Click here to switch to the map view.

The map label for this gene is recG [H]

Identifier: 167622325

GI number: 167622325

Start: 450002

End: 452092

Strand: Reverse

Name: recG [H]

Synonym: Shal_0385

Alternate gene names: 167622325

Gene position: 452092-450002 (Counterclockwise)

Preceding gene: 167622326

Following gene: 167622324

Centisome position: 8.65

GC content: 50.88

Gene sequence:

>2091_bases
TTGAGTGCTAACCGTTTGCAAAGACTCGATCTTGTTCCTATAACAGATCTTAAGGGCGTCGCCAACAAGATGGCCGAGAG
ATTAGCCAAGCTGAGTATAACAACAGTGCAAGACCTGTTGTTTCATCTGCCGCTTCGCTATGAGGATCGCACTCAAGTCT
ACCCAATTGCCTCGCTTTACCCGGGCAGTTACGGCACCATCGAAGCCGTTATTCAATCAAGCCAGATTATTCAAGGCCGT
AAGCGCATGCTGACCTGCACGGTGCGCGATGATACTGGCAGCTTAACTCTGCGCTTTTTTAATTTCTCTGTCGCGCAGCG
CAACGGCCTAGAGATAGGTATGACCATTCGTGCCTATGGTGAAATTCGCCGCGGTAAGCATTTTGCAGAGATCATTCATC
CAGAATACAAGTTGATCTCCCCTGGTGAAGATCTGCAGCTGAGCGACACATTGACGCCGGTTTACCCCACGACCGAGGGC
CTAAAACAAGCAAGCTGGATTAAGCTCACCGAGCAAGCACTTGCCATGTTAGACAATGGCGGCTTACAAGAATTACTGCC
GCCAAACCTGCAGCCAAATAACTTGGATTTAAAGCAAGCGTTGCAAATCCTGCATCGACCTAATAATCAGGTGTCGCTAT
TTGAGCTGGAGCAAGGCACTCATCCGGCGCAGCAACGCCTGATTCAAGAAGAGTTACTGGCCCACAACTTGAGTATGTTA
CGCCTACGTCAGCGTAGTAACCGCGACAAAGCAGTCAGCATGCATGCCACGGGGCAGTTACTCAATCCGTTTTTAGCCTC
GCTCCCCTTTAAACCTACTGGGGCGCAGCAACGAGTGGTTGCAGATATAACCCAAGATTTAGCTAAGCACGAGCCGATGA
TGCGCCTAGTACAAGGTGATGTGGGTTCAGGTAAGACCTTGATTGCAGCCCTTGCGGCACTGCAAGCGATAGAAAGCGGT
TACCAAGTGGCCATGATGGCGCCAACCGAGCTATTGGCCGAGCAACACGCGCTAAACTTTAGCAGCTGGTTTGAACCATT
AGGCCTTAAAGTCGGCTGGCTTGCAGGTAAGTTAAAAGGTAAGGCCAGAGCCCAGTCGTTAGCCGATATTGAATCAGGCG
ATGCCCACATTGTCATAGGTACCCATGCTATTTTCCAAGAGCAAGTGGTGTTCAACAAGCTGGCACTGATTATTATCGAT
GAGCAGCATAGGTTTGGCGTACATCAACGCTTAGGTCTGCGAGAAAAAGGCATCAGCCAAGGCTTTCATCCTCACCAGTT
AATTATGACCGCGACTCCCATTCCGCGCACGCTCGCCATGACGGCCTATGCCGATCTCGATACCTCGATTATCGATGAAC
TTCCACCGGGAAGAACGCCGGTTACCACAGTTGCAATTTCCGAGCAGCGTCGAGATGAGGTGATCGATCGAGTCAGACAA
GCCGCCATTAACGACAAGCGCCAAACTTACTGGGTATGCACCTTAATCGAAGAGTCTGAAGTACTCGAATGCCAAGCTGC
AGAAGACACGGCAGAAGAACTTAAACGCGTTCTGCCCGAGTTAAAGGTTGGCTTAGTTCATGGTCGTATGAAGCCTGCGG
AGAAGCAGCAGATCATGGCCGACTTTAAAGCAGGTGAGCTAAATCTATTAGTTGCCACTACAGTGATTGAGGTCGGTGTT
GATGTGCCCAATGCCAGTTTGATGATCATCGAAAACCCCGAACGTTTAGGCTTAGCACAGCTGCATCAGCTTAGAGGCCG
CGTTGGCCGTGGCGCAGTGGCCAGCCACTGCGTGCTGCTATACAAGCCGCCGCTATCTGCAACAGCCACCAAGAGGCTCG
GCGTACTCAGGCAGAGTAATGACGGCTTTGTGATTGCTCAGCAAGACTTGGAGATCCGTGGACCAGGTGAAGTATTAGGC
ACCAAACAGACTGGCATCGCCGATATGAAGATTGCCGACCTGATGCGCGATGAAGCCCTTATTCCTCATGTGCAGAAACT
GGCTGCACATGTTATGCAGCAGGCACCTACGAGTGTCGATGCCATTATTGAGCGCTGGCTTGGCGATAGAGAGCAATTCG
TACAAGCGTAA

Upstream 100 bases:

>100_bases
TGCAAATTATACGTTAGGCCTTTTTTGTTTTATATACACTGTTATCATCAGATTTGCGTAAACCGATATCTCTGATAATA
TATGTATAAATTTACAGTGT

Downstream 100 bases:

>100_bases
AGTGCTAATTTTGCCGCTTTTTGAAATTAAATATTCTTAATAGAGCTTCTGCCTATAGACAATCTGCTCGATTTTTGCAG
AATGGATTGAAGCTATACTT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 695

Protein sequence:

>696_residues
MSANRLQRLDLVPITDLKGVANKMAERLAKLSITTVQDLLFHLPLRYEDRTQVYPIASLYPGSYGTIEAVIQSSQIIQGR
KRMLTCTVRDDTGSLTLRFFNFSVAQRNGLEIGMTIRAYGEIRRGKHFAEIIHPEYKLISPGEDLQLSDTLTPVYPTTEG
LKQASWIKLTEQALAMLDNGGLQELLPPNLQPNNLDLKQALQILHRPNNQVSLFELEQGTHPAQQRLIQEELLAHNLSML
RLRQRSNRDKAVSMHATGQLLNPFLASLPFKPTGAQQRVVADITQDLAKHEPMMRLVQGDVGSGKTLIAALAALQAIESG
YQVAMMAPTELLAEQHALNFSSWFEPLGLKVGWLAGKLKGKARAQSLADIESGDAHIVIGTHAIFQEQVVFNKLALIIID
EQHRFGVHQRLGLREKGISQGFHPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPVTTVAISEQRRDEVIDRVRQ
AAINDKRQTYWVCTLIEESEVLECQAAEDTAEELKRVLPELKVGLVHGRMKPAEKQQIMADFKAGELNLLVATTVIEVGV
DVPNASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKPPLSATATKRLGVLRQSNDGFVIAQQDLEIRGPGEVLG
TKQTGIADMKIADLMRDEALIPHVQKLAAHVMQQAPTSVDAIIERWLGDREQFVQA

Sequences:

>Translated_696_residues
MSANRLQRLDLVPITDLKGVANKMAERLAKLSITTVQDLLFHLPLRYEDRTQVYPIASLYPGSYGTIEAVIQSSQIIQGR
KRMLTCTVRDDTGSLTLRFFNFSVAQRNGLEIGMTIRAYGEIRRGKHFAEIIHPEYKLISPGEDLQLSDTLTPVYPTTEG
LKQASWIKLTEQALAMLDNGGLQELLPPNLQPNNLDLKQALQILHRPNNQVSLFELEQGTHPAQQRLIQEELLAHNLSML
RLRQRSNRDKAVSMHATGQLLNPFLASLPFKPTGAQQRVVADITQDLAKHEPMMRLVQGDVGSGKTLIAALAALQAIESG
YQVAMMAPTELLAEQHALNFSSWFEPLGLKVGWLAGKLKGKARAQSLADIESGDAHIVIGTHAIFQEQVVFNKLALIIID
EQHRFGVHQRLGLREKGISQGFHPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPVTTVAISEQRRDEVIDRVRQ
AAINDKRQTYWVCTLIEESEVLECQAAEDTAEELKRVLPELKVGLVHGRMKPAEKQQIMADFKAGELNLLVATTVIEVGV
DVPNASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKPPLSATATKRLGVLRQSNDGFVIAQQDLEIRGPGEVLG
TKQTGIADMKIADLMRDEALIPHVQKLAAHVMQQAPTSVDAIIERWLGDREQFVQA
>Mature_695_residues
SANRLQRLDLVPITDLKGVANKMAERLAKLSITTVQDLLFHLPLRYEDRTQVYPIASLYPGSYGTIEAVIQSSQIIQGRK
RMLTCTVRDDTGSLTLRFFNFSVAQRNGLEIGMTIRAYGEIRRGKHFAEIIHPEYKLISPGEDLQLSDTLTPVYPTTEGL
KQASWIKLTEQALAMLDNGGLQELLPPNLQPNNLDLKQALQILHRPNNQVSLFELEQGTHPAQQRLIQEELLAHNLSMLR
LRQRSNRDKAVSMHATGQLLNPFLASLPFKPTGAQQRVVADITQDLAKHEPMMRLVQGDVGSGKTLIAALAALQAIESGY
QVAMMAPTELLAEQHALNFSSWFEPLGLKVGWLAGKLKGKARAQSLADIESGDAHIVIGTHAIFQEQVVFNKLALIIIDE
QHRFGVHQRLGLREKGISQGFHPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPVTTVAISEQRRDEVIDRVRQA
AINDKRQTYWVCTLIEESEVLECQAAEDTAEELKRVLPELKVGLVHGRMKPAEKQQIMADFKAGELNLLVATTVIEVGVD
VPNASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKPPLSATATKRLGVLRQSNDGFVIAQQDLEIRGPGEVLGT
KQTGIADMKIADLMRDEALIPHVQKLAAHVMQQAPTSVDAIIERWLGDREQFVQA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=688, Percent_Identity=67.0058139534884, Blast_Score=911, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=390, Percent_Identity=37.9487179487179, Blast_Score=239, Evalue=3e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77165; Mature: 77034

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANRLQRLDLVPITDLKGVANKMAERLAKLSITTVQDLLFHLPLRYEDRTQVYPIASLY
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHCC
PGSYGTIEAVIQSSQIIQGRKRMLTCTVRDDTGSLTLRFFNFSVAQRNGLEIGMTIRAYG
CCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEEEEEECCCCCCEEEEEEEEHH
EIRRGKHFAEIIHPEYKLISPGEDLQLSDTLTPVYPTTEGLKQASWIKLTEQALAMLDNG
HHHCCCHHHHHHCCCCEEECCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
GLQELLPPNLQPNNLDLKQALQILHRPNNQVSLFELEQGTHPAQQRLIQEELLAHNLSML
CHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
RLRQRSNRDKAVSMHATGQLLNPFLASLPFKPTGAQQRVVADITQDLAKHEPMMRLVQGD
HHHHHCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCC
VGSGKTLIAALAALQAIESGYQVAMMAPTELLAEQHALNFSSWFEPLGLKVGWLAGKLKG
CCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCHHHHHHHHCCEEEEHHHHHCC
KARAQSLADIESGDAHIVIGTHAIFQEQVVFNKLALIIIDEQHRFGVHQRLGLREKGISQ
HHHHHHHHHCCCCCEEEEEECHHHHHHHHHHCCEEEEEECCCHHCCHHHHCCCHHHHHCC
GFHPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPVTTVAISEQRRDEVIDRVRQ
CCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHH
AAINDKRQTYWVCTLIEESEVLECQAAEDTAEELKRVLPELKVGLVHGRMKPAEKQQIMA
HHHCCCCCEEEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
DFKAGELNLLVATTVIEVGVDVPNASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLL
HCCCCCEEEEEEEEHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCHHHCEEEE
YKPPLSATATKRLGVLRQSNDGFVIAQQDLEIRGPGEVLGTKQTGIADMKIADLMRDEAL
ECCCCCHHHHHHHHHEEECCCCEEEEECCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
IPHVQKLAAHVMQQAPTSVDAIIERWLGDREQFVQA
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCC
>Mature Secondary Structure 
SANRLQRLDLVPITDLKGVANKMAERLAKLSITTVQDLLFHLPLRYEDRTQVYPIASLY
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHCC
PGSYGTIEAVIQSSQIIQGRKRMLTCTVRDDTGSLTLRFFNFSVAQRNGLEIGMTIRAYG
CCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEEEEEECCCCCCEEEEEEEEHH
EIRRGKHFAEIIHPEYKLISPGEDLQLSDTLTPVYPTTEGLKQASWIKLTEQALAMLDNG
HHHCCCHHHHHHCCCCEEECCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
GLQELLPPNLQPNNLDLKQALQILHRPNNQVSLFELEQGTHPAQQRLIQEELLAHNLSML
CHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
RLRQRSNRDKAVSMHATGQLLNPFLASLPFKPTGAQQRVVADITQDLAKHEPMMRLVQGD
HHHHHCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCC
VGSGKTLIAALAALQAIESGYQVAMMAPTELLAEQHALNFSSWFEPLGLKVGWLAGKLKG
CCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCHHHHHHHHCCEEEEHHHHHCC
KARAQSLADIESGDAHIVIGTHAIFQEQVVFNKLALIIIDEQHRFGVHQRLGLREKGISQ
HHHHHHHHHCCCCCEEEEEECHHHHHHHHHHCCEEEEEECCCHHCCHHHHCCCHHHHHCC
GFHPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPVTTVAISEQRRDEVIDRVRQ
CCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHH
AAINDKRQTYWVCTLIEESEVLECQAAEDTAEELKRVLPELKVGLVHGRMKPAEKQQIMA
HHHCCCCCEEEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
DFKAGELNLLVATTVIEVGVDVPNASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLL
HCCCCCEEEEEEEEHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCHHHCEEEE
YKPPLSATATKRLGVLRQSNDGFVIAQQDLEIRGPGEVLGTKQTGIADMKIADLMRDEAL
ECCCCCHHHHHHHHHEEECCCCEEEEECCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
IPHVQKLAAHVMQQAPTSVDAIIERWLGDREQFVQA
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]