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The map label for this gene is selR [H]

Identifier: 162447514

GI number: 162447514

Start: 680487

End: 680900

Strand: Direct

Name: selR [H]

Synonym: ACL_0654

Alternate gene names: 162447514

Gene position: 680487-680900 (Clockwise)

Preceding gene: 162447513

Following gene: 162447517

Centisome position: 45.46

GC content: 31.64

Gene sequence:

>414_bases
ATGAAAAAGTTAACGCCAATACAAAAAAAAGTAGCACTGGAAAATGGTACAGAACCACCATTTGATAATGCATACTGGAA
TAATTTTGATGAAGGTATTTATGTAGATGTCATGGACGGTACACCACTTTTTACATCACTTGATAAATTTGATGCAATGT
GTGGTTGGCCATCATTTACTAAACCAATTGATAATAAAATAGTGATTGAAAAAATAGATATGTCTTACGGTATGTTTAGA
ACGGAAGTAAGAACTAAAAATTCCAATATACATTTAGGTCATGTCTTTGATGATGGACCAGAAGATGAAGGTGGTCTAAG
ATATTGTATGAACTCAGCAAGTATGAGATTTATTCCTTTAGAAGACTTAGAAAAAGAAGGATATGGACAGTATAAATCAC
TGTTTGACAAATAA

Upstream 100 bases:

>100_bases
TACCGTATGGGAACACTAAGCTTTATCGCATTAACAGCAAGAAAGATATTGCCTGATAAATGGTTAGATTATATCTTATT
AAAAAGATAGGAGATATGAA

Downstream 100 bases:

>100_bases
TGAAATAAAAGGTGATGCATTTTATTAATGCATCACCTTTTCGTTACTTAGATTTATGAAATGGATTTGTACGTCCGTAT
AATTTAGTAAAACGTTTAAT

Product: methionine-R-sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MKKLTPIQKKVALENGTEPPFDNAYWNNFDEGIYVDVMDGTPLFTSLDKFDAMCGWPSFTKPIDNKIVIEKIDMSYGMFR
TEVRTKNSNIHLGHVFDDGPEDEGGLRYCMNSASMRFIPLEDLEKEGYGQYKSLFDK

Sequences:

>Translated_137_residues
MKKLTPIQKKVALENGTEPPFDNAYWNNFDEGIYVDVMDGTPLFTSLDKFDAMCGWPSFTKPIDNKIVIEKIDMSYGMFR
TEVRTKNSNIHLGHVFDDGPEDEGGLRYCMNSASMRFIPLEDLEKEGYGQYKSLFDK
>Mature_137_residues
MKKLTPIQKKVALENGTEPPFDNAYWNNFDEGIYVDVMDGTPLFTSLDKFDAMCGWPSFTKPIDNKIVIEKIDMSYGMFR
TEVRTKNSNIHLGHVFDDGPEDEGGLRYCMNSASMRFIPLEDLEKEGYGQYKSLFDK

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=121, Percent_Identity=47.1074380165289, Blast_Score=117, Evalue=3e-27,
Organism=Homo sapiens, GI301336162, Length=121, Percent_Identity=47.1074380165289, Blast_Score=117, Evalue=3e-27,
Organism=Homo sapiens, GI73089054, Length=121, Percent_Identity=47.1074380165289, Blast_Score=117, Evalue=3e-27,
Organism=Homo sapiens, GI37620216, Length=121, Percent_Identity=47.1074380165289, Blast_Score=117, Evalue=3e-27,
Organism=Homo sapiens, GI117606353, Length=126, Percent_Identity=42.8571428571429, Blast_Score=103, Evalue=7e-23,
Organism=Escherichia coli, GI1788077, Length=124, Percent_Identity=44.3548387096774, Blast_Score=111, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17553450, Length=109, Percent_Identity=45.8715596330275, Blast_Score=108, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI115532676, Length=109, Percent_Identity=45.8715596330275, Blast_Score=108, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6319816, Length=122, Percent_Identity=34.4262295081967, Blast_Score=72, Evalue=3e-14,
Organism=Drosophila melanogaster, GI221378664, Length=118, Percent_Identity=44.0677966101695, Blast_Score=106, Evalue=5e-24,
Organism=Drosophila melanogaster, GI221378662, Length=125, Percent_Identity=40.8, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI45553335, Length=118, Percent_Identity=43.2203389830509, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21356369, Length=118, Percent_Identity=43.2203389830509, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24645799, Length=118, Percent_Identity=43.2203389830509, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24645804, Length=129, Percent_Identity=39.5348837209302, Blast_Score=99, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24645801, Length=129, Percent_Identity=39.5348837209302, Blast_Score=99, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15737; Mature: 15737

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLTPIQKKVALENGTEPPFDNAYWNNFDEGIYVDVMDGTPLFTSLDKFDAMCGWPSFT
CCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCC
KPIDNKIVIEKIDMSYGMFRTEVRTKNSNIHLGHVFDDGPEDEGGLRYCMNSASMRFIPL
CCCCCEEEEEEECCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHCCCCEEEEEH
EDLEKEGYGQYKSLFDK
HHHCCCCCCHHHHHHCC
>Mature Secondary Structure
MKKLTPIQKKVALENGTEPPFDNAYWNNFDEGIYVDVMDGTPLFTSLDKFDAMCGWPSFT
CCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCC
KPIDNKIVIEKIDMSYGMFRTEVRTKNSNIHLGHVFDDGPEDEGGLRYCMNSASMRFIPL
CCCCCEEEEEEECCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHCCCCEEEEEH
EDLEKEGYGQYKSLFDK
HHHCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]