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The map label for this gene is dsbE

Identifier: 16273023

GI number: 16273023

Start: 1158694

End: 1159239

Strand: Direct

Name: dsbE

Synonym: HI1095

Alternate gene names: 16273023

Gene position: 1158694-1159239 (Clockwise)

Preceding gene: 16273022

Following gene: 16273642

Centisome position: 63.31

GC content: 34.98

Gene sequence:

>546_bases
ATGAAAAAAAAATTACTCGTTCCTCTTATTCTCTTTTTATCAATAACAATTGCCTTTTTAGTGCAATTAAAACGCAATGC
GCAAGGTGAAGATATTAAAGCATTAGAGTCAGCTTTGGTTGGAAAGCCTGTGCCAGCAAAAAATTTGACGGAGTTGTTTG
AAAATAAAACTTACACGAATGAATTGTTTCAACAAGGTGAGCCAGTTTTGCTTAACGTATGGGCAACTTGGTGTCCGACT
TGTTATGCCGAACATCAATATTTAAACAAACTTGCTAAAGAGGGTGTGAGAATTATCGGTTTAGATTATAAAGATGAATC
ACCTAAAGCAATGAAGTGGTTAAAAGATCTTGGCAATCCTTATCAAGTTGTTTTAAAAGATGAAAAAGGTTCTTTCGGTT
TGGATTTAGGGGTATATGGTGCGCCAGAAACGTTCATTGTAGATGGAAAAGGTGTGATTCATTATCGTTATGCTGGAGAT
GTAAACGAAAAAGTTTGGACTCAGACTTTAAAACCAATTTATGACAAACTTTCGGAGCAACAATAA

Upstream 100 bases:

>100_bases
CCGAAGGGCGGAAGGGGGATTACGTATCCCCCTCAGTCACTTCGCGACAGCTCCCCCCATAAATGGGTGGAGCAAAGTTA
ATGAAAAAGTGCGGTAAAAA

Downstream 100 bases:

>100_bases
TGAAAAAAACATGGCTATTTTTGACCGCACTTTTGTTTAGCTCGGTGGCGTTTTCAGCTATTGATGCATTAAATTTTAGT
TCTCCACAGCAAGAGAGTGA

Product: thiol-disulfide interchange protein

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CcmG

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MKKKLLVPLILFLSITIAFLVQLKRNAQGEDIKALESALVGKPVPAKNLTELFENKTYTNELFQQGEPVLLNVWATWCPT
CYAEHQYLNKLAKEGVRIIGLDYKDESPKAMKWLKDLGNPYQVVLKDEKGSFGLDLGVYGAPETFIVDGKGVIHYRYAGD
VNEKVWTQTLKPIYDKLSEQQ

Sequences:

>Translated_181_residues
MKKKLLVPLILFLSITIAFLVQLKRNAQGEDIKALESALVGKPVPAKNLTELFENKTYTNELFQQGEPVLLNVWATWCPT
CYAEHQYLNKLAKEGVRIIGLDYKDESPKAMKWLKDLGNPYQVVLKDEKGSFGLDLGVYGAPETFIVDGKGVIHYRYAGD
VNEKVWTQTLKPIYDKLSEQQ
>Mature_181_residues
MKKKLLVPLILFLSITIAFLVQLKRNAQGEDIKALESALVGKPVPAKNLTELFENKTYTNELFQQGEPVLLNVWATWCPT
CYAEHQYLNKLAKEGVRIIGLDYKDESPKAMKWLKDLGNPYQVVLKDEKGSFGLDLGVYGAPETFIVDGKGVIHYRYAGD
VNEKVWTQTLKPIYDKLSEQQ

Specific function: Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain

Homologues:

Organism=Escherichia coli, GI1788523, Length=182, Percent_Identity=57.6923076923077, Blast_Score=227, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DSBE_HAEIN (P45038)

Other databases:

- EMBL:   L42023
- PIR:   B64167
- RefSeq:   NP_439252.1
- ProteinModelPortal:   P45038
- SMR:   P45038
- GeneID:   950067
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1095
- TIGR:   HI_1095
- HOGENOM:   HBG493509
- OMA:   CYAEHQF
- ProtClustDB:   CLSK869931
- BioCyc:   HINF71421:HI_1095-MONOMER
- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10
- TIGRFAMs:   TIGR00385

Pfam domain/function: PF08534 Redoxin; SSF52833 Thiordxn-like_fd

EC number: NA

Molecular weight: Translated: 20535; Mature: 20535

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: PS00194 THIOREDOXIN_1; PS51352 THIOREDOXIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc77981c)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKLLVPLILFLSITIAFLVQLKRNAQGEDIKALESALVGKPVPAKNLTELFENKTYTN
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCHHH
ELFQQGEPVLLNVWATWCPTCYAEHQYLNKLAKEGVRIIGLDYKDESPKAMKWLKDLGNP
HHHHCCCCEEEEEHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCC
YQVVLKDEKGSFGLDLGVYGAPETFIVDGKGVIHYRYAGDVNEKVWTQTLKPIYDKLSEQ
EEEEEECCCCCCCCEEECCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCC
Q
H
>Mature Secondary Structure
MKKKLLVPLILFLSITIAFLVQLKRNAQGEDIKALESALVGKPVPAKNLTELFENKTYTN
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCHHH
ELFQQGEPVLLNVWATWCPTCYAEHQYLNKLAKEGVRIIGLDYKDESPKAMKWLKDLGNP
HHHHCCCCEEEEEHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCC
YQVVLKDEKGSFGLDLGVYGAPETFIVDGKGVIHYRYAGDVNEKVWTQTLKPIYDKLSEQ
EEEEEECCCCCCCCEEECCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCC
Q
H

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800