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The map label for this gene is ccmC

Identifier: 16273019

GI number: 16273019

Start: 1155109

End: 1155849

Strand: Direct

Name: ccmC

Synonym: HI1091

Alternate gene names: 16273019

Gene position: 1155109-1155849 (Clockwise)

Preceding gene: 16273018

Following gene: 16273020

Centisome position: 63.12

GC content: 41.16

Gene sequence:

>741_bases
ATGTGGAAGTGGCTACATCCTTATGCAAAACCCGAAACTCAATATCGTATTTGCGGTAAATTGAGTCCGCTATTTGCATT
TTTAACGCTTGTCTTACTCGGTGTTGGCATTGTATGGGGTTTAGCATTCGCCCCAGCAGATTACCAACAAGGTAATAGTT
TCCGAATTATGTATGTACATGCGCCGACAGCGATTTGGTCAATGGGTGTGTACGGTTCAATGGCGATTGCCGCTGTGGTT
GCCCTAGTGTGGCAAATTAAGCAAGCTCATCTCGCAATGATTGCAATGGCACCAATTGGTGCATTGTTTACTTTCTTATC
GCTTGTTACGGGCGCAATTTGGGGGAAACCAATGTGGGGTACTTGGTGGGTGTGGGATGCTCGTTTAACTGCAGAATTAA
TTTTATTCTTTCTTTATCTTGGTATCTTAGCCCTTTATTCTGCTTTTTCAGATCGTAACATAGGGGCAAAAGCGGCGGGG
ATTTTATGTATTACAACGGTCGTGATTTTACCGATTATTCATTTTTCGGTGGAATGGTGGAACACGTTACATCAAGGTGC
GAGTATCACTAAACTGGAAAAACCATCCATTGCAATTCCAATGTTGGTTCCATTAATTTTGTGTATCTTCGGTTTTTTAA
CCTTGTATATTTGGCTTACTTTAGTTCGTTATCGCATGGAATTATTGAAAGAAGATGCAAAACGTCCCTGGGTTAAAGCA
TTAGCTCAAACACTGAAATAA

Upstream 100 bases:

>100_bases
TTTTGCCATCGCGGCAGCGTTGCGAATTAGTTTAGATAATTAATTTTATTCATCGTATAAAAGTGCGGTGGTTTTTCTCT
TTAATTTTTAAGGATTTTTT

Downstream 100 bases:

>100_bases
AGTGCGGTTAGTTTTTAGCGATTTTTTATAAGGAATATTTTATGTTTTTCCAAACTTGGAGTGATTTTTTTAATATGGGT
GGCTACGGTTTTTACGTATG

Product: heme exporter protein C

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmC

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MWKWLHPYAKPETQYRICGKLSPLFAFLTLVLLGVGIVWGLAFAPADYQQGNSFRIMYVHAPTAIWSMGVYGSMAIAAVV
ALVWQIKQAHLAMIAMAPIGALFTFLSLVTGAIWGKPMWGTWWVWDARLTAELILFFLYLGILALYSAFSDRNIGAKAAG
ILCITTVVILPIIHFSVEWWNTLHQGASITKLEKPSIAIPMLVPLILCIFGFLTLYIWLTLVRYRMELLKEDAKRPWVKA
LAQTLK

Sequences:

>Translated_246_residues
MWKWLHPYAKPETQYRICGKLSPLFAFLTLVLLGVGIVWGLAFAPADYQQGNSFRIMYVHAPTAIWSMGVYGSMAIAAVV
ALVWQIKQAHLAMIAMAPIGALFTFLSLVTGAIWGKPMWGTWWVWDARLTAELILFFLYLGILALYSAFSDRNIGAKAAG
ILCITTVVILPIIHFSVEWWNTLHQGASITKLEKPSIAIPMLVPLILCIFGFLTLYIWLTLVRYRMELLKEDAKRPWVKA
LAQTLK
>Mature_246_residues
MWKWLHPYAKPETQYRICGKLSPLFAFLTLVLLGVGIVWGLAFAPADYQQGNSFRIMYVHAPTAIWSMGVYGSMAIAAVV
ALVWQIKQAHLAMIAMAPIGALFTFLSLVTGAIWGKPMWGTWWVWDARLTAELILFFLYLGILALYSAFSDRNIGAKAAG
ILCITTVVILPIIHFSVEWWNTLHQGASITKLEKPSIAIPMLVPLILCIFGFLTLYIWLTLVRYRMELLKEDAKRPWVKA
LAQTLK

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family

Homologues:

Organism=Escherichia coli, GI1788527, Length=241, Percent_Identity=60.1659751037344, Blast_Score=288, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCMC_HAEIN (P45034)

Other databases:

- EMBL:   L42023
- PIR:   G64166
- RefSeq:   NP_439248.1
- GeneID:   950063
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1091
- NMPDR:   fig|71421.1.peg.1048
- TIGR:   HI_1091
- HOGENOM:   HBG589920
- OMA:   ICEILAM
- ProtClustDB:   CLSK869928
- BioCyc:   HINF71421:HI_1091-MONOMER
- InterPro:   IPR002541
- InterPro:   IPR003557
- PRINTS:   PR01386
- TIGRFAMs:   TIGR01191

Pfam domain/function: PF01578 Cytochrom_C_asm

EC number: NA

Molecular weight: Translated: 27717; Mature: 27717

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe03b484)-; HASH(0xdc113ec)-; HASH(0xdcaf688)-; HASH(0xda7f318)-; HASH(0xdf48e90)-; HASH(0xb464d80)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCH
>Mature Secondary Structure
MWKWLHPYAKPETQYRICGKLSPLFAFLTLVLLGVGIVWGLAFAPADYQQGNSFRIMYVH
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
APTAIWSMGVYGSMAIAAVVALVWQIKQAHLAMIAMAPIGALFTFLSLVTGAIWGKPMWG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TWWVWDARLTAELILFFLYLGILALYSAFSDRNIGAKAAGILCITTVVILPIIHFSVEWW
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NTLHQGASITKLEKPSIAIPMLVPLILCIFGFLTLYIWLTLVRYRMELLKEDAKRPWVKA
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LAQTLK
HHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800