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The map label for this gene is fabZ

Identifier: 16752389

GI number: 16752389

Start: 107610

End: 108071

Strand: Direct

Name: fabZ

Synonym: CP0096

Alternate gene names: 16752389

Gene position: 107610-108071 (Clockwise)

Preceding gene: 16752388

Following gene: 16752390

Centisome position: 8.75

GC content: 40.26

Gene sequence:

>462_bases
ATGAATCAACCCTCTGTCATCAAATTACGCGAATTATTAGATTTACTCCCCCACAGATATCCTTTTTTATTAGTGGATAA
AGTTTTATCTTATGACATCGAGGCTCGCAGTATCACGGCACAAAAAAATGTCACAATAAATGAGCCTTTTTTTATGGGGC
ATTTTCCTAACGCGCCTATTATGCCTGGAGTCTTGATATTAGAAGCTTTGGCCCAAGCTGCTGGTGTATTGATAGGCTTA
GTTCTAGAAAATGATAGGAATAAGCGTATCGCATTATTTTTAGGGATACAGAAAGCTAAGTTTCGTCAAGCTGTTCGCCC
TGGAGATGTACTTACCCTGCAAGCAGATTTTTCTTTAATATCATCGAAAGGAGGTAAAGCTTGGGCACAGGCGCGTGTAG
ATTCACAGCTAGTCACTGAAGCAGAGCTGAGCTTTGCTCTGGTAGATAAGGAATCCATATAA

Upstream 100 bases:

>100_bases
CTTTTGTTGCGCATGTATTAGCTGTCGGCTCCGGCCACTCCTCCAATATTGCTTTTGGTAAAAAAATTTTGGAAGCATTA
GAACTATAAAGAAAGAATAA

Downstream 100 bases:

>100_bases
TCACGGAGAAACATGGCGAGCATTCACCCAACTGCAATTATCGAGCCAGGAGCTAAAATTGGAAAGGATGTTGTTATTGA
ACCGTACGTTGTTATAAAAG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MNQPSVIKLRELLDLLPHRYPFLLVDKVLSYDIEARSITAQKNVTINEPFFMGHFPNAPIMPGVLILEALAQAAGVLIGL
VLENDRNKRIALFLGIQKAKFRQAVRPGDVLTLQADFSLISSKGGKAWAQARVDSQLVTEAELSFALVDKESI

Sequences:

>Translated_153_residues
MNQPSVIKLRELLDLLPHRYPFLLVDKVLSYDIEARSITAQKNVTINEPFFMGHFPNAPIMPGVLILEALAQAAGVLIGL
VLENDRNKRIALFLGIQKAKFRQAVRPGDVLTLQADFSLISSKGGKAWAQARVDSQLVTEAELSFALVDKESI
>Mature_153_residues
MNQPSVIKLRELLDLLPHRYPFLLVDKVLSYDIEARSITAQKNVTINEPFFMGHFPNAPIMPGVLILEALAQAAGVLIGL
VLENDRNKRIALFLGIQKAKFRQAVRPGDVLTLQADFSLISSKGGKAWAQARVDSQLVTEAELSFALVDKESI

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=141, Percent_Identity=43.9716312056738, Blast_Score=123, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_CHLPN (Q9Z7Q3)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   D72051
- PIR:   H86571
- RefSeq:   NP_224847.1
- RefSeq:   NP_300707.1
- RefSeq:   NP_444648.1
- RefSeq:   NP_876949.1
- ProteinModelPortal:   Q9Z7Q3
- SMR:   Q9Z7Q3
- GeneID:   1467356
- GeneID:   895281
- GeneID:   919412
- GeneID:   963020
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0096
- KEGG:   cpn:CPn0651
- KEGG:   cpt:CpB0677
- TIGR:   CP_0096
- HOGENOM:   HBG433282
- OMA:   MEKININ
- PhylomeDB:   Q9Z7Q3
- ProtClustDB:   PRK00006
- BioCyc:   CPNE115711:CP_0096-MONOMER
- BioCyc:   CPNE115713:CPN0651-MONOMER
- BioCyc:   CPNE138677:CPJ0651-MONOMER
- BioCyc:   CPNE182082:CPB0677-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16925; Mature: 16925

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: ACT_SITE 54-54

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQPSVIKLRELLDLLPHRYPFLLVDKVLSYDIEARSITAQKNVTINEPFFMGHFPNAPI
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHEEECCCCEEECCCEEECCCCCCCC
MPGVLILEALAQAAGVLIGLVLENDRNKRIALFLGIQKAKFRQAVRPGDVLTLQADFSLI
CHHHHHHHHHHHHHHHEEEEEEECCCCCEEEEEEECCHHHHHHHCCCCCEEEEEECHHHH
SSKGGKAWAQARVDSQLVTEAELSFALVDKESI
HCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCC
>Mature Secondary Structure
MNQPSVIKLRELLDLLPHRYPFLLVDKVLSYDIEARSITAQKNVTINEPFFMGHFPNAPI
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHEEECCCCEEECCCEEECCCCCCCC
MPGVLILEALAQAAGVLIGLVLENDRNKRIALFLGIQKAKFRQAVRPGDVLTLQADFSLI
CHHHHHHHHHHHHHHHEEEEEEECCCCCEEEEEEECCHHHHHHHCCCCCEEEEEECHHHH
SSKGGKAWAQARVDSQLVTEAELSFALVDKESI
HCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362