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The map label for this gene is mraY

Identifier: 162148958

GI number: 162148958

Start: 3275272

End: 3276363

Strand: Direct

Name: mraY

Synonym: GDI_3188

Alternate gene names: 162148958

Gene position: 3275272-3276363 (Clockwise)

Preceding gene: 162148957

Following gene: 162148959

Centisome position: 83.04

GC content: 66.48

Gene sequence:

>1092_bases
ATGCTCTACGACCTGATCCAGCATCACGGGTCGGCACACGTCACCGTCCTGAACCTGTTCCGCTACATCACCTTCCGCGC
CGGGGCGGCGTGCCTCACGGCGCTGGCGATCTCGCTGCTGCTGGGCAACCCGCTGATCGCGCAACTGCGCCGCATCCAGC
GCGAGGGTCAGCCGATCCGCGCCCTGGGCCCGGAACGCCACATCCTGGAAAAGGCCGGCACTCCCACCATGGGCGGCGTG
CTGATCCTGGCGGCCCTGTTCGGTTCAACGCTGCTGTGGGCGGACCTGACCGACGGGTATGTCTGGGCCGTGCTGCTGAC
CACGCTGAGCTTCGGCGCGGTGGGGTTCGCCGACGATTACCTGAAGCTGTCGCGGCGCAACACCGCCGGCGTGTCCAAGC
GCATGCGCCTGGGCTGCGAATTCGCGGCGTCGCTGGTCGGCGGCTACTGGATGCAGAGCCTGATGCCGGCGGACCTGGCC
AATCACCTGGCCTTTCCGTTCCTCAAGGAATGGCTGCTGCCGCTGGGCTTCGCCTTCCCGCTGTTTGCCATGATCACGAT
CACCGGCTTCGGCAACGCCGTCAATTTCACCGACGGGCTGGACGGGCTGGCGATCGTGCCGGTCATCATCGCGGCGCTGG
TCTTCGGGCTGATCTCGTATCTGGTCGGCAACCACGTCTTCGCCGACTACCTGCAACTGCACGCGGTGCCGGGCACGGGC
GAGCTGTGCGTATTCTGTTCGGCCCTGGTCGGCGCGGGGCTGGGCTTCCTGTGGTTCAACGCCCCGCCGGCGGCGGTGTT
CATGGGCGATACCGGGTCGCTGTCGCTGGGCGGCGCGCTGGGCGCGATCGCCGTCGCGGTGAAGCATGAACTGGTGCTGT
GCATCGTCGGCGGCCTGTTCGTGGTCGAAACCCTGTCCGTGATCATCCAGGTCTTCTGGTTCCGCCGCACCGGGCGGCGG
GTGTTCCTGATGGCGCCGCTGCACCATCATTTCGAAAAGAAAGGCTGGCAGGAGCCCAAGATCGTCATCCGCTTCTGGAT
CGTGTCCATCGTCCTGGGACTGTGTGGCCTGGCCACGCTGAAGCTGCGATGA

Upstream 100 bases:

>100_bases
ACGTGATCCTGGTCAAGGGCAGCTTCGGCAGCCGCATGCGCGATGTCGTCTCGGTGCTGACCGCGCCCGCGACGGCACCC
TCCAAGGCGGGTGCGGCCTG

Downstream 100 bases:

>100_bases
GCGGCCCGGGCCTGTTCCCCCCCGGCCTGTTGGCCGGCAGCCGCTACGCGGTGCTGGGGCTGGGGCGCAACGGCGCCCCC
GCCGTCCGCGCGCTGGCCGC

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MLYDLIQHHGSAHVTVLNLFRYITFRAGAACLTALAISLLLGNPLIAQLRRIQREGQPIRALGPERHILEKAGTPTMGGV
LILAALFGSTLLWADLTDGYVWAVLLTTLSFGAVGFADDYLKLSRRNTAGVSKRMRLGCEFAASLVGGYWMQSLMPADLA
NHLAFPFLKEWLLPLGFAFPLFAMITITGFGNAVNFTDGLDGLAIVPVIIAALVFGLISYLVGNHVFADYLQLHAVPGTG
ELCVFCSALVGAGLGFLWFNAPPAAVFMGDTGSLSLGGALGAIAVAVKHELVLCIVGGLFVVETLSVIIQVFWFRRTGRR
VFLMAPLHHHFEKKGWQEPKIVIRFWIVSIVLGLCGLATLKLR

Sequences:

