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The map label for this gene is yhjE [C]

Identifier: 16272237

GI number: 16272237

Start: 314478

End: 315794

Strand: Reverse

Name: yhjE [C]

Synonym: HI0281

Alternate gene names: 16272237

Gene position: 315794-314478 (Counterclockwise)

Preceding gene: 16272238

Following gene: 16272235

Centisome position: 17.26

GC content: 39.56

Gene sequence:

>1317_bases
ATGTCTACACAACTTCGTAATAATCCGATGAAAGTGGCGTTAGCCTCGATGGTCGGTACAGCAATCGAATTTTTTGATTA
TTATATCTATGCGGCTGCCGCTGTATTAGTTTTCAATACGCAATTCTTTCATAGCGATGATCCGCTTTCTAATGATTTAC
TTTCTCTTTCTACGCTTGCTTTAGCATTCTTTGCACGTCCTATTGGTTCGGCATTATTCGGTCACTTTGGCGATAAAATT
GGTCGTAAAAAAACCTTGGTTGCCTCTCTTGTTTTAATGGGTGGTTCAACGGTAGTAATTGGTTTACTTCCTAATTATGC
TCAAATTGGTATCTGGGCGCCGATTTTGCTTTGCGTATGCCGTGTTGGTCAAGGTATTGGGCTTGGGGGCGAATGGGGCG
GTGCAGCGTTAGTCGCAACAGAAAATGCACCAGAAGGAAAACGAGCTTGGTACGGTACTTTCCCTCAATTAGGCGCACCA
ATTGGTTTATTTGTCGCTAATGGAACGTTCTTCTTAGTTAGCTATTTGCTTGGTCATAATGCACTTGTTGAATGGGCGTG
GCGTATTCCATTTGTATCTTCCATTTTATTAGTTGCAGTTGGTTTATATGTTCGCTTAACTTTGCACGAAAGCCACGTAT
TTGTGGAAGCAGAGCAAAAAGGCAAAAAATTGAATGCACCAGTGAGTGTTGTGTTTACCAAACACTTAAAACCAATGGTT
ATTGGCACATTTATTATGGTGGCAACTTATTCTCTGTTTTACATTATGACGGCTTTTGCGCAGGCATATTCTCGAACAGC
ACCAAAGCTTTCTGAAGCAGGTTATGCACTTGGTTTAGGAATCCCAGCAAATACATTTACTGGCTTGTTATTAATTAGTG
CCATTGTATTTGGTATTTTTATCAGTATTTCCGGTTTTTATGCCGATAAAATCGGTCGTCGTAAATGGTTGATTTGGGTG
ACTATTGCTATCGGCGTGCTTGGTTTAGCAATGCCGTTATTCTTAGAAAATGGCACTCCAGTTAGCGTATTTGCATTTTT
AGTGATTGGTATGGCGATTATGGGAATGACATTTGGTCCAATGGCTGCGCTATTACCAGAATTATTCCCAACAGAAGTCC
GTTATTCAGGTGCCTCTCTTGCGTATAATTTAGCATCAATTATTGGTGCAACAATTGCAGCAATGATTTCTTTAAAAATT
AACGCGTCATTCGGTGTAATGGGTGTAGGAATTTATTTAGCAATCAATGCATTAATGACTTTCTTGGCATTATTAGCCTC
AAAAGAGACTAAAAATGTAGATTTAACAGAAATCTAA

Upstream 100 bases:

>100_bases
TCTAAAAAAATAGAAAATTGCATATTAAAAATTGTTAGACCTTAGTTAAAATGCTAGGATTCAATCCTTTCTCTTTATAA
TAAACTTCTAAGGAAACACA

Downstream 100 bases:

>100_bases
TTTTAGTCGTAAATATTTTAGGTTATTTAGCCTTTAGAAGTAGTTTATTTAGAACTTATATCAAGTTTAGGTTTCAATGC
CAACAAGTAAATAGACTACT

Product: transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MSTQLRNNPMKVALASMVGTAIEFFDYYIYAAAAVLVFNTQFFHSDDPLSNDLLSLSTLALAFFARPIGSALFGHFGDKI
GRKKTLVASLVLMGGSTVVIGLLPNYAQIGIWAPILLCVCRVGQGIGLGGEWGGAALVATENAPEGKRAWYGTFPQLGAP
IGLFVANGTFFLVSYLLGHNALVEWAWRIPFVSSILLVAVGLYVRLTLHESHVFVEAEQKGKKLNAPVSVVFTKHLKPMV
IGTFIMVATYSLFYIMTAFAQAYSRTAPKLSEAGYALGLGIPANTFTGLLLISAIVFGIFISISGFYADKIGRRKWLIWV
TIAIGVLGLAMPLFLENGTPVSVFAFLVIGMAIMGMTFGPMAALLPELFPTEVRYSGASLAYNLASIIGATIAAMISLKI
NASFGVMGVGIYLAINALMTFLALLASKETKNVDLTEI

Sequences:

>Translated_438_residues
MSTQLRNNPMKVALASMVGTAIEFFDYYIYAAAAVLVFNTQFFHSDDPLSNDLLSLSTLALAFFARPIGSALFGHFGDKI
GRKKTLVASLVLMGGSTVVIGLLPNYAQIGIWAPILLCVCRVGQGIGLGGEWGGAALVATENAPEGKRAWYGTFPQLGAP
IGLFVANGTFFLVSYLLGHNALVEWAWRIPFVSSILLVAVGLYVRLTLHESHVFVEAEQKGKKLNAPVSVVFTKHLKPMV
IGTFIMVATYSLFYIMTAFAQAYSRTAPKLSEAGYALGLGIPANTFTGLLLISAIVFGIFISISGFYADKIGRRKWLIWV
TIAIGVLGLAMPLFLENGTPVSVFAFLVIGMAIMGMTFGPMAALLPELFPTEVRYSGASLAYNLASIIGATIAAMISLKI
NASFGVMGVGIYLAINALMTFLALLASKETKNVDLTEI
>Mature_437_residues
STQLRNNPMKVALASMVGTAIEFFDYYIYAAAAVLVFNTQFFHSDDPLSNDLLSLSTLALAFFARPIGSALFGHFGDKIG
RKKTLVASLVLMGGSTVVIGLLPNYAQIGIWAPILLCVCRVGQGIGLGGEWGGAALVATENAPEGKRAWYGTFPQLGAPI
GLFVANGTFFLVSYLLGHNALVEWAWRIPFVSSILLVAVGLYVRLTLHESHVFVEAEQKGKKLNAPVSVVFTKHLKPMVI
GTFIMVATYSLFYIMTAFAQAYSRTAPKLSEAGYALGLGIPANTFTGLLLISAIVFGIFISISGFYADKIGRRKWLIWVT
IAIGVLGLAMPLFLENGTPVSVFAFLVIGMAIMGMTFGPMAALLPELFPTEVRYSGASLAYNLASIIGATIAAMISLKIN
ASFGVMGVGIYLAINALMTFLALLASKETKNVDLTEI

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family

Homologues:

Organism=Escherichia coli, GI1789941, Length=430, Percent_Identity=54.8837209302326, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1788292, Length=438, Percent_Identity=33.1050228310502, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1790550, Length=433, Percent_Identity=30.0230946882217, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1788942, Length=420, Percent_Identity=29.0476190476191, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI87082404, Length=426, Percent_Identity=25.5868544600939, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI87082231, Length=394, Percent_Identity=24.1116751269036, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y281_HAEIN (P44610)

Other databases:

- EMBL:   L42023
- PIR:   A64147
- RefSeq:   NP_438449.1
- ProteinModelPortal:   P44610
- GeneID:   950652
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0281
- NMPDR:   fig|71421.1.peg.264
- TIGR:   HI_0281
- HOGENOM:   HBG757988
- OMA:   TIAAMIS
- ProtClustDB:   CLSK789715
- BioCyc:   HINF71421:HI_0281-MONOMER
- InterPro:   IPR004736
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- TIGRFAMs:   TIGR00883

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 46900; Mature: 46769

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50850 MFS; PS00216 SUGAR_TRANSPORT_1; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb6c8304)-; HASH(0x405a347c)-; HASH(0xc8c9cb0)-; HASH(0xc87f6b8)-; HASH(0x405a200c)-; HASH(0xcafff2c)-; HASH(0xbb915b4)-; HASH(0x9474348)-; HASH(0xb1acbb4)-; HASH(0xc8a7260)-; HASH(0xae63448)-; HASH(0xc0ae3fc)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQLRNNPMKVALASMVGTAIEFFDYYIYAAAAVLVFNTQFFHSDDPLSNDLLSLSTLA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LAFFARPIGSALFGHFGDKIGRKKTLVASLVLMGGSTVVIGLLPNYAQIGIWAPILLCVC
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHH
RVGQGIGLGGEWGGAALVATENAPEGKRAWYGTFPQLGAPIGLFVANGTFFLVSYLLGHN
HCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHCCCEEEEEECCHHHHHHHHHCCH
ALVEWAWRIPFVSSILLVAVGLYVRLTLHESHVFVEAEQKGKKLNAPVSVVFTKHLKPMV
HHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEEEEEHHCCCCCCCCEEEEEHHHCCHHH
IGTFIMVATYSLFYIMTAFAQAYSRTAPKLSEAGYALGLGIPANTFTGLLLISAIVFGIF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEECCCCHHHHHHHHHHHHHHHHHH
ISISGFYADKIGRRKWLIWVTIAIGVLGLAMPLFLENGTPVSVFAFLVIGMAIMGMTFGP
HHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCH
MAALLPELFPTEVRYSGASLAYNLASIIGATIAAMISLKINASFGVMGVGIYLAINALMT
HHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHH
FLALLASKETKNVDLTEI
HHHHHHCCCCCCCCCCCH
>Mature Secondary Structure 
STQLRNNPMKVALASMVGTAIEFFDYYIYAAAAVLVFNTQFFHSDDPLSNDLLSLSTLA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LAFFARPIGSALFGHFGDKIGRKKTLVASLVLMGGSTVVIGLLPNYAQIGIWAPILLCVC
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHH
RVGQGIGLGGEWGGAALVATENAPEGKRAWYGTFPQLGAPIGLFVANGTFFLVSYLLGHN
HCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHCCCEEEEEECCHHHHHHHHHCCH
ALVEWAWRIPFVSSILLVAVGLYVRLTLHESHVFVEAEQKGKKLNAPVSVVFTKHLKPMV
HHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEEEEEHHCCCCCCCCEEEEEHHHCCHHH
IGTFIMVATYSLFYIMTAFAQAYSRTAPKLSEAGYALGLGIPANTFTGLLLISAIVFGIF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEECCCCHHHHHHHHHHHHHHHHHH
ISISGFYADKIGRRKWLIWVTIAIGVLGLAMPLFLENGTPVSVFAFLVIGMAIMGMTFGP
HHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCH
MAALLPELFPTEVRYSGASLAYNLASIIGATIAAMISLKINASFGVMGVGIYLAINALMT
HHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHH
FLALLASKETKNVDLTEI
HHHHHHCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800