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The map label for this gene is yrbE [H]

Identifier: 167039645

GI number: 167039645

Start: 1024956

End: 1026113

Strand: Direct

Name: yrbE [H]

Synonym: Teth514_0993

Alternate gene names: 167039645

Gene position: 1024956-1026113 (Clockwise)

Preceding gene: 167039644

Following gene: 167039649

Centisome position: 41.71

GC content: 32.64

Gene sequence:

>1158_bases
ATGAGAAAAATAAAGGTTGGAATAATAGGTACGGGTTTTATAGGACCTGCACATATTGAAGCTTTGAGAAGATTAGGGTT
TATAGAAGTAGCAGCAATTGCAGATGTTAATCAAGAAATAGCAAAGCAAAAAGCAGAGTTATTAAATGTAGAAAAATATT
ATGGTGATTACAAAGAATTATTGAAAGATCCAGAAATAGAATCAGTTCATGTGTGTACTCCTAATTACCTCCATTATAAA
ATTGCTAAAGATGCTTTATTGGCAAACAAACATGTAATATGCGAAAAGCCTTTAGCTATGAATTCTTCTGAAGCTGACGA
ACTTATTAGAATTGCAAAAGAGAAAAAACTTGTGAATGCGGTACATTTTAATTTAAGATTTTATCCTTTAATGCATCATG
CAAAAAAAATGATAGAAGAAGGTGAATTAGGGCAGATTTTTGCAATAAATGGTTCATATCAGCAAGATTGGCTTTTTTAT
GATACAGATTTTAACTGGAGACTTTTGCCTGAATTTAGTGGAGATTCTAGGGCGGTTGCAGACATAGGTTCCCATTGGTT
GGATCTAATCGAATTTGTTACAGGAATTAAAGTAAATGAAGTGTGTGCGGATTTTGCAACATTTTATCCTATAAGGAAAA
AACCACTAAAACCTGTTGAAACCTATGCAGGGAAATTGTTAAGTCCAGAGGATTATGAAGAAGTAAAGATTGAGACTGAA
GATTATGCTACAGTACTCTTAAAATTTAATAATGGAGCACATGGATCAATGACTGTAAATCAGGTTGCAGCAGGACGAAA
AAATAGATTATATTTTGAGATTTACGGTTCTAAAAAGTCTATAAGTTGGGATTCAGAGAGACCTAATGAACTTTGGATTG
GAAGAAGAGATGGGACTAATGAAATTTTAATTAAAGACCCTTCGTTATTAAATCCTTATGCTAGAGAAATAACTAGTTTC
CCTGGAGGACATAACGAAGGTTTTCCTGATACTTCTAAACAGATGTTTAAAAAAGTTTACAAATATATACTTCAGGATGG
TCATCTTAAAGGAGAAACTCCTGATTTTCCAACTTTTGAAGATGGACGTCGCGAATTATTCTTATGTGAACAAATAGTAA
AGTCTGCAAAAGAAAATAAGTGGGTTGTAATTGAGTAA

Upstream 100 bases:

>100_bases
TCCTTATGCTGACATAAGGAAAGCAGAACTTGGAAATGATGCGGGAATAATTGGTGCAGCTATATTAGATTAAATTATGG
TAGAGGAGGAGATGTAAAAA

Downstream 100 bases:

>100_bases
AATCAAGTAGGAGGGAGGCGAATCATCCCTCCTACTTGATAAAATTTTTAAAATTACAAATTATACGCTATGCGAAAACC
TTCGTGAATGGCATCTATAA

Product: oxidoreductase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MRKIKVGIIGTGFIGPAHIEALRRLGFIEVAAIADVNQEIAKQKAELLNVEKYYGDYKELLKDPEIESVHVCTPNYLHYK
IAKDALLANKHVICEKPLAMNSSEADELIRIAKEKKLVNAVHFNLRFYPLMHHAKKMIEEGELGQIFAINGSYQQDWLFY
DTDFNWRLLPEFSGDSRAVADIGSHWLDLIEFVTGIKVNEVCADFATFYPIRKKPLKPVETYAGKLLSPEDYEEVKIETE
DYATVLLKFNNGAHGSMTVNQVAAGRKNRLYFEIYGSKKSISWDSERPNELWIGRRDGTNEILIKDPSLLNPYAREITSF
PGGHNEGFPDTSKQMFKKVYKYILQDGHLKGETPDFPTFEDGRRELFLCEQIVKSAKENKWVVIE

Sequences:

>Translated_385_residues
MRKIKVGIIGTGFIGPAHIEALRRLGFIEVAAIADVNQEIAKQKAELLNVEKYYGDYKELLKDPEIESVHVCTPNYLHYK
IAKDALLANKHVICEKPLAMNSSEADELIRIAKEKKLVNAVHFNLRFYPLMHHAKKMIEEGELGQIFAINGSYQQDWLFY
DTDFNWRLLPEFSGDSRAVADIGSHWLDLIEFVTGIKVNEVCADFATFYPIRKKPLKPVETYAGKLLSPEDYEEVKIETE
DYATVLLKFNNGAHGSMTVNQVAAGRKNRLYFEIYGSKKSISWDSERPNELWIGRRDGTNEILIKDPSLLNPYAREITSF
PGGHNEGFPDTSKQMFKKVYKYILQDGHLKGETPDFPTFEDGRRELFLCEQIVKSAKENKWVVIE
>Mature_385_residues
MRKIKVGIIGTGFIGPAHIEALRRLGFIEVAAIADVNQEIAKQKAELLNVEKYYGDYKELLKDPEIESVHVCTPNYLHYK
IAKDALLANKHVICEKPLAMNSSEADELIRIAKEKKLVNAVHFNLRFYPLMHHAKKMIEEGELGQIFAINGSYQQDWLFY
DTDFNWRLLPEFSGDSRAVADIGSHWLDLIEFVTGIKVNEVCADFATFYPIRKKPLKPVETYAGKLLSPEDYEEVKIETE
DYATVLLKFNNGAHGSMTVNQVAAGRKNRLYFEIYGSKKSISWDSERPNELWIGRRDGTNEILIKDPSLLNPYAREITSF
PGGHNEGFPDTSKQMFKKVYKYILQDGHLKGETPDFPTFEDGRRELFLCEQIVKSAKENKWVVIE

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Homo sapiens, GI7657212, Length=261, Percent_Identity=26.0536398467433, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI145693182, Length=186, Percent_Identity=28.494623655914, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789848, Length=112, Percent_Identity=35.7142857142857, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87081947, Length=209, Percent_Identity=29.6650717703349, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787574, Length=198, Percent_Identity=28.2828282828283, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87082405, Length=175, Percent_Identity=26.2857142857143, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323975, Length=293, Percent_Identity=25.938566552901, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920536, Length=212, Percent_Identity=28.3018867924528, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24581117, Length=145, Percent_Identity=33.7931034482759, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 44101; Mature: 44101

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIKVGIIGTGFIGPAHIEALRRLGFIEVAAIADVNQEIAKQKAELLNVEKYYGDYKEL
CCEEEEEEEEECCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKDPEIESVHVCTPNYLHYKIAKDALLANKHVICEKPLAMNSSEADELIRIAKEKKLVNA
HCCCCCCEEEEECCCCEEEEEHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHH
VHFNLRFYPLMHHAKKMIEEGELGQIFAINGSYQQDWLFYDTDFNWRLLPEFSGDSRAVA
EEECEEEHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCEEECCCCCCCCHHHH
DIGSHWLDLIEFVTGIKVNEVCADFATFYPIRKKPLKPVETYAGKLLSPEDYEEVKIETE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCEEEECC
DYATVLLKFNNGAHGSMTVNQVAAGRKNRLYFEIYGSKKSISWDSERPNELWIGRRDGTN
CEEEEEEEECCCCCCCEEHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCC
EILIKDPSLLNPYAREITSFPGGHNEGFPDTSKQMFKKVYKYILQDGHLKGETPDFPTFE
EEEEECCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
DGRRELFLCEQIVKSAKENKWVVIE
CCCHHHHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure
MRKIKVGIIGTGFIGPAHIEALRRLGFIEVAAIADVNQEIAKQKAELLNVEKYYGDYKEL
CCEEEEEEEEECCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKDPEIESVHVCTPNYLHYKIAKDALLANKHVICEKPLAMNSSEADELIRIAKEKKLVNA
HCCCCCCEEEEECCCCEEEEEHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHH
VHFNLRFYPLMHHAKKMIEEGELGQIFAINGSYQQDWLFYDTDFNWRLLPEFSGDSRAVA
EEECEEEHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCEEECCCCCCCCHHHH
DIGSHWLDLIEFVTGIKVNEVCADFATFYPIRKKPLKPVETYAGKLLSPEDYEEVKIETE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCEEEECC
DYATVLLKFNNGAHGSMTVNQVAAGRKNRLYFEIYGSKKSISWDSERPNELWIGRRDGTN
CEEEEEEEECCCCCCCEEHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCC
EILIKDPSLLNPYAREITSFPGGHNEGFPDTSKQMFKKVYKYILQDGHLKGETPDFPTFE
EEEEECCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
DGRRELFLCEQIVKSAKENKWVVIE
CCCHHHHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]