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The map label for this gene is yabD [H]

Identifier: 167038740

GI number: 167038740

Start: 69756

End: 70523

Strand: Direct

Name: yabD [H]

Synonym: Teth514_0067

Alternate gene names: 167038740

Gene position: 69756-70523 (Clockwise)

Preceding gene: 167038739

Following gene: 167038741

Centisome position: 2.84

GC content: 33.85

Gene sequence:

>768_bases
TTGTTGGTGGATTCTCACGCTCATCTTGAAGATGAGAAATACGATAAAGATAGAGAAGAAGTTATTGAAGAATGCAAAAA
AGATCTCACATTTTTAATAAATGTGGGGTCTAATATCTTAACTTCTAAACAGTCTATTAAGCTAGCTCACAACTATGACT
TTATATACGCTTCTGTTGGAATTCATCCTCATGATGCACAAAAGGAATTTGACAAAGTGGAAGAAATAGAGAGGTTGGCT
TTGCAGGAAAAGGTTGTAGCAATAGGAGAAATAGGTTTAGATTATTATTACAATGACCCTCCTAAAGAGTTTCAAAAAGA
GGTCTTCATAAAGCAAATAAGGCTTGCAAAAAAGCTTAATCTTCCAATAATAATACACGATAGGGATGCTCATGGAGATA
TACTAGATATATTAAAACAAGAATGGACGAAAGATTTAAGAGGGGTTTTTCATAGTTATTCAGGAAGTGTTGAAATGGCT
TTTCAAGCAATTGAAATGAACTTTTACATTTCTTTAGGGGGACCTGTGACATTTAAAAATGCAAAAAAGCCAAAAGAAGT
AGTAAAAGCTGTTCCCATCGAAAAACTTTTAATTGAAACAGATAGCCCTTATCTTACTCCTGAGCCTTATAGAGGGAAAA
GGAATACACCGGTGTATGTGAAATTTGTAGCAGAAAAAATTGCAGAATTAAGAGAGATGTCTTATGAGGAGGTTTGTAGG
ATTACTGCTGAAAATGCCATAAAACTTTTTGACATCCTTCCCAAATAA

Upstream 100 bases:

>100_bases
AGGAATGCTTTTGGCAGCATCTACCGAAGGAAAAATGTCTCTTCTTACGGTAGACAGGGATATAGAAAGTGGGGCAAAGA
TAAGCTAAGGAGTGATAAAA

Downstream 100 bases:

>100_bases
AAATATTAAAAAACAACTTCCTGTTTTTAGGGGAGGTATCAAAAGTCAAAAAAATGCGTATAATATCATTAAGTTTAATT
TCACCATAAATGAAAAATTG

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MLVDSHAHLEDEKYDKDREEVIEECKKDLTFLINVGSNILTSKQSIKLAHNYDFIYASVGIHPHDAQKEFDKVEEIERLA
LQEKVVAIGEIGLDYYYNDPPKEFQKEVFIKQIRLAKKLNLPIIIHDRDAHGDILDILKQEWTKDLRGVFHSYSGSVEMA
FQAIEMNFYISLGGPVTFKNAKKPKEVVKAVPIEKLLIETDSPYLTPEPYRGKRNTPVYVKFVAEKIAELREMSYEEVCR
ITAENAIKLFDILPK

Sequences:

>Translated_255_residues
MLVDSHAHLEDEKYDKDREEVIEECKKDLTFLINVGSNILTSKQSIKLAHNYDFIYASVGIHPHDAQKEFDKVEEIERLA
LQEKVVAIGEIGLDYYYNDPPKEFQKEVFIKQIRLAKKLNLPIIIHDRDAHGDILDILKQEWTKDLRGVFHSYSGSVEMA
FQAIEMNFYISLGGPVTFKNAKKPKEVVKAVPIEKLLIETDSPYLTPEPYRGKRNTPVYVKFVAEKIAELREMSYEEVCR
ITAENAIKLFDILPK
>Mature_255_residues
MLVDSHAHLEDEKYDKDREEVIEECKKDLTFLINVGSNILTSKQSIKLAHNYDFIYASVGIHPHDAQKEFDKVEEIERLA
LQEKVVAIGEIGLDYYYNDPPKEFQKEVFIKQIRLAKKLNLPIIIHDRDAHGDILDILKQEWTKDLRGVFHSYSGSVEMA
FQAIEMNFYISLGGPVTFKNAKKPKEVVKAVPIEKLLIETDSPYLTPEPYRGKRNTPVYVKFVAEKIAELREMSYEEVCR
ITAENAIKLFDILPK

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=264, Percent_Identity=30.3030303030303, Blast_Score=127, Evalue=8e-30,
Organism=Homo sapiens, GI110349734, Length=264, Percent_Identity=30.3030303030303, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI226061853, Length=270, Percent_Identity=30, Blast_Score=124, Evalue=8e-29,
Organism=Homo sapiens, GI226061614, Length=255, Percent_Identity=29.0196078431373, Blast_Score=121, Evalue=7e-28,
Organism=Homo sapiens, GI225903439, Length=247, Percent_Identity=31.9838056680162, Blast_Score=114, Evalue=7e-26,
Organism=Homo sapiens, GI14042943, Length=251, Percent_Identity=32.2709163346614, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI226061595, Length=228, Percent_Identity=28.0701754385965, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI225903424, Length=159, Percent_Identity=32.7044025157233, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1787342, Length=256, Percent_Identity=40.625, Blast_Score=201, Evalue=3e-53,
Organism=Escherichia coli, GI48994985, Length=261, Percent_Identity=34.8659003831418, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI87082439, Length=262, Percent_Identity=31.2977099236641, Blast_Score=140, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17559024, Length=283, Percent_Identity=33.5689045936396, Blast_Score=140, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI71980746, Length=261, Percent_Identity=26.0536398467433, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17543026, Length=218, Percent_Identity=30.2752293577982, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17565396, Length=219, Percent_Identity=32.8767123287671, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24648690, Length=284, Percent_Identity=29.9295774647887, Blast_Score=130, Evalue=6e-31,
Organism=Drosophila melanogaster, GI221330018, Length=279, Percent_Identity=26.8817204301075, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24586117, Length=279, Percent_Identity=26.8817204301075, Blast_Score=81, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29472; Mature: 29472

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVDSHAHLEDEKYDKDREEVIEECKKDLTFLINVGSNILTSKQSIKLAHNYDFIYASVG
CCCCCCCCCCCHHCCCCHHHHHHHHHHHHEEEEECCCHHHCCHHHEEEEECCEEEEEEEC
IHPHDAQKEFDKVEEIERLALQEKVVAIGEIGLDYYYNDPPKEFQKEVFIKQIRLAKKLN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
LPIIIHDRDAHGDILDILKQEWTKDLRGVFHSYSGSVEMAFQAIEMNFYISLGGPVTFKN
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEEEEEEEEECCEEEECC
AKKPKEVVKAVPIEKLLIETDSPYLTPEPYRGKRNTPVYVKFVAEKIAELREMSYEEVCR
CCCHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCHHHHHH
ITAENAIKLFDILPK
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MLVDSHAHLEDEKYDKDREEVIEECKKDLTFLINVGSNILTSKQSIKLAHNYDFIYASVG
CCCCCCCCCCCHHCCCCHHHHHHHHHHHHEEEEECCCHHHCCHHHEEEEECCEEEEEEEC
IHPHDAQKEFDKVEEIERLALQEKVVAIGEIGLDYYYNDPPKEFQKEVFIKQIRLAKKLN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
LPIIIHDRDAHGDILDILKQEWTKDLRGVFHSYSGSVEMAFQAIEMNFYISLGGPVTFKN
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEEEEEEEEECCEEEECC
AKKPKEVVKAVPIEKLLIETDSPYLTPEPYRGKRNTPVYVKFVAEKIAELREMSYEEVCR
CCCHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCHHHHHH
ITAENAIKLFDILPK
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]