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The map label for this gene is iolE [H]

Identifier: 167039725

GI number: 167039725

Start: 1111732

End: 1112481

Strand: Direct

Name: iolE [H]

Synonym: Teth514_1075

Alternate gene names: 167039725

Gene position: 1111732-1112481 (Clockwise)

Preceding gene: 167039724

Following gene: 167039726

Centisome position: 45.24

GC content: 32.53

Gene sequence:

>750_bases
ATGAGTATACCTATAGCACTTCAACTTTACACTTTGAGAGAGGAGACACAAAAAGATTTTATAGGTACTCTTGAAAAGGT
TGCGGAAATAGGATACGAAGGAGTGGAGTTTGCAGGATATGGCGGTTTAAAAGCATCAGAATTAAGAAAAACGCTTGATA
ATTTAGGATTAAAAGTTGCTGGTAGTCATGTAGGAATAGAATTACTTAAAAACAATCTTGAGGAAGTGATAGATTATAAC
CTTGAAATAGGCAATAAATACATCGTCTGTCCGTGGAATGAGTACAAGTCAAGAGAGGATTATATTGAAACAGCAAAGTT
GTTTAATAAAATAGGTGAAAAGTGTAGGGAAAAGGGACTTGAGTTTTGCTATCACAACCACAATCACGAATTTGAAATAT
ACGATGGAGAATATGGACTTGATATACTTTACAAAAATACAGATAAAGACCTTGTAAAAGCTGAAATCGATGCGTATTGG
GTTACATATGCGGGAGTTGACGCGGTAGAATATCTTAAAAAATTCTCCAATAGACTACCTTTAATTCACTTAAAAGACAT
GGATAAAGAGGACAGGTCTTTTACTGAAATAGGAAATGGAATTATCAATTTTAAAGAAGTAATAAAAATTGCAAAAGAAA
ATGGAGTTAAATGGTTAATTGTTGAACAGGATGTGTGTAAAAGACCTCCAATTGAAAGTGTGAAAATTAGTTTTGAAAAT
TTAAAAAAGATTTTAGAGGAGGAAATGTAG

Upstream 100 bases:

>100_bases
CTGAAGAAGGGGCAAAACTCATGGGAATAATAGACGGTGCCTATGAATCAGCTGAAAAAGGTAAGGAAATAGTTTTAGGT
TAAAGGGGGAAAAAATTAAA

Downstream 100 bases:

>100_bases
ATGTATTTAGGATTTTTAACAGTATGTCTTGGGAATATGCCTCTTAAAGAAAAAGCTAAGTGGGCAAGTGAAAATGGGTT
TAAATCACTGGAAATTGCCT

Product: xylose isomerase domain-containing protein

Products: NA

Alternate protein names: 2-keto-myo-inositol dehydratase; 2KMI dehydratase [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MSIPIALQLYTLREETQKDFIGTLEKVAEIGYEGVEFAGYGGLKASELRKTLDNLGLKVAGSHVGIELLKNNLEEVIDYN
LEIGNKYIVCPWNEYKSREDYIETAKLFNKIGEKCREKGLEFCYHNHNHEFEIYDGEYGLDILYKNTDKDLVKAEIDAYW
VTYAGVDAVEYLKKFSNRLPLIHLKDMDKEDRSFTEIGNGIINFKEVIKIAKENGVKWLIVEQDVCKRPPIESVKISFEN
LKKILEEEM

Sequences:

>Translated_249_residues
MSIPIALQLYTLREETQKDFIGTLEKVAEIGYEGVEFAGYGGLKASELRKTLDNLGLKVAGSHVGIELLKNNLEEVIDYN
LEIGNKYIVCPWNEYKSREDYIETAKLFNKIGEKCREKGLEFCYHNHNHEFEIYDGEYGLDILYKNTDKDLVKAEIDAYW
VTYAGVDAVEYLKKFSNRLPLIHLKDMDKEDRSFTEIGNGIINFKEVIKIAKENGVKWLIVEQDVCKRPPIESVKISFEN
LKKILEEEM
>Mature_248_residues
SIPIALQLYTLREETQKDFIGTLEKVAEIGYEGVEFAGYGGLKASELRKTLDNLGLKVAGSHVGIELLKNNLEEVIDYNL
EIGNKYIVCPWNEYKSREDYIETAKLFNKIGEKCREKGLEFCYHNHNHEFEIYDGEYGLDILYKNTDKDLVKAEIDAYWV
TYAGVDAVEYLKKFSNRLPLIHLKDMDKEDRSFTEIGNGIINFKEVIKIAKENGVKWLIVEQDVCKRPPIESVKISFENL
KKILEEEM

Specific function: Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D- (3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) [H]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolE/mocC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.44 [H]

Molecular weight: Translated: 28789; Mature: 28658

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIPIALQLYTLREETQKDFIGTLEKVAEIGYEGVEFAGYGGLKASELRKTLDNLGLKVA
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHCCEEEE
GSHVGIELLKNNLEEVIDYNLEIGNKYIVCPWNEYKSREDYIETAKLFNKIGEKCREKGL
CCHHHHHHHHHHHHHHHHCCEEECCEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHHCCH
EFCYHNHNHEFEIYDGEYGLDILYKNTDKDLVKAEIDAYWVTYAGVDAVEYLKKFSNRLP
HHHCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHEEEEECCHHHHHHHHHHHCCCC
LIHLKDMDKEDRSFTEIGNGIINFKEVIKIAKENGVKWLIVEQDVCKRPPIESVKISFEN
EEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEECHHHHCCCCCHHHEECHHH
LKKILEEEM
HHHHHHHCC
>Mature Secondary Structure 
SIPIALQLYTLREETQKDFIGTLEKVAEIGYEGVEFAGYGGLKASELRKTLDNLGLKVA
CCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHCCEEEE
GSHVGIELLKNNLEEVIDYNLEIGNKYIVCPWNEYKSREDYIETAKLFNKIGEKCREKGL
CCHHHHHHHHHHHHHHHHCCEEECCEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHHCCH
EFCYHNHNHEFEIYDGEYGLDILYKNTDKDLVKAEIDAYWVTYAGVDAVEYLKKFSNRLP
HHHCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHEEEEECCHHHHHHHHHHHCCCC
LIHLKDMDKEDRSFTEIGNGIINFKEVIKIAKENGVKWLIVEQDVCKRPPIESVKISFEN
EEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEECHHHHCCCCCHHHEECHHH
LKKILEEEM
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA