Click here to switch to the map view.

The map label for this gene is cvrA [C]

Identifier: 162147597

GI number: 162147597

Start: 1846243

End: 1848066

Strand: Direct

Name: cvrA [C]

Synonym: GDI_1813

Alternate gene names: 162147597

Gene position: 1846243-1848066 (Clockwise)

Preceding gene: 162147596

Following gene: 162147599

Centisome position: 46.81

GC content: 68.48

Gene sequence:

>1824_bases
ATGCAGGATAATCTGGCCATCGGGATCTTATGCGTGCTGGGCGGCGGAATCGGCGCCCAATGGGTAGCGTGGCGATTCCG
GCTGCCGGCCATCGTCCTGCTGTTCGCGCTGGGGCTGCTGTACGGGCCGGGGCTGAACCTGCTGCATCCGTCGGCCGCGA
TCGGCGGCTATTTCCATCCCATCGTCTCGCTGGCCGTCGCCTTCATCGTGTTCGAAGGCGGGCTGGGGCTGGATTTCCGG
CAATGGCGCGCGGCGGGCGAGGGCGTGCTGCGCCTGACGGTCGTGGCCCTGCCGATCAACTGGATCCTGGGCGCGCTGGC
GGCGCATTTCGTCGGGCATCTGCACTGGGGCGCATCCTGGCTGTTCGGTGCCATCATCGTGGTGACGGGGCCGACGGTGG
TGCTGCCGCTGCTGCGCCACACCAAGCTGCGCCCCCGGGTGGCGGCCTTCCTGCGGTGGGAGGCCATCCTGAACGACCCG
GTGGGCGCGATCCTGGCGACGCTGGTGCTGGAATTCCTGATGATCCAGGGCAACCGGCATTCGGGCATGTTCATGGCCGA
AATCGTGCCCCACCTGCTGTTCGCCACCATGATGGCGCTGGGCTGCGGGGTGTTTCCGGCCGTGCTGGTGCGGTTTCTGT
CCACCCGCGACCTGATCCCGGAAATCCTGCGCATTCCCATCATCCTGACGCTGGCGATGAGCGTCTTCGCGGTCTGCAAC
TTCGTCATGGAAGGGGCGGGGCTGATGGCCGCCACGGTCTTCGGCATGGCGCTGACGAACATGCACGTCATCGGCATGTC
CGAACTGCGGCGGATCAAGGAATCGCTGGGCGTGCTGGTGGTGTCGTGCCTGTTCGTGATGCTGACCGCCGATCTGCATC
GCGCGGTGCTGGAACGCCTGTCGCTGCCGATCGTGGCGATGACGCTGACCGTGCTGTTCGTGGTGCGGCCGGTGGGTATC
CTGCTGTCCACCATCCGCGCCAACCTGTCGTGGCAGGAACGCCTGTTCGTCGGCTGGATCGCGCCGCGCGGGATCGTGGC
CGCCGCCGTCGCCGGCGTCGCCGGCCTGCAATTGCAGGAAGCCGGCTATCCCAGCGCCGACCTGGTGACGCCGGGCGTGT
TCGCCCTGATCGCCACCACCATGATCCTGCATGGGTTTTCGCTTCGCCCGCTGGCGCGCGCGCTGCGCCTGACCCTGTCC
GACGAACCGGCGCTGGCGATCGTCGGCGCCAGCGCCTGGTCCACCGACCTGGCCGGCGTGCTGCATCGCCTGGGGTGCCC
GGTCATGCTGGTGGACACCTGTACCGGCGCGCTGGCCCCCGCGTCACGCGCCGGCATCCCGATCCTGAAGGCGGAACTGC
TGTCCGACGAAGGGCTGGAAAGCCTGGAGGAACGGCCGGCGGACTATCTGATCGCGGCGACGCCGGACGCGATCTACAAC
GGACTGGTCTGCGCGCGGCTGGCGCCGGATTTCGGGCGCCAGCGCGTGTTCCAGGTCAGCCCCGGCGTGGCGCGGCTGGA
TCTGTACCGGGGGTTGAGCCGCGATTCACGGGGCAGGGTGCTGGGCGATCCGGCATGGAACTTCACGCTGTTCGATACCC
TGTTCGAACGGGGCTGGCGCTTTCGCAGCATCCCCTTCGTGCCGCCGCCGGCCGGCGGCGCGGCAGGCGGGACGCCGCCC
CCGGGCGAACCCCTTGCCGAAGGCAATCGCCTGACGATCATGACCGTGCGCAAGGGCGTCGCCATCTGGGTCCGGTCGGT
CGAGGACGAGGTACCGGTCGAGCCGATGGCCGGAGATACGATCATCATCATGTCGCCCCCGTGA

Upstream 100 bases:

>100_bases
TTTTTAATGACAAAGTGGTCGATCGTTCCGGATTGTCGCTGTCCCGGCCCGCGTTGTAATCTGACGGATATCAAGGCGGC
CCAACAGGTCGGGAGACGCA

Downstream 100 bases:

>100_bases
GTCTGTCTGGAAACGCGCGCTGGCGGCGATCCGACGCGCGTTTCCTGTGCTTCGCTGCTCACGGCCATCAAGGCCGCTCC
GCTGCGATGCTCGGAAACAC

Product: cell volume regulation protein A

Products: NA

Alternate protein names: MjNhaP2 [H]

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MQDNLAIGILCVLGGGIGAQWVAWRFRLPAIVLLFALGLLYGPGLNLLHPSAAIGGYFHPIVSLAVAFIVFEGGLGLDFR
QWRAAGEGVLRLTVVALPINWILGALAAHFVGHLHWGASWLFGAIIVVTGPTVVLPLLRHTKLRPRVAAFLRWEAILNDP
VGAILATLVLEFLMIQGNRHSGMFMAEIVPHLLFATMMALGCGVFPAVLVRFLSTRDLIPEILRIPIILTLAMSVFAVCN
FVMEGAGLMAATVFGMALTNMHVIGMSELRRIKESLGVLVVSCLFVMLTADLHRAVLERLSLPIVAMTLTVLFVVRPVGI
LLSTIRANLSWQERLFVGWIAPRGIVAAAVAGVAGLQLQEAGYPSADLVTPGVFALIATTMILHGFSLRPLARALRLTLS
DEPALAIVGASAWSTDLAGVLHRLGCPVMLVDTCTGALAPASRAGIPILKAELLSDEGLESLEERPADYLIAATPDAIYN
GLVCARLAPDFGRQRVFQVSPGVARLDLYRGLSRDSRGRVLGDPAWNFTLFDTLFERGWRFRSIPFVPPPAGGAAGGTPP
PGEPLAEGNRLTIMTVRKGVAIWVRSVEDEVPVEPMAGDTIIIMSPP

Sequences:

>Translated_607_residues
MQDNLAIGILCVLGGGIGAQWVAWRFRLPAIVLLFALGLLYGPGLNLLHPSAAIGGYFHPIVSLAVAFIVFEGGLGLDFR
QWRAAGEGVLRLTVVALPINWILGALAAHFVGHLHWGASWLFGAIIVVTGPTVVLPLLRHTKLRPRVAAFLRWEAILNDP
VGAILATLVLEFLMIQGNRHSGMFMAEIVPHLLFATMMALGCGVFPAVLVRFLSTRDLIPEILRIPIILTLAMSVFAVCN
FVMEGAGLMAATVFGMALTNMHVIGMSELRRIKESLGVLVVSCLFVMLTADLHRAVLERLSLPIVAMTLTVLFVVRPVGI
LLSTIRANLSWQERLFVGWIAPRGIVAAAVAGVAGLQLQEAGYPSADLVTPGVFALIATTMILHGFSLRPLARALRLTLS
DEPALAIVGASAWSTDLAGVLHRLGCPVMLVDTCTGALAPASRAGIPILKAELLSDEGLESLEERPADYLIAATPDAIYN
GLVCARLAPDFGRQRVFQVSPGVARLDLYRGLSRDSRGRVLGDPAWNFTLFDTLFERGWRFRSIPFVPPPAGGAAGGTPP
PGEPLAEGNRLTIMTVRKGVAIWVRSVEDEVPVEPMAGDTIIIMSPP
>Mature_607_residues
MQDNLAIGILCVLGGGIGAQWVAWRFRLPAIVLLFALGLLYGPGLNLLHPSAAIGGYFHPIVSLAVAFIVFEGGLGLDFR
QWRAAGEGVLRLTVVALPINWILGALAAHFVGHLHWGASWLFGAIIVVTGPTVVLPLLRHTKLRPRVAAFLRWEAILNDP
VGAILATLVLEFLMIQGNRHSGMFMAEIVPHLLFATMMALGCGVFPAVLVRFLSTRDLIPEILRIPIILTLAMSVFAVCN
FVMEGAGLMAATVFGMALTNMHVIGMSELRRIKESLGVLVVSCLFVMLTADLHRAVLERLSLPIVAMTLTVLFVVRPVGI
LLSTIRANLSWQERLFVGWIAPRGIVAAAVAGVAGLQLQEAGYPSADLVTPGVFALIATTMILHGFSLRPLARALRLTLS
DEPALAIVGASAWSTDLAGVLHRLGCPVMLVDTCTGALAPASRAGIPILKAELLSDEGLESLEERPADYLIAATPDAIYN
GLVCARLAPDFGRQRVFQVSPGVARLDLYRGLSRDSRGRVLGDPAWNFTLFDTLFERGWRFRSIPFVPPPAGGAAGGTPP
PGEPLAEGNRLTIMTVRKGVAIWVRSVEDEVPVEPMAGDTIIIMSPP

Specific function: This is probably a Na(+)/H(+) antiporter [H]

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Escherichia coli, GI87081854, Length=377, Percent_Identity=22.5464190981432, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 65081; Mature: 65081

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDNLAIGILCVLGGGIGAQWVAWRFRLPAIVLLFALGLLYGPGLNLLHPSAAIGGYFHP
CCCCCEEEEHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
IVSLAVAFIVFEGGLGLDFRQWRAAGEGVLRLTVVALPINWILGALAAHFVGHLHWGASW
HHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFGAIIVVTGPTVVLPLLRHTKLRPRVAAFLRWEAILNDPVGAILATLVLEFLMIQGNRH
HHHHHHEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
SGMFMAEIVPHLLFATMMALGCGVFPAVLVRFLSTRDLIPEILRIPIILTLAMSVFAVCN
CCEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVMEGAGLMAATVFGMALTNMHVIGMSELRRIKESLGVLVVSCLFVMLTADLHRAVLERL
HHHHCCHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLPIVAMTLTVLFVVRPVGILLSTIRANLSWQERLFVGWIAPRGIVAAAVAGVAGLQLQE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEEEECCHHHHHHHHHHHHCCEECC
AGYPSADLVTPGVFALIATTMILHGFSLRPLARALRLTLSDEPALAIVGASAWSTDLAGV
CCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHH
LHRLGCPVMLVDTCTGALAPASRAGIPILKAELLSDEGLESLEERPADYLIAATPDAIYN
HHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHCCCCEEEECCCHHHHH
GLVCARLAPDFGRQRVFQVSPGVARLDLYRGLSRDSRGRVLGDPAWNFTLFDTLFERGWR
CCHHHHHCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCEECCCCCCHHHHHHHHHCCCC
FRSIPFVPPPAGGAAGGTPPPGEPLAEGNRLTIMTVRKGVAIWVRSVEDEVPVEPMAGDT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCCCCE
IIIMSPP
EEEECCC
>Mature Secondary Structure
MQDNLAIGILCVLGGGIGAQWVAWRFRLPAIVLLFALGLLYGPGLNLLHPSAAIGGYFHP
CCCCCEEEEHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
