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The map label for this gene is cmk

Identifier: 16273655

GI number: 16273655

Start: 1711447

End: 1712115

Strand: Reverse

Name: cmk

Synonym: HI1646m

Alternate gene names: 16273655

Gene position: 1712115-1711447 (Counterclockwise)

Preceding gene: 16273537

Following gene: 16273533

Centisome position: 93.55

GC content: 38.71

Gene sequence:

>669_bases
ATGATTATTACTGTTGATGGTCCTAGTGGTGCTGGGAAAGGGACGCTTTGTTATGCGTTGGCTGAAAAGTTGGGCTATGC
ATTGTTGGATAGTGGGGCGATTTATCGCGTTACTGCATTGGCAGCGTTGCAACGTAAAACTGATCTAACAAATGAAACAG
ATTTAGCAGAATTAGCACGTCATTTAGATATTCAATTTATTCCTCAAAATGGCGAGGTAAACATTTTTCTTGCAGGAATG
GATGTGAGCCGTTTAATTCGCACGCAAGAAGTGGCAGATGCTGCGTCAAAAGTAGCAGTCTTTCAAAAAGTGCGGTCAGC
TTTATTACAACTTCAGCAAGATTTTGCGAAAAATGATGGATTAATTGCGGATGGCAGAGATATGGGGACTGTGGTATTCC
CAAATGCACAAGTAAAATTATTTTTAGATGCAAGTGCTGAAGAACGTGCAAAAAGACGCTATAAACAGTTGCAAAATAAA
GGAATAAATGGTAACTTTGCACAGATTTTAGCCGAGATAAAAGAGCGTGATTTTCGTGATAGAAATCGTGAAGTTGCGCC
GCTAAAACCAGCAGATGATGCTTTTTATTATTCTTTAAATTCTTCCATCATTTCTTGTGCTTTTTTTACCATATCTTCTG
AACCAACAAATAGTGGAACACGTTCATGA

Upstream 100 bases:

>100_bases
CAAAACATGGAAGCTAGTAATAATCTCTAGGATGGTAATGAGGGGCAATTGTCTCTATAATGCGCAAAATTTTGAGAATG
AAAGGATAATTTGTATGGGA

Downstream 100 bases:

>100_bases
AGTGCGGTTGGTTCGATATCTAAAATTCGACGATAACCATCTGTTGCGACACCACCAGCTTGCTCCGCTAAAAATGCAAT
AGGATTGCCTTCATATAATA

Product: cytidylate kinase

Products: NA

Alternate protein names: CK 2; Cytidine monophosphate kinase 2; CMP kinase 2

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MIITVDGPSGAGKGTLCYALAEKLGYALLDSGAIYRVTALAALQRKTDLTNETDLAELARHLDIQFIPQNGEVNIFLAGM
DVSRLIRTQEVADAASKVAVFQKVRSALLQLQQDFAKNDGLIADGRDMGTVVFPNAQVKLFLDASAEERAKRRYKQLQNK
GINGNFAQILAEIKERDFRDRNREVAPLKPADDAFYYSLNSSIISCAFFTISSEPTNSGTRS

Sequences:

>Translated_222_residues
MIITVDGPSGAGKGTLCYALAEKLGYALLDSGAIYRVTALAALQRKTDLTNETDLAELARHLDIQFIPQNGEVNIFLAGM
DVSRLIRTQEVADAASKVAVFQKVRSALLQLQQDFAKNDGLIADGRDMGTVVFPNAQVKLFLDASAEERAKRRYKQLQNK
GINGNFAQILAEIKERDFRDRNREVAPLKPADDAFYYSLNSSIISCAFFTISSEPTNSGTRS
>Mature_222_residues
MIITVDGPSGAGKGTLCYALAEKLGYALLDSGAIYRVTALAALQRKTDLTNETDLAELARHLDIQFIPQNGEVNIFLAGM
DVSRLIRTQEVADAASKVAVFQKVRSALLQLQQDFAKNDGLIADGRDMGTVVFPNAQVKLFLDASAEERAKRRYKQLQNK
GINGNFAQILAEIKERDFRDRNREVAPLKPADDAFYYSLNSSIISCAFFTISSEPTNSGTRS

Specific function: ATP, Datp, And GTP Are Equally Effective As Phosphate Donors. CMP And Dcmp Are The Best Phosphate Acceptors. [C]

COG id: COG0283

COG function: function code F; Cytidylate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylate kinase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1787139, Length=204, Percent_Identity=63.2352941176471, Blast_Score=252, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KCY2_HAEIN (P43893)

Other databases:

- EMBL:   L42023
- PIR:   H64134
- RefSeq:   NP_439788.1
- ProteinModelPortal:   P43893
- SMR:   P43893
- GeneID:   950485
- GenomeReviews:   L42023_GR
- NMPDR:   fig|71421.1.peg.1560
- TIGR:   HI_1646
- HOGENOM:   HBG354377
- OMA:   GIRNIVN
- ProtClustDB:   PRK00023
- BioCyc:   HINF71421:HI_1646-MONOMER
- BRENDA:   2.7.4.14
- GO:   GO:0005737
- HAMAP:   MF_00238
- InterPro:   IPR003136
- InterPro:   IPR011994
- PANTHER:   PTHR21299:SF2
- TIGRFAMs:   TIGR00017

Pfam domain/function: PF02224 Cytidylate_kin

EC number: =2.7.4.14

Molecular weight: Translated: 24368; Mature: 24368

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIITVDGPSGAGKGTLCYALAEKLGYALLDSGAIYRVTALAALQRKTDLTNETDLAELAR
CEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHH
HLDIQFIPQNGEVNIFLAGMDVSRLIRTQEVADAASKVAVFQKVRSALLQLQQDFAKNDG
HCCEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LIADGRDMGTVVFPNAQVKLFLDASAEERAKRRYKQLQNKGINGNFAQILAEIKERDFRD
EEECCCCCCEEEECCCEEEEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
RNREVAPLKPADDAFYYSLNSSIISCAFFTISSEPTNSGTRS
CCCCCCCCCCCCCCEEEEECCCEEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MIITVDGPSGAGKGTLCYALAEKLGYALLDSGAIYRVTALAALQRKTDLTNETDLAELAR
CEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHH
HLDIQFIPQNGEVNIFLAGMDVSRLIRTQEVADAASKVAVFQKVRSALLQLQQDFAKNDG
HCCEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LIADGRDMGTVVFPNAQVKLFLDASAEERAKRRYKQLQNKGINGNFAQILAEIKERDFRD
EEECCCCCCEEEECCCEEEEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
RNREVAPLKPADDAFYYSLNSSIISCAFFTISSEPTNSGTRS
CCCCCCCCCCCCCCEEEEECCCEEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800