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The map label for this gene is potC [H]

Identifier: 162448124

GI number: 162448124

Start: 1343155

End: 1344018

Strand: Direct

Name: potC [H]

Synonym: ACL_1285

Alternate gene names: 162448124

Gene position: 1343155-1344018 (Clockwise)

Preceding gene: 162448123

Following gene: 162448125

Centisome position: 89.72

GC content: 31.71

Gene sequence:

>864_bases
ATGACGCACTATCCAAAAGCAACCCTTGAATCCTACGGATACAAGGATTATAAGAAAACTAAAAAGTTTTTTACAGTTTT
AAGAAAAGTATTTGTTGTAGTGATTGTTGTATCTTTATATATACCCATTTTAATGTTACTACTTCAATCTGTAAACAGTA
GCCCAAACATCAATGAATTTGGTCACTTCACATTAGACTGGTATACAAATATGTTTGATGTAAGAAGTTTAAAGAATGCA
ATTATTAATACCTTATTAACCAGTGTGATATCCACACTGCTTGCAACAGTGATTGCAACCTTTATGGCAGTAGGTATTTA
TGCACTACCTAAACAAATACGTCAACGTGTTATGTTATTAAATAACATTCCAATATTAAATGCGGATATTGTTACAGGTA
TATCACTGATGCTTATCTTCTCACTATTATTACCACTATTTCCTTATATTTTTGGTCCAGTAACACTCATCATGGCCCAT
TTATTCTTCACGATTCCTTATGTCGTATTAAGTATCTTACCAAAGCTAAAAGAAATGGATACTAACCTTATGGATGCTGC
ACTAGATTTAGGGATTAAACCTTACAAAGCATTAATTAAAGTGATCGTACCAGCAATTAGTGCCGGAATATTTTCAGGTA
TGTTACTTGCTCTTACTATGAGTATTGATGACTTTGTTATTAGTTACTATACAACCGGCAATGGCTTTGATAACCTATCT
ATTTGGATTTACGGTAGTATCGGACGTAAGAGCTTAACACCTTCTGTATATGCCTTTTCTACATTGCTTACATTAATGAC
TTTATTAAGTCTTACACTCTATCAAGTGTTTATTAAAAAAGATAAAAAAGGTAAAATAAAATGA

Upstream 100 bases:

>100_bases
ACTACAACTTAGGTTCCCTATTATCTATTATGGTCTTACTCATTATCTTCTTAGGTATCTTTGTCGTAGCTAAGGTTGAT
AAGGAAGGAGAGATGCTTCT

Downstream 100 bases:

>100_bases
AAAAGTTATATATATTACTTGCATCAGTACTTACCATTTTTATTCTAAATGGTTGTACGATAAACAATAAATTATTAATC
CTTAACTGGGGTGAATATAT

Product: ABC transporter permease

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MTHYPKATLESYGYKDYKKTKKFFTVLRKVFVVVIVVSLYIPILMLLLQSVNSSPNINEFGHFTLDWYTNMFDVRSLKNA
IINTLLTSVISTLLATVIATFMAVGIYALPKQIRQRVMLLNNIPILNADIVTGISLMLIFSLLLPLFPYIFGPVTLIMAH
LFFTIPYVVLSILPKLKEMDTNLMDAALDLGIKPYKALIKVIVPAISAGIFSGMLLALTMSIDDFVISYYTTGNGFDNLS
IWIYGSIGRKSLTPSVYAFSTLLTLMTLLSLTLYQVFIKKDKKGKIK

Sequences:

>Translated_287_residues
MTHYPKATLESYGYKDYKKTKKFFTVLRKVFVVVIVVSLYIPILMLLLQSVNSSPNINEFGHFTLDWYTNMFDVRSLKNA
IINTLLTSVISTLLATVIATFMAVGIYALPKQIRQRVMLLNNIPILNADIVTGISLMLIFSLLLPLFPYIFGPVTLIMAH
LFFTIPYVVLSILPKLKEMDTNLMDAALDLGIKPYKALIKVIVPAISAGIFSGMLLALTMSIDDFVISYYTTGNGFDNLS
IWIYGSIGRKSLTPSVYAFSTLLTLMTLLSLTLYQVFIKKDKKGKIK
>Mature_286_residues
THYPKATLESYGYKDYKKTKKFFTVLRKVFVVVIVVSLYIPILMLLLQSVNSSPNINEFGHFTLDWYTNMFDVRSLKNAI
INTLLTSVISTLLATVIATFMAVGIYALPKQIRQRVMLLNNIPILNADIVTGISLMLIFSLLLPLFPYIFGPVTLIMAHL
FFTIPYVVLSILPKLKEMDTNLMDAALDLGIKPYKALIKVIVPAISAGIFSGMLLALTMSIDDFVISYYTTGNGFDNLSI
WIYGSIGRKSLTPSVYAFSTLLTLMTLLSLTLYQVFIKKDKKGKIK

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=261, Percent_Identity=32.5670498084291, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1787081, Length=249, Percent_Identity=28.5140562248996, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787714, Length=252, Percent_Identity=24.2063492063492, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32226; Mature: 32095

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
THYPKATLESYGYKDYKKTKKFFTVLRKVFVVVIVVSLYIPILMLLLQSVNSSPNINEF
CCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GHFTLDWYTNMFDVRSLKNAIINTLLTSVISTLLATVIATFMAVGIYALPKQIRQRVMLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NNIPILNADIVTGISLMLIFSLLLPLFPYIFGPVTLIMAHLFFTIPYVVLSILPKLKEMD
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TNLMDAALDLGIKPYKALIKVIVPAISAGIFSGMLLALTMSIDDFVISYYTTGNGFDNLS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEE
IWIYGSIGRKSLTPSVYAFSTLLTLMTLLSLTLYQVFIKKDKKGKIK
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]