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The map label for this gene is cheA [H]

Identifier: 167623399

GI number: 167623399

Start: 1765229

End: 1767532

Strand: Direct

Name: cheA [H]

Synonym: Shal_1468

Alternate gene names: 167623399

Gene position: 1765229-1767532 (Clockwise)

Preceding gene: 167623398

Following gene: 167623400

Centisome position: 33.77

GC content: 46.48

Gene sequence:

>2304_bases
ATGTCCTTTGATGTTGATGAAGAGATACTGCAGGACTTTTTGATAGAAGCGGGTGAAATTTTAGAACTTCTACAAGAACA
ACTGGTCACGTTAGAAAATAACCCAGATGATACTGAACTGCTCAATGCAATTTTCAGGGGATTTCATACGGTTAAAGGCG
GTGCAGGATTCTTAGGTTTGTCACCCATGGTAGATGTCTGCCATGAAGCAGAGAATACCTTCGACCTACTGCGTACAGGC
AAACGTGAAGTTTCTGCTAATTTGATGGATGTCATTTTACAAGCAGTAGACTCAATCAACTCAATGTTTGCTGAAACGCA
AGCTGGGCAACCTCAATCCCCTGCCGAGTCTACGCTATTGGCGCAGCTTAAAACATTAAGCGCAGGTGAACTGCTTCCTT
CTGAAATGGAGGAAGCTGTTGTTAAGGCGCCTGCTGTAGAGTCTACAGTCATCGTTCAAGAGCCTATTATTGAACAGGCG
GCGCCGCAAGTACCTCAAGTGGTTGAACAAACATCACCCACAGTGGGCACGGGTAGCATTGATGATATCGATGATATCGA
ATTTGAAGCCTTGCTCGATGCTTTGCATGGTACGGGTAACGGCCCTGGCAATGCAGCGGATGAGGCTCCTACACTTTCAC
CATCTACACCGTCATTATCTGCACAGTCATTGTCAGCACAGTCGCTATCTGCATCTGATGACATTACCGATGACGAATTT
GAATCATTACTCGATGAGCTACATGGCTCCGGTCAGTTTAAAACTCAGTCGGCTGCTCCTGCGGTAATAGAGCAAAGTGG
CTCGGATGTTGATTCTGATGAAATTACCGATGATGAATTTGAACGATTACTCGATCAATTGCATGGTTCAGGCACAGGCC
CTGGTAACTCATCTAGCGTGACGGAGAGTAGTAACTCCGCTCCTGAACCGCATGAAACCAATAAATCAGAGCCTGTGGTA
CAAGCGATAACCACATCGCAGCAGGTGTCTGCAGTTAAGGCCGAAGCTAAACCTGAGCCTAAACCTGAGCATAAACCACA
GCCAAAGCCAGAACTAAAACCAGAACCAGAACTAAAGCCAGCAGCCGCAAAAGCTGCCCCAAAAGCGACCGGCAATATGC
CCCAAGGTGAAACCACGGTGCGGGTCGATACCTCAAGGCTTGATCAGATCATGAATATGGTCGGAGAGCTGGTATTAGTA
CGTAATCGTTTACTCAGTCTTGGCGTAGAGCGTGAAGATGAAGAGATGTCAAAGGCGTTAGCTAACCTTGACTTAGTGAC
TGCCGACTTACAAGGCGCAGTGATGAAGACTCGCATGCAGCCCATTAAGAAAGTCTTTGGCCGTTTTCCTCGAGTGGTTC
GTGATTTAGCTCGTAGTTTAAATAAAGATATTGATCTTGTTATGATCGGTGAAGATACCGATCTTGATAAAAATCTGGTT
GAAGCGTTAGCCGATCCATTAGTTCACTTAGTGAGAAACTCGGTCGATCATGGTATCGAAATGCCAGATGTTCGTGAGGC
TCACGGTAAAGCCCGTACAGGTACCATTACATTATCTGCAAGCCAAGAAGGCGATCACATCCTGCTTAAAATTGAGGATG
ATGGTGCTGGTATGGATCCAGAAAAACTTAAAGGGATTGCAATCAGTCGCGGCGTGCTCGATGAAGATGCCGCCGCCCGC
ATGAGCGATGAAGAAGCCTATAACCTTATCTTTGCTCCTGGGTTCTCAACCAAGGTTGAAGTTTCAGATATTTCGGGTCG
TGGTGTGGGTATGGACGTGGTTAAGACCCGTATTACCCAGCTGAACGGTTCTGTTTATATCGACTCACAACTAGGAAAGG
GCACACGCCTTGAGATTAAGGTGCCGTTAACACTGGCAATTATGCCGACCTTAATGGTGGAAGTTACCGAGCAAGTGTTT
GCTCTACCGCTGTCGAGCGTGAATGAGATATTTCACTTAGACTTGACTAAGACTAATGTGGTTGATGGTCAATTGACCGT
CATTGTCCGAGATAAAGCGGTGCCACTCTTTTATTTAGAGCAGTGGTTGTCTCGCAATAAATTGAATTTTAGGCATGGTG
ACAAACAGCATGGACATGTCGTCATCGTCCAGCTAGGTACGATGCAAATAGGTTTTGTGGTGGACTCACTCATCGGTCAA
GAAGAGGTGGTGATTAAACCGTTAGGGACATTGCTTCATGGCACTCCTGGCATGGCGGGGGCAACCATTACTTCTGATGG
TGGCATCGCACTGATTTTAGATGTGCCGGGTTTACTTAAGCATTACGCACGTAATAGGAGCTAG

