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The map label for this gene is glcK [H]

Identifier: 167039644

GI number: 167039644

Start: 1023990

End: 1024928

Strand: Direct

Name: glcK [H]

Synonym: Teth514_0992

Alternate gene names: 167039644

Gene position: 1023990-1024928 (Clockwise)

Preceding gene: 167039643

Following gene: 167039645

Centisome position: 41.67

GC content: 39.4

Gene sequence:

>939_bases
ATGAGAATTGGCGTTGACCTTGGAGGCACTAACATAGCTGTTGGATTAGTGGATGAAGAAGGACGTATAGTAGCTACAGA
TAGCAGACCGACAAAACCGGAAAGAGGTTATGAGGCGATTGCCAAAGACATAGCGGATATAGCTTTTGAACTTATTAAGA
GGAGTAATCTAAGTGTAAGTGACATTAAGTCAATGGGAATAGGAGTCCCGGGTGTAGCAGATAGCGAAAAAGGCATAGTA
ATACGAGCGGTGAATCTCTTTTGGACAAAAGTTCCCCTTGCAAAAGAAATAAGAAAATACATTGATTTGCCAATATATAT
GGGCAATGATGCAAATGTAGCGGCTTTGGCAGAGGCGATATTTGGCGCTGGTAAAGGCTCAAAGTCCTCTATCACGCTTA
CTTTAGGTACAGGAGTAGGATCTGGCTTTATTCTCGACGGCAAAATATACAACTGTGCTCATCATTTTGCACTTGAGCTT
GGACACATAGTGATAGGAGACAATGGTGTAAGGTGTAACTGTGGTAAGATTGGATGTTTGGAAACATATGCTTCAGCTAC
TGCTTTAATAAGAGAAGGGAAAAAAGCAGTAGAGAAGAATCCCAATTCTCTTATTTTAAAATTGGCAAATGGGGATATAG
AAAGCATAACAGCTAAAAATGTAATTGATGCTGCAAAGCAGTATGATGAGCAAGCGATGAGAATTTTCAATGATTATGTC
AAATACCTGGCTGTTGGAATTGTCAATGTCATAAACATGTTTGACCCTGAAGTGATAATATTGGGTGGCGGCGTTGCAAA
TACGGGAGATTTTCTCATAAAACCCCTCAAAAAAGAAGTGGCGGAAAATATTTTGTTTAAAGACCTTCCTTATGCTGACA
TAAGGAAAGCAGAACTTGGAAATGATGCGGGAATAATTGGTGCAGCTATATTAGATTAA

Upstream 100 bases:

>100_bases
CTAAAACAATTCATTGTATAATTTTACGAAACTTGCATTTCATGAGGTTAAATTTTCTTAGAAAATATAGCTAACAAAAA
TAATAAAGGTGATGAGAAGA

Downstream 100 bases:

>100_bases
ATTATGGTAGAGGAGGAGATGTAAAAAATGAGAAAAATAAAGGTTGGAATAATAGGTACGGGTTTTATAGGACCTGCACA
TATTGAAGCTTTGAGAAGAT

Product: ROK family glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MRIGVDLGGTNIAVGLVDEEGRIVATDSRPTKPERGYEAIAKDIADIAFELIKRSNLSVSDIKSMGIGVPGVADSEKGIV
IRAVNLFWTKVPLAKEIRKYIDLPIYMGNDANVAALAEAIFGAGKGSKSSITLTLGTGVGSGFILDGKIYNCAHHFALEL
GHIVIGDNGVRCNCGKIGCLETYASATALIREGKKAVEKNPNSLILKLANGDIESITAKNVIDAAKQYDEQAMRIFNDYV
KYLAVGIVNVINMFDPEVIILGGGVANTGDFLIKPLKKEVAENILFKDLPYADIRKAELGNDAGIIGAAILD

Sequences:

>Translated_312_residues
MRIGVDLGGTNIAVGLVDEEGRIVATDSRPTKPERGYEAIAKDIADIAFELIKRSNLSVSDIKSMGIGVPGVADSEKGIV
IRAVNLFWTKVPLAKEIRKYIDLPIYMGNDANVAALAEAIFGAGKGSKSSITLTLGTGVGSGFILDGKIYNCAHHFALEL
GHIVIGDNGVRCNCGKIGCLETYASATALIREGKKAVEKNPNSLILKLANGDIESITAKNVIDAAKQYDEQAMRIFNDYV
KYLAVGIVNVINMFDPEVIILGGGVANTGDFLIKPLKKEVAENILFKDLPYADIRKAELGNDAGIIGAAILD
>Mature_312_residues
MRIGVDLGGTNIAVGLVDEEGRIVATDSRPTKPERGYEAIAKDIADIAFELIKRSNLSVSDIKSMGIGVPGVADSEKGIV
IRAVNLFWTKVPLAKEIRKYIDLPIYMGNDANVAALAEAIFGAGKGSKSSITLTLGTGVGSGFILDGKIYNCAHHFALEL
GHIVIGDNGVRCNCGKIGCLETYASATALIREGKKAVEKNPNSLILKLANGDIESITAKNVIDAAKQYDEQAMRIFNDYV
KYLAVGIVNVINMFDPEVIILGGGVANTGDFLIKPLKKEVAENILFKDLPYADIRKAELGNDAGIIGAAILD

Specific function: Unknown

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=283, Percent_Identity=33.5689045936396, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI298566325, Length=283, Percent_Identity=33.5689045936396, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI4885285, Length=283, Percent_Identity=33.5689045936396, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI190014632, Length=283, Percent_Identity=33.5689045936396, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI298566312, Length=125, Percent_Identity=33.6, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787363, Length=324, Percent_Identity=28.3950617283951, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI87081733, Length=320, Percent_Identity=27.5, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1787878, Length=304, Percent_Identity=24.3421052631579, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786891, Length=306, Percent_Identity=24.1830065359477, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790522, Length=315, Percent_Identity=28.2539682539683, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082127, Length=226, Percent_Identity=22.1238938053097, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082230, Length=265, Percent_Identity=26.0377358490566, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33207; Mature: 33207

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGVDLGGTNIAVGLVDEEGRIVATDSRPTKPERGYEAIAKDIADIAFELIKRSNLSVS
CEEEEEECCCEEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
DIKSMGIGVPGVADSEKGIVIRAVNLFWTKVPLAKEIRKYIDLPIYMGNDANVAALAEAI
HHHHHCCCCCCCCCCCCCEEEEEEEHHHCCCCHHHHHHHHHCCCEEECCCCCHHHHHHHH
FGAGKGSKSSITLTLGTGVGSGFILDGKIYNCAHHFALELGHIVIGDNGVRCNCGKIGCL
HCCCCCCCCEEEEEEECCCCCCEEECCCHHHHHHHHHHHHCEEEECCCCCEECCCCCCHH
ETYASATALIREGKKAVEKNPNSLILKLANGDIESITAKNVIDAAKQYDEQAMRIFNDYV
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYLAVGIVNVINMFDPEVIILGGGVANTGDFLIKPLKKEVAENILFKDLPYADIRKAELG
HHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
NDAGIIGAAILD
CCCCEEEEEECC
>Mature Secondary Structure
MRIGVDLGGTNIAVGLVDEEGRIVATDSRPTKPERGYEAIAKDIADIAFELIKRSNLSVS
CEEEEEECCCEEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
DIKSMGIGVPGVADSEKGIVIRAVNLFWTKVPLAKEIRKYIDLPIYMGNDANVAALAEAI
HHHHHCCCCCCCCCCCCCEEEEEEEHHHCCCCHHHHHHHHHCCCEEECCCCCHHHHHHHH
FGAGKGSKSSITLTLGTGVGSGFILDGKIYNCAHHFALELGHIVIGDNGVRCNCGKIGCL
HCCCCCCCCEEEEEEECCCCCCEEECCCHHHHHHHHHHHHCEEEECCCCCEECCCCCCHH
ETYASATALIREGKKAVEKNPNSLILKLANGDIESITAKNVIDAAKQYDEQAMRIFNDYV
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYLAVGIVNVINMFDPEVIILGGGVANTGDFLIKPLKKEVAENILFKDLPYADIRKAELG
HHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
NDAGIIGAAILD
CCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]