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The map label for this gene is ygjG [C]

Identifier: 162147790

GI number: 162147790

Start: 2044451

End: 2045764

Strand: Direct

Name: ygjG [C]

Synonym: GDI_2006

Alternate gene names: 162147790

Gene position: 2044451-2045764 (Clockwise)

Preceding gene: 162147789

Following gene: 162147791

Centisome position: 51.83

GC content: 68.26

Gene sequence:

>1314_bases
ATGCCGCCGACCAATCACGACGCGTTCTGGATGCCGTTCACCGCCAACCGCCAGTTCCGCAAGACGCCGCGCATGCTGGT
GGCGGCCGACGGCATGTATTACACCACCGACGACGGGCGAAAGGTGCTGGATGGCTGCGCCGGCCTGTGGTGCGTGAACG
CGGGCCATAACCGCCCGCGCATCACCCAGGCGGTGCAGAAGACGATCGCGACGCTGGATTTCGCGCCGACCTTCCAGATG
GGCCACCCGCTGGCCTTCGAGGCCGCGGACCGGATCGCGGCCCTGGCGCCCGGCGACCTGAACCATGTCTTCTTCTGCAA
TTCGGGCTCCGAGGCCATGGATTCGGCGCTGAAGATCGCCCTCGCCTATCACCGCGTGCGGGGCGAGGGCGCGCGCACGC
GCCTGATCGGGCGCGAGCGCGGATATCACGGCGTGGGGTTCGGCGGCATTTCCGTGGGCGGCCTGTCCGGCAACCGCAAG
CTGTACGGGTCGCTGCTGACCGGGGTCGACCACCTGCCGCACACGCTGGATATCGAACGGAACGCGTTCACCAGGGGGCT
GCCCGCCCACGGCGCGGAACTGGCGGACAACCTGGAACGCATCGTCGCGCTGCATGACGCATCCACCATCGCCGCCGTGG
TGGTCGAACCGATGGCCGGATCGACCGGCGTGCTGCCGCCGCCGGTCGGCTACCTGAAGCGCCTGCGCGAGATCTGCGAC
AAATACGGCATCCTGCTGATCTTCGACGAGGTCATCACCGGGTTCGGCCGCCTGGGCGGCACTCCCTTCGCGGCCGAGAA
ATTCGGCGTGCTGCCCGATATCCTGGCCTGCGCCAAGGGCGTGACCAACGGGACCATCCCCATGGGCGCCGCCATCGCGC
GCGACCATGTGCACGCGGCGTTCATGACCGGGCCGGAAACCGGGATCGAACTGCCGCACGGCTATACCTATTCGGGCCAC
CCCGTGGCCTGCGCCGCCGCGATCGCGACCCTGGACACCTACGCCGAGGAGAACCTGTTCGAGCGCGCGGGCGACATCGC
GCCCTATTTCGAGGAAGCGGTCCACGCGTTGCGCGGCCTGCCGCATGTCATCGACATCCGCAATGTGGGGCTGGTGGCCG
GCATCGAACTGGCGTCCCGTCCCGGCGCGGTGGGCGCCAGGGCGTACGAGGTCTTCGACCGCGCGTTCCACAAGGGAATC
CTGGTCCGCTACACCGGCGACGTGGTCGCCGTCTCGCCGCCGCTGATCATCGAAAAATCGCAGATCGACCAGGTGTTCGG
CACCCTGGCCGACATCATCCACGCCGTCGAATAG

Upstream 100 bases:

>100_bases
GTTCCATCCTCGTGACGATTTCGGAACCGTGACAGGGTTCTCTGTGCCAGGTTCTCTGTGCCAAGCGGTTCCCCATCATC
GATCGCAGGAGCTTCGCGCG

Downstream 100 bases:

>100_bases
CGCGGAACGCGAGGCCCGAATGACAGACACCCCGCCCCCTGCGACGGCCGCCGGCTACGATCCCGGCCTGTATAACGCGG
ACCTGGCCCCGGTTCCGGCC

Product: beta alanine--pyruvate transaminase

Products: NA

Alternate protein names: Omega-APT; Beta-alanine--pyruvate aminotransferase [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MPPTNHDAFWMPFTANRQFRKTPRMLVAADGMYYTTDDGRKVLDGCAGLWCVNAGHNRPRITQAVQKTIATLDFAPTFQM
GHPLAFEAADRIAALAPGDLNHVFFCNSGSEAMDSALKIALAYHRVRGEGARTRLIGRERGYHGVGFGGISVGGLSGNRK
LYGSLLTGVDHLPHTLDIERNAFTRGLPAHGAELADNLERIVALHDASTIAAVVVEPMAGSTGVLPPPVGYLKRLREICD
KYGILLIFDEVITGFGRLGGTPFAAEKFGVLPDILACAKGVTNGTIPMGAAIARDHVHAAFMTGPETGIELPHGYTYSGH
PVACAAAIATLDTYAEENLFERAGDIAPYFEEAVHALRGLPHVIDIRNVGLVAGIELASRPGAVGARAYEVFDRAFHKGI
LVRYTGDVVAVSPPLIIEKSQIDQVFGTLADIIHAVE

Sequences:

>Translated_437_residues
MPPTNHDAFWMPFTANRQFRKTPRMLVAADGMYYTTDDGRKVLDGCAGLWCVNAGHNRPRITQAVQKTIATLDFAPTFQM
GHPLAFEAADRIAALAPGDLNHVFFCNSGSEAMDSALKIALAYHRVRGEGARTRLIGRERGYHGVGFGGISVGGLSGNRK
LYGSLLTGVDHLPHTLDIERNAFTRGLPAHGAELADNLERIVALHDASTIAAVVVEPMAGSTGVLPPPVGYLKRLREICD
KYGILLIFDEVITGFGRLGGTPFAAEKFGVLPDILACAKGVTNGTIPMGAAIARDHVHAAFMTGPETGIELPHGYTYSGH
PVACAAAIATLDTYAEENLFERAGDIAPYFEEAVHALRGLPHVIDIRNVGLVAGIELASRPGAVGARAYEVFDRAFHKGI
LVRYTGDVVAVSPPLIIEKSQIDQVFGTLADIIHAVE
>Mature_436_residues
PPTNHDAFWMPFTANRQFRKTPRMLVAADGMYYTTDDGRKVLDGCAGLWCVNAGHNRPRITQAVQKTIATLDFAPTFQMG
HPLAFEAADRIAALAPGDLNHVFFCNSGSEAMDSALKIALAYHRVRGEGARTRLIGRERGYHGVGFGGISVGGLSGNRKL
YGSLLTGVDHLPHTLDIERNAFTRGLPAHGAELADNLERIVALHDASTIAAVVVEPMAGSTGVLPPPVGYLKRLREICDK
YGILLIFDEVITGFGRLGGTPFAAEKFGVLPDILACAKGVTNGTIPMGAAIARDHVHAAFMTGPETGIELPHGYTYSGHP
VACAAAIATLDTYAEENLFERAGDIAPYFEEAVHALRGLPHVIDIRNVGLVAGIELASRPGAVGARAYEVFDRAFHKGIL
VRYTGDVVAVSPPLIIEKSQIDQVFGTLADIIHAVE

Specific function: Catalyzes transamination between a variety of omega- amino acids, mono and diamines, and pyruvate. Plays a pivotal role in the metabolism of the omega amino acids [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=429, Percent_Identity=28.4382284382284, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI13994255, Length=430, Percent_Identity=28.1395348837209, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI37574042, Length=437, Percent_Identity=27.2311212814645, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI226442705, Length=434, Percent_Identity=26.9585253456221, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI226442709, Length=397, Percent_Identity=27.455919395466, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI284507298, Length=323, Percent_Identity=29.7213622291022, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI24119277, Length=436, Percent_Identity=26.3761467889908, Blast_Score=117, Evalue=3e-26,
Organism=Escherichia coli, GI145693181, Length=394, Percent_Identity=32.48730964467, Blast_Score=187, Evalue=9e-49,
Organism=Escherichia coli, GI1786991, Length=409, Percent_Identity=31.7848410757946, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1789016, Length=405, Percent_Identity=30.8641975308642, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1789759, Length=422, Percent_Identity=29.3838862559242, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI1788044, Length=422, Percent_Identity=27.2511848341232, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1787560, Length=441, Percent_Identity=27.437641723356, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1786349, Length=394, Percent_Identity=31.2182741116751, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI32564660, Length=440, Percent_Identity=28.4090909090909, Blast_Score=151, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI25144271, Length=421, Percent_Identity=28.2660332541568, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71992977, Length=441, Percent_Identity=29.9319727891156, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI25144274, Length=241, Percent_Identity=33.6099585062241, Blast_Score=118, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6324386, Length=429, Percent_Identity=27.5058275058275, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6323470, Length=433, Percent_Identity=25.1732101616628, Blast_Score=134, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6324432, Length=417, Percent_Identity=26.8585131894484, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI161085790, Length=439, Percent_Identity=28.7015945330296, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI28574759, Length=445, Percent_Identity=29.2134831460674, Blast_Score=141, Evalue=9e-34,
Organism=Drosophila melanogaster, GI21357415, Length=416, Percent_Identity=26.2019230769231, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI21356575, Length=436, Percent_Identity=28.6697247706422, Blast_Score=129, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.18 [H]

Molecular weight: Translated: 46780; Mature: 46649

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPTNHDAFWMPFTANRQFRKTPRMLVAADGMYYTTDDGRKVLDGCAGLWCVNAGHNRPR
CCCCCCCCEEEEECCCCHHHCCCCEEEEECCEEEECCCCHHHHHHHCCEEEECCCCCCHH
ITQAVQKTIATLDFAPTFQMGHPLAFEAADRIAALAPGDLNHVFFCNSGSEAMDSALKIA
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHEEECCCCCCEEEEECCCCHHHHHHHHHH
LAYHRVRGEGARTRLIGRERGYHGVGFGGISVGGLSGNRKLYGSLLTGVDHLPHTLDIER
HHHHHHCCCCCCEEEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEECCC
NAFTRGLPAHGAELADNLERIVALHDASTIAAVVVEPMAGSTGVLPPPVGYLKRLREICD
CHHHCCCCCCCHHHHHHHHHHHHHHCCHHEEEHEEECCCCCCCCCCCCHHHHHHHHHHHH
KYGILLIFDEVITGFGRLGGTPFAAEKFGVLPDILACAKGVTNGTIPMGAAIARDHVHAA
HCCEEEEEHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHEE
FMTGPETGIELPHGYTYSGHPVACAAAIATLDTYAEENLFERAGDIAPYFEEAVHALRGL
EECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
PHVIDIRNVGLVAGIELASRPGAVGARAYEVFDRAFHKGILVRYTGDVVAVSPPLIIEKS
CCEEEECCCCEEECCHHCCCCCCCCHHHHHHHHHHHHCCEEEEEECCEEEECCCEEEEHH
QIDQVFGTLADIIHAVE
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PPTNHDAFWMPFTANRQFRKTPRMLVAADGMYYTTDDGRKVLDGCAGLWCVNAGHNRPR
CCCCCCCEEEEECCCCHHHCCCCEEEEECCEEEECCCCHHHHHHHCCEEEECCCCCCHH
ITQAVQKTIATLDFAPTFQMGHPLAFEAADRIAALAPGDLNHVFFCNSGSEAMDSALKIA
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHEEECCCCCCEEEEECCCCHHHHHHHHHH
LAYHRVRGEGARTRLIGRERGYHGVGFGGISVGGLSGNRKLYGSLLTGVDHLPHTLDIER
HHHHHHCCCCCCEEEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEECCC
NAFTRGLPAHGAELADNLERIVALHDASTIAAVVVEPMAGSTGVLPPPVGYLKRLREICD
CHHHCCCCCCCHHHHHHHHHHHHHHCCHHEEEHEEECCCCCCCCCCCCHHHHHHHHHHHH
KYGILLIFDEVITGFGRLGGTPFAAEKFGVLPDILACAKGVTNGTIPMGAAIARDHVHAA
HCCEEEEEHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHEE
FMTGPETGIELPHGYTYSGHPVACAAAIATLDTYAEENLFERAGDIAPYFEEAVHALRGL
EECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
PHVIDIRNVGLVAGIELASRPGAVGARAYEVFDRAFHKGILVRYTGDVVAVSPPLIIEKS
CCEEEECCCCEEECCHHCCCCCCCCHHHHHHHHHHHHCCEEEEEECCEEEECCCEEEEHH
QIDQVFGTLADIIHAVE
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1618757; 6822556; 2500426 [H]