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The map label for this gene is yjcC [H]

Identifier: 167623214

GI number: 167623214

Start: 1561691

End: 1563208

Strand: Direct

Name: yjcC [H]

Synonym: Shal_1280

Alternate gene names: 167623214

Gene position: 1561691-1563208 (Clockwise)

Preceding gene: 167623213

Following gene: 167623216

Centisome position: 29.88

GC content: 41.24

Gene sequence:

>1518_bases
ATGCTCAACCGTGTGTTGAATACAAAGAATCTCCCTTGGCTGGTTGCTGCTGCCTTAATGTTGTGTGCCGTGATCTCTTA
CATTTTTACTCTGTATGAGATCTACACAAGGCTCGAAACTAGGGTTAATGACTTTGATAGCTTTTACAGTCAGCGCCTAG
AGAGTGCTAATCGGAGCTTAGTGGCTATCGAGCAGGAGCTACAAGGCTTAACTGTTGATACCTGTTCGCAAGAGGTTGTT
GATGTACTTAAAGGTCAGCTGTTAACTTCGGATAACCAAGTTATTGTTTGGGTTAGGTTTACTGGTGGGCAGCTTGTCTG
TTCGGCGCTTGGCATTTCTCAGTTACCACAGCCACAATATTATAATGTGATTGGTTCTATGGAAAATGGACTACACATTT
ATCAAGAGGTGGATAGTCGTAACCTTAATGCAAAGAAACCTATCTATGTGGGACGACACACTGAGCAGTATCAGTTGTTT
ATCGCAATAGATCTCTTACCTTATATCGAGGATAAGTTAGATAATTGCTCAGATTGCGGTATGTTTAGTATCCAGCTTGA
TAATCAATATGAACTATTCGAAATTAAAAGCAGTGATCTATATTGGGGGACTTTGAAATACAGCTCTGAAATTACCGGGC
TAACATATCGATTCTCTCTTAATTTATATACAAAGGCGTTACTGTGGTTTGGCTACTTTATCGCTGTCATTGCTTTTTTT
AGTATGCTCTTTGTTGGATGGCAGCTGTTAAAAGGAGTAATAAGGCAATATTACTGGCATAGATTGTTTACTACTGCACT
GAATAAAAAGGATTTTTATTTATCTTATCAACCTGTTGTCGATACTGAAAACTTAGACTGCTTCGGTGTTGAGGCACTAT
TAAGGTGGTCGTGTCGAGATGGAACCACTCGGAGTACCTGCGACTTCATTGGGTCACTAGAACGAGATCCTATTATGCCA
GAGGTTACTCGTTGGGTTGTTAAAACAGCGCTAACAGAGCTTAGAGAGTTGCTGGATGCGAATGTTATTCGCTGGTGCAG
TATTAATGTCAGTGCAATGGAAATAGAGCAGGGGCAGATGCTACTGTTTTTAAATGATCTAGTGGAACAAGGCTACCCCG
TTGAGTACTTGAGTTTTGAGTTAACCGAGCGGGTTCCGATTAGTAATTGGCAGCAGCTTAAACAGTTCATTCAACTCTGC
CAAGAATTAGGTTGTAAGATTAAGCTCGATGATGTCGGTACTGGTTATGGCGGGAGCTTATGTCTACAAAACTTGGACTT
TGACTACCTTAAAATCGATCAACAATTTGTTGGCCACTTAGGGACTCCACAAAGCAAGCTTTCTCTAATCGAGTCATATA
TTGCGATTGCGAAAGAGTTGAATATTAAGGTCATCGCAGAGGGCGTAGAAACCCAAGAGCAGGCAGAGATATTGAGAACA
CTCGGGGTTAACTTACATCAGGGCTGGCTTTATTCAAGGGCATTACCAGTTAAGGAGCTTAGTGCTTACCTAAAGTGA

Upstream 100 bases:

>100_bases
AGGGTTCACTCTTATACTAACTGGGATTGCTGATGCCGCAGCCTACAGTGTGGGGCTCGCATTACCGTTCAGTAGCTTTC
AATCGGTGAAGGCGTAAGGG

Downstream 100 bases:

