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The map label for this gene is actR [H]

Identifier: 167622552

GI number: 167622552

Start: 738991

End: 739545

Strand: Direct

Name: actR [H]

Synonym: Shal_0612

Alternate gene names: 167622552

Gene position: 738991-739545 (Clockwise)

Preceding gene: 167622551

Following gene: 167622558

Centisome position: 14.14

GC content: 49.55

Gene sequence:

>555_bases
ATGACTAAAAAACTACTCATTATTGAGGATGATATCGCCTTAGCGAGTGTGCTTGTCAGGCGCATGACCAAGCAGGGGTT
TGAGTGTCAACAGTGTCATGATGCGACTCAGGGCCTGCTGTTAGCACGACAGTTTCGCCCGACTCATCTGCTGTTAGACA
TGAAGTTGGATCAAGAAAATGGCTTGAAACTCATCTCGCCACTCAGGCAGTTGCTACCGGATGTGGTGATGGTATTGCTT
ACGGGCTATGCCAGCATTGCCACCGCCGTAGAGGCTATCCGCTTAGGGGCTGATAACTATCTGGCGAAGCCTGTCGATAC
TCAGACCTTGTTTAATGCGCTATCGACGACTCCCTTCGACAGTATGATTGAATCCTTGATAGAGGAGCCATTATCGCCTA
AGCGTCTGGAGTGGGAGCATATTCAGCAGGTATTGAATGCCAATAGTGGCAACGTGTCTGCAACTGCGCGCCAACTTGGA
ATGCATAGGCGTACTCTACAGCGTAAGTTACTGAAGAAACCCACGGCTGATCATCGAGAGCTATCGCTCGCTTAA

Upstream 100 bases:

>100_bases
CGTCTGGGTGGGCAGCTACTTTTGGGCTCAGCGAAAGAGGGCGGCACGGTTGCCGAGGTATGTTTCCCGGTTTGGCATGC
AGGCGTCGATGGAGAGTGTC

Downstream 100 bases:

>100_bases
TATTTTACAGATGAACTCACGCTCGCTAGTAAAGCTATCGGTGGCGGTGCCAATACAGGATGTTGTGCTGGGGGCGCTTT
TCGATAACAAAGAACATCGT

Product: two component Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MTKKLLIIEDDIALASVLVRRMTKQGFECQQCHDATQGLLLARQFRPTHLLLDMKLDQENGLKLISPLRQLLPDVVMVLL
TGYASIATAVEAIRLGADNYLAKPVDTQTLFNALSTTPFDSMIESLIEEPLSPKRLEWEHIQQVLNANSGNVSATARQLG
MHRRTLQRKLLKKPTADHRELSLA

Sequences:

>Translated_184_residues
MTKKLLIIEDDIALASVLVRRMTKQGFECQQCHDATQGLLLARQFRPTHLLLDMKLDQENGLKLISPLRQLLPDVVMVLL
TGYASIATAVEAIRLGADNYLAKPVDTQTLFNALSTTPFDSMIESLIEEPLSPKRLEWEHIQQVLNANSGNVSATARQLG
MHRRTLQRKLLKKPTADHRELSLA
>Mature_183_residues
TKKLLIIEDDIALASVLVRRMTKQGFECQQCHDATQGLLLARQFRPTHLLLDMKLDQENGLKLISPLRQLLPDVVMVLLT
GYASIATAVEAIRLGADNYLAKPVDTQTLFNALSTTPFDSMIESLIEEPLSPKRLEWEHIQQVLNANSGNVSATARQLGM
HRRTLQRKLLKKPTADHRELSLA

Specific function: Member of the two-component regulatory system ActS/ActR acting in acid tolerance. These data implicate that a two- component sensor may be involved in pH sensing and/or response [H]

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=30.5555555555556, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI1788905, Length=110, Percent_Identity=28.1818181818182, Blast_Score=60, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 20649; Mature: 20518

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKLLIIEDDIALASVLVRRMTKQGFECQQCHDATQGLLLARQFRPTHLLLDMKLDQEN
CCCCEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCC
GLKLISPLRQLLPDVVMVLLTGYASIATAVEAIRLGADNYLAKPVDTQTLFNALSTTPFD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHH
SMIESLIEEPLSPKRLEWEHIQQVLNANSGNVSATARQLGMHRRTLQRKLLKKPTADHRE
HHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LSLA
CCCC
>Mature Secondary Structure 
TKKLLIIEDDIALASVLVRRMTKQGFECQQCHDATQGLLLARQFRPTHLLLDMKLDQEN
CCCEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCC
GLKLISPLRQLLPDVVMVLLTGYASIATAVEAIRLGADNYLAKPVDTQTLFNALSTTPFD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHH
SMIESLIEEPLSPKRLEWEHIQQVLNANSGNVSATARQLGMHRRTLQRKLLKKPTADHRE
HHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LSLA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]