Upstream 100 bases:

>100_bases
AGGTCCTATTGTGAATGCAGAACGCCGTCAAGACGTGGTGACTGGTCAAGATGAAGTTGACGATCTGCTTTCGAGTTTAG
GTTTTTAAGGGAGTCAAAGA

Downstream 100 bases:

>100_bases
CTCTGGTTAGCTTAGGGAATAACGCTTTGTTATTCCCTTTTTTACATACAGCATTGAGCAGGCCTGTGGTGCAGTAAAGG
AATTTGAATGGGCATTAAAG

Product: signal transduction histidine kinase CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 767; Mature: 766

Protein sequence:

>767_residues
MSFDVDEEILQDFLIEAGEILELLQEQLVTLENNPDDTELLNAIFRGFHTVKGGAGFLGLSPMVDVCHEAENTFDLLRTG
KREVSANLMDVILQAVDSINSMFAETQAGQPQSPAESTLLAQLKTLSAGELLPSEMEEAVVKAPAVESTVIVQEPIIEQA
APQVPQVVEQTSPTVGTGSIDDIDDIEFEALLDALHGTGNGPGNAADEAPTLSPSTPSLSAQSLSAQSLSASDDITDDEF
ESLLDELHGSGQFKTQSAAPAVIEQSGSDVDSDEITDDEFERLLDQLHGSGTGPGNSSSVTESSNSAPEPHETNKSEPVV
QAITTSQQVSAVKAEAKPEPKPEHKPQPKPELKPEPELKPAAAKAAPKATGNMPQGETTVRVDTSRLDQIMNMVGELVLV
RNRLLSLGVEREDEEMSKALANLDLVTADLQGAVMKTRMQPIKKVFGRFPRVVRDLARSLNKDIDLVMIGEDTDLDKNLV
EALADPLVHLVRNSVDHGIEMPDVREAHGKARTGTITLSASQEGDHILLKIEDDGAGMDPEKLKGIAISRGVLDEDAAAR
MSDEEAYNLIFAPGFSTKVEVSDISGRGVGMDVVKTRITQLNGSVYIDSQLGKGTRLEIKVPLTLAIMPTLMVEVTEQVF
ALPLSSVNEIFHLDLTKTNVVDGQLTVIVRDKAVPLFYLEQWLSRNKLNFRHGDKQHGHVVIVQLGTMQIGFVVDSLIGQ
EEVVIKPLGTLLHGTPGMAGATITSDGGIALILDVPGLLKHYARNRS

Sequences:

>Translated_767_residues
MSFDVDEEILQDFLIEAGEILELLQEQLVTLENNPDDTELLNAIFRGFHTVKGGAGFLGLSPMVDVCHEAENTFDLLRTG
KREVSANLMDVILQAVDSINSMFAETQAGQPQSPAESTLLAQLKTLSAGELLPSEMEEAVVKAPAVESTVIVQEPIIEQA
APQVPQVVEQTSPTVGTGSIDDIDDIEFEALLDALHGTGNGPGNAADEAPTLSPSTPSLSAQSLSAQSLSASDDITDDEF
ESLLDELHGSGQFKTQSAAPAVIEQSGSDVDSDEITDDEFERLLDQLHGSGTGPGNSSSVTESSNSAPEPHETNKSEPVV
QAITTSQQVSAVKAEAKPEPKPEHKPQPKPELKPEPELKPAAAKAAPKATGNMPQGETTVRVDTSRLDQIMNMVGELVLV
RNRLLSLGVEREDEEMSKALANLDLVTADLQGAVMKTRMQPIKKVFGRFPRVVRDLARSLNKDIDLVMIGEDTDLDKNLV
EALADPLVHLVRNSVDHGIEMPDVREAHGKARTGTITLSASQEGDHILLKIEDDGAGMDPEKLKGIAISRGVLDEDAAAR
MSDEEAYNLIFAPGFSTKVEVSDISGRGVGMDVVKTRITQLNGSVYIDSQLGKGTRLEIKVPLTLAIMPTLMVEVTEQVF
ALPLSSVNEIFHLDLTKTNVVDGQLTVIVRDKAVPLFYLEQWLSRNKLNFRHGDKQHGHVVIVQLGTMQIGFVVDSLIGQ
EEVVIKPLGTLLHGTPGMAGATITSDGGIALILDVPGLLKHYARNRS
>Mature_766_residues
SFDVDEEILQDFLIEAGEILELLQEQLVTLENNPDDTELLNAIFRGFHTVKGGAGFLGLSPMVDVCHEAENTFDLLRTGK
REVSANLMDVILQAVDSINSMFAETQAGQPQSPAESTLLAQLKTLSAGELLPSEMEEAVVKAPAVESTVIVQEPIIEQAA
PQVPQVVEQTSPTVGTGSIDDIDDIEFEALLDALHGTGNGPGNAADEAPTLSPSTPSLSAQSLSAQSLSASDDITDDEFE
SLLDELHGSGQFKTQSAAPAVIEQSGSDVDSDEITDDEFERLLDQLHGSGTGPGNSSSVTESSNSAPEPHETNKSEPVVQ
AITTSQQVSAVKAEAKPEPKPEHKPQPKPELKPEPELKPAAAKAAPKATGNMPQGETTVRVDTSRLDQIMNMVGELVLVR
NRLLSLGVEREDEEMSKALANLDLVTADLQGAVMKTRMQPIKKVFGRFPRVVRDLARSLNKDIDLVMIGEDTDLDKNLVE
ALADPLVHLVRNSVDHGIEMPDVREAHGKARTGTITLSASQEGDHILLKIEDDGAGMDPEKLKGIAISRGVLDEDAAARM
SDEEAYNLIFAPGFSTKVEVSDISGRGVGMDVVKTRITQLNGSVYIDSQLGKGTRLEIKVPLTLAIMPTLMVEVTEQVFA
LPLSSVNEIFHLDLTKTNVVDGQLTVIVRDKAVPLFYLEQWLSRNKLNFRHGDKQHGHVVIVQLGTMQIGFVVDSLIGQE
EVVIKPLGTLLHGTPGMAGATITSDGGIALILDVPGLLKHYARNRS

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=422, Percent_Identity=41.2322274881517, Blast_Score=291, Evalue=8e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82448; Mature: 82317

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFDVDEEILQDFLIEAGEILELLQEQLVTLENNPDDTELLNAIFRGFHTVKGGAGFLGL
CCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
SPMVDVCHEAENTFDLLRTGKREVSANLMDVILQAVDSINSMFAETQAGQPQSPAESTLL
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AQLKTLSAGELLPSEMEEAVVKAPAVESTVIVQEPIIEQAAPQVPQVVEQTSPTVGTGSI
HHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCHHHHHHHHCCCCCCCCCC
DDIDDIEFEALLDALHGTGNGPGNAADEAPTLSPSTPSLSAQSLSAQSLSASDDITDDEF
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHCHHHCCCCCCCCHHHH
ESLLDELHGSGQFKTQSAAPAVIEQSGSDVDSDEITDDEFERLLDQLHGSGTGPGNSSSV
HHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
TESSNSAPEPHETNKSEPVVQAITTSQQVSAVKAEAKPEPKPEHKPQPKPELKPEPELKP
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
AAAKAAPKATGNMPQGETTVRVDTSRLDQIMNMVGELVLVRNRLLSLGVEREDEEMSKAL
HHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ANLDLVTADLQGAVMKTRMQPIKKVFGRFPRVVRDLARSLNKDIDLVMIGEDTDLDKNLV
HHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHH
EALADPLVHLVRNSVDHGIEMPDVREAHGKARTGTITLSASQEGDHILLKIEDDGAGMDP
HHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCH
EKLKGIAISRGVLDEDAAARMSDEEAYNLIFAPGFSTKVEVSDISGRGVGMDVVKTRITQ
HHHCCCCEECCCCCCHHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHH
LNGSVYIDSQLGKGTRLEIKVPLTLAIMPTLMVEVTEQVFALPLSSVNEIFHLDLTKTNV
CCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCHHHHHHEEEEECCCCEE
VDGQLTVIVRDKAVPLFYLEQWLSRNKLNFRHGDKQHGHVVIVQLGTMQIGFVVDSLIGQ
ECCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCC
EEVVIKPLGTLLHGTPGMAGATITSDGGIALILDVPGLLKHYARNRS
CCEEHHHHHHHHCCCCCCCCCEEECCCCEEEEECCCHHHHHHHCCCC
>Mature Secondary Structure 
SFDVDEEILQDFLIEAGEILELLQEQLVTLENNPDDTELLNAIFRGFHTVKGGAGFLGL
CCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
SPMVDVCHEAENTFDLLRTGKREVSANLMDVILQAVDSINSMFAETQAGQPQSPAESTLL
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AQLKTLSAGELLPSEMEEAVVKAPAVESTVIVQEPIIEQAAPQVPQVVEQTSPTVGTGSI
HHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCHHHHHHHHCCCCCCCCCC
DDIDDIEFEALLDALHGTGNGPGNAADEAPTLSPSTPSLSAQSLSAQSLSASDDITDDEF
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHCHHHCCCCCCCCHHHH
ESLLDELHGSGQFKTQSAAPAVIEQSGSDVDSDEITDDEFERLLDQLHGSGTGPGNSSSV
HHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
TESSNSAPEPHETNKSEPVVQAITTSQQVSAVKAEAKPEPKPEHKPQPKPELKPEPELKP
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
AAAKAAPKATGNMPQGETTVRVDTSRLDQIMNMVGELVLVRNRLLSLGVEREDEEMSKAL
HHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ANLDLVTADLQGAVMKTRMQPIKKVFGRFPRVVRDLARSLNKDIDLVMIGEDTDLDKNLV
HHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHH
EALADPLVHLVRNSVDHGIEMPDVREAHGKARTGTITLSASQEGDHILLKIEDDGAGMDP
HHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCH
EKLKGIAISRGVLDEDAAARMSDEEAYNLIFAPGFSTKVEVSDISGRGVGMDVVKTRITQ
HHHCCCCEECCCCCCHHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHH
LNGSVYIDSQLGKGTRLEIKVPLTLAIMPTLMVEVTEQVFALPLSSVNEIFHLDLTKTNV
CCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCHHHHHHEEEEECCCCEE
VDGQLTVIVRDKAVPLFYLEQWLSRNKLNFRHGDKQHGHVVIVQLGTMQIGFVVDSLIGQ
ECCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCC
EEVVIKPLGTLLHGTPGMAGATITSDGGIALILDVPGLLKHYARNRS
CCEEHHHHHHHHCCCCCCCCCEEECCCCEEEEECCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]