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The map label for this gene is hepT [H]

Identifier: 167039330

GI number: 167039330

Start: 705553

End: 706521

Strand: Direct

Name: hepT [H]

Synonym: Teth514_0672

Alternate gene names: 167039330

Gene position: 705553-706521 (Clockwise)

Preceding gene: 167039329

Following gene: 167039331

Centisome position: 28.71

GC content: 31.68

Gene sequence:

>969_bases
ATGGATAAGTTTTGGAATAATAATTTAGAGATAAAAAATGAGCTTACTGAAGTTATAAAAATAATGGAAAAGCGTATTAA
AAACTCTAACAAATCAATCAGGAATATATTGTTAGATATGATCTATAATAGTGGTAAAATGCTCAGACCTGCTTTTGTAA
TCTTAGCCGGGAAATTTGGAGAATACGATAGAAAGAAAATATTGCCTTTAGCTGCTGCTATAGAAATGCTCCACATGGCA
ACTTTGGTACATGATGATATAATTGATAATGCTTTGATAAGGCGGAGCAAGCCCACTATCCAAGCAGAATATGGAAAAGA
TTATGCTGTATTTATAGGAGATTTCCTTTTTTCTGAGAGTTTTTTGTTGTTATCAGATAATATCGCTATTAGTAATCTAA
AAAAAGTGTCAAAAGTAGTCTCAAAGATATGCAAAGGTGAAATTGGACAATTTGAGAGTCGTCGCAATATCGACATTACA
ATAAATGATTATTTGAGGCGAATAGCTGCGAAAACTGCTGCTCTTTTTGCTCTAAGCTTTTATGTTGGAGCCTATGAAAG
CAAGTGTGACGAAAACTTAGCTAAAGCATTGGGAAGTATAGGCTACAATATTGGCATGGCTTTTCAAATTATAGACGATA
TTTTAGATTATACTGGTCAAGAGGCTGTAGTTGGGAAACCTCTGGGCAATGATATAAGAGAAGGGGTTTTTACTCTGCCT
TTAATCTATTCGCTGGATAAGAATAAAGATAAAATAATGTTAGAATTACTTAAAAAAGAGAGTTATTCTGAGGAAGACAT
AAAACAAATAATTGAATTTGTTCAGCAAAATGGTGGAATAGATCGGTCAAAAATGTTGGCACAAAAATATACTAAAAAGG
CTTTTGATAAAATATCTATGTTGAAAGACTCTCCATCTAAACAAGTTTTAATTGAAGTTACTGGTAAACTTTTATATAGA
AATTATTAA

Upstream 100 bases:

>100_bases
GGAATAGGGACTGGTGTTTTTGTGGGACTGACTGCGAAATTTGTTTTAAAACATTGGGGAAAATTAAAAAATTTAAATTT
ACATTGATTAAGGTGGTTAG

Downstream 100 bases:

>100_bases
TTAAAATAATTAAAAAGAGATGTAAAGTCTTTTTTGGAGGAGATCATTATATGAAAAAATCTATGACTTTTTTTGCAGCT
TTTTTTCTAATATTCACTGT

Product: polyprenyl synthetase

Products: NA

Alternate protein names: HEPPP synthase subunit 2; Spore germination protein C3 [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MDKFWNNNLEIKNELTEVIKIMEKRIKNSNKSIRNILLDMIYNSGKMLRPAFVILAGKFGEYDRKKILPLAAAIEMLHMA
TLVHDDIIDNALIRRSKPTIQAEYGKDYAVFIGDFLFSESFLLLSDNIAISNLKKVSKVVSKICKGEIGQFESRRNIDIT
INDYLRRIAAKTAALFALSFYVGAYESKCDENLAKALGSIGYNIGMAFQIIDDILDYTGQEAVVGKPLGNDIREGVFTLP
LIYSLDKNKDKIMLELLKKESYSEEDIKQIIEFVQQNGGIDRSKMLAQKYTKKAFDKISMLKDSPSKQVLIEVTGKLLYR
NY

Sequences:

>Translated_322_residues
MDKFWNNNLEIKNELTEVIKIMEKRIKNSNKSIRNILLDMIYNSGKMLRPAFVILAGKFGEYDRKKILPLAAAIEMLHMA
TLVHDDIIDNALIRRSKPTIQAEYGKDYAVFIGDFLFSESFLLLSDNIAISNLKKVSKVVSKICKGEIGQFESRRNIDIT
INDYLRRIAAKTAALFALSFYVGAYESKCDENLAKALGSIGYNIGMAFQIIDDILDYTGQEAVVGKPLGNDIREGVFTLP
LIYSLDKNKDKIMLELLKKESYSEEDIKQIIEFVQQNGGIDRSKMLAQKYTKKAFDKISMLKDSPSKQVLIEVTGKLLYR
NY
>Mature_322_residues
MDKFWNNNLEIKNELTEVIKIMEKRIKNSNKSIRNILLDMIYNSGKMLRPAFVILAGKFGEYDRKKILPLAAAIEMLHMA
TLVHDDIIDNALIRRSKPTIQAEYGKDYAVFIGDFLFSESFLLLSDNIAISNLKKVSKVVSKICKGEIGQFESRRNIDIT
INDYLRRIAAKTAALFALSFYVGAYESKCDENLAKALGSIGYNIGMAFQIIDDILDYTGQEAVVGKPLGNDIREGVFTLP
LIYSLDKNKDKIMLELLKKESYSEEDIKQIIEFVQQNGGIDRSKMLAQKYTKKAFDKISMLKDSPSKQVLIEVTGKLLYR
NY

Specific function: Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7) [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=284, Percent_Identity=29.9295774647887, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI4758430, Length=302, Percent_Identity=21.8543046357616, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI83700220, Length=302, Percent_Identity=21.8543046357616, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1789578, Length=311, Percent_Identity=29.5819935691318, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1786623, Length=259, Percent_Identity=26.6409266409266, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17505681, Length=235, Percent_Identity=31.4893617021277, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319475, Length=312, Percent_Identity=28.8461538461538, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24651612, Length=279, Percent_Identity=29.7491039426523, Blast_Score=134, Evalue=7e-32,
Organism=Drosophila melanogaster, GI281365769, Length=267, Percent_Identity=23.5955056179775, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24660002, Length=267, Percent_Identity=23.5955056179775, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014119
- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.30 [H]

Molecular weight: Translated: 36628; Mature: 36628

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKFWNNNLEIKNELTEVIKIMEKRIKNSNKSIRNILLDMIYNSGKMLRPAFVILAGKFG
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHEEEECCCC
EYDRKKILPLAAAIEMLHMATLVHDDIIDNALIRRSKPTIQAEYGKDYAVFIGDFLFSES
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHCCC
FLLLSDNIAISNLKKVSKVVSKICKGEIGQFESRRNIDITINDYLRRIAAKTAALFALSF
EEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHH
YVGAYESKCDENLAKALGSIGYNIGMAFQIIDDILDYTGQEAVVGKPLGNDIREGVFTLP
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHH
LIYSLDKNKDKIMLELLKKESYSEEDIKQIIEFVQQNGGIDRSKMLAQKYTKKAFDKISM
HHEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LKDSPSKQVLIEVTGKLLYRNY
HHCCCCCEEHHHHHHHHHHCCC
>Mature Secondary Structure
MDKFWNNNLEIKNELTEVIKIMEKRIKNSNKSIRNILLDMIYNSGKMLRPAFVILAGKFG
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHEEEECCCC
EYDRKKILPLAAAIEMLHMATLVHDDIIDNALIRRSKPTIQAEYGKDYAVFIGDFLFSES
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHCCC
FLLLSDNIAISNLKKVSKVVSKICKGEIGQFESRRNIDITINDYLRRIAAKTAALFALSF
EEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHH
YVGAYESKCDENLAKALGSIGYNIGMAFQIIDDILDYTGQEAVVGKPLGNDIREGVFTLP
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHH
LIYSLDKNKDKIMLELLKKESYSEEDIKQIIEFVQQNGGIDRSKMLAQKYTKKAFDKISM
HHEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LKDSPSKQVLIEVTGKLLYRNY
HHCCCCCEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 2121900; 9720033 [H]