Click here to switch to the map view.

The map label for this gene is tas [H]

Identifier: 167622760

GI number: 167622760

Start: 1023028

End: 1024071

Strand: Reverse

Name: tas [H]

Synonym: Shal_0820

Alternate gene names: 167622760

Gene position: 1024071-1023028 (Counterclockwise)

Preceding gene: 167622761

Following gene: 167622759

Centisome position: 19.59

GC content: 45.88

Gene sequence:

>1044_bases
ATGGAATATAGACGTCTTTCGCATTCAAGTTTAAATGTTAGTCAAATCTGTTTAGGTACAATGACTTGGGGAGAGCAAAA
CACCCAAGCACAGGCATTCGAACAACTGGATTATGCTATCGGTGAAGGCATTAACTTTATCGACACTGCTGAAATGTACC
CTGTACCACCAAAGGCTGAAACTCAGGGTGAAACTGAGCGCATCTTAGGTAACTACCTTAAGCACAAAGGCAATCGAGAA
AACTTAGTCATTACCACTAAGGTGGCCGCCCCAGGTGGTAAGAGTGACTATATCCGCCCCAATATGGCACTCGACTGGTG
TAATATCCATGCTGCAGTTAACGCATCCCTTGAGCGTTTACAAATCGATACTATCGATCTATACCAAATCCACTGGCCTG
ACAGAAACACCAACTTCTTCGGTGAGCTTAGCTACAACCAGCAAGATGAACATGAGAAGCTTACGCCGATTATCGATACT
TTAGAGGCACTATCAGATCTCATCAAAGCAGGTAAAATTCGCTATATCGGCATCTCTAACGAAACGCCTTGGGGCTTTAT
GGAGTATCTGCGCCTAGCCGAGAAACATGACTTACCTAAAATAGTCTCGGTGCAAAACCCCTATAATCTGCTAAATCGTA
GCTATGAAGTGGGGATGGCTGAAATTAGCCACCGCGAAGAGGTGCCATTACTCGCTTATTCACCACTGGCTTTTGGTGCG
CTATCGGGCAAATACCTTGATAACCAATGGCCAGAGGGGGCGAGAATGACGCTGTTTAAGCGCTTTGCTCGCTATACTGG
CACCAAGATGGCAACGGATGCCACAAAAGCCTATGTGGAGCTGGCTCGAGAGTTCAATATGAGCCCAGCGCAGATGGCCT
TAGCCTTTGTAAACTCCCAAAAGTTTGTCGCATCAAACATCATTGGCGCCACCAATCTTGAGCAGCTAAAAGAGAATATC
GACAGCATTCACTGCGCTATTTCTCCTGAGTTACAACTACGCTTAGATGAGCTAGCACTGATTTATCGCTTCCCTTGCCC
TTAA

Upstream 100 bases:

>100_bases
TTATCTGCTGAGGTATTCAAACTGCAGCTAAGTTAATGGTTTTTATTGGTAAAGCTTGCTAGCCTCAAAGTAAGTGGTCT
TCGCATATAAGTGAGTTTTT

Downstream 100 bases:

>100_bases
AAGCGATGCTTTTAACAGTCTAAACTTGCTTTAGGCGCTCAGATCTTACAAGATCTGAGCGCCTTTTTATTTTTATCGAT
AACCTTGGATCAATTAATGG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MEYRRLSHSSLNVSQICLGTMTWGEQNTQAQAFEQLDYAIGEGINFIDTAEMYPVPPKAETQGETERILGNYLKHKGNRE
NLVITTKVAAPGGKSDYIRPNMALDWCNIHAAVNASLERLQIDTIDLYQIHWPDRNTNFFGELSYNQQDEHEKLTPIIDT
LEALSDLIKAGKIRYIGISNETPWGFMEYLRLAEKHDLPKIVSVQNPYNLLNRSYEVGMAEISHREEVPLLAYSPLAFGA
LSGKYLDNQWPEGARMTLFKRFARYTGTKMATDATKAYVELAREFNMSPAQMALAFVNSQKFVASNIIGATNLEQLKENI
DSIHCAISPELQLRLDELALIYRFPCP

Sequences:

