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The map label for this gene is trpD

Identifier: 167040498

GI number: 167040498

Start: 1881973

End: 1882989

Strand: Reverse

Name: trpD

Synonym: Teth514_1867

Alternate gene names: 167040498

Gene position: 1882989-1881973 (Counterclockwise)

Preceding gene: 167040499

Following gene: 167040497

Centisome position: 76.63

GC content: 37.27

Gene sequence:

>1017_bases
ATGTTACAAGAAGCTATTAAAAAAATTGTTTCAAAAGAGAACCTTGAAGAGAGAGAAGCTTATGCTGTTATGAATGAAAT
TATGAGTGGTAATGCAACTCCTTCTTTAATAGGGGGTATATTAATAGGACTCCGATTAAAAGGGGAAAGTGTAGAAGAAA
TAACAGGTTTTGCAAAGGCAATGAGAGATAACGCCATAAAATTAGAACTTGCTTCGGATTATGTAATAGATACTTGTGGT
ACAGGTGGCGATGGTGGGAAGACATTCAATATTTCAACGGCAGTGGCGATAATTGCCTCTGCTGCAGGAGTAAAAGTTGC
AAAACACGGCAACAGAGCTGTTTCCAGCAAAAGCGGAAGTGCAGATGTTTTGATGGAATTGGGATTTGACATTGAAATGG
TGCCAGAAAAAACAAAAAGATTAATTGAAGAAAAGGGTATGGGATTTTTGTTTGCGCCCAAATATCACGTCGCAATGAAA
AACGTAGCAGGCATAAGAAAAGAGTTAGGCACAAGAACGGTATTTAATGTTTTAGGACCATTGACAAATCCCGCATTTGT
AAAAGGACAGGTATTAGGAGTTTACGATAAAGAATTGACTCATCCTCTCGCTGAAGTACTTTTAAGATTGGGAACTGAAA
AGGCTATGGTGGTCCACGGCTTTGATGGCCTTGATGAAATAACTACTACTTCTCCTACTTTTGTCAGTGAAGTAAAAGAA
GGCAAAGTCATTGATTATGTGATAGACCCAGAGGATTACGGTATCCCTTATGCAAAACTTGAAGATTTAGAAGGCAAAGA
TGCAAAAGAGAATGCTCAAATAATCTTAAACATCTTAAAAGGTGAAAAAGGGCCTAAAAGAGATATAGTCGTTTTAAACG
CAGCAGCAGCCTTATATATAGGAAAAGTTGTGGAAGATTTAAAAGAGGGAATAAAAGTCGCAAATTATCTAATAGATACG
GGTTTAGCTCTTGATAAGCTTACAGAGATTTTGGAGTACCAAAGGAGGCTTAATTGA

Upstream 100 bases:

>100_bases
CATAATAAATACCCTGTATATGGTTTACAGTTTCATCCAGAGTCTATCTTGACAGAGCAGGGTAAAGAAATTTTGAGAAA
TTTTTTGGAGGTGGGATACC

Downstream 100 bases:

>100_bases
TGGTATTAGATGAGATTGTGAGACACAAAAAAAAGGAGGTGGAAGAGAAAAAAAGAATAAAGCCAGTAGAGGAACTAATT
AACGAAATTAAAGGAGGCTA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MLQEAIKKIVSKENLEEREAYAVMNEIMSGNATPSLIGGILIGLRLKGESVEEITGFAKAMRDNAIKLELASDYVIDTCG
TGGDGGKTFNISTAVAIIASAAGVKVAKHGNRAVSSKSGSADVLMELGFDIEMVPEKTKRLIEEKGMGFLFAPKYHVAMK
NVAGIRKELGTRTVFNVLGPLTNPAFVKGQVLGVYDKELTHPLAEVLLRLGTEKAMVVHGFDGLDEITTTSPTFVSEVKE
GKVIDYVIDPEDYGIPYAKLEDLEGKDAKENAQIILNILKGEKGPKRDIVVLNAAAALYIGKVVEDLKEGIKVANYLIDT
GLALDKLTEILEYQRRLN

Sequences:

>Translated_338_residues
MLQEAIKKIVSKENLEEREAYAVMNEIMSGNATPSLIGGILIGLRLKGESVEEITGFAKAMRDNAIKLELASDYVIDTCG
TGGDGGKTFNISTAVAIIASAAGVKVAKHGNRAVSSKSGSADVLMELGFDIEMVPEKTKRLIEEKGMGFLFAPKYHVAMK
NVAGIRKELGTRTVFNVLGPLTNPAFVKGQVLGVYDKELTHPLAEVLLRLGTEKAMVVHGFDGLDEITTTSPTFVSEVKE
GKVIDYVIDPEDYGIPYAKLEDLEGKDAKENAQIILNILKGEKGPKRDIVVLNAAAALYIGKVVEDLKEGIKVANYLIDT
GLALDKLTEILEYQRRLN
>Mature_338_residues
MLQEAIKKIVSKENLEEREAYAVMNEIMSGNATPSLIGGILIGLRLKGESVEEITGFAKAMRDNAIKLELASDYVIDTCG
TGGDGGKTFNISTAVAIIASAAGVKVAKHGNRAVSSKSGSADVLMELGFDIEMVPEKTKRLIEEKGMGFLFAPKYHVAMK
NVAGIRKELGTRTVFNVLGPLTNPAFVKGQVLGVYDKELTHPLAEVLLRLGTEKAMVVHGFDGLDEITTTSPTFVSEVKE
GKVIDYVIDPEDYGIPYAKLEDLEGKDAKENAQIILNILKGEKGPKRDIVVLNAAAALYIGKVVEDLKEGIKVANYLIDT
GLALDKLTEILEYQRRLN

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=330, Percent_Identity=37.8787878787879, Blast_Score=220, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6320561, Length=273, Percent_Identity=36.6300366300366, Blast_Score=148, Evalue=1e-36,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_THEP3 (B0K8T3)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001664882.1
- ProteinModelPortal:   B0K8T3
- SMR:   B0K8T3
- GeneID:   5873609
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_0890
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   PRK00188
- BioCyc:   TPSE340099:TETH39_0890-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36583; Mature: 36583

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQEAIKKIVSKENLEEREAYAVMNEIMSGNATPSLIGGILIGLRLKGESVEEITGFAKA
CHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEECCCCHHHHHHHHHH
MRDNAIKLELASDYVIDTCGTGGDGGKTFNISTAVAIIASAAGVKVAKHGNRAVSSKSGS
HHCCCEEEEECCCEEEECCCCCCCCCEEEEHHHHHHHHHHHCCCEEHHCCCCCCCCCCCC
ADVLMELGFDIEMVPEKTKRLIEEKGMGFLFAPKYHVAMKNVAGIRKELGTRTVFNVLGP
HHHHHHCCCCEEECCHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LTNPAFVKGQVLGVYDKELTHPLAEVLLRLGTEKAMVVHGFDGLDEITTTSPTFVSEVKE
CCCCCEECCEEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHCCCCCHHHHHHCC
GKVIDYVIDPEDYGIPYAKLEDLEGKDAKENAQIILNILKGEKGPKRDIVVLNAAAALYI
CCEEEEEECCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHH
GKVVEDLKEGIKVANYLIDTGLALDKLTEILEYQRRLN
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLQEAIKKIVSKENLEEREAYAVMNEIMSGNATPSLIGGILIGLRLKGESVEEITGFAKA
CHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEECCCCHHHHHHHHHH
MRDNAIKLELASDYVIDTCGTGGDGGKTFNISTAVAIIASAAGVKVAKHGNRAVSSKSGS
HHCCCEEEEECCCEEEECCCCCCCCCEEEEHHHHHHHHHHHCCCEEHHCCCCCCCCCCCC
ADVLMELGFDIEMVPEKTKRLIEEKGMGFLFAPKYHVAMKNVAGIRKELGTRTVFNVLGP
HHHHHHCCCCEEECCHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LTNPAFVKGQVLGVYDKELTHPLAEVLLRLGTEKAMVVHGFDGLDEITTTSPTFVSEVKE
CCCCCEECCEEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHCCCCCHHHHHHCC
GKVIDYVIDPEDYGIPYAKLEDLEGKDAKENAQIILNILKGEKGPKRDIVVLNAAAALYI
CCEEEEEECCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHH
GKVVEDLKEGIKVANYLIDTGLALDKLTEILEYQRRLN
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA