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The map label for this gene is murB [H]

Identifier: 16272226

GI number: 16272226

Start: 301840

End: 302865

Strand: Direct

Name: murB [H]

Synonym: HI0268

Alternate gene names: 16272226

Gene position: 301840-302865 (Clockwise)

Preceding gene: 16272225

Following gene: 16272227

Centisome position: 16.49

GC content: 38.3

Gene sequence:

>1026_bases
ATGCAAAATTTACAACCTTTTCACACTTTCCACATTCAGTCTAATGCTCGTGAAATTATTGAAGCACATAGTATCGAACA
GCTACAACAAGTGTGGGCGAATTCTAAATCAGAAAATTTACCCACTCTTTTTTTAGGTCAAGGAAGTAATGTTCTATTTC
TAGATGATTTTAATGGCATCGTGATCCTTAATCGTTTAATGGGGATTACGCACGAACAAGATGCAAATTTTCACTATCTT
CACGTCAATGGCGGGGAAAATTGGCATAAATTGGTGGAGTGGTCTATTAATAATGGTATTTATGGCTTAGAAAATCTGGC
TCTGATTCCCGGTTGTGCAGGCTCTGCCCCCATTCAAAATATCGGTGCTTATGGCGTTGAATTTAAAGATGTATGTGATT
ATGTGGAGGTACTTAATTTAAATACGAACGAAACCTTTAGACTCGACACAGAACAATGTGAATTTGGTTATCGTGAGAGT
ATTTTTAAACATCGTTATCAGCAAGGTTATGTGATTACAGCGGTTGGATTAAAGCTAAAAAAAGATTGGCAGCCTATTCT
AAAATATGGTTCGCTTGTAGAGTTCGATCCGAAAACGGTCACCGCTAAACAAATTTTTGATGAAGTCTGTCATATCCGTC
AAAGCAAATTACCTGACCCAAATGAAGTGGGTAATGCAGGGAGTTTCTTTAAAAATCCCGTTGTCAGTTCAGAACATTTT
GAAGAAATCAAAAAACATCACGAAAATCTACCGCACTTTCCACAGGCAGATGGCTCAGTGAAATTAGCGGCAGGCTGGCT
GATTGATCAATGCAATCTTAAAGGTTTTCAAATTGGTGGGGCTGCGGTTCATAAAAAACAAGCATTAGTATTAATTAACA
AAAACGGGGCAACAGGGCAAGACGTGGTCAAACTCGCCCATCACGTTCGCCAAACTGTTGCAGAAAAATTTGGTGTATAT
TTACAACCTGAAGTACGATTTATCAGTGCAACTGGCGAAGTAAATAGTGAGCAAATTATCACGTAA

Upstream 100 bases:

>100_bases
TTGTCGTCAGCTTAATGCACAATTGCATATTCATCGCCGTGAACAAGGCGGCACACAAGTCAAAATTACCTTGCCACATA
CATTATATTAGGACATCAAA

Downstream 100 bases:

>100_bases
TTTTATAATAATTGAACTTTCAATTGATAAAATCTGTCTTATTAACAAATTGGTTCAATAAGATAGCTTATTGTGCTATA
ACTAGGTACATTGATTGGCA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MQNLQPFHTFHIQSNAREIIEAHSIEQLQQVWANSKSENLPTLFLGQGSNVLFLDDFNGIVILNRLMGITHEQDANFHYL
HVNGGENWHKLVEWSINNGIYGLENLALIPGCAGSAPIQNIGAYGVEFKDVCDYVEVLNLNTNETFRLDTEQCEFGYRES
IFKHRYQQGYVITAVGLKLKKDWQPILKYGSLVEFDPKTVTAKQIFDEVCHIRQSKLPDPNEVGNAGSFFKNPVVSSEHF
EEIKKHHENLPHFPQADGSVKLAAGWLIDQCNLKGFQIGGAAVHKKQALVLINKNGATGQDVVKLAHHVRQTVAEKFGVY
LQPEVRFISATGEVNSEQIIT

Sequences:

>Translated_341_residues
MQNLQPFHTFHIQSNAREIIEAHSIEQLQQVWANSKSENLPTLFLGQGSNVLFLDDFNGIVILNRLMGITHEQDANFHYL
HVNGGENWHKLVEWSINNGIYGLENLALIPGCAGSAPIQNIGAYGVEFKDVCDYVEVLNLNTNETFRLDTEQCEFGYRES
IFKHRYQQGYVITAVGLKLKKDWQPILKYGSLVEFDPKTVTAKQIFDEVCHIRQSKLPDPNEVGNAGSFFKNPVVSSEHF
EEIKKHHENLPHFPQADGSVKLAAGWLIDQCNLKGFQIGGAAVHKKQALVLINKNGATGQDVVKLAHHVRQTVAEKFGVY
LQPEVRFISATGEVNSEQIIT
>Mature_341_residues
MQNLQPFHTFHIQSNAREIIEAHSIEQLQQVWANSKSENLPTLFLGQGSNVLFLDDFNGIVILNRLMGITHEQDANFHYL
HVNGGENWHKLVEWSINNGIYGLENLALIPGCAGSAPIQNIGAYGVEFKDVCDYVEVLNLNTNETFRLDTEQCEFGYRES
IFKHRYQQGYVITAVGLKLKKDWQPILKYGSLVEFDPKTVTAKQIFDEVCHIRQSKLPDPNEVGNAGSFFKNPVVSSEHF
EEIKKHHENLPHFPQADGSVKLAAGWLIDQCNLKGFQIGGAAVHKKQALVLINKNGATGQDVVKLAHHVRQTVAEKFGVY
LQPEVRFISATGEVNSEQIIT

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=339, Percent_Identity=58.1120943952802, Blast_Score=424, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 38345; Mature: 38345

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNLQPFHTFHIQSNAREIIEAHSIEQLQQVWANSKSENLPTLFLGQGSNVLFLDDFNGI
CCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEECCCCE
VILNRLMGITHEQDANFHYLHVNGGENWHKLVEWSINNGIYGLENLALIPGCAGSAPIQN
EHHHHHHCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCEECCCCEEEECCCCCCCCHHH
IGAYGVEFKDVCDYVEVLNLNTNETFRLDTEQCEFGYRESIFKHRYQQGYVITAVGLKLK
CCCCCCCHHHHHHHHHHHCCCCCCEEEECHHHHCCCHHHHHHHHHHHCCEEEEEECCEEC
KDWQPILKYGSLVEFDPKTVTAKQIFDEVCHIRQSKLPDPNEVGNAGSFFKNPVVSSEHF
CCHHHHHHCCCEEEECCCCEEHHHHHHHHHHHHHHCCCCCHHCCCCCCHHCCCCCCHHHH
EEIKKHHENLPHFPQADGSVKLAAGWLIDQCNLKGFQIGGAAVHKKQALVLINKNGATGQ
HHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCEEEECCHHEECCEEEEEEECCCCCHH
DVVKLAHHVRQTVAEKFGVYLQPEVRFISATGEVNSEQIIT
HHHHHHHHHHHHHHHHCCCEECCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MQNLQPFHTFHIQSNAREIIEAHSIEQLQQVWANSKSENLPTLFLGQGSNVLFLDDFNGI
CCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEECCCCE
VILNRLMGITHEQDANFHYLHVNGGENWHKLVEWSINNGIYGLENLALIPGCAGSAPIQN
EHHHHHHCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCEECCCCEEEECCCCCCCCHHH
IGAYGVEFKDVCDYVEVLNLNTNETFRLDTEQCEFGYRESIFKHRYQQGYVITAVGLKLK
CCCCCCCHHHHHHHHHHHCCCCCCEEEECHHHHCCCHHHHHHHHHHHCCEEEEEECCEEC
KDWQPILKYGSLVEFDPKTVTAKQIFDEVCHIRQSKLPDPNEVGNAGSFFKNPVVSSEHF
CCHHHHHHCCCEEEECCCCEEHHHHHHHHHHHHHHCCCCCHHCCCCCCHHCCCCCCHHHH
EEIKKHHENLPHFPQADGSVKLAAGWLIDQCNLKGFQIGGAAVHKKQALVLINKNGATGQ
HHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCEEEECCHHEECCEEEEEEECCCCCHH
DVVKLAHHVRQTVAEKFGVYLQPEVRFISATGEVNSEQIIT
HHHHHHHHHHHHHHHHCCCEECCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA