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The map label for this gene is nagA [H]

Identifier: 167623084

GI number: 167623084

Start: 1398351

End: 1399484

Strand: Direct

Name: nagA [H]

Synonym: Shal_1150

Alternate gene names: 167623084

Gene position: 1398351-1399484 (Clockwise)

Preceding gene: 167623083

Following gene: 167623085

Centisome position: 26.75

GC content: 49.65

Gene sequence:

>1134_bases
ATGAAGCAGACGATAATTGCAGATCGCGTGTTTGATGGAACTCGATTCCATACTGACTTACCTATCACCTTTGAAGATGG
TCACATCTTAGCTTTTGACACCTCGAAAGGGGCTGAAGAGTCACGCTTAAATGGCCTTATTGCACCTGGCTTTATTGATG
TACAAGTTAATGGCGGTGGAGGGGTGTTATTTAATGCCTCTGCGAGTTTAAAAGGCATCGAAACCATTGGCCAAGCTCAT
GCCAAATTTGGCACTACGGCTTATTTGCCGACGCTAATTACCGATGATGTCAGTGTTATGCGTCAGGCCGCTGATGCGGT
CGCTGAGGCGGTAAAATTAAATAGTGCAGGAGTTGTCGGTGTTCATTTTGAAGGGCCGCACTTAAGTGTGCCTAAAAAAG
GGGTGCACCCGCAGCCACATATCAGGCGTATTTCAGATGCTGAGCTTGAAGTCTTTGGTCGCCAAGACTTAGGCATTAAA
GTGGTAACGCTTGCGCCAGAGAATGTCTCACCTGAGGTGATAGAGGCCTTAGTCAAAGCTGGTGTTAAAGTCTGTTTAGG
CCACTCGAATGCCGATTACGATACGGTTAAAAGAGCACTCGCAGCCGGCGCTACAGGCTTTACCCATCTATATAATGCCA
TGTCAGCACTGGACTCTAGAAACCCTGGCATGGTTGGTGCGGCGCTAGAGAGTCAAGATGCTTGGTGTGGCTTGATTGTT
GATGGTCACCATGTGCATCCCGCTTCGGCAAGAGTGGCAATCAATGCCAAGCCTAAAGGCAAGGTGATGTTAGTTACCGA
TGCCATGCCGCCTGTAGGGCTGGATGAAGAGGTCAGCTTCGAGCTATTTGGTACTCAGGTGCAGCGAGTAGGCGATAGGC
TTAATGCGGTAACTGGTGAGCTAGCGGGTTGCGTGCTCGATATGGCTGGGGCTGTGGCGAATACGGTCAAGATGTTGGGG
CTTGAACCTGCTGAAGCACTGCGAATGGCATCTCTGTATCCCGCCCAGTTTCTAGGGTTAAGTGACAAGATGGGATCGCT
GCAAGTTGGCGGGCGAGCCGATATGGTGCTTCTGGATAATAACTTTGGTGTTGAGCAAACCTTTATTGCTGGTGAGCTCG
CTTTTAAGCGCTAG

Upstream 100 bases:

>100_bases
TCAGCAACAACATGTTAGCGCTTAAGTGCTGCATACATAGCAAATAGACGAAAAGTTGATACCCAATATACTCCGCCACA
CTTGAGTAAGTGAGAATAAA

Downstream 100 bases:

>100_bases
TCATCAGTTGAGCTCATCGGTTCCAATCAAAGTCTCTGTAGTGAATAGTAACTTGAAAAACACCGGAGACTTTGCTTTAT
AGTCAGTGCGTGAAAAGTGG

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MKQTIIADRVFDGTRFHTDLPITFEDGHILAFDTSKGAEESRLNGLIAPGFIDVQVNGGGGVLFNASASLKGIETIGQAH
AKFGTTAYLPTLITDDVSVMRQAADAVAEAVKLNSAGVVGVHFEGPHLSVPKKGVHPQPHIRRISDAELEVFGRQDLGIK
VVTLAPENVSPEVIEALVKAGVKVCLGHSNADYDTVKRALAAGATGFTHLYNAMSALDSRNPGMVGAALESQDAWCGLIV
DGHHVHPASARVAINAKPKGKVMLVTDAMPPVGLDEEVSFELFGTQVQRVGDRLNAVTGELAGCVLDMAGAVANTVKMLG
LEPAEALRMASLYPAQFLGLSDKMGSLQVGGRADMVLLDNNFGVEQTFIAGELAFKR

Sequences:

>Translated_377_residues
MKQTIIADRVFDGTRFHTDLPITFEDGHILAFDTSKGAEESRLNGLIAPGFIDVQVNGGGGVLFNASASLKGIETIGQAH
AKFGTTAYLPTLITDDVSVMRQAADAVAEAVKLNSAGVVGVHFEGPHLSVPKKGVHPQPHIRRISDAELEVFGRQDLGIK
VVTLAPENVSPEVIEALVKAGVKVCLGHSNADYDTVKRALAAGATGFTHLYNAMSALDSRNPGMVGAALESQDAWCGLIV
DGHHVHPASARVAINAKPKGKVMLVTDAMPPVGLDEEVSFELFGTQVQRVGDRLNAVTGELAGCVLDMAGAVANTVKMLG
LEPAEALRMASLYPAQFLGLSDKMGSLQVGGRADMVLLDNNFGVEQTFIAGELAFKR
>Mature_377_residues
MKQTIIADRVFDGTRFHTDLPITFEDGHILAFDTSKGAEESRLNGLIAPGFIDVQVNGGGGVLFNASASLKGIETIGQAH
AKFGTTAYLPTLITDDVSVMRQAADAVAEAVKLNSAGVVGVHFEGPHLSVPKKGVHPQPHIRRISDAELEVFGRQDLGIK
VVTLAPENVSPEVIEALVKAGVKVCLGHSNADYDTVKRALAAGATGFTHLYNAMSALDSRNPGMVGAALESQDAWCGLIV
DGHHVHPASARVAINAKPKGKVMLVTDAMPPVGLDEEVSFELFGTQVQRVGDRLNAVTGELAGCVLDMAGAVANTVKMLG
LEPAEALRMASLYPAQFLGLSDKMGSLQVGGRADMVLLDNNFGVEQTFIAGELAFKR

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=398, Percent_Identity=35.427135678392, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI224922791, Length=395, Percent_Identity=35.1898734177215, Blast_Score=188, Evalue=8e-48,
Organism=Escherichia coli, GI1786892, Length=374, Percent_Identity=39.572192513369, Blast_Score=221, Evalue=7e-59,
Organism=Caenorhabditis elegans, GI17553768, Length=355, Percent_Identity=34.0845070422535, Blast_Score=164, Evalue=8e-41,
Organism=Drosophila melanogaster, GI19920392, Length=381, Percent_Identity=36.4829396325459, Blast_Score=192, Evalue=4e-49,
Organism=Drosophila melanogaster, GI281361140, Length=395, Percent_Identity=35.1898734177215, Blast_Score=188, Evalue=6e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 39727; Mature: 39727

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQTIIADRVFDGTRFHTDLPITFEDGHILAFDTSKGAEESRLNGLIAPGFIDVQVNGGG
CCCCEEEHHCCCCCEEECCCCEEECCCEEEEEECCCCCCHHHHCCEECCCEEEEEEECCC
GVLFNASASLKGIETIGQAHAKFGTTAYLPTLITDDVSVMRQAADAVAEAVKLNSAGVVG
EEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCEEE
VHFEGPHLSVPKKGVHPQPHIRRISDAELEVFGRQDLGIKVVTLAPENVSPEVIEALVKA
EEECCCCCCCCCCCCCCCHHHCCCCCCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHC
GVKVCLGHSNADYDTVKRALAAGATGFTHLYNAMSALDSRNPGMVGAALESQDAWCGLIV
CEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEE
DGHHVHPASARVAINAKPKGKVMLVTDAMPPVGLDEEVSFELFGTQVQRVGDRLNAVTGE
ECCEECCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LAGCVLDMAGAVANTVKMLGLEPAEALRMASLYPAQFLGLSDKMGSLQVGGRADMVLLDN
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHCCCCCCCCCEEECCCCCEEEEEC
NFGVEQTFIAGELAFKR
CCCCCEEEEECEEECCC
>Mature Secondary Structure
MKQTIIADRVFDGTRFHTDLPITFEDGHILAFDTSKGAEESRLNGLIAPGFIDVQVNGGG
CCCCEEEHHCCCCCEEECCCCEEECCCEEEEEECCCCCCHHHHCCEECCCEEEEEEECCC
GVLFNASASLKGIETIGQAHAKFGTTAYLPTLITDDVSVMRQAADAVAEAVKLNSAGVVG
EEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCEEE
VHFEGPHLSVPKKGVHPQPHIRRISDAELEVFGRQDLGIKVVTLAPENVSPEVIEALVKA
EEECCCCCCCCCCCCCCCHHHCCCCCCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHC
GVKVCLGHSNADYDTVKRALAAGATGFTHLYNAMSALDSRNPGMVGAALESQDAWCGLIV
CEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEE
DGHHVHPASARVAINAKPKGKVMLVTDAMPPVGLDEEVSFELFGTQVQRVGDRLNAVTGE
ECCEECCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LAGCVLDMAGAVANTVKMLGLEPAEALRMASLYPAQFLGLSDKMGSLQVGGRADMVLLDN
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHCCCCCCCCCEEECCCCCEEEEEC
NFGVEQTFIAGELAFKR
CCCCCEEEEECEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]