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The map label for this gene is gpmA [H]

Identifier: 16272698

GI number: 16272698

Start: 821450

End: 822133

Strand: Direct

Name: gpmA [H]

Synonym: HI0757

Alternate gene names: 16272698

Gene position: 821450-822133 (Clockwise)

Preceding gene: 16272695

Following gene: 16272700

Centisome position: 44.88

GC content: 37.13

Gene sequence:

>684_bases
ATGGAATTAGTATTTATCCGTCACGGTTTTAGTGAATGGAATGCGAAAAACTTATTCACAGGCTGGCGTGATGTGAATTT
AACTGAACGTGGTGTGGAAGAAGCAAAAACTGCGGGTAAAAAACTGTTAGACAAAGGTTATGAATTTGATATCGCATTTA
CCTCTGTTTTAACTCGAGCAATCAAAACTTGTAACATCGTGTTAGAAGAATCCCATCAATTATGGATTCCGCAAGTAAAA
AACTGGCGTTTAAATGAACGTCATTATGGTGCTTTACAAGGTTTAGATAAAAAAGCGACTGCGGAGCAATACGGTGACGA
ACAAGTTCATATTTGGCGTCGTTCTTACGACATTTCTCCACCAGATTTAGATCCACAAGATCCAAATTCTGCACACAATG
ACCGTCGCTACGCAAATATTCCATCTGATGTTGTGCCAAACGCAGAAAATTTAAAATTAACATTAGAACGTGCATTACCA
TTCTGGGAAGATCAAATTGCACCAGCAATGCTTTCTGGCAAACGTGTTTTAGTGGTTGCTCACGGAAATTCACTTCGTGC
GTTGGCAAAACATATTATCGGTATTTCTGATGCTGAAATTATGGATTTTGAAATTCCAACAGGCCAACCTTTAGTATTAA
AACTAGATGATAAATTAAATTACGTAGAACATTACTATCTTTAA

Upstream 100 bases:

>100_bases
TTGCTAAAGATCAGGAAATCATCCCTTTTAACTTTTAAAGCTAAGGATTTTTTGCTATAAAATGTGCGTTCTTTTTATTT
GAAAAAATTAGGAGATTCTT

Downstream 100 bases:

>100_bases
TTAAGTTCAACGTATTGTTGTTCTAACTGTATAAAACAAAACCCCGCAAATTAGCGGGGTTTTTAAGCAAGTCCAAATTA
TTTTGTGCTTGGAATTTTGA

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MELVFIRHGFSEWNAKNLFTGWRDVNLTERGVEEAKTAGKKLLDKGYEFDIAFTSVLTRAIKTCNIVLEESHQLWIPQVK
NWRLNERHYGALQGLDKKATAEQYGDEQVHIWRRSYDISPPDLDPQDPNSAHNDRRYANIPSDVVPNAENLKLTLERALP
FWEDQIAPAMLSGKRVLVVAHGNSLRALAKHIIGISDAEIMDFEIPTGQPLVLKLDDKLNYVEHYYL

Sequences:

>Translated_227_residues
MELVFIRHGFSEWNAKNLFTGWRDVNLTERGVEEAKTAGKKLLDKGYEFDIAFTSVLTRAIKTCNIVLEESHQLWIPQVK
NWRLNERHYGALQGLDKKATAEQYGDEQVHIWRRSYDISPPDLDPQDPNSAHNDRRYANIPSDVVPNAENLKLTLERALP
FWEDQIAPAMLSGKRVLVVAHGNSLRALAKHIIGISDAEIMDFEIPTGQPLVLKLDDKLNYVEHYYL
>Mature_227_residues
MELVFIRHGFSEWNAKNLFTGWRDVNLTERGVEEAKTAGKKLLDKGYEFDIAFTSVLTRAIKTCNIVLEESHQLWIPQVK
NWRLNERHYGALQGLDKKATAEQYGDEQVHIWRRSYDISPPDLDPQDPNSAHNDRRYANIPSDVVPNAENLKLTLERALP
FWEDQIAPAMLSGKRVLVVAHGNSLRALAKHIIGISDAEIMDFEIPTGQPLVLKLDDKLNYVEHYYL

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=220, Percent_Identity=51.8181818181818, Blast_Score=246, Evalue=9e-66,
Organism=Homo sapiens, GI4505753, Length=224, Percent_Identity=52.2321428571429, Blast_Score=234, Evalue=3e-62,
Organism=Homo sapiens, GI4502445, Length=225, Percent_Identity=48.4444444444444, Blast_Score=230, Evalue=8e-61,
Organism=Homo sapiens, GI40353764, Length=225, Percent_Identity=48.4444444444444, Blast_Score=230, Evalue=8e-61,
Organism=Homo sapiens, GI71274132, Length=224, Percent_Identity=50.4464285714286, Blast_Score=224, Evalue=6e-59,
Organism=Homo sapiens, GI310129614, Length=161, Percent_Identity=54.0372670807453, Blast_Score=167, Evalue=5e-42,
Organism=Escherichia coli, GI1786970, Length=226, Percent_Identity=52.6548672566372, Blast_Score=253, Evalue=7e-69,
Organism=Saccharomyces cerevisiae, GI6322697, Length=227, Percent_Identity=51.5418502202643, Blast_Score=243, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6324516, Length=280, Percent_Identity=31.4285714285714, Blast_Score=125, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6320183, Length=282, Percent_Identity=30.4964539007092, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6324857, Length=108, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646216, Length=221, Percent_Identity=49.7737556561086, Blast_Score=222, Evalue=1e-58,
Organism=Drosophila melanogaster, GI85725270, Length=224, Percent_Identity=51.7857142857143, Blast_Score=216, Evalue=1e-56,
Organism=Drosophila melanogaster, GI85725272, Length=224, Percent_Identity=51.7857142857143, Blast_Score=216, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24650981, Length=224, Percent_Identity=51.7857142857143, Blast_Score=216, Evalue=1e-56,
Organism=Drosophila melanogaster, GI28571815, Length=219, Percent_Identity=38.8127853881278, Blast_Score=164, Evalue=4e-41,
Organism=Drosophila melanogaster, GI24648979, Length=219, Percent_Identity=38.8127853881278, Blast_Score=164, Evalue=4e-41,
Organism=Drosophila melanogaster, GI28571817, Length=219, Percent_Identity=38.8127853881278, Blast_Score=164, Evalue=4e-41,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 26049; Mature: 26049

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELVFIRHGFSEWNAKNLFTGWRDVNLTERGVEEAKTAGKKLLDKGYEFDIAFTSVLTRA
CEEEEEECCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHH
IKTCNIVLEESHQLWIPQVKNWRLNERHYGALQGLDKKATAEQYGDEQVHIWRRSYDISP
HHHHHEEEECCCCEECCCCCCCCCCCCHHHHHHCCCCHHHHHHCCCCEEEEEEEECCCCC
PDLDPQDPNSAHNDRRYANIPSDVVPNAENLKLTLERALPFWEDQIAPAMLSGKRVLVVA
CCCCCCCCCCCCCCCEECCCCHHHCCCCCCEEEEHHHCCCCCHHHCCHHHHCCCEEEEEE
HGNSLRALAKHIIGISDAEIMDFEIPTGQPLVLKLDDKLNYVEHYYL
CCCCHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCCCCHHHHCC
>Mature Secondary Structure
MELVFIRHGFSEWNAKNLFTGWRDVNLTERGVEEAKTAGKKLLDKGYEFDIAFTSVLTRA
CEEEEEECCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHH
IKTCNIVLEESHQLWIPQVKNWRLNERHYGALQGLDKKATAEQYGDEQVHIWRRSYDISP
HHHHHEEEECCCCEECCCCCCCCCCCCHHHHHHCCCCHHHHHHCCCCEEEEEEEECCCCC
PDLDPQDPNSAHNDRRYANIPSDVVPNAENLKLTLERALPFWEDQIAPAMLSGKRVLVVA
CCCCCCCCCCCCCCCEECCCCHHHCCCCCCEEEEHHHCCCCCHHHCCHHHHCCCEEEEEE
HGNSLRALAKHIIGISDAEIMDFEIPTGQPLVLKLDDKLNYVEHYYL
CCCCHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA