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The map label for this gene is clpP2 [H]

Identifier: 167039898

GI number: 167039898

Start: 1294127

End: 1294807

Strand: Direct

Name: clpP2 [H]

Synonym: Teth514_1253

Alternate gene names: 167039898

Gene position: 1294127-1294807 (Clockwise)

Preceding gene: 167039897

Following gene: 167039899

Centisome position: 52.67

GC content: 41.56

Gene sequence:

>681_bases
ATGAAGAAATTTTGGAATTGGGTTCGCGACACAGATACACAGACACGAACCCTCTATCTAAACGGTGCAATTGCCGAGGA
GAGTTGGTTTGAGGATGATGTTACCCCAGCTGCTTTTAGAGAAGAGCTAATGAGTGGTGAAGGAGACATAGTAGTTTGGA
TTAACTCTCCTGGTGGTGATTGTATTGCAGCATCTCAGATATACAACATGCTAATGGATTATAAAGGAAACGTCACTGTA
AAGATTGACGGTATTGCTGCATCAGCTGCTTCTGTCATCGCTATGGCAGGGACGGAAGTCTTAATGTCTCCTACCTCACT
GATGATGATCCATAATCCCTTTACCATAGCTATTGGCGATAGTGAGGAGATGCAAAAAGCAATCCAAATGCTTGATGAAG
TGAAAGAGAGCATCATCAATGCATATGAGCTTAAAACCGGCTTATCTAGAACAAGGTTGTCGCACCTGATGGATGCTGAA
ACTTGGCTAAACGCCAATAAGGCAGTTGAGCTTGGTTTTGCAGATGACATTATGTTCAAACCAGGAGAGAGTTCACTACA
AGACAGCTTTGTATTCAGCAGAAGAGCAGTGACCAATTCACTAATGAATAAACTTCAAAAACCAGTTGTAAAACAGTCAG
TAGAGCCGCTTTATGAGCGGCTTAATTTATTGAAATATTAG

Upstream 100 bases:

>100_bases
CAGAGCTTGGAGGAGATTTATATCTAATCAATGGCAATATGACCAAACTTGAAGATGCGGGTATTTTCGCAAATAAAGAA
GGATTGGAGGGAAAACCTGA

Downstream 100 bases:

>100_bases
GAGGAATAAAAATGAGTAAAATTCTTGAACTGCGTGAAAAACGCGCAAAAGCATGGGAAGCAGCAAAGGCATTTCTTGAT
TCAAAGCGTGGTAGTGATGG

Product: peptidase S14, ClpP

Products: NA

Alternate protein names: Endopeptidase Clp 2 [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKKFWNWVRDTDTQTRTLYLNGAIAEESWFEDDVTPAAFREELMSGEGDIVVWINSPGGDCIAASQIYNMLMDYKGNVTV
KIDGIAASAASVIAMAGTEVLMSPTSLMMIHNPFTIAIGDSEEMQKAIQMLDEVKESIINAYELKTGLSRTRLSHLMDAE
TWLNANKAVELGFADDIMFKPGESSLQDSFVFSRRAVTNSLMNKLQKPVVKQSVEPLYERLNLLKY

Sequences:

>Translated_226_residues
MKKFWNWVRDTDTQTRTLYLNGAIAEESWFEDDVTPAAFREELMSGEGDIVVWINSPGGDCIAASQIYNMLMDYKGNVTV
KIDGIAASAASVIAMAGTEVLMSPTSLMMIHNPFTIAIGDSEEMQKAIQMLDEVKESIINAYELKTGLSRTRLSHLMDAE
TWLNANKAVELGFADDIMFKPGESSLQDSFVFSRRAVTNSLMNKLQKPVVKQSVEPLYERLNLLKY
>Mature_226_residues
MKKFWNWVRDTDTQTRTLYLNGAIAEESWFEDDVTPAAFREELMSGEGDIVVWINSPGGDCIAASQIYNMLMDYKGNVTV
KIDGIAASAASVIAMAGTEVLMSPTSLMMIHNPFTIAIGDSEEMQKAIQMLDEVKESIINAYELKTGLSRTRLSHLMDAE
TWLNANKAVELGFADDIMFKPGESSLQDSFVFSRRAVTNSLMNKLQKPVVKQSVEPLYERLNLLKY

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Escherichia coli, GI1786641, Length=165, Percent_Identity=27.8787878787879, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 25292; Mature: 25292

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFWNWVRDTDTQTRTLYLNGAIAEESWFEDDVTPAAFREELMSGEGDIVVWINSPGGD
CCHHHHHHHCCCCCEEEEEEECEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCC
CIAASQIYNMLMDYKGNVTVKIDGIAASAASVIAMAGTEVLMSPTSLMMIHNPFTIAIGD
EEHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCHHHCCCCEEEEEECCEEEEECC
SEEMQKAIQMLDEVKESIINAYELKTGLSRTRLSHLMDAETWLNANKAVELGFADDIMFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEC
PGESSLQDSFVFSRRAVTNSLMNKLQKPVVKQSVEPLYERLNLLKY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKFWNWVRDTDTQTRTLYLNGAIAEESWFEDDVTPAAFREELMSGEGDIVVWINSPGGD
CCHHHHHHHCCCCCEEEEEEECEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCC
CIAASQIYNMLMDYKGNVTVKIDGIAASAASVIAMAGTEVLMSPTSLMMIHNPFTIAIGD
EEHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCHHHCCCCEEEEEECCEEEEECC
SEEMQKAIQMLDEVKESIINAYELKTGLSRTRLSHLMDAETWLNANKAVELGFADDIMFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEC
PGESSLQDSFVFSRRAVTNSLMNKLQKPVVKQSVEPLYERLNLLKY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]