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The map label for this gene is apbE [H]

Identifier: 167039331

GI number: 167039331

Start: 706572

End: 707609

Strand: Direct

Name: apbE [H]

Synonym: Teth514_0673

Alternate gene names: 167039331

Gene position: 706572-707609 (Clockwise)

Preceding gene: 167039330

Following gene: 167039332

Centisome position: 28.75

GC content: 31.7

Gene sequence:

>1038_bases
ATGAAAAAATCTATGACTTTTTTTGCAGCTTTTTTTCTAATATTCACTGTTGCCAGTATATTTTCTGGGTGTTCAAATAA
AAATTCACAGCCTATATCTGATACACAATTTGCTTTAGATACTTATTGTACAATAAGCATATACGATAATGTGCCGAAAA
AGGTTTTAGATGAGGGATTTAAAGCTATAAAAGATGTAGAAGACAAGATGAGTGTTACCATCAAAAACAGTGAAGTGAAT
CAAATTAATGAGAATGCAGGTATTAGACCTGTTAAGGTTTCACCTGACACCTTTTATGTGATAAAAAAAGCGGTACATTT
TTCTGATGTTGAAAAGGGGTATTTTGATATTACAGTAGGACCTATAGTAAAACTTTGGAATATAGGAACTGATAAAGCTA
AAGTACCTTCCCCTGAAGAAATAAAAGCTAAACTCCCTCTTGTAAATTATAAGGATATAATATTGGACGAAAAGAATATG
ACTATTATGCTGAAAAATAAAGGTATGAGTATAGATTTAGGAGGTATTGCAAAAGGATATGCGGCAGATAAAGTAGCACA
AGTTTTAAAGAAAGAGGGTGTAAAACATGCCATAATTAATTTAGGAGGTGATGTTCTTACAATAGGAACAAAACCTGATG
GTGGTAACTGGCGTATAGGTATTCAAACTCCTTTTAAACCAAGAGGTGAATATTTGGGCATAGTAGAGGTTTCCAATAAA
GCTGTTGTTACTTCTGGAGTTTATGAAAGGTATTTTGAAAAAGATGGAAAATTATATCATCACATACTAAATCCTTTTAC
AGGTTATCCTGTAGATAATCACTTATACAGTGTGACAATAATAACTGATACTTCTATAGATGGTGATGCTCTTTCAAAAA
TTTTTGTAATTGGCTTAGAAGAAGGTTTGAAGTTGGCAGAAAGTTTACCTGGAGTGCAAGCTATATTTGTTACAGACGAT
AAAAAAGTATATATAACCTCTGGTCTAAAAGGCAACTTTAAAGTTACTGATCCTGAATATACTTTAATGACTAAATAA

Upstream 100 bases:

>100_bases
AACAAGTTTTAATTGAAGTTACTGGTAAACTTTTATATAGAAATTATTAATTAAAATAATTAAAAAGAGATGTAAAGTCT
TTTTTGGAGGAGATCATTAT

Downstream 100 bases:

>100_bases
TTTCTTGCAGGAGGAAACATTATGAACAAATCAGAATTTTCGAGAGTTTGGAAGGGATTTTGGCAATTAGCAGATCCTAA
AATATGGATAGCCTCTACAG

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKKSMTFFAAFFLIFTVASIFSGCSNKNSQPISDTQFALDTYCTISIYDNVPKKVLDEGFKAIKDVEDKMSVTIKNSEVN
QINENAGIRPVKVSPDTFYVIKKAVHFSDVEKGYFDITVGPIVKLWNIGTDKAKVPSPEEIKAKLPLVNYKDIILDEKNM
TIMLKNKGMSIDLGGIAKGYAADKVAQVLKKEGVKHAIINLGGDVLTIGTKPDGGNWRIGIQTPFKPRGEYLGIVEVSNK
AVVTSGVYERYFEKDGKLYHHILNPFTGYPVDNHLYSVTIITDTSIDGDALSKIFVIGLEEGLKLAESLPGVQAIFVTDD
KKVYITSGLKGNFKVTDPEYTLMTK

Sequences:

>Translated_345_residues
MKKSMTFFAAFFLIFTVASIFSGCSNKNSQPISDTQFALDTYCTISIYDNVPKKVLDEGFKAIKDVEDKMSVTIKNSEVN
QINENAGIRPVKVSPDTFYVIKKAVHFSDVEKGYFDITVGPIVKLWNIGTDKAKVPSPEEIKAKLPLVNYKDIILDEKNM
TIMLKNKGMSIDLGGIAKGYAADKVAQVLKKEGVKHAIINLGGDVLTIGTKPDGGNWRIGIQTPFKPRGEYLGIVEVSNK
AVVTSGVYERYFEKDGKLYHHILNPFTGYPVDNHLYSVTIITDTSIDGDALSKIFVIGLEEGLKLAESLPGVQAIFVTDD
KKVYITSGLKGNFKVTDPEYTLMTK
>Mature_345_residues
MKKSMTFFAAFFLIFTVASIFSGCSNKNSQPISDTQFALDTYCTISIYDNVPKKVLDEGFKAIKDVEDKMSVTIKNSEVN
QINENAGIRPVKVSPDTFYVIKKAVHFSDVEKGYFDITVGPIVKLWNIGTDKAKVPSPEEIKAKLPLVNYKDIILDEKNM
TIMLKNKGMSIDLGGIAKGYAADKVAQVLKKEGVKHAIINLGGDVLTIGTKPDGGNWRIGIQTPFKPRGEYLGIVEVSNK
AVVTSGVYERYFEKDGKLYHHILNPFTGYPVDNHLYSVTIITDTSIDGDALSKIFVIGLEEGLKLAESLPGVQAIFVTDD
KKVYITSGLKGNFKVTDPEYTLMTK

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=307, Percent_Identity=28.3387622149837, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 38087; Mature: 38087

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSMTFFAAFFLIFTVASIFSGCSNKNSQPISDTQFALDTYCTISIYDNVPKKVLDEGF
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEEEECCCCHHHHHHHH
KAIKDVEDKMSVTIKNSEVNQINENAGIRPVKVSPDTFYVIKKAVHFSDVEKGYFDITVG
HHHHCCCCCEEEEEECCCCHHHHCCCCEEEEEECCCEEEEEHHHHHHHCCCCCEEEEEHH
PIVKLWNIGTDKAKVPSPEEIKAKLPLVNYKDIILDEKNMTIMLKNKGMSIDLGGIAKGY
HEEEEECCCCCCCCCCCCHHHHEECCCCCCHHEEEECCCCEEEEECCCCEEECCCCCCCH
AADKVAQVLKKEGVKHAIINLGGDVLTIGTKPDGGNWRIGIQTPFKPRGEYLGIVEVSNK
HHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCEEEEEECCCCCCCCEEEEEEECCC
AVVTSGVYERYFEKDGKLYHHILNPFTGYPVDNHLYSVTIITDTSIDGDALSKIFVIGLE
EEEEHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCHHHHCEEEEEEHH
EGLKLAESLPGVQAIFVTDDKKVYITSGLKGNFKVTDPEYTLMTK
HHHHHHHHCCCCEEEEEECCCEEEEECCCCCCEEEECCCEEEEEC
>Mature Secondary Structure
MKKSMTFFAAFFLIFTVASIFSGCSNKNSQPISDTQFALDTYCTISIYDNVPKKVLDEGF
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEEEECCCCHHHHHHHH
KAIKDVEDKMSVTIKNSEVNQINENAGIRPVKVSPDTFYVIKKAVHFSDVEKGYFDITVG
HHHHCCCCCEEEEEECCCCHHHHCCCCEEEEEECCCEEEEEHHHHHHHCCCCCEEEEEHH
PIVKLWNIGTDKAKVPSPEEIKAKLPLVNYKDIILDEKNMTIMLKNKGMSIDLGGIAKGY
HEEEEECCCCCCCCCCCCHHHHEECCCCCCHHEEEECCCCEEEEECCCCEEECCCCCCCH
AADKVAQVLKKEGVKHAIINLGGDVLTIGTKPDGGNWRIGIQTPFKPRGEYLGIVEVSNK
HHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCEEEEEECCCCCCCCEEEEEEECCC
AVVTSGVYERYFEKDGKLYHHILNPFTGYPVDNHLYSVTIITDTSIDGDALSKIFVIGLE
EEEEHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCHHHHCEEEEEEHH
EGLKLAESLPGVQAIFVTDDKKVYITSGLKGNFKVTDPEYTLMTK
HHHHHHHHCCCCEEEEEECCCEEEEECCCCCCEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]