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The map label for this gene is yggV [C]

Identifier: 167039211

GI number: 167039211

Start: 573262

End: 573858

Strand: Direct

Name: yggV [C]

Synonym: Teth514_0552

Alternate gene names: 167039211

Gene position: 573262-573858 (Clockwise)

Preceding gene: 167039210

Following gene: 167039212

Centisome position: 23.33

GC content: 31.32

Gene sequence:

>597_bases
TTGAAAATAATAATAGCAACCCACAATCCTCACAAAACTGAAGAAATAAAAAATTTTTTTAAAGGCTATCCTGTTGAAAT
TTATTCTATGGCAGACTTGGGTATAAAAGAAGACATAGAAGAGACAGGAGATACGATTGAAGAAAATGCTCTTATCAAGG
CTCGTTTTTTAAAAGAAAAAGTTGATGGAATTGTTATAGCTGACGATACAGGATTGTTTGTGGAGCATTTAAATGGACAA
CCTGGAGTATATTCAGCAAGATTTGCTGGTGAAAATGCTACCTATGAAGATAACAACAAAAAATTATTAAAACTATTAGA
GGGTGTTCCTTACGAAAAAAGAAAAGCTTATTTTAAGACAGTAATAGCAGTGGTAGAAAGGGAAAAAGAAACTTTATTAG
AAGGTAAATTAGAAGGGCACATTTTAGATCATCCTCGAGGGAAAAATGGTTTTGGATATGACCCAGTTTTTTATGTCGAT
AATTTAGGAAAGAGTTTGGCAGAACTTACTATGGAAGAAAAAAATAAGATAAGTCATAGAGCTGATGCTCTTATGAAGTT
AAAAAATTATATTTTAAAACGTCTGGAGGAAAAATAA

Upstream 100 bases:

>100_bases
ACAGACCTTTTAAGCCTTGCAGAATATGGGATTGAACAGATTATCAAAATTCAAAAAGAAGTTCTTTCAGATATTGTAGA
TAAAATAGGAGTTGATTCAG

Downstream 100 bases:

>100_bases
ATGGTTTTAGCAGTTATTAGCGACACACATGGTATATTTGCGCTGGTTAGAAAAAAATTGCGGGAGCTTAAAGGAATAGA
TTATCTTATTCATTTAGGAG

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MKIIIATHNPHKTEEIKNFFKGYPVEIYSMADLGIKEDIEETGDTIEENALIKARFLKEKVDGIVIADDTGLFVEHLNGQ
PGVYSARFAGENATYEDNNKKLLKLLEGVPYEKRKAYFKTVIAVVEREKETLLEGKLEGHILDHPRGKNGFGYDPVFYVD
NLGKSLAELTMEEKNKISHRADALMKLKNYILKRLEEK

Sequences:

>Translated_198_residues
MKIIIATHNPHKTEEIKNFFKGYPVEIYSMADLGIKEDIEETGDTIEENALIKARFLKEKVDGIVIADDTGLFVEHLNGQ
PGVYSARFAGENATYEDNNKKLLKLLEGVPYEKRKAYFKTVIAVVEREKETLLEGKLEGHILDHPRGKNGFGYDPVFYVD
NLGKSLAELTMEEKNKISHRADALMKLKNYILKRLEEK
>Mature_198_residues
MKIIIATHNPHKTEEIKNFFKGYPVEIYSMADLGIKEDIEETGDTIEENALIKARFLKEKVDGIVIADDTGLFVEHLNGQ
PGVYSARFAGENATYEDNNKKLLKLLEGVPYEKRKAYFKTVIAVVEREKETLLEGKLEGHILDHPRGKNGFGYDPVFYVD
NLGKSLAELTMEEKNKISHRADALMKLKNYILKRLEEK

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=194, Percent_Identity=29.8969072164948, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI31657144, Length=159, Percent_Identity=31.4465408805031, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1789324, Length=186, Percent_Identity=42.4731182795699, Blast_Score=148, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17556833, Length=192, Percent_Identity=33.8541666666667, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322529, Length=163, Percent_Identity=31.9018404907975, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI19920712, Length=195, Percent_Identity=32.8205128205128, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22601; Mature: 22601

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIIATHNPHKTEEIKNFFKGYPVEIYSMADLGIKEDIEETGDTIEENALIKARFLKEK
CEEEEECCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHH
VDGIVIADDTGLFVEHLNGQPGVYSARFAGENATYEDNNKKLLKLLEGVPYEKRKAYFKT
HCEEEEECCCCEEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHH
VIAVVEREKETLLEGKLEGHILDHPRGKNGFGYDPVFYVDNLGKSLAELTMEEKNKISHR
HHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ADALMKLKNYILKRLEEK
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIIIATHNPHKTEEIKNFFKGYPVEIYSMADLGIKEDIEETGDTIEENALIKARFLKEK
CEEEEECCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHH
VDGIVIADDTGLFVEHLNGQPGVYSARFAGENATYEDNNKKLLKLLEGVPYEKRKAYFKT
HCEEEEECCCCEEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHH
VIAVVEREKETLLEGKLEGHILDHPRGKNGFGYDPVFYVDNLGKSLAELTMEEKNKISHR
HHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ADALMKLKNYILKRLEEK
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA