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The map label for this gene is coaE [H]

Identifier: 167040778

GI number: 167040778

Start: 2158493

End: 2159089

Strand: Reverse

Name: coaE [H]

Synonym: Teth514_2155

Alternate gene names: 167040778

Gene position: 2159089-2158493 (Counterclockwise)

Preceding gene: 167040779

Following gene: 167040777

Centisome position: 87.87

GC content: 31.49

Gene sequence:

>597_bases
ATGCAAGTAATTGGACTGACTGGTGGCATTGCGTCTGGGAAAAGCACTGTTTCTAAGCTTTTAAAGAAGATGGGGGCTGT
GGTTATTGATGCAGATATCGTGTCGAGAGAAATAATGGTAAAGGGAACAGAAGCATATAATAAAATTGTAGAATATTTTG
GCAGAGAAATTTTAAAGGAGGACGGAGAAATTGACAGAAAGAAATTAGGTAATATTGTGTTTGCTGACAGAAGGAAGCTT
AAAAAATTAAATGAAATTACTCATCCTATAATAATAGAACGAATAAAAGAAAAAATAGAAGAAGAAAGAAAAAAGAATCA
GCAAAAGGCTATTGTATTAGACGCAGCTCTTTTAATTGAAATGAAACTTTATAAAATGGTAGATGAAGTTTGGCTAGTAG
TAGTAGATTCAAAAACTCAAATAAAGAGGGTTATGGAAAGGGATAAACTTTCTTACAAAGACGCGTTAAATCGTATAAAA
AGTCAAATGCCTCTGGATGAAAAAATAAGATACGCAGATTTTATAATAAACAATAGTAAGGATTTTAAAGCTATTGAAAA
ACAAGTTACACTATTTTGGGGAAGATTTGCAACATAA

Upstream 100 bases:

>100_bases
CTCAAAGATAATATGGAAAATGTAGTACAATTAAAAGTTCCCCTTGTAGTGGAAATTGGAGTAGGACCCAATTGGTTTTT
AGCCAAGTGAGGTGTACAAA

Downstream 100 bases:

>100_bases
ATCATGATATCGGAGGAGTTACTTTGAGAAAAAAAGTTGCGGTAATATTTTTGATACTACTAGGTCTTTTGTTTACTTAC
GAGTTAAATACTTATTATTT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MQVIGLTGGIASGKSTVSKLLKKMGAVVIDADIVSREIMVKGTEAYNKIVEYFGREILKEDGEIDRKKLGNIVFADRRKL
KKLNEITHPIIIERIKEKIEEERKKNQQKAIVLDAALLIEMKLYKMVDEVWLVVVDSKTQIKRVMERDKLSYKDALNRIK
SQMPLDEKIRYADFIINNSKDFKAIEKQVTLFWGRFAT

Sequences:

>Translated_198_residues
MQVIGLTGGIASGKSTVSKLLKKMGAVVIDADIVSREIMVKGTEAYNKIVEYFGREILKEDGEIDRKKLGNIVFADRRKL
KKLNEITHPIIIERIKEKIEEERKKNQQKAIVLDAALLIEMKLYKMVDEVWLVVVDSKTQIKRVMERDKLSYKDALNRIK
SQMPLDEKIRYADFIINNSKDFKAIEKQVTLFWGRFAT
>Mature_198_residues
MQVIGLTGGIASGKSTVSKLLKKMGAVVIDADIVSREIMVKGTEAYNKIVEYFGREILKEDGEIDRKKLGNIVFADRRKL
KKLNEITHPIIIERIKEKIEEERKKNQQKAIVLDAALLIEMKLYKMVDEVWLVVVDSKTQIKRVMERDKLSYKDALNRIK
SQMPLDEKIRYADFIINNSKDFKAIEKQVTLFWGRFAT

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=197, Percent_Identity=42.1319796954315, Blast_Score=146, Evalue=1e-35,
Organism=Homo sapiens, GI191252795, Length=197, Percent_Identity=42.1319796954315, Blast_Score=146, Evalue=1e-35,
Organism=Homo sapiens, GI110227607, Length=194, Percent_Identity=35.5670103092784, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI110227605, Length=194, Percent_Identity=35.5670103092784, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI110227603, Length=194, Percent_Identity=35.5670103092784, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI110227601, Length=194, Percent_Identity=35.5670103092784, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI205277394, Length=194, Percent_Identity=35.5670103092784, Blast_Score=129, Evalue=1e-30,
Organism=Escherichia coli, GI1786292, Length=194, Percent_Identity=30.4123711340206, Blast_Score=107, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17554944, Length=192, Percent_Identity=36.9791666666667, Blast_Score=121, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI25143409, Length=188, Percent_Identity=35.6382978723404, Blast_Score=100, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6320402, Length=194, Percent_Identity=38.1443298969072, Blast_Score=119, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24658602, Length=192, Percent_Identity=38.0208333333333, Blast_Score=141, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24644728, Length=180, Percent_Identity=40, Blast_Score=130, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22888; Mature: 22888

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVIGLTGGIASGKSTVSKLLKKMGAVVIDADIVSREIMVKGTEAYNKIVEYFGREILKE
CEEEEECCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHHEECHHHHHHHHHHHHHHHHHC
DGEIDRKKLGNIVFADRRKLKKLNEITHPIIIERIKEKIEEERKKNQQKAIVLDAALLIE
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MKLYKMVDEVWLVVVDSKTQIKRVMERDKLSYKDALNRIKSQMPLDEKIRYADFIINNSK
HHHHHHHHHHHEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCH
DFKAIEKQVTLFWGRFAT
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQVIGLTGGIASGKSTVSKLLKKMGAVVIDADIVSREIMVKGTEAYNKIVEYFGREILKE
CEEEEECCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHHEECHHHHHHHHHHHHHHHHHC
DGEIDRKKLGNIVFADRRKLKKLNEITHPIIIERIKEKIEEERKKNQQKAIVLDAALLIE
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MKLYKMVDEVWLVVVDSKTQIKRVMERDKLSYKDALNRIKSQMPLDEKIRYADFIINNSK
HHHHHHHHHHHEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCH
DFKAIEKQVTLFWGRFAT
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]