>Translated_363_residues
MLYDLIQHHGSAHVTVLNLFRYITFRAGAACLTALAISLLLGNPLIAQLRRIQREGQPIRALGPERHILEKAGTPTMGGV
LILAALFGSTLLWADLTDGYVWAVLLTTLSFGAVGFADDYLKLSRRNTAGVSKRMRLGCEFAASLVGGYWMQSLMPADLA
NHLAFPFLKEWLLPLGFAFPLFAMITITGFGNAVNFTDGLDGLAIVPVIIAALVFGLISYLVGNHVFADYLQLHAVPGTG
ELCVFCSALVGAGLGFLWFNAPPAAVFMGDTGSLSLGGALGAIAVAVKHELVLCIVGGLFVVETLSVIIQVFWFRRTGRR
VFLMAPLHHHFEKKGWQEPKIVIRFWIVSIVLGLCGLATLKLR
>Mature_363_residues
MLYDLIQHHGSAHVTVLNLFRYITFRAGAACLTALAISLLLGNPLIAQLRRIQREGQPIRALGPERHILEKAGTPTMGGV
LILAALFGSTLLWADLTDGYVWAVLLTTLSFGAVGFADDYLKLSRRNTAGVSKRMRLGCEFAASLVGGYWMQSLMPADLA
NHLAFPFLKEWLLPLGFAFPLFAMITITGFGNAVNFTDGLDGLAIVPVIIAALVFGLISYLVGNHVFADYLQLHAVPGTG
ELCVFCSALVGAGLGFLWFNAPPAAVFMGDTGSLSLGGALGAIAVAVKHELVLCIVGGLFVVETLSVIIQVFWFRRTGRR
VFLMAPLHHHFEKKGWQEPKIVIRFWIVSIVLGLCGLATLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=366, Percent_Identity=49.1803278688525, Blast_Score=322, Evalue=2e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_GLUDA (A9H0I1)

Other databases:

- EMBL:   AM889285
- EMBL:   CP001189
- RefSeq:   YP_001603419.1
- RefSeq:   YP_002277518.1
- GeneID:   5790605
- GeneID:   6976611
- GenomeReviews:   AM889285_GR
- GenomeReviews:   CP001189_GR
- KEGG:   gdj:Gdia_3173
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 39302; Mature: 39302

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x17889254)-; HASH(0x1788413c)-; HASH(0x177454dc)-; HASH(0x167ec5e8)-; HASH(0x17934148)-; HASH(0x406cc78c)-; HASH(0x178d5154)-; HASH(0x17400388)-; HASH(0x406ac080)-; HASH(0x17c344b0)-;

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYDLIQHHGSAHVTVLNLFRYITFRAGAACLTALAISLLLGNPLIAQLRRIQREGQPIR
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
ALGPERHILEKAGTPTMGGVLILAALFGSTLLWADLTDGYVWAVLLTTLSFGAVGFADDY
CCCCHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHH
LKLSRRNTAGVSKRMRLGCEFAASLVGGYWMQSLMPADLANHLAFPFLKEWLLPLGFAFP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
LFAMITITGFGNAVNFTDGLDGLAIVPVIIAALVFGLISYLVGNHVFADYLQLHAVPGTG
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCC
ELCVFCSALVGAGLGFLWFNAPPAAVFMGDTGSLSLGGALGAIAVAVKHELVLCIVGGLF
HHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VVETLSVIIQVFWFRRTGRRVFLMAPLHHHFEKKGWQEPKIVIRFWIVSIVLGLCGLATL
HHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
KLR
CCH
>Mature Secondary Structure
MLYDLIQHHGSAHVTVLNLFRYITFRAGAACLTALAISLLLGNPLIAQLRRIQREGQPIR
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
ALGPERHILEKAGTPTMGGVLILAALFGSTLLWADLTDGYVWAVLLTTLSFGAVGFADDY
CCCCHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHH
LKLSRRNTAGVSKRMRLGCEFAASLVGGYWMQSLMPADLANHLAFPFLKEWLLPLGFAFP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
LFAMITITGFGNAVNFTDGLDGLAIVPVIIAALVFGLISYLVGNHVFADYLQLHAVPGTG
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCC
ELCVFCSALVGAGLGFLWFNAPPAAVFMGDTGSLSLGGALGAIAVAVKHELVLCIVGGLF
HHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VVETLSVIIQVFWFRRTGRRVFLMAPLHHHFEKKGWQEPKIVIRFWIVSIVLGLCGLATL
HHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
KLR
CCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA