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The map label for this gene is yrbG [H]

Identifier: 167622326

GI number: 167622326

Start: 452235

End: 453161

Strand: Reverse

Name: yrbG [H]

Synonym: Shal_0386

Alternate gene names: 167622326

Gene position: 453161-452235 (Counterclockwise)

Preceding gene: 167622327

Following gene: 167622325

Centisome position: 8.67

GC content: 44.98

Gene sequence:

>927_bases
ATGTTTATTTTATTGTCGATACTCGGCGGTTTTTTAATTCTGACTGTAGGTGCTGAAGCCTTAGTTAGAGGTGCAAGCCA
AATAGCACTGAGATTGGGGCTTACGCCTCTGCTCATCGGCCTGACTATTGTTGCCTTTGGTACCAGTGCACCAGAGCTTG
CTGTTAGTGTTAAGTCTGCGATTGCCGGTAATAGCGGTATCGCTTTGGGTAACGTGATTGGCTCAAACATCGCTAATATT
GGCCTTATTTTAGGTATCACTGCACTTATTCGCCCAATTAAGATTGAGTCACAAATGGTACGCCGCGATATTCCTATCAT
GATTGCTGCGTCACTACTGTTTTGGAGCCTATTACTCGATGGTGGCTTGAGCTTCTGGGATGGTGCGATTCTATCTGCGT
TGCTTGTCGCTTACTTAACCTTCAGCTACTTAACCGCAGAAAAACAAACTGACGACGATATTGAAGATGCTCAGCAAAAC
CCAATGCTATCAGTATTGTTTATTGTTATCGGTATTAGCATGCTTGTGGGCGGTGGTATTTTATTCGTTGACGGCGCAGT
CGCTATGGCAAAATCATTCGGCATTAGCGAAGTGATTATCGGTTTAACGATTGTTGCGATTGGTACCAGCATGCCAGAGC
TTGTCACCTCGATTGTGGCAGCGCTTAAAGGCCAGAGTGATATTGCAATTGGTAACGTTGTTGGCTCAAATATCTTCAAC
GTACTCGGTATTCTAGGTGTAACAGCGCTAATTCACCCGATTATTGGCAGTGAAATTAGCAACCTAGATTGGGCTGCTAT
GATTGCCCTAGCGGTGTTATTGCTACCTTTTGCTTACACCGGCCTGCGCATTGGACGCCGTGAAGCGAGTTTATTGATTG
CAGGCTATGTAGCCTATATCGGCTATATCGTTTCACAAGCCGTTTAA

Upstream 100 bases:

>100_bases
AACTAAATTTAATGGTGGATGAACAGTTTTTGATTGCGCAATTTTTGAAAAAAACTATTCTTGCCATCCTTTCAAAGAAA
TCCAATTTATAGAGTTGATC

Downstream 100 bases:

>100_bases
TTAGCGACGCCCCAGAAATTGCTTAAATGAATAGGCCTAACGTGCAAATTATACGTTAGGCCTTTTTTGTTTTATATACA
CTGTTATCATCAGATTTGCG

Product: CaCA family Na(+)/Ca(+) antiporter

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MFILLSILGGFLILTVGAEALVRGASQIALRLGLTPLLIGLTIVAFGTSAPELAVSVKSAIAGNSGIALGNVIGSNIANI
GLILGITALIRPIKIESQMVRRDIPIMIAASLLFWSLLLDGGLSFWDGAILSALLVAYLTFSYLTAEKQTDDDIEDAQQN
PMLSVLFIVIGISMLVGGGILFVDGAVAMAKSFGISEVIIGLTIVAIGTSMPELVTSIVAALKGQSDIAIGNVVGSNIFN
VLGILGVTALIHPIIGSEISNLDWAAMIALAVLLLPFAYTGLRIGRREASLLIAGYVAYIGYIVSQAV

Sequences:

>Translated_308_residues
MFILLSILGGFLILTVGAEALVRGASQIALRLGLTPLLIGLTIVAFGTSAPELAVSVKSAIAGNSGIALGNVIGSNIANI
GLILGITALIRPIKIESQMVRRDIPIMIAASLLFWSLLLDGGLSFWDGAILSALLVAYLTFSYLTAEKQTDDDIEDAQQN
PMLSVLFIVIGISMLVGGGILFVDGAVAMAKSFGISEVIIGLTIVAIGTSMPELVTSIVAALKGQSDIAIGNVVGSNIFN
VLGILGVTALIHPIIGSEISNLDWAAMIALAVLLLPFAYTGLRIGRREASLLIAGYVAYIGYIVSQAV
>Mature_308_residues
MFILLSILGGFLILTVGAEALVRGASQIALRLGLTPLLIGLTIVAFGTSAPELAVSVKSAIAGNSGIALGNVIGSNIANI
GLILGITALIRPIKIESQMVRRDIPIMIAASLLFWSLLLDGGLSFWDGAILSALLVAYLTFSYLTAEKQTDDDIEDAQQN
PMLSVLFIVIGISMLVGGGILFVDGAVAMAKSFGISEVIIGLTIVAIGTSMPELVTSIVAALKGQSDIAIGNVVGSNIFN
VLGILGVTALIHPIIGSEISNLDWAAMIALAVLLLPFAYTGLRIGRREASLLIAGYVAYIGYIVSQAV

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Homo sapiens, GI4759128, Length=75, Percent_Identity=46.6666666666667, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1789587, Length=298, Percent_Identity=36.9127516778523, Blast_Score=146, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 31919; Mature: 31919

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFILLSILGGFLILTVGAEALVRGASQIALRLGLTPLLIGLTIVAFGTSAPELAVSVKSA
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
IAGNSGIALGNVIGSNIANIGLILGITALIRPIKIESQMVRRDIPIMIAASLLFWSLLLD
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GGLSFWDGAILSALLVAYLTFSYLTAEKQTDDDIEDAQQNPMLSVLFIVIGISMLVGGGI
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCC
LFVDGAVAMAKSFGISEVIIGLTIVAIGTSMPELVTSIVAALKGQSDIAIGNVVGSNIFN
EEECHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHH
VLGILGVTALIHPIIGSEISNLDWAAMIALAVLLLPFAYTGLRIGRREASLLIAGYVAYI
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GYIVSQAV
HHHHHHCC
>Mature Secondary Structure
MFILLSILGGFLILTVGAEALVRGASQIALRLGLTPLLIGLTIVAFGTSAPELAVSVKSA
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
IAGNSGIALGNVIGSNIANIGLILGITALIRPIKIESQMVRRDIPIMIAASLLFWSLLLD
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GGLSFWDGAILSALLVAYLTFSYLTAEKQTDDDIEDAQQNPMLSVLFIVIGISMLVGGGI
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCC
LFVDGAVAMAKSFGISEVIIGLTIVAIGTSMPELVTSIVAALKGQSDIAIGNVVGSNIFN
EEECHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHH
VLGILGVTALIHPIIGSEISNLDWAAMIALAVLLLPFAYTGLRIGRREASLLIAGYVAYI
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GYIVSQAV
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]