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The map label for this gene is mtrA [H]

Identifier: 162147599

GI number: 162147599

Start: 1848883

End: 1849650

Strand: Direct

Name: mtrA [H]

Synonym: GDI_1815

Alternate gene names: 162147599

Gene position: 1848883-1849650 (Clockwise)

Preceding gene: 162147597

Following gene: 162147602

Centisome position: 46.88

GC content: 64.19

Gene sequence:

>768_bases
ATGGATACCGGCCCCACGCAGATGGGGAACGGTCAAAATAAAGAGGGTTCGATGGCAGGTGCGCGTCCCATTCTGATAGT
GGATGACGATCAGACGTTACGTCATATGCTCGTCGAACAATTGCAGTTGGAAGGAGAGTTCCAGGCGATCGAAGCCGACT
CGGTCGCCGATGCCTGGGACAAGCTGAATGCCCCGGGGGCGCGATTCGACGCCATCATCCTGGACGTGACGCTGCCCGAC
GGGGACGGACGGGATTTCTGCGCCGAGCTGCGGCGCCAGGGCAAGCGGATCCCCATCATCATCCTGACGGGTTCGGACGA
TGAAACGGACGTGGTACGCGGGCTGGATGCCGGGGCCAACGACTATGTCGCCAAGCCCTTCCGCATCGCCGAGCTGCTGG
CCCGGCTGCGCGCCCAGATGCGCATCTTCGAAAACAGCGAGGACGCGGTCTTCTCGATCGGGCCGTATGTGTTCCGTCCG
TCGGCCAAGCTGCTGCAGGAACCCACGCGCAACCGCCGCATCCGGCTGACCGAGAAAGAGGCGGCGATCCTGAAATTCCT
CTATCGCGCCGGGACGCGGCCGGTGCCGCGCCAGGTCCTGCTGAACGAGGTCTGGGGCTATAACGCCGCCGTCACCACCC
ACACGCTGGAAACCCACATCTACCGCCTGCGGCAGAAGATCGAGCCCGATCCGACCAACGCGTCGCTGCTGGTGACCGAG
GGCGGCGGCTATCGCCTGGACCCCGAGGGTGGAATGCGCATCGCCTGA

Upstream 100 bases:

>100_bases
CGGTCCTAGAGTGGACGATACCGGCGTAGTCGTGAAAGAGGTACCGTGCGGGGTGGCTGGCTCCGGACGCTGCCGTTTCC
GCGCCAGGATGATATAGGTT

Downstream 100 bases:

>100_bases
GTATTGGTCCGGAAACGCGCGCTGGTGGTGATCCGGCGCGCGTTTCCGGGATGCTCCGGTGCGCAGAAACACATGGCGGA
GGCGGGCCCTTTGGGACGCT

Product: DNA-binding response regulator mtrA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MDTGPTQMGNGQNKEGSMAGARPILIVDDDQTLRHMLVEQLQLEGEFQAIEADSVADAWDKLNAPGARFDAIILDVTLPD
GDGRDFCAELRRQGKRIPIIILTGSDDETDVVRGLDAGANDYVAKPFRIAELLARLRAQMRIFENSEDAVFSIGPYVFRP
SAKLLQEPTRNRRIRLTEKEAAILKFLYRAGTRPVPRQVLLNEVWGYNAAVTTHTLETHIYRLRQKIEPDPTNASLLVTE
GGGYRLDPEGGMRIA

Sequences:

>Translated_255_residues
MDTGPTQMGNGQNKEGSMAGARPILIVDDDQTLRHMLVEQLQLEGEFQAIEADSVADAWDKLNAPGARFDAIILDVTLPD
GDGRDFCAELRRQGKRIPIIILTGSDDETDVVRGLDAGANDYVAKPFRIAELLARLRAQMRIFENSEDAVFSIGPYVFRP
SAKLLQEPTRNRRIRLTEKEAAILKFLYRAGTRPVPRQVLLNEVWGYNAAVTTHTLETHIYRLRQKIEPDPTNASLLVTE
GGGYRLDPEGGMRIA
>Mature_255_residues
MDTGPTQMGNGQNKEGSMAGARPILIVDDDQTLRHMLVEQLQLEGEFQAIEADSVADAWDKLNAPGARFDAIILDVTLPD
GDGRDFCAELRRQGKRIPIIILTGSDDETDVVRGLDAGANDYVAKPFRIAELLARLRAQMRIFENSEDAVFSIGPYVFRP
SAKLLQEPTRNRRIRLTEKEAAILKFLYRAGTRPVPRQVLLNEVWGYNAAVTTHTLETHIYRLRQKIEPDPTNASLLVTE
GGGYRLDPEGGMRIA

Specific function: Member of the two-component regulatory system sphR/sphS. Response regulator. Involved in inducible production of alkaline phosphatase in response to phosphate limitation as it is directly involved in the regulation of phoA transcription in response to pho

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=36.7521367521368, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=35.8407079646018, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=33.9285714285714, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789809, Length=239, Percent_Identity=34.3096234309623, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=36.7713004484305, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1789402, Length=167, Percent_Identity=37.125748502994, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=33.9055793991416, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=32.1266968325792, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=33.1877729257642, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=30.5309734513274, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI2367329, Length=216, Percent_Identity=34.2592592592593, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=29.9145299145299, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787229, Length=189, Percent_Identity=30.1587301587302, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28400; Mature: 28400

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTGPTQMGNGQNKEGSMAGARPILIVDDDQTLRHMLVEQLQLEGEFQAIEADSVADAWD
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHH
KLNAPGARFDAIILDVTLPDGDGRDFCAELRRQGKRIPIIILTGSDDETDVVRGLDAGAN
HCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHCCCCCC
DYVAKPFRIAELLARLRAQMRIFENSEDAVFSIGPYVFRPSAKLLQEPTRNRRIRLTEKE
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEECCCHHHHHCCCCCCEEEEEHHH
AAILKFLYRAGTRPVPRQVLLNEVWGYNAAVTTHTLETHIYRLRQKIEPDPTNASLLVTE
HHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCEEEEEC
GGGYRLDPEGGMRIA
CCCEEECCCCCCCCC
>Mature Secondary Structure
MDTGPTQMGNGQNKEGSMAGARPILIVDDDQTLRHMLVEQLQLEGEFQAIEADSVADAWD
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHH
KLNAPGARFDAIILDVTLPDGDGRDFCAELRRQGKRIPIIILTGSDDETDVVRGLDAGAN
HCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHCCCCCC
DYVAKPFRIAELLARLRAQMRIFENSEDAVFSIGPYVFRPSAKLLQEPTRNRRIRLTEKE
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEECCCHHHHHCCCCCCEEEEEHHH
AAILKFLYRAGTRPVPRQVLLNEVWGYNAAVTTHTLETHIYRLRQKIEPDPTNASLLVTE
HHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCEEEEEC
GGGYRLDPEGGMRIA
CCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8497200; 8157591 [H]