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The map label for this gene is pdxS

Identifier: 16273535

GI number: 16273535

Start: 1712590

End: 1713465

Strand: Direct

Name: pdxS

Synonym: HI1647

Alternate gene names: 16273535

Gene position: 1712590-1713465 (Clockwise)

Preceding gene: 16273534

Following gene: 30995464

Centisome position: 93.58

GC content: 43.72

Gene sequence:

>876_bases
ATGGCTGAAAATCGTTATGAACTAAATAAAAACTTAGCACAGATGCTCAAAGGTGGTGTTATCATGGATGTTCAAAACCC
TGAACAAGCTCGCATTGCAGAAGCTGCTGGTGCAGCTGCAGTGATGGCTTTGGAACGAATTCCTGCAGATATTCGTGCTG
TTGGAGGTGTCTCTCGAATGAGCGATCCTAAGATGATCAAGGAAATCCAAGGAGCAGTTAGCATTCCAGTTATGGCAAAA
GTTAGAATTGGACATTTCGTTGAGGCTCAGATTTTGGAAGCTATTGAAATTGACTATATCGATGAGAGTGAAGTGCTTTC
TCCAGCTGACAACCGTTTCCATGTGGACAAGAAAGAATTCCAAGTACCTTTTGTATGTGGTGCCAAGGATTTGGGCGAGG
CCTTGCGTCGTATCGCTGAAGGGGCTTCAATGATTCGTACAAAAGGAGAACCAGGAACAGGAGATATCGTCCAAGCTGTT
CGCCATATGCGCATGATGAGTCAAGAAATTCGTCGCATTCAAAATTTACGTGAGGACGAGCTCTATGTTGCGGCCAAAGA
TTTACAAGTTCCTGTAGAATTGGTTCAATACGTCCATAAGCATGGGAAATTGCCAGTTGTCAACTTCGCAGCTGGAGGAA
TTGCAACTCCAGCAGATGCGGCCTTGATGATGCAACTTGGCGCAGAGGGTGTCTTTGTTGGTTCAGGTATTTTTAAGTCA
GGAGATCCTATAAAACGTGCGAGCGCTATTGTCAAAGCTGTAACTAACTATCGAAATCCACAAATCCTAGCACAAATCTC
CGAAGATTTAGGTGAAGCCATGGTTGGTATCAATGAAAATGAAATCCAAATTCTCATGGCTGAGCGAGGAAAATAA

Upstream 100 bases:

>100_bases
AATATATACACATTTTTTCAAACTTGTTCTAAAGACTTTTCTACATTACAATAAAAAACGTAGCTATCAATACAAATAAT
CAAATAATGAGGACAAAGAA

Downstream 100 bases:

>100_bases
ATGAAAATCGGAATATTAGCTCTACAAGGTGCCTTTGCGGAACATGCACGAATGCTAGAAAAATTAGGAATTGAAAGTGT
CGAACTGAGAAATTTAAAAA

Product: pyridoxal biosynthesis lyase PdxS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MAENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMALERIPADIRAVGGVSRMSDPKMIKEIQGAVSIPVMAK
VRIGHFVEAQILEAIEIDYIDESEVLSPADNRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
RHMRMMSQEIRRIQNLREDELYVAAKDLQVPVELVQYVHKHGKLPVVNFAAGGIATPADAALMMQLGAEGVFVGSGIFKS
GDPIKRASAIVKAVTNYRNPQILAQISEDLGEAMVGINENEIQILMAERGK

Sequences:

>Translated_291_residues
MAENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMALERIPADIRAVGGVSRMSDPKMIKEIQGAVSIPVMAK
VRIGHFVEAQILEAIEIDYIDESEVLSPADNRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
RHMRMMSQEIRRIQNLREDELYVAAKDLQVPVELVQYVHKHGKLPVVNFAAGGIATPADAALMMQLGAEGVFVGSGIFKS
GDPIKRASAIVKAVTNYRNPQILAQISEDLGEAMVGINENEIQILMAERGK
>Mature_290_residues
AENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMALERIPADIRAVGGVSRMSDPKMIKEIQGAVSIPVMAKV
RIGHFVEAQILEAIEIDYIDESEVLSPADNRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAVR
HMRMMSQEIRRIQNLREDELYVAAKDLQVPVELVQYVHKHGKLPVVNFAAGGIATPADAALMMQLGAEGVFVGSGIFKSG
DPIKRASAIVKAVTNYRNPQILAQISEDLGEAMVGINENEIQILMAERGK

Specific function: Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring

COG id: COG0214

COG function: function code H; Pyridoxine biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxS/SNZ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323743, Length=279, Percent_Identity=64.8745519713262, Blast_Score=380, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6323996, Length=277, Percent_Identity=67.5090252707581, Blast_Score=372, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6321049, Length=277, Percent_Identity=67.1480144404332, Blast_Score=371, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXS_HAEI8 (Q4QJU5)

Other databases:

- EMBL:   CP000057
- RefSeq:   YP_249362.1
- ProteinModelPortal:   Q4QJU5
- SMR:   Q4QJU5
- STRING:   Q4QJU5
- GeneID:   3431202
- GenomeReviews:   CP000057_GR
- KEGG:   hit:NTHI1950
- eggNOG:   COG0214
- HOGENOM:   HBG292342
- OMA:   ARMSDPD
- PhylomeDB:   Q4QJU5
- ProtClustDB:   PRK04180
- BioCyc:   HINF281310:NTHI1950-MONOMER
- HAMAP:   MF_01824
- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR001852
- Gene3D:   G3DSA:3.20.20.70
- PIRSF:   PIRSF029271
- TIGRFAMs:   TIGR00343

Pfam domain/function: PF01680 SOR_SNZ; SSF51366 RibP_bind_barrel

EC number: NA

Molecular weight: Translated: 31682; Mature: 31551

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS01235 PDXS_SNZ_1; PS51129 PDXS_SNZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMALERIPADIRAVGGVSRM
CCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHC
SDPKMIKEIQGAVSIPVMAKVRIGHFVEAQILEAIEIDYIDESEVLSPADNRFHVDKKEF
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCEECCHHHC
QVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAVRHMRMMSQEIRRIQNLREDE
CCCEEECCHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
LYVAAKDLQVPVELVQYVHKHGKLPVVNFAAGGIATPADAALMMQLGAEGVFVGSGIFKS
EEEEECCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHCCCEEEECCCCCCC
GDPIKRASAIVKAVTNYRNPQILAQISEDLGEAMVGINENEIQILMAERGK
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
>Mature Secondary Structure 
AENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMALERIPADIRAVGGVSRM
CCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHC
SDPKMIKEIQGAVSIPVMAKVRIGHFVEAQILEAIEIDYIDESEVLSPADNRFHVDKKEF
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCEECCHHHC
QVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAVRHMRMMSQEIRRIQNLREDE
CCCEEECCHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
LYVAAKDLQVPVELVQYVHKHGKLPVVNFAAGGIATPADAALMMQLGAEGVFVGSGIFKS
EEEEECCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHCCCEEEECCCCCCC
GDPIKRASAIVKAVTNYRNPQILAQISEDLGEAMVGINENEIQILMAERGK
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA