVLTGMGADGREGARMLKGIGATVWAQDEASCVVYGMPQAVTAAGIATKSIALEHMAESIIKETCNG

Sequences:

>Translated_396_residues
MGIKVLVVDDSSFFRRRVSEIVNKDSELEVVGTACNGAEAVKMAAELNPNVITMDIEMPVMDGITAVKQIMASKPIPILM
FSSLTHDGAKATLEALDAGALDFLPKRFEDIASNKDDAIALLQQRIRALGRRRLFRPIARPLTGNERAQPANTSSATSER
AADRARTSSSFSRPSVTASAANAAAASTTERSASRASVITRGSGKKYKALLIGTSTGGPVALQKVLTQLPANYPHPILLI
QHMPAAFTPTFATRLNSLCKIEVKEAETGDQLKPGCAYLAPGGMQMMLERGGAYGRIKVIAGKADMNYKPCVDITFASAS
KVIGGDVLAVVLTGMGADGREGARMLKGIGATVWAQDEASCVVYGMPQAVTAAGIATKSIALEHMAESIIKETCNG
>Mature_395_residues
GIKVLVVDDSSFFRRRVSEIVNKDSELEVVGTACNGAEAVKMAAELNPNVITMDIEMPVMDGITAVKQIMASKPIPILMF
SSLTHDGAKATLEALDAGALDFLPKRFEDIASNKDDAIALLQQRIRALGRRRLFRPIARPLTGNERAQPANTSSATSERA
ADRARTSSSFSRPSVTASAANAAAASTTERSASRASVITRGSGKKYKALLIGTSTGGPVALQKVLTQLPANYPHPILLIQ
HMPAAFTPTFATRLNSLCKIEVKEAETGDQLKPGCAYLAPGGMQMMLERGGAYGRIKVIAGKADMNYKPCVDITFASASK
VIGGDVLAVVLTGMGADGREGARMLKGIGATVWAQDEASCVVYGMPQAVTAAGIATKSIALEHMAESIIKETCNG

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=394, Percent_Identity=35.5329949238579, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1790299, Length=127, Percent_Identity=36.2204724409449, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 41785; Mature: 41654

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIKVLVVDDSSFFRRRVSEIVNKDSELEVVGTACNGAEAVKMAAELNPNVITMDIEMPV
CCEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCH
MDGITAVKQIMASKPIPILMFSSLTHDGAKATLEALDAGALDFLPKRFEDIASNKDDAIA
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHH
LLQQRIRALGRRRLFRPIARPLTGNERAQPANTSSATSERAADRARTSSSFSRPSVTASA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHH
ANAAAASTTERSASRASVITRGSGKKYKALLIGTSTGGPVALQKVLTQLPANYPHPILLI
HHHHHHCCHHHHHHHHHEEECCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEE
QHMPAAFTPTFATRLNSLCKIEVKEAETGDQLKPGCAYLAPGGMQMMLERGGAYGRIKVI
ECCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCCHHHHHHHCCCCCEEEEEE
AGKADMNYKPCVDITFASASKVIGGDVLAVVLTGMGADGREGARMLKGIGATVWAQDEAS
EECCCCCCCCCEEEEECCCCHHHCHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCCC
CVVYGMPQAVTAAGIATKSIALEHMAESIIKETCNG
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GIKVLVVDDSSFFRRRVSEIVNKDSELEVVGTACNGAEAVKMAAELNPNVITMDIEMPV
CEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCH
MDGITAVKQIMASKPIPILMFSSLTHDGAKATLEALDAGALDFLPKRFEDIASNKDDAIA
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHH
LLQQRIRALGRRRLFRPIARPLTGNERAQPANTSSATSERAADRARTSSSFSRPSVTASA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHH
ANAAAASTTERSASRASVITRGSGKKYKALLIGTSTGGPVALQKVLTQLPANYPHPILLI
HHHHHHCCHHHHHHHHHEEECCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEE
QHMPAAFTPTFATRLNSLCKIEVKEAETGDQLKPGCAYLAPGGMQMMLERGGAYGRIKVI
ECCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCCHHHHHHHCCCCCEEEEEE
AGKADMNYKPCVDITFASASKVIGGDVLAVVLTGMGADGREGARMLKGIGATVWAQDEAS
EECCCCCCCCCEEEEECCCCHHHCHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCCC
CVVYGMPQAVTAAGIATKSIALEHMAESIIKETCNG
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]