>100_bases
TTTATCTCCCCTCTATACAAAAAACCTTAGTACAATCGTGCTAAGGCATTTGTTTTTTATTCCTGCATCGTAGCGTGGCT
AAAGATAAGAAAGTGTCAGT

Product: diguanylate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MLNRVLNTKNLPWLVAAALMLCAVISYIFTLYEIYTRLETRVNDFDSFYSQRLESANRSLVAIEQELQGLTVDTCSQEVV
DVLKGQLLTSDNQVIVWVRFTGGQLVCSALGISQLPQPQYYNVIGSMENGLHIYQEVDSRNLNAKKPIYVGRHTEQYQLF
IAIDLLPYIEDKLDNCSDCGMFSIQLDNQYELFEIKSSDLYWGTLKYSSEITGLTYRFSLNLYTKALLWFGYFIAVIAFF
SMLFVGWQLLKGVIRQYYWHRLFTTALNKKDFYLSYQPVVDTENLDCFGVEALLRWSCRDGTTRSTCDFIGSLERDPIMP
EVTRWVVKTALTELRELLDANVIRWCSINVSAMEIEQGQMLLFLNDLVEQGYPVEYLSFELTERVPISNWQQLKQFIQLC
QELGCKIKLDDVGTGYGGSLCLQNLDFDYLKIDQQFVGHLGTPQSKLSLIESYIAIAKELNIKVIAEGVETQEQAEILRT
LGVNLHQGWLYSRALPVKELSAYLK

Sequences:

>Translated_505_residues
MLNRVLNTKNLPWLVAAALMLCAVISYIFTLYEIYTRLETRVNDFDSFYSQRLESANRSLVAIEQELQGLTVDTCSQEVV
DVLKGQLLTSDNQVIVWVRFTGGQLVCSALGISQLPQPQYYNVIGSMENGLHIYQEVDSRNLNAKKPIYVGRHTEQYQLF
IAIDLLPYIEDKLDNCSDCGMFSIQLDNQYELFEIKSSDLYWGTLKYSSEITGLTYRFSLNLYTKALLWFGYFIAVIAFF
SMLFVGWQLLKGVIRQYYWHRLFTTALNKKDFYLSYQPVVDTENLDCFGVEALLRWSCRDGTTRSTCDFIGSLERDPIMP
EVTRWVVKTALTELRELLDANVIRWCSINVSAMEIEQGQMLLFLNDLVEQGYPVEYLSFELTERVPISNWQQLKQFIQLC
QELGCKIKLDDVGTGYGGSLCLQNLDFDYLKIDQQFVGHLGTPQSKLSLIESYIAIAKELNIKVIAEGVETQEQAEILRT
LGVNLHQGWLYSRALPVKELSAYLK
>Mature_505_residues
MLNRVLNTKNLPWLVAAALMLCAVISYIFTLYEIYTRLETRVNDFDSFYSQRLESANRSLVAIEQELQGLTVDTCSQEVV
DVLKGQLLTSDNQVIVWVRFTGGQLVCSALGISQLPQPQYYNVIGSMENGLHIYQEVDSRNLNAKKPIYVGRHTEQYQLF
IAIDLLPYIEDKLDNCSDCGMFSIQLDNQYELFEIKSSDLYWGTLKYSSEITGLTYRFSLNLYTKALLWFGYFIAVIAFF
SMLFVGWQLLKGVIRQYYWHRLFTTALNKKDFYLSYQPVVDTENLDCFGVEALLRWSCRDGTTRSTCDFIGSLERDPIMP
EVTRWVVKTALTELRELLDANVIRWCSINVSAMEIEQGQMLLFLNDLVEQGYPVEYLSFELTERVPISNWQQLKQFIQLC
QELGCKIKLDDVGTGYGGSLCLQNLDFDYLKIDQQFVGHLGTPQSKLSLIESYIAIAKELNIKVIAEGVETQEQAEILRT
LGVNLHQGWLYSRALPVKELSAYLK

Specific function: Overexpression reduces biofilm formation [H]