>Translated_347_residues
MEYRRLSHSSLNVSQICLGTMTWGEQNTQAQAFEQLDYAIGEGINFIDTAEMYPVPPKAETQGETERILGNYLKHKGNRE
NLVITTKVAAPGGKSDYIRPNMALDWCNIHAAVNASLERLQIDTIDLYQIHWPDRNTNFFGELSYNQQDEHEKLTPIIDT
LEALSDLIKAGKIRYIGISNETPWGFMEYLRLAEKHDLPKIVSVQNPYNLLNRSYEVGMAEISHREEVPLLAYSPLAFGA
LSGKYLDNQWPEGARMTLFKRFARYTGTKMATDATKAYVELAREFNMSPAQMALAFVNSQKFVASNIIGATNLEQLKENI
DSIHCAISPELQLRLDELALIYRFPCP
>Mature_347_residues
MEYRRLSHSSLNVSQICLGTMTWGEQNTQAQAFEQLDYAIGEGINFIDTAEMYPVPPKAETQGETERILGNYLKHKGNRE
NLVITTKVAAPGGKSDYIRPNMALDWCNIHAAVNASLERLQIDTIDLYQIHWPDRNTNFFGELSYNQQDEHEKLTPIIDT
LEALSDLIKAGKIRYIGISNETPWGFMEYLRLAEKHDLPKIVSVQNPYNLLNRSYEVGMAEISHREEVPLLAYSPLAFGA
LSGKYLDNQWPEGARMTLFKRFARYTGTKMATDATKAYVELAREFNMSPAQMALAFVNSQKFVASNIIGATNLEQLKENI
DSIHCAISPELQLRLDELALIYRFPCP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=333, Percent_Identity=32.4324324324324, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI4504825, Length=331, Percent_Identity=32.3262839879154, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI27436964, Length=333, Percent_Identity=31.5315315315315, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI27436962, Length=333, Percent_Identity=31.5315315315315, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI27436966, Length=333, Percent_Identity=31.2312312312312, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436971, Length=352, Percent_Identity=28.9772727272727, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI223718702, Length=292, Percent_Identity=26.027397260274, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI41327764, Length=321, Percent_Identity=25.8566978193146, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI41152114, Length=321, Percent_Identity=25.5451713395639, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1789199, Length=348, Percent_Identity=55.1724137931034, Blast_Score=397, Evalue=1e-112,
Organism=Escherichia coli, GI87081735, Length=345, Percent_Identity=31.8840579710145, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1789375, Length=340, Percent_Identity=28.8235294117647, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788070, Length=293, Percent_Identity=29.6928327645051, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788081, Length=354, Percent_Identity=27.4011299435028, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325169, Length=260, Percent_Identity=30.3846153846154, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6323998, Length=342, Percent_Identity=24.8538011695906, Blast_Score=93, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6319958, Length=315, Percent_Identity=24.7619047619048, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319951, Length=341, Percent_Identity=23.7536656891496, Blast_Score=79, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6322615, Length=259, Percent_Identity=23.5521235521236, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24646159, Length=340, Percent_Identity=25.5882352941176, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 39362; Mature: 39362

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRRLSHSSLNVSQICLGTMTWGEQNTQAQAFEQLDYAIGEGINFIDTAEMYPVPPKAE
CCCCCCCCCCCCHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCC
TQGETERILGNYLKHKGNRENLVITTKVAAPGGKSDYIRPNMALDWCNIHAAVNASLERL
CCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEHHHHHHHHCCCHHHE
QIDTIDLYQIHWPDRNTNFFGELSYNQQDEHEKLTPIIDTLEALSDLIKAGKIRYIGISN
EECEEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
ETPWGFMEYLRLAEKHDLPKIVSVQNPYNLLNRSYEVGMAEISHREEVPLLAYSPLAFGA
CCCHHHHHHHHHHHHCCCCCEEECCCCHHHHCCCHHCCHHHHCCCCCCCEEEECCHHHHC
LSGKYLDNQWPEGARMTLFKRFARYTGTKMATDATKAYVELAREFNMSPAQMALAFVNSQ
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
KFVASNIIGATNLEQLKENIDSIHCAISPELQLRLDELALIYRFPCP
HHHHHHCCCCCCHHHHHHHHHHEEEEECCHHHEEHHHEEEEEECCCC
>Mature Secondary Structure
MEYRRLSHSSLNVSQICLGTMTWGEQNTQAQAFEQLDYAIGEGINFIDTAEMYPVPPKAE
CCCCCCCCCCCCHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCC
TQGETERILGNYLKHKGNRENLVITTKVAAPGGKSDYIRPNMALDWCNIHAAVNASLERL
CCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEHHHHHHHHCCCHHHE
QIDTIDLYQIHWPDRNTNFFGELSYNQQDEHEKLTPIIDTLEALSDLIKAGKIRYIGISN
EECEEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
ETPWGFMEYLRLAEKHDLPKIVSVQNPYNLLNRSYEVGMAEISHREEVPLLAYSPLAFGA
CCCHHHHHHHHHHHHCCCCCEEECCCCHHHHCCCHHCCHHHHCCCCCCCEEEECCHHHHC
LSGKYLDNQWPEGARMTLFKRFARYTGTKMATDATKAYVELAREFNMSPAQMALAFVNSQ
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
KFVASNIIGATNLEQLKENIDSIHCAISPELQLRLDELALIYRFPCP
HHHHHHCCCCCCHHHHHHHHHHEEEEECCHHHEEHHHEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]