Click here to switch to the map view.

The map label for this gene is trpGD [H]

Identifier: 167040499

GI number: 167040499

Start: 1882970

End: 1883557

Strand: Reverse

Name: trpGD [H]

Synonym: Teth514_1868

Alternate gene names: 167040499

Gene position: 1883557-1882970 (Counterclockwise)

Preceding gene: 167040500

Following gene: 167040498

Centisome position: 76.65

GC content: 32.48

Gene sequence:

>588_bases
ATGATTCTGATTATAGATAATTACGATTCCTTTACCTATAATCTTTATCAATATGTGGGAGAAATGAACAAAGAAATATT
TGTAATAAGAAATGATGAAATGGATATTGAAGAGATTGAAAAACTGAATCCTGAGAAAATTATATTATCACCTGGACCAG
GAAGACCTGAAAATGCAGGCATATGCGTTGATGTCATTAAAAGTTTAGGGGATAAAATTCCAATATTAGGAATATGTCTT
GGCCATCAAGCGATTGGATATGCATATGGTGCAAAAATTGTAAAAGCAGATAAGATAATGCATGGCAAAACTTCTCTCGT
ATTTCACGAAGGTGAAAAAATATTTAAAGATATTAAGAATCCTATAGAGGCAATGAGATATCACTCTCTTGTTATAGATA
GACAAACTCTTCCAAGAAATTTAGAAATTACAGCCTATACAGAGGAAGGAGTGATTATGGGAGTAAGGCATAATAAATAC
CCTGTATATGGTTTACAGTTTCATCCAGAGTCTATCTTGACAGAGCAGGGTAAAGAAATTTTGAGAAATTTTTTGGAGGT
GGGATACCATGTTACAAGAAGCTATTAA

Upstream 100 bases:

>100_bases
CTTACGTTCAAGCGGGAGCAGGCATTGTATATGATTCAATTCCTGAGATGGAATACTGTGAAACTTTAAATAAGGCAATG
GCTCTTAAGGAGGTTCTTTG

Downstream 100 bases:

>100_bases
AAAAATTGTTTCAAAAGAGAACCTTGAAGAGAGAGAAGCTTATGCTGTTATGAATGAAATTATGAGTGGTAATGCAACTC
CTTCTTTAATAGGGGGTATA

Product: glutamine amidotransferase of anthranilate synthase

Products: NA

Alternate protein names: Glutamine amidotransferase; Anthranilate phosphoribosyltransferase [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MILIIDNYDSFTYNLYQYVGEMNKEIFVIRNDEMDIEEIEKLNPEKIILSPGPGRPENAGICVDVIKSLGDKIPILGICL
GHQAIGYAYGAKIVKADKIMHGKTSLVFHEGEKIFKDIKNPIEAMRYHSLVIDRQTLPRNLEITAYTEEGVIMGVRHNKY
PVYGLQFHPESILTEQGKEILRNFLEVGYHVTRSY

Sequences:

>Translated_195_residues
MILIIDNYDSFTYNLYQYVGEMNKEIFVIRNDEMDIEEIEKLNPEKIILSPGPGRPENAGICVDVIKSLGDKIPILGICL
GHQAIGYAYGAKIVKADKIMHGKTSLVFHEGEKIFKDIKNPIEAMRYHSLVIDRQTLPRNLEITAYTEEGVIMGVRHNKY
PVYGLQFHPESILTEQGKEILRNFLEVGYHVTRSY
>Mature_195_residues
MILIIDNYDSFTYNLYQYVGEMNKEIFVIRNDEMDIEEIEKLNPEKIILSPGPGRPENAGICVDVIKSLGDKIPILGICL
GHQAIGYAYGAKIVKADKIMHGKTSLVFHEGEKIFKDIKNPIEAMRYHSLVIDRQTLPRNLEITAYTEEGVIMGVRHNKY
PVYGLQFHPESILTEQGKEILRNFLEVGYHVTRSY

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=52.4324324324324, Blast_Score=229, Evalue=8e-62,
Organism=Escherichia coli, GI1787517, Length=187, Percent_Identity=43.3155080213904, Blast_Score=154, Evalue=3e-39,
Organism=Escherichia coli, GI1786215, Length=143, Percent_Identity=34.965034965035, Blast_Score=83, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322638, Length=188, Percent_Identity=47.3404255319149, Blast_Score=192, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6324361, Length=212, Percent_Identity=27.3584905660377, Blast_Score=81, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323873, Length=157, Percent_Identity=29.9363057324841, Blast_Score=72, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281365319, Length=114, Percent_Identity=30.7017543859649, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase; PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =4.1.3.27; =2.4.2.18 [H]

Molecular weight: Translated: 22316; Mature: 22316

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILIIDNYDSFTYNLYQYVGEMNKEIFVIRNDEMDIEEIEKLNPEKIILSPGPGRPENAG
CEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCCCEEEECCCCCCCCCCC
ICVDVIKSLGDKIPILGICLGHQAIGYAYGAKIVKADKIMHGKTSLVFHEGEKIFKDIKN
HHHHHHHHCCCCCCEEEEEECCHHHHHHHCCEEEEHHHEECCCEEEEEECCHHHHHHHHH
PIEAMRYHSLVIDRQTLPRNLEITAYTEEGVIMGVRHNKYPVYGLQFHPESILTEQGKEI
HHHHHHHHHHEEECCCCCCCEEEEEEECCCEEEEEECCCCCEEEEEECCHHHHHHHHHHH
LRNFLEVGYHVTRSY
HHHHHHHCHHEECCC
>Mature Secondary Structure
MILIIDNYDSFTYNLYQYVGEMNKEIFVIRNDEMDIEEIEKLNPEKIILSPGPGRPENAG
CEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCCCEEEECCCCCCCCCCC
ICVDVIKSLGDKIPILGICLGHQAIGYAYGAKIVKADKIMHGKTSLVFHEGEKIFKDIKN
HHHHHHHHCCCCCCEEEEEECCHHHHHHHCCEEEEHHHEECCCEEEEEECCHHHHHHHHH
PIEAMRYHSLVIDRQTLPRNLEITAYTEEGVIMGVRHNKYPVYGLQFHPESILTEQGKEI
HHHHHHHHHHEEECCCCCCCEEEEEEECCCEEEEEECCCCCEEEEEECCHHHHHHHHHHH
LRNFLEVGYHVTRSY
HHHHHHHCHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685830; 10360571; 7556082 [H]