COG id: COG4943

COG function: function code T; Predicted signal transduction protein containing sensor and EAL domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=247, Percent_Identity=34.412955465587, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI87081921, Length=266, Percent_Identity=30.4511278195489, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI87081743, Length=267, Percent_Identity=32.9588014981273, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI1788502, Length=523, Percent_Identity=24.6653919694073, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI87081980, Length=247, Percent_Identity=31.1740890688259, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1787541, Length=234, Percent_Identity=29.4871794871795, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI87081845, Length=304, Percent_Identity=25.6578947368421, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI226510982, Length=238, Percent_Identity=31.0924369747899, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786507, Length=252, Percent_Identity=29.7619047619048, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788849, Length=234, Percent_Identity=28.6324786324786, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787055, Length=263, Percent_Identity=28.1368821292776, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI87082096, Length=245, Percent_Identity=27.3469387755102, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787410, Length=153, Percent_Identity=26.797385620915, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 58040; Mature: 58040

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNRVLNTKNLPWLVAAALMLCAVISYIFTLYEIYTRLETRVNDFDSFYSQRLESANRSL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VAIEQELQGLTVDTCSQEVVDVLKGQLLTSDNQVIVWVRFTGGQLVCSALGISQLPQPQY
EEEHHHHCCCCHHHHHHHHHHHHCCCEEECCCEEEEEEEECCCHHHHHHHCCCCCCCCHH
YNVIGSMENGLHIYQEVDSRNLNAKKPIYVGRHTEQYQLFIAIDLLPYIEDKLDNCSDCG
HHHHHCCCCCHHHHHHHCCCCCCCCCCEEECCCCCCEEEEEEEHHHHHHHHHCCCCCCCC
MFSIQLDNQYELFEIKSSDLYWGTLKYSSEITGLTYRFSLNLYTKALLWFGYFIAVIAFF
EEEEEECCCEEEEEEECCCEEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
SMLFVGWQLLKGVIRQYYWHRLFTTALNKKDFYLSYQPVVDTENLDCFGVEALLRWSCRD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEHHHHHHHHCCC
GTTRSTCDFIGSLERDPIMPEVTRWVVKTALTELRELLDANVIRWCSINVSAMEIEQGQM
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCE
LLFLNDLVEQGYPVEYLSFELTERVPISNWQQLKQFIQLCQELGCKIKLDDVGTGYGGSL
EEEEHHHHHCCCCEEEEEEEHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHH
CLQNLDFDYLKIDQQFVGHLGTPQSKLSLIESYIAIAKELNIKVIAEGVETQEQAEILRT
HHHCCCCHHEECCHHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHH
LGVNLHQGWLYSRALPVKELSAYLK
HCCCHHCCCHHHHCCCHHHHHHHCC
>Mature Secondary Structure
MLNRVLNTKNLPWLVAAALMLCAVISYIFTLYEIYTRLETRVNDFDSFYSQRLESANRSL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VAIEQELQGLTVDTCSQEVVDVLKGQLLTSDNQVIVWVRFTGGQLVCSALGISQLPQPQY
EEEHHHHCCCCHHHHHHHHHHHHCCCEEECCCEEEEEEEECCCHHHHHHHCCCCCCCCHH
YNVIGSMENGLHIYQEVDSRNLNAKKPIYVGRHTEQYQLFIAIDLLPYIEDKLDNCSDCG
HHHHHCCCCCHHHHHHHCCCCCCCCCCEEECCCCCCEEEEEEEHHHHHHHHHCCCCCCCC
MFSIQLDNQYELFEIKSSDLYWGTLKYSSEITGLTYRFSLNLYTKALLWFGYFIAVIAFF
EEEEEECCCEEEEEEECCCEEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
SMLFVGWQLLKGVIRQYYWHRLFTTALNKKDFYLSYQPVVDTENLDCFGVEALLRWSCRD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEHHHHHHHHCCC
GTTRSTCDFIGSLERDPIMPEVTRWVVKTALTELRELLDANVIRWCSINVSAMEIEQGQM
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCE
LLFLNDLVEQGYPVEYLSFELTERVPISNWQQLKQFIQLCQELGCKIKLDDVGTGYGGSL
EEEEHHHHHCCCCEEEEEEEHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHH
CLQNLDFDYLKIDQQFVGHLGTPQSKLSLIESYIAIAKELNIKVIAEGVETQEQAEILRT
HHHCCCCHHEECCHHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHH
LGVNLHQGWLYSRALPVKELSAYLK
HCCCHHCCCHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]