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The map label for this gene is dipZ [H]

Identifier: 16272825

GI number: 16272825

Start: 937413

End: 939152

Strand: Direct

Name: dipZ [H]

Synonym: HI0885

Alternate gene names: 16272825

Gene position: 937413-939152 (Clockwise)

Preceding gene: 16272822

Following gene: 16272826

Centisome position: 51.22

GC content: 37.64

Gene sequence:

>1740_bases
ATGAAAAAACTCTTTCTTTTTTTTACGCTGATTTTCACCGCTTTTGCGGCTAATTCAGGTTTATTCGATAAAAAACAAAC
CTTTTTAAAAGTAGATGATGCTTTTGCTTTTTCTGCTACTTTATCTACAGATAAAAGCCAGTTACAAGCCCATTGGGATA
TTGCCGATGGCTATTATTTGTATCAAGATAAAATTAGTGCTGAGTTAGTCGGTAAATCAAATCCTCTCTCTTTACATACC
CAACAAGCGGCGGAATTACATCAAGATCCTTATTTTGGCGAAGTAAAAGTTTTTACTCACTCAATTGATGGCATATTTAG
GGGTGCATTTAATAATGCTGATGATAAGGTTGAAATCACTTATCAAGGATGTACCGAAGGTTTTTGCTATCCGCCTGAAA
CTAAAGTATTACGAATTGGGGATTTAGTCGTTTCTCAAAAGCAAATTGTCGAAAAAACAGTTGAAAAAAATACCGCACTT
TTATCTGAACAAGATCGTTTAGCTGATGGTTTATTCCATAGTAAATGGGCAATTTTTGGTTTCTTTGTATTAGGATTGGG
ACTGGCTTTTACGCCTTGCGTATTGCCAATGTTACCGTTGCTTTCTGCTATTGTTATCGGTCAGCAACAACGTCCAAATA
TGATGCGAGCGTTTAGTTTAGCTTTTCTTTATGTTCAAGGCATGGCTCTGACTTACACTTTGTTAGGGCTTGCAGTGGCA
GCCATCGGTTTACCGTTCCAAATCGCTTTGCAACATCCTTATGTGATGATAGGGCTTTCTATTTTATTTGTTGCTCTTGC
CCTTTCAATGTTTGGGTTATTTACTATTCAATTGCCAAATAGCTTACAAAATAAACTCAATACATGGAGCCAAAAACAAA
CCTCGGGTGCTTTTGGCGGAGCCTTTGCAATGGGAATGATTGCTGGGCTGGTGGCATCGCCTTGTACATCTGCGCCACTT
TCTGGTGCTTTACTTTATGTGGCACAAAGTGGCGATTTATTTACAGGCGCAGTAACCCTTTATTTGCTCGCACTTGGTAT
GGGCGTGCCGCTAATGTTAATCACATTGTTTGGTAATAAAATTTTGCCCAAATCAGGTGAGTGGATGAATACCGTAAAAC
AAACATTCGGCTTTGTGATGTTGGCGTTACCTGTATTTTTACTTTCTCGTATTTTGCCTGAAGTATGGGAGCCACGCTTA
TGGGCTGGATTAGCGACAGTATTTTTTATTTGGTTTGCGTTGCAGATGTCTAAGAACGGTTTTGGCTATGCTATTAAAAT
TATTAGTTTTGCGTTGGCTATGGTTACTGTACAACCCCTGCAAAATTGGATTTGGCAAACTCAAACTACAACACAAAGTG
CGGTAGAAAATATGCCTGTTTCTCAAGTTAAATTTAAGCAAATTAAAAATACTGAAGAACTTGACCGCACTTTAGCGGAA
AATCCGCATTCAATTGCTATGTTGGATTTATACGCGGATTGGTGTGTTGCTTGTAAAGAATTTGAAAAGCTGACGTTTTC
AGATCCACAAGTGCAACAGCAATTTCAAAATATCTTATTGTTACAAGTGAGTATGACAAAGAATAGCCCAGAAAATAAAG
CATTAATGGAACGCTTTAATGTGATGGGATTGCCTACGATTTTATTTTTTGATCAGCAAAATAATGAAATTAAAGGAAGT
AGAGTAACGGGCTTTATGGATGCTGATGCTTTTTCTAATTGGATTGAAAAGCTACTTTAG

Upstream 100 bases:

>100_bases
TTTTACCTGATTTTCCTTTTTGTGATCTAAATCATAGTTTTAGGTATTCAAATTTCTTTGTGATAGAATTTCGAGCATCT
ATATTTTTATACTCAATTCT

Downstream 100 bases:

>100_bases
TTATTTTTTACTTTTGGTAAAAAGTATTTTTCAATTTTAATTATTGTTTAACTACCCGTTAAAGATTAATATGACGCCGT
TTTAATTCATCTTTAAACAA

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MKKLFLFFTLIFTAFAANSGLFDKKQTFLKVDDAFAFSATLSTDKSQLQAHWDIADGYYLYQDKISAELVGKSNPLSLHT
QQAAELHQDPYFGEVKVFTHSIDGIFRGAFNNADDKVEITYQGCTEGFCYPPETKVLRIGDLVVSQKQIVEKTVEKNTAL
LSEQDRLADGLFHSKWAIFGFFVLGLGLAFTPCVLPMLPLLSAIVIGQQQRPNMMRAFSLAFLYVQGMALTYTLLGLAVA
AIGLPFQIALQHPYVMIGLSILFVALALSMFGLFTIQLPNSLQNKLNTWSQKQTSGAFGGAFAMGMIAGLVASPCTSAPL
SGALLYVAQSGDLFTGAVTLYLLALGMGVPLMLITLFGNKILPKSGEWMNTVKQTFGFVMLALPVFLLSRILPEVWEPRL
WAGLATVFFIWFALQMSKNGFGYAIKIISFALAMVTVQPLQNWIWQTQTTTQSAVENMPVSQVKFKQIKNTEELDRTLAE
NPHSIAMLDLYADWCVACKEFEKLTFSDPQVQQQFQNILLLQVSMTKNSPENKALMERFNVMGLPTILFFDQQNNEIKGS
RVTGFMDADAFSNWIEKLL

Sequences:

>Translated_579_residues
MKKLFLFFTLIFTAFAANSGLFDKKQTFLKVDDAFAFSATLSTDKSQLQAHWDIADGYYLYQDKISAELVGKSNPLSLHT
QQAAELHQDPYFGEVKVFTHSIDGIFRGAFNNADDKVEITYQGCTEGFCYPPETKVLRIGDLVVSQKQIVEKTVEKNTAL
LSEQDRLADGLFHSKWAIFGFFVLGLGLAFTPCVLPMLPLLSAIVIGQQQRPNMMRAFSLAFLYVQGMALTYTLLGLAVA
AIGLPFQIALQHPYVMIGLSILFVALALSMFGLFTIQLPNSLQNKLNTWSQKQTSGAFGGAFAMGMIAGLVASPCTSAPL
SGALLYVAQSGDLFTGAVTLYLLALGMGVPLMLITLFGNKILPKSGEWMNTVKQTFGFVMLALPVFLLSRILPEVWEPRL
WAGLATVFFIWFALQMSKNGFGYAIKIISFALAMVTVQPLQNWIWQTQTTTQSAVENMPVSQVKFKQIKNTEELDRTLAE
NPHSIAMLDLYADWCVACKEFEKLTFSDPQVQQQFQNILLLQVSMTKNSPENKALMERFNVMGLPTILFFDQQNNEIKGS
RVTGFMDADAFSNWIEKLL
>Mature_579_residues
MKKLFLFFTLIFTAFAANSGLFDKKQTFLKVDDAFAFSATLSTDKSQLQAHWDIADGYYLYQDKISAELVGKSNPLSLHT
QQAAELHQDPYFGEVKVFTHSIDGIFRGAFNNADDKVEITYQGCTEGFCYPPETKVLRIGDLVVSQKQIVEKTVEKNTAL
LSEQDRLADGLFHSKWAIFGFFVLGLGLAFTPCVLPMLPLLSAIVIGQQQRPNMMRAFSLAFLYVQGMALTYTLLGLAVA
AIGLPFQIALQHPYVMIGLSILFVALALSMFGLFTIQLPNSLQNKLNTWSQKQTSGAFGGAFAMGMIAGLVASPCTSAPL
SGALLYVAQSGDLFTGAVTLYLLALGMGVPLMLITLFGNKILPKSGEWMNTVKQTFGFVMLALPVFLLSRILPEVWEPRL
WAGLATVFFIWFALQMSKNGFGYAIKIISFALAMVTVQPLQNWIWQTQTTTQSAVENMPVSQVKFKQIKNTEELDRTLAE
NPHSIAMLDLYADWCVACKEFEKLTFSDPQVQQQFQNILLLQVSMTKNSPENKALMERFNVMGLPTILFFDQQNNEIKGS
RVTGFMDADAFSNWIEKLL

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=578, Percent_Identity=47.0588235294118, Blast_Score=512, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 64407; Mature: 64407

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFLFFTLIFTAFAANSGLFDKKQTFLKVDDAFAFSATLSTDKSQLQAHWDIADGYYL
CCHHHHHHHHHHHHHHCCCCCCCCHHHHEEECCCCEEEEECCCCHHHHHEEEECCCCEEE
YQDKISAELVGKSNPLSLHTQQAAELHQDPYFGEVKVFTHSIDGIFRGAFNNADDKVEIT
EECCCCHHCCCCCCCCEEEHHHHHHHHCCCCCCEEEEEEEHHHHHHHCCCCCCCCEEEEE
YQGCTEGFCYPPETKVLRIGDLVVSQKQIVEKTVEKNTALLSEQDRLADGLFHSKWAIFG
EECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFVLGLGLAFTPCVLPMLPLLSAIVIGQQQRPNMMRAFSLAFLYVQGMALTYTLLGLAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGLPFQIALQHPYVMIGLSILFVALALSMFGLFTIQLPNSLQNKLNTWSQKQTSGAFGG
HHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHCCCCCHH
AFAMGMIAGLVASPCTSAPLSGALLYVAQSGDLFTGAVTLYLLALGMGVPLMLITLFGNK
HHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCC
ILPKSGEWMNTVKQTFGFVMLALPVFLLSRILPEVWEPRLWAGLATVFFIWFALQMSKNG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
FGYAIKIISFALAMVTVQPLQNWIWQTQTTTQSAVENMPVSQVKFKQIKNTEELDRTLAE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHC
NPHSIAMLDLYADWCVACKEFEKLTFSDPQVQQQFQNILLLQVSMTKNSPENKALMERFN
CCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHC
VMGLPTILFFDQQNNEIKGSRVTGFMDADAFSNWIEKLL
CCCCCEEEEEECCCCCCCCCEEEEEECHHHHHHHHHHHC
>Mature Secondary Structure
MKKLFLFFTLIFTAFAANSGLFDKKQTFLKVDDAFAFSATLSTDKSQLQAHWDIADGYYL
CCHHHHHHHHHHHHHHCCCCCCCCHHHHEEECCCCEEEEECCCCHHHHHEEEECCCCEEE
YQDKISAELVGKSNPLSLHTQQAAELHQDPYFGEVKVFTHSIDGIFRGAFNNADDKVEIT
EECCCCHHCCCCCCCCEEEHHHHHHHHCCCCCCEEEEEEEHHHHHHHCCCCCCCCEEEEE
YQGCTEGFCYPPETKVLRIGDLVVSQKQIVEKTVEKNTALLSEQDRLADGLFHSKWAIFG
EECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFVLGLGLAFTPCVLPMLPLLSAIVIGQQQRPNMMRAFSLAFLYVQGMALTYTLLGLAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGLPFQIALQHPYVMIGLSILFVALALSMFGLFTIQLPNSLQNKLNTWSQKQTSGAFGG
HHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHCCCCCHH
AFAMGMIAGLVASPCTSAPLSGALLYVAQSGDLFTGAVTLYLLALGMGVPLMLITLFGNK
HHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCC
ILPKSGEWMNTVKQTFGFVMLALPVFLLSRILPEVWEPRLWAGLATVFFIWFALQMSKNG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
FGYAIKIISFALAMVTVQPLQNWIWQTQTTTQSAVENMPVSQVKFKQIKNTEELDRTLAE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHC
NPHSIAMLDLYADWCVACKEFEKLTFSDPQVQQQFQNILLLQVSMTKNSPENKALMERFN
CCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHC
VMGLPTILFFDQQNNEIKGSRVTGFMDADAFSNWIEKLL
CCCCCEEEEEECCCCCCCCCEEEEEECHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA