Click here to switch to the map view.

The map label for this gene is fbp [H]

Identifier: 16273534

GI number: 16273534

Start: 1710527

End: 1711528

Strand: Direct

Name: fbp [H]

Synonym: HI1645

Alternate gene names: 16273534

Gene position: 1710527-1711528 (Clockwise)

Preceding gene: 16273532

Following gene: 16273535

Centisome position: 93.46

GC content: 37.13

Gene sequence:

>1002_bases
ATGAAAACATTGAGTGAATTTATCGTTGAACGCCAAGCTGAATATCCAAACGCAAAGGGGGAATTGAGTGGTATTTTGTC
GTCAATTCGTCTTTTAGCGAAAATAATTCATCGAGATATTAACAAAGCAGGTTTAACAAATATTCTCGGTCAATCTGGTA
TTGAAAATGTACAAGGCGAAAGTCAAATGAAACTCGATTTATTCGCCCATAACACGATGAAAGCGGCATTAATGGCACGT
GAAGAAGTGGCTGGTTTTGCCTCTGAAGAAGAAGAAAGTTTTATCGCATTTGATACAGAACGTGGCCGTAATGCAAAATA
TATTATTTTAACGGATCCCCTTGATGGTTCTTCAAATATTGATGTAAACGTATCTGTAGGAACAATTTTCTCTATTTACC
GTCGCGTATCTCCAATTGGCTCACCTGTTACCTTAGAAGATTTTATGCAACCAGGTAATAAACAAGTCGCGGCTGGTTAT
ATTGTTTATGGTTCATCAACTATGTTGGTATATACCACTGGTAATGGGGTTAATGGTTTTACTTATGATCCATCAATCGG
TACATTCTGTCTTTCCCACGAAAATATGCAAATGCCAAAAGAGGGCAAAATTTATTCCATCAATGAAGGACAATACCTCA
AATTCCCACAAGGTGTAAAAAAATATATTAAATATTGCCAAGAAGAAGATAAAGCGACTCATCGCCCTTACGTATCTCGC
TATATTGGTTCACTTGTAGCAGACTTCCACCGCAATTTATTAAAAGGCGGCATTTATATTTACCCAAGTGCAACCAACTA
TCCAAATGGAAAACTCCGTTTATTATATGAAGGCAATCCTATTGCATTTTTAGCGGAGCAAGCTGGTGGTGTCGCAACAG
ATGGTTATCGTCGAATTTTAGATATCGAACCAACCGCACTTCATGAACGTGTTCCACTATTTGTTGGTTCAGAAGATATG
GTAAAAAAAGCACAAGAAATGATGGAAGAATTTAAAGAATAA

Upstream 100 bases:

>100_bases
TTTTTGTGATAAAGATCTCATTCTGATAATCTGCCATTAGAGTTTACACTCCAGATTCCCTATAATTGATCAACGTATTA
TGAAAAACTAAAAGGAAATT

Downstream 100 bases:

>100_bases
TAAAAAGCATCATCTGCTGGTTTTAGCGGCGCAACTTCACGATTTCTATCACGAAAATCACGCTCTTTTATCTCGGCTAA
AATCTGTGCAAAGTTACCAT

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKTLSEFIVERQAEYPNAKGELSGILSSIRLLAKIIHRDINKAGLTNILGQSGIENVQGESQMKLDLFAHNTMKAALMAR
EEVAGFASEEEESFIAFDTERGRNAKYIILTDPLDGSSNIDVNVSVGTIFSIYRRVSPIGSPVTLEDFMQPGNKQVAAGY
IVYGSSTMLVYTTGNGVNGFTYDPSIGTFCLSHENMQMPKEGKIYSINEGQYLKFPQGVKKYIKYCQEEDKATHRPYVSR
YIGSLVADFHRNLLKGGIYIYPSATNYPNGKLRLLYEGNPIAFLAEQAGGVATDGYRRILDIEPTALHERVPLFVGSEDM
VKKAQEMMEEFKE

Sequences:

>Translated_333_residues
MKTLSEFIVERQAEYPNAKGELSGILSSIRLLAKIIHRDINKAGLTNILGQSGIENVQGESQMKLDLFAHNTMKAALMAR
EEVAGFASEEEESFIAFDTERGRNAKYIILTDPLDGSSNIDVNVSVGTIFSIYRRVSPIGSPVTLEDFMQPGNKQVAAGY
IVYGSSTMLVYTTGNGVNGFTYDPSIGTFCLSHENMQMPKEGKIYSINEGQYLKFPQGVKKYIKYCQEEDKATHRPYVSR
YIGSLVADFHRNLLKGGIYIYPSATNYPNGKLRLLYEGNPIAFLAEQAGGVATDGYRRILDIEPTALHERVPLFVGSEDM
VKKAQEMMEEFKE
>Mature_333_residues
MKTLSEFIVERQAEYPNAKGELSGILSSIRLLAKIIHRDINKAGLTNILGQSGIENVQGESQMKLDLFAHNTMKAALMAR
EEVAGFASEEEESFIAFDTERGRNAKYIILTDPLDGSSNIDVNVSVGTIFSIYRRVSPIGSPVTLEDFMQPGNKQVAAGY
IVYGSSTMLVYTTGNGVNGFTYDPSIGTFCLSHENMQMPKEGKIYSINEGQYLKFPQGVKKYIKYCQEEDKATHRPYVSR
YIGSLVADFHRNLLKGGIYIYPSATNYPNGKLRLLYEGNPIAFLAEQAGGVATDGYRRILDIEPTALHERVPLFVGSEDM
VKKAQEMMEEFKE

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI189083692, Length=321, Percent_Identity=43.3021806853583, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI16579888, Length=321, Percent_Identity=43.3021806853583, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI22907028, Length=326, Percent_Identity=41.7177914110429, Blast_Score=240, Evalue=2e-63,
Organism=Escherichia coli, GI1790679, Length=333, Percent_Identity=70.2702702702703, Blast_Score=491, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI17508131, Length=329, Percent_Identity=45.2887537993921, Blast_Score=299, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6323409, Length=323, Percent_Identity=42.1052631578947, Blast_Score=261, Evalue=1e-70,
Organism=Drosophila melanogaster, GI45550998, Length=322, Percent_Identity=47.8260869565217, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI19921562, Length=322, Percent_Identity=47.8260869565217, Blast_Score=283, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146
- InterPro:   IPR020548 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 37078; Mature: 37078

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00124 FBPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLSEFIVERQAEYPNAKGELSGILSSIRLLAKIIHRDINKAGLTNILGQSGIENVQGE
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
SQMKLDLFAHNTMKAALMAREEVAGFASEEEESFIAFDTERGRNAKYIILTDPLDGSSNI
CCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCE
DVNVSVGTIFSIYRRVSPIGSPVTLEDFMQPGNKQVAAGYIVYGSSTMLVYTTGNGVNGF
EEEEEHHHHHHHHHHHCCCCCCEEHHHHHCCCCCEEEEEEEEECCCEEEEEEECCCCCCC
TYDPSIGTFCLSHENMQMPKEGKIYSINEGQYLKFPQGVKKYIKYCQEEDKATHRPYVSR
EECCCCCEEEECCCCCCCCCCCCEEEECCCCEEECCHHHHHHHHHHHHHCCCCCCHHHHH
YIGSLVADFHRNLLKGGIYIYPSATNYPNGKLRLLYEGNPIAFLAEQAGGVATDGYRRIL
HHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCEEE
DIEPTALHERVPLFVGSEDMVKKAQEMMEEFKE
ECCCHHHHCCCCEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTLSEFIVERQAEYPNAKGELSGILSSIRLLAKIIHRDINKAGLTNILGQSGIENVQGE
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
SQMKLDLFAHNTMKAALMAREEVAGFASEEEESFIAFDTERGRNAKYIILTDPLDGSSNI
CCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCE
DVNVSVGTIFSIYRRVSPIGSPVTLEDFMQPGNKQVAAGYIVYGSSTMLVYTTGNGVNGF
EEEEEHHHHHHHHHHHCCCCCCEEHHHHHCCCCCEEEEEEEEECCCEEEEEEECCCCCCC
TYDPSIGTFCLSHENMQMPKEGKIYSINEGQYLKFPQGVKKYIKYCQEEDKATHRPYVSR
EECCCCCEEEECCCCCCCCCCCCEEEECCCCEEECCHHHHHHHHHHHHHCCCCCCHHHHH
YIGSLVADFHRNLLKGGIYIYPSATNYPNGKLRLLYEGNPIAFLAEQAGGVATDGYRRIL
HHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCEEE
DIEPTALHERVPLFVGSEDMVKKAQEMMEEFKE
ECCCHHHHCCCCEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA