Click here to switch to the map view.

The map label for this gene is yafC [H]

Identifier: 167622558

GI number: 167622558

Start: 746188

End: 747102

Strand: Direct

Name: yafC [H]

Synonym: Shal_0618

Alternate gene names: 167622558

Gene position: 746188-747102 (Clockwise)

Preceding gene: 167622552

Following gene: 167622559

Centisome position: 14.28

GC content: 47.32

Gene sequence:

>915_bases
ATGTATCAAGACCTAAATTTAGCAGATGTGCGAGCTTTTACCGTGATAGCGGAAAAGGGCAGTTTTACCATTGCCGCTGA
AAAGCTCGGTTGTTCTCGCTCACACCTTTCTAAGCAATTGACTCAGTTAGAGCGTTACCTAGGTGTCACCTTGATCACCC
GCACCACTAGGGCTCAGCGGTTAACTGAGCAGGGACGCTTTTTCTATGAGCGCTGCCAACATGCGCTAGACATCATGGAG
CAAGCGGTGGCGAAGACGGTTGATGATGCCCATAACCTGCAGGGCAAGATTAACATCAACTGTGTGGGAGGCTATATCGG
TGAGGAGATCGTGAACCAACTGGTTAATGACTTTATGACTCTGCACCCCAATATTCAGGTGCACTTAGATTTCAGTAGCC
AGAGAGTCGACTTGGTGCTCGATGAGTTTGATTTGGTCTTTAGAATGGGTGAGCTTGAGGATTCAGGCTTAGTGGCCAGA
AAGCTGATGGATATTGCAAATTGTACCTTGGCATCGCCACGTTATATCGCCAAGCATGGCAGACCCGAACACCCTAAAGA
GCTCAAGCATCATGCCTGTGTTACCGGCTCGGTTCATCATTGGAGTTATCACCGTCGTAGCAATAAGAGTCATAAGACAG
AGGTGACGATTACTGGAGCCTTGCTGTGTAAGAATGGCAGAGTGATGAAAAGTAGCGCCTTGGCGGGAAATGGTATCGTG
CGCTTGCCAGAGATTTACTGCAGTGCAGAGCTCAACGCGGGCACTCTGGTACATCTGTTTGATGATTGGGCTATCTCAGA
TACGCCGCTTTATCTGCTCTATAACCGAGATCAATTTCAGCCAGCTAGGTTGAGGCAGTTTATCGAATTTACCATTCAAA
ACTTTATGAAATATGTCGAGTTACCAAATGCCTAA

Upstream 100 bases:

>100_bases
CGAACCCAATATTGTTGATATATAATCTATAGAGAATATGATTGTTTACATATGACTCCTAATCAGTCTCTGTTATCTAA
GATAAAACGAGTTCCTATTT

Downstream 100 bases:

>100_bases
ATAAGCTTAGGTAGCTGACCTCTTGAGGCTTGAGTCACTCGGGTCATCCATCTTTCGACCTAATTGCTATTAGAATGTAG
ATTTAAAGTTAAGTTTAACC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MYQDLNLADVRAFTVIAEKGSFTIAAEKLGCSRSHLSKQLTQLERYLGVTLITRTTRAQRLTEQGRFFYERCQHALDIME
QAVAKTVDDAHNLQGKININCVGGYIGEEIVNQLVNDFMTLHPNIQVHLDFSSQRVDLVLDEFDLVFRMGELEDSGLVAR
KLMDIANCTLASPRYIAKHGRPEHPKELKHHACVTGSVHHWSYHRRSNKSHKTEVTITGALLCKNGRVMKSSALAGNGIV
RLPEIYCSAELNAGTLVHLFDDWAISDTPLYLLYNRDQFQPARLRQFIEFTIQNFMKYVELPNA

Sequences:

>Translated_304_residues
MYQDLNLADVRAFTVIAEKGSFTIAAEKLGCSRSHLSKQLTQLERYLGVTLITRTTRAQRLTEQGRFFYERCQHALDIME
QAVAKTVDDAHNLQGKININCVGGYIGEEIVNQLVNDFMTLHPNIQVHLDFSSQRVDLVLDEFDLVFRMGELEDSGLVAR
KLMDIANCTLASPRYIAKHGRPEHPKELKHHACVTGSVHHWSYHRRSNKSHKTEVTITGALLCKNGRVMKSSALAGNGIV
RLPEIYCSAELNAGTLVHLFDDWAISDTPLYLLYNRDQFQPARLRQFIEFTIQNFMKYVELPNA
>Mature_304_residues
MYQDLNLADVRAFTVIAEKGSFTIAAEKLGCSRSHLSKQLTQLERYLGVTLITRTTRAQRLTEQGRFFYERCQHALDIME
QAVAKTVDDAHNLQGKININCVGGYIGEEIVNQLVNDFMTLHPNIQVHLDFSSQRVDLVLDEFDLVFRMGELEDSGLVAR
KLMDIANCTLASPRYIAKHGRPEHPKELKHHACVTGSVHHWSYHRRSNKSHKTEVTITGALLCKNGRVMKSSALAGNGIV
RLPEIYCSAELNAGTLVHLFDDWAISDTPLYLLYNRDQFQPARLRQFIEFTIQNFMKYVELPNA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=283, Percent_Identity=31.095406360424, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI145693193, Length=296, Percent_Identity=27.7027027027027, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI87081978, Length=294, Percent_Identity=28.9115646258503, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787128, Length=295, Percent_Identity=27.1186440677966, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=28.8194444444444, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789639, Length=300, Percent_Identity=27.6666666666667, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787589, Length=276, Percent_Identity=27.8985507246377, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1789173, Length=288, Percent_Identity=23.2638888888889, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790011, Length=299, Percent_Identity=24.0802675585284, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787601, Length=297, Percent_Identity=24.9158249158249, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786448, Length=254, Percent_Identity=25.5905511811024, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788706, Length=174, Percent_Identity=27.0114942528736, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI157672245, Length=154, Percent_Identity=30.5194805194805, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34562; Mature: 34562

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQDLNLADVRAFTVIAEKGSFTIAAEKLGCSRSHLSKQLTQLERYLGVTLITRTTRAQR
CCCCCCHHHHEEEEEEEECCCEEEEHHHHCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHH
LTEQGRFFYERCQHALDIMEQAVAKTVDDAHNLQGKININCVGGYIGEEIVNQLVNDFMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHE
LHPNIQVHLDFSSQRVDLVLDEFDLVFRMGELEDSGLVARKLMDIANCTLASPRYIAKHG
ECCCEEEEEECCCCCEEHHHHHHHHHHEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHCC
RPEHPKELKHHACVTGSVHHWSYHRRSNKSHKTEVTITGALLCKNGRVMKSSALAGNGIV
CCCCHHHHHHHHEECCCCHHHHHHHCCCCCCCEEEEEEEEEEECCCCEEECCCCCCCCCE
RLPEIYCSAELNAGTLVHLFDDWAISDTPLYLLYNRDQFQPARLRQFIEFTIQNFMKYVE
ECCCEEEEEECCCCEEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHC
LPNA
CCCC
>Mature Secondary Structure
MYQDLNLADVRAFTVIAEKGSFTIAAEKLGCSRSHLSKQLTQLERYLGVTLITRTTRAQR
CCCCCCHHHHEEEEEEEECCCEEEEHHHHCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHH
LTEQGRFFYERCQHALDIMEQAVAKTVDDAHNLQGKININCVGGYIGEEIVNQLVNDFMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHE
LHPNIQVHLDFSSQRVDLVLDEFDLVFRMGELEDSGLVARKLMDIANCTLASPRYIAKHG
ECCCEEEEEECCCCCEEHHHHHHHHHHEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHCC
RPEHPKELKHHACVTGSVHHWSYHRRSNKSHKTEVTITGALLCKNGRVMKSSALAGNGIV
CCCCHHHHHHHHEECCCCHHHHHHHCCCCCCCEEEEEEEEEEECCCCEEECCCCCCCCCE
RLPEIYCSAELNAGTLVHLFDDWAISDTPLYLLYNRDQFQPARLRQFIEFTIQNFMKYVE
ECCCEEEEEECCCCEEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHC
LPNA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]