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The map label for this gene is narQ

Identifier: 16272225

GI number: 16272225

Start: 300127

End: 301830

Strand: Direct

Name: narQ

Synonym: HI0267

Alternate gene names: 16272225

Gene position: 300127-301830 (Clockwise)

Preceding gene: 16272224

Following gene: 16272226

Centisome position: 16.4

GC content: 37.62

Gene sequence:

>1704_bases
GTGTATACTAAAGGTTCCGTTTCCACTCGTATTGCGAAATATTTATTTATCATTCTTATCGTTGCTGGTGTGATTAGTTC
TCTCAGTTTGGCAATTATGAGCAGTAATAAATATGATGCCGAAGCCATTAATATTTCAGGTTCTTTGCGTATGCAAAGTT
ATCGCTTACTTTATGAAATGCAAGAACAACCAGAAAGCGTGGAAACGAACTTACGCCGTTATCATATAAGCCTTCATTCA
TCTGCTTTACTAGAAGTTCAAAATCAATTTTTCACACCGAATGTATTAAAACATTCCTATCAAAACATTTTGCAACGTTG
GACGAACATGGAAAAATATGCGCGCCAACAGGATGTAAAAAACTATAGTAAGCAGCTTACTGACTATGTGGCAGATGTTG
ATTATTTTGTGTTTGAATTACAACGTTTTAGCGAGCAGAAATGGATTTTAGGCGTTTCAGTATTAGGTTTTGCGATGTTG
TTAATTTTGCTGATGGTGTCTTATGTGATTTGGTATACAAACCGAGAAGTTGTGAAACCTTTGCATTTAATGACAAAAGC
CAGTATGCAAGTGCAAATGCGTCAATTCAATCATATTCCACTTGACACAAGGAAACAAAATGAACTTGGCACACTGGCTC
GCGTATTTACACAAATGTCCACAGAACTGGGACAGCTTTATTCGCGTTTAGAAGAAGCGGTAAACGAAAAAACGCAAAAG
TTGCGTCAAACTAACCGCACTTTAAGCACTCTTTATCAAAGTGCTCAACTTCTGAATACAAACACAATTAACGATAAAAT
TTTAAATCAAGTTTTAAATTACATTTTTATTAGCGACCATTTGAACTTCGTTAAAGTGGAAGTGATGGGGGCTGAACATT
GGGATATTACATTGGGTAAGCAAGATGCTAATAATGAACTACAAATCGAAACCCTTTCTGTGGATAACGAAGAATTAGGT
GTACTCTCTTGGCAAGCAGGATTACCTTGTCCAGATCCCCGAATTATGCAAAATTTAGCGCAAATGCTTGCTCGTGCGCT
TTATTTCCATAAAAATTTACGTCAGAAAGAACAGCTTTTATTAATGGAAGAACGCTCAATTATTGCGCGAGAGTTGCACG
ATTCTTTGGCTCAAGTCTTATCATTTTTACAAATTCAACTTACTTTGCTCAAACATAATCTGAAGAAAGAAGACGAACAA
TCAAAAGAAAAGAGTTTGGCAATTATTGCCAATTTTGAACAAGCCCTTTCTGGTGGTTATGCACAGTTACGTGAGCTTTT
AGCCACTTTCCGTTTAACCATACAAGAAGCGAATTTACAGCTTGCACTAAAACAAGTGATTGATTCATTACGCTCGCAAA
CAACAATGCAAATGAATGTGAATTGTCAATTACCATCGCAAAGTTTGAACCCTCAACAGCTGGTTCACGTTCTGCAAATT
GTACGTGAAGCCACCACCAATGCGATCAAGCATTCTCAAGGCACGGTAATTGAAATTAGCGCAAGAATTAATGCGGAAGG
CGAGTATGAAATTTTAGTTGAAGATGATGGGGTTGGCATTCCAAACCTTGAAGAACCTGAAGGGCATTACGGCTTGAATA
TTATGGCGGAACGTTGTCGTCAGCTTAATGCACAATTGCATATTCATCGCCGTGAACAAGGCGGCACACAAGTCAAAATT
ACCTTGCCACATACATTATATTAG

Upstream 100 bases:

>100_bases
TTCAACGCTTATGGCGTGGTCAAGAAGATAAAGTTTGGGCTAAATTTAAAAAGAAATAAAAATTTTACCGCACTTTTCTA
AATTTCCACTGGAGTTTCCT

Downstream 100 bases:

>100_bases
GACATCAAAATGCAAAATTTACAACCTTTTCACACTTTCCACATTCAGTCTAATGCTCGTGAAATTATTGAAGCACATAG
TATCGAACAGCTACAACAAG

Product: nitrate/nitrite sensor protein NarQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 567; Mature: 567

Protein sequence:

>567_residues
MYTKGSVSTRIAKYLFIILIVAGVISSLSLAIMSSNKYDAEAINISGSLRMQSYRLLYEMQEQPESVETNLRRYHISLHS
SALLEVQNQFFTPNVLKHSYQNILQRWTNMEKYARQQDVKNYSKQLTDYVADVDYFVFELQRFSEQKWILGVSVLGFAML
LILLMVSYVIWYTNREVVKPLHLMTKASMQVQMRQFNHIPLDTRKQNELGTLARVFTQMSTELGQLYSRLEEAVNEKTQK
LRQTNRTLSTLYQSAQLLNTNTINDKILNQVLNYIFISDHLNFVKVEVMGAEHWDITLGKQDANNELQIETLSVDNEELG
VLSWQAGLPCPDPRIMQNLAQMLARALYFHKNLRQKEQLLLMEERSIIARELHDSLAQVLSFLQIQLTLLKHNLKKEDEQ
SKEKSLAIIANFEQALSGGYAQLRELLATFRLTIQEANLQLALKQVIDSLRSQTTMQMNVNCQLPSQSLNPQQLVHVLQI
VREATTNAIKHSQGTVIEISARINAEGEYEILVEDDGVGIPNLEEPEGHYGLNIMAERCRQLNAQLHIHRREQGGTQVKI
TLPHTLY

Sequences:

>Translated_567_residues
MYTKGSVSTRIAKYLFIILIVAGVISSLSLAIMSSNKYDAEAINISGSLRMQSYRLLYEMQEQPESVETNLRRYHISLHS
SALLEVQNQFFTPNVLKHSYQNILQRWTNMEKYARQQDVKNYSKQLTDYVADVDYFVFELQRFSEQKWILGVSVLGFAML
LILLMVSYVIWYTNREVVKPLHLMTKASMQVQMRQFNHIPLDTRKQNELGTLARVFTQMSTELGQLYSRLEEAVNEKTQK
LRQTNRTLSTLYQSAQLLNTNTINDKILNQVLNYIFISDHLNFVKVEVMGAEHWDITLGKQDANNELQIETLSVDNEELG
VLSWQAGLPCPDPRIMQNLAQMLARALYFHKNLRQKEQLLLMEERSIIARELHDSLAQVLSFLQIQLTLLKHNLKKEDEQ
SKEKSLAIIANFEQALSGGYAQLRELLATFRLTIQEANLQLALKQVIDSLRSQTTMQMNVNCQLPSQSLNPQQLVHVLQI
VREATTNAIKHSQGTVIEISARINAEGEYEILVEDDGVGIPNLEEPEGHYGLNIMAERCRQLNAQLHIHRREQGGTQVKI
TLPHTLY
>Mature_567_residues
MYTKGSVSTRIAKYLFIILIVAGVISSLSLAIMSSNKYDAEAINISGSLRMQSYRLLYEMQEQPESVETNLRRYHISLHS
SALLEVQNQFFTPNVLKHSYQNILQRWTNMEKYARQQDVKNYSKQLTDYVADVDYFVFELQRFSEQKWILGVSVLGFAML
LILLMVSYVIWYTNREVVKPLHLMTKASMQVQMRQFNHIPLDTRKQNELGTLARVFTQMSTELGQLYSRLEEAVNEKTQK
LRQTNRTLSTLYQSAQLLNTNTINDKILNQVLNYIFISDHLNFVKVEVMGAEHWDITLGKQDANNELQIETLSVDNEELG
VLSWQAGLPCPDPRIMQNLAQMLARALYFHKNLRQKEQLLLMEERSIIARELHDSLAQVLSFLQIQLTLLKHNLKKEDEQ
SKEKSLAIIANFEQALSGGYAQLRELLATFRLTIQEANLQLALKQVIDSLRSQTTMQMNVNCQLPSQSLNPQQLVHVLQI
VREATTNAIKHSQGTVIEISARINAEGEYEILVEDDGVGIPNLEEPEGHYGLNIMAERCRQLNAQLHIHRREQGGTQVKI
TLPHTLY

Specific function: Probable member of a two-component regulatory system. It is not known what protein it phosphorylates and in which regulatory pathway it acts, as the narL and other nar genes do not exist in H.influenzae

COG id: COG3850

COG function: function code T; Signal transduction histidine kinase, nitrate/nitrite-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain

Homologues:

Organism=Escherichia coli, GI1788812, Length=562, Percent_Identity=38.2562277580071, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI1787474, Length=579, Percent_Identity=28.3246977547496, Blast_Score=199, Evalue=5e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NARQ_HAEIN (P44604)

Other databases:

- EMBL:   L42023
- PIR:   F64058
- RefSeq:   NP_438436.1
- ProteinModelPortal:   P44604
- GeneID:   949389
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0267
- NMPDR:   fig|71421.1.peg.252
- TIGR:   HI_0267
- HOGENOM:   HBG758462
- OMA:   CYEDVRE
- ProtClustDB:   PRK10935
- BioCyc:   HINF71421:HI_0267-MONOMER
- BRENDA:   2.7.13.3
- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR016380
- InterPro:   IPR011712
- InterPro:   IPR005467
- Gene3D:   G3DSA:3.30.565.10
- PIRSF:   PIRSF003167
- SMART:   SM00304
- SMART:   SM00387

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF07730 HisKA_3; SSF55874 ATP_bd_ATPase

EC number: =2.7.13.3

Molecular weight: Translated: 65239; Mature: 65239

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50885 HAMP; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb5df994)-; HASH(0xc39399c)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTKGSVSTRIAKYLFIILIVAGVISSLSLAIMSSNKYDAEAINISGSLRMQSYRLLYEM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEECCCCHHHHHHHHHHHH
QEQPESVETNLRRYHISLHSSALLEVQNQFFTPNVLKHSYQNILQRWTNMEKYARQQDVK
HHCCCHHHHHHHHEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NYSKQLTDYVADVDYFVFELQRFSEQKWILGVSVLGFAMLLILLMVSYVIWYTNREVVKP
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LHLMTKASMQVQMRQFNHIPLDTRKQNELGTLARVFTQMSTELGQLYSRLEEAVNEKTQK
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRQTNRTLSTLYQSAQLLNTNTINDKILNQVLNYIFISDHLNFVKVEVMGAEHWDITLGK
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECC
QDANNELQIETLSVDNEELGVLSWQAGLPCPDPRIMQNLAQMLARALYFHKNLRQKEQLL
CCCCCCEEEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMEERSIIARELHDSLAQVLSFLQIQLTLLKHNLKKEDEQSKEKSLAIIANFEQALSGGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCEEEEECHHHHHCCCH
AQLRELLATFRLTIQEANLQLALKQVIDSLRSQTTMQMNVNCQLPSQSLNPQQLVHVLQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHH
VREATTNAIKHSQGTVIEISARINAEGEYEILVEDDGVGIPNLEEPEGHYGLNIMAERCR
HHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
QLNAQLHIHRREQGGTQVKITLPHTLY
HCCCCEEEEEECCCCCEEEEECCCCCH
>Mature Secondary Structure
MYTKGSVSTRIAKYLFIILIVAGVISSLSLAIMSSNKYDAEAINISGSLRMQSYRLLYEM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEECCCCHHHHHHHHHHHH
QEQPESVETNLRRYHISLHSSALLEVQNQFFTPNVLKHSYQNILQRWTNMEKYARQQDVK
HHCCCHHHHHHHHEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NYSKQLTDYVADVDYFVFELQRFSEQKWILGVSVLGFAMLLILLMVSYVIWYTNREVVKP
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LHLMTKASMQVQMRQFNHIPLDTRKQNELGTLARVFTQMSTELGQLYSRLEEAVNEKTQK
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRQTNRTLSTLYQSAQLLNTNTINDKILNQVLNYIFISDHLNFVKVEVMGAEHWDITLGK
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECC
QDANNELQIETLSVDNEELGVLSWQAGLPCPDPRIMQNLAQMLARALYFHKNLRQKEQLL
CCCCCCEEEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMEERSIIARELHDSLAQVLSFLQIQLTLLKHNLKKEDEQSKEKSLAIIANFEQALSGGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCEEEEECHHHHHCCCH
AQLRELLATFRLTIQEANLQLALKQVIDSLRSQTTMQMNVNCQLPSQSLNPQQLVHVLQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHH
VREATTNAIKHSQGTVIEISARINAEGEYEILVEDDGVGIPNLEEPEGHYGLNIMAERCR
HHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
QLNAQLHIHRREQGGTQVKITLPHTLY
HCCCCEEEEEECCCCCEEEEECCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800