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The map label for this gene is glpR [H]

Identifier: 167039729

GI number: 167039729

Start: 1115672

End: 1116427

Strand: Direct

Name: glpR [H]

Synonym: Teth514_1079

Alternate gene names: 167039729

Gene position: 1115672-1116427 (Clockwise)

Preceding gene: 167039728

Following gene: 167039730

Centisome position: 45.4

GC content: 33.47

Gene sequence:

>756_bases
ATGCTGGTTTCGACAAGGAGAGATAAAATCAAAGAAATCATTTTAAAAAAGAAAGCCGTTAAAGTCTCTGAGCTTTGTGA
GATTTTCAAAGTTTCTGATGAGACAATAAGAAGGGACTTAGAAGAATTAGAAAGACAAGGACTGGTAGAGAGAAACTATG
GAGGCGCAGTACTGAAAGAAAATATTATTATTCCTCCACTTGTCAAAAGATTTAAAGAGCACACAGAAGAAAAGCAAAAA
ATTGCTGCAAAAGCGGTAGGAGAAGTAAAAGAAGGAGATGTCATTTTTTTAGATGCAGGTTCTACTACTTATCACATAGC
CCGACTCCTTAAAAATTTTAATAACATAACTGTTGTGACAAATGCTTTAAACGTTGCTACAGAATTAGCTAATAATCCTA
ATATTAATCTTTTTATTACTGGTGGAAAATTAAAAACTGACAATCATTCAATGGTAGGCTTTGAAACACTAAATTGCATT
GGCAGATACAACATTGACATCTTGTTTTTAGGAACTGGTGGCATTTCTTTAGAAAAAGGGCTTACGACTTCTGATATTTT
TGAAGCCGAAGCTAAAAAAGCAATGATAAAATCAGCCAAGCGAGTAATTGTCGTGGCTGATAGTGGCAAATTTGGAAAAG
TTGCAATGGTGTCTTTTTGCACATTTGAAGATGTAGAAAAGATAATAACCTCTGGAGAACAAAACAAAGAGATAGTAGAG
GAATTAAAAAATTATGTAAAGATTGAAGTGGTATAG

Upstream 100 bases:

>100_bases
AAAACGGAATTTCCAACTTGAAACTGTGTTTTGTTTTTATTTACTTTTTAGGTTTTGAGCAAAATAAAAAACAAATTGAT
ATTTTTAGGAGTGGATGTAG

Downstream 100 bases:

>100_bases
AAAATTTAAAAGGAGAAGATTACTTAGGAGGCGTAAAAATGGGTGTTAAAATTGCTATTGTAAATTCCAGTAGTTTTGGT
AAGCATTTTCCTGAACATAT

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLVSTRRDKIKEIILKKKAVKVSELCEIFKVSDETIRRDLEELERQGLVERNYGGAVLKENIIIPPLVKRFKEHTEEKQK
IAAKAVGEVKEGDVIFLDAGSTTYHIARLLKNFNNITVVTNALNVATELANNPNINLFITGGKLKTDNHSMVGFETLNCI
GRYNIDILFLGTGGISLEKGLTTSDIFEAEAKKAMIKSAKRVIVVADSGKFGKVAMVSFCTFEDVEKIITSGEQNKEIVE
ELKNYVKIEVV

Sequences:

>Translated_251_residues
MLVSTRRDKIKEIILKKKAVKVSELCEIFKVSDETIRRDLEELERQGLVERNYGGAVLKENIIIPPLVKRFKEHTEEKQK
IAAKAVGEVKEGDVIFLDAGSTTYHIARLLKNFNNITVVTNALNVATELANNPNINLFITGGKLKTDNHSMVGFETLNCI
GRYNIDILFLGTGGISLEKGLTTSDIFEAEAKKAMIKSAKRVIVVADSGKFGKVAMVSFCTFEDVEKIITSGEQNKEIVE
ELKNYVKIEVV
>Mature_251_residues
MLVSTRRDKIKEIILKKKAVKVSELCEIFKVSDETIRRDLEELERQGLVERNYGGAVLKENIIIPPLVKRFKEHTEEKQK
IAAKAVGEVKEGDVIFLDAGSTTYHIARLLKNFNNITVVTNALNVATELANNPNINLFITGGKLKTDNHSMVGFETLNCI
GRYNIDILFLGTGGISLEKGLTTSDIFEAEAKKAMIKSAKRVIVVADSGKFGKVAMVSFCTFEDVEKIITSGEQNKEIVE
ELKNYVKIEVV

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=245, Percent_Identity=33.469387755102, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1789519, Length=229, Percent_Identity=33.6244541484716, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1789059, Length=229, Percent_Identity=39.3013100436681, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI87082344, Length=225, Percent_Identity=30.6666666666667, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1788069, Length=241, Percent_Identity=35.2697095435685, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789170, Length=234, Percent_Identity=31.6239316239316, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI226510968, Length=232, Percent_Identity=32.7586206896552, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1790753, Length=245, Percent_Identity=26.530612244898, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787540, Length=229, Percent_Identity=28.82096069869, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790635, Length=246, Percent_Identity=24.7967479674797, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1787063, Length=196, Percent_Identity=27.5510204081633, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27963; Mature: 27963

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVSTRRDKIKEIILKKKAVKVSELCEIFKVSDETIRRDLEELERQGLVERNYGGAVLKE
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NIIIPPLVKRFKEHTEEKQKIAAKAVGEVKEGDVIFLDAGSTTYHIARLLKNFNNITVVT
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEE
NALNVATELANNPNINLFITGGKLKTDNHSMVGFETLNCIGRYNIDILFLGTGGISLEKG
HHHHHHHHHCCCCCEEEEEECCEEECCCCCEECHHHHHHHEECCEEEEEEECCCCEECCC
LTTSDIFEAEAKKAMIKSAKRVIVVADSGKFGKVAMVSFCTFEDVEKIITSGEQNKEIVE
CCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHCCCCCHHHHH
ELKNYVKIEVV
HHHHHEEEEEC
>Mature Secondary Structure
MLVSTRRDKIKEIILKKKAVKVSELCEIFKVSDETIRRDLEELERQGLVERNYGGAVLKE
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NIIIPPLVKRFKEHTEEKQKIAAKAVGEVKEGDVIFLDAGSTTYHIARLLKNFNNITVVT
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEE
NALNVATELANNPNINLFITGGKLKTDNHSMVGFETLNCIGRYNIDILFLGTGGISLEKG
HHHHHHHHHCCCCCEEEEEECCEEECCCCCEECHHHHHHHEECCEEEEEEECCCCEECCC
LTTSDIFEAEAKKAMIKSAKRVIVVADSGKFGKVAMVSFCTFEDVEKIITSGEQNKEIVE
CCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHCCCCCHHHHH
ELKNYVKIEVV
HHHHHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]