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The map label for this gene is frp [H]

Identifier: 167623216

GI number: 167623216

Start: 1564193

End: 1564915

Strand: Direct

Name: frp [H]

Synonym: Shal_1282

Alternate gene names: 167623216

Gene position: 1564193-1564915 (Clockwise)

Preceding gene: 167623214

Following gene: 167623217

Centisome position: 29.93

GC content: 44.95

Gene sequence:

>723_bases
ATGAATTCAACTATAGAGGCTATTTTACAGCACCGTTCGATCAGGCATTTTACCGAGCAAAAAATTGAAGATGAAAAATT
AGAGTTGATTCTGCGTTGTGCCAATGCCGCATCAAGCTCAAGTTTCATGCAATGTTGCAGTATTATTAGAGTCAGCTTGC
CAGATGTAAGGGCCAAGCTAGCGGAGCTTGCTGGAGGGCAAACCTATGTGGAGTCTGCTTCTGAGTTTCTGGTGTTTTGT
GCTGACTTTAATCGCCATCAACAGATCCACCCTGATGCTCAACTCGGATTTACCGAACAGACCCTGATTGGGGCGATTGA
TACTGGGATCATGGGGCAAAATGCGTTGCTCGCCGCAGAATCTCTTGGTTTAGGCGGCGTCTATATTGGCGGGATCCGTA
ATAACCCGCAGCAAGTTACCGAGCTGCTTGGCTTACCAAAGCATGTACTACCGTTATTTGGTATGTGCTTAGGTTATAGT
GCCAAACTCCCCGAAGTTAAACCTCGTTTGCCATTGAGTATCGTGGTGCATCAAGAACGCTATCAAAACCTCGATAAGCA
AGAACTTGAGCAGTACGATCAGCATATAAAAATGTATTATGCCAGCAGAAGCCGTAACAACAGGCAGACATCTTGGTCAG
AGCAAATTACGGCGACCTTAAATAAGGAATCTAGACCCTTTATGCAAGGTTATATTGAGGGACAAGGGTTCAGCCTTAAG
TAA

Upstream 100 bases:

>100_bases
TCTATTTGTTTTTGAATTTTAACTAGTTTTAGCTTGTCTATTGTTTGTGTAAAGTTTGAGCATTAAGTTAAATTTTTTTG
CAAAAGGAAGTGAATAGAGT

Downstream 100 bases:

>100_bases
GTCACTTACAGGAGTCAAAGGATTAGGCTTTGATAAGCACATTAATATTAGGTTGTGCTACTTTGGTGAGACTGAATAGT
TTTGTTACAGAAACTATTAT

Product: nitroreductase A

Products: NA

Alternate protein names: Flavin reductase P; NADPH-FMN oxidoreductase [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MNSTIEAILQHRSIRHFTEQKIEDEKLELILRCANAASSSSFMQCCSIIRVSLPDVRAKLAELAGGQTYVESASEFLVFC
ADFNRHQQIHPDAQLGFTEQTLIGAIDTGIMGQNALLAAESLGLGGVYIGGIRNNPQQVTELLGLPKHVLPLFGMCLGYS
AKLPEVKPRLPLSIVVHQERYQNLDKQELEQYDQHIKMYYASRSRNNRQTSWSEQITATLNKESRPFMQGYIEGQGFSLK

Sequences:

>Translated_240_residues
MNSTIEAILQHRSIRHFTEQKIEDEKLELILRCANAASSSSFMQCCSIIRVSLPDVRAKLAELAGGQTYVESASEFLVFC
ADFNRHQQIHPDAQLGFTEQTLIGAIDTGIMGQNALLAAESLGLGGVYIGGIRNNPQQVTELLGLPKHVLPLFGMCLGYS
AKLPEVKPRLPLSIVVHQERYQNLDKQELEQYDQHIKMYYASRSRNNRQTSWSEQITATLNKESRPFMQGYIEGQGFSLK
>Mature_240_residues
MNSTIEAILQHRSIRHFTEQKIEDEKLELILRCANAASSSSFMQCCSIIRVSLPDVRAKLAELAGGQTYVESASEFLVFC
ADFNRHQQIHPDAQLGFTEQTLIGAIDTGIMGQNALLAAESLGLGGVYIGGIRNNPQQVTELLGLPKHVLPLFGMCLGYS
AKLPEVKPRLPLSIVVHQERYQNLDKQELEQYDQHIKMYYASRSRNNRQTSWSEQITATLNKESRPFMQGYIEGQGFSLK

Specific function: Involved in bioluminescence. It is a good supplier of reduced flavin mononucleotide (FMNH2) to the bioluminescence reaction [H]

COG id: COG0778

COG function: function code C; Nitroreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flavin oxidoreductase frp family [H]

Homologues:

Organism=Escherichia coli, GI1787075, Length=240, Percent_Identity=57.9166666666667, Blast_Score=277, Evalue=4e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016446
- InterPro:   IPR000415 [H]

Pfam domain/function: PF00881 Nitroreductase [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26931; Mature: 26931

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSTIEAILQHRSIRHFTEQKIEDEKLELILRCANAASSSSFMQCCSIIRVSLPDVRAKL
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHH
AELAGGQTYVESASEFLVFCADFNRHQQIHPDAQLGFTEQTLIGAIDTGIMGQNALLAAE
HHHCCCHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHH
SLGLGGVYIGGIRNNPQQVTELLGLPKHVLPLFGMCLGYSAKLPEVKPRLPLSIVVHQER
HCCCCCEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECHH
YQNLDKQELEQYDQHIKMYYASRSRNNRQTSWSEQITATLNKESRPFMQGYIEGQGFSLK
HCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHEECCCCCCCC
>Mature Secondary Structure
MNSTIEAILQHRSIRHFTEQKIEDEKLELILRCANAASSSSFMQCCSIIRVSLPDVRAKL
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHH
AELAGGQTYVESASEFLVFCADFNRHQQIHPDAQLGFTEQTLIGAIDTGIMGQNALLAAE
HHHCCCHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHH
SLGLGGVYIGGIRNNPQQVTELLGLPKHVLPLFGMCLGYSAKLPEVKPRLPLSIVVHQER
HCCCCCEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECHH
YQNLDKQELEQYDQHIKMYYASRSRNNRQTSWSEQITATLNKESRPFMQGYIEGQGFSLK
HCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8206832; 8885832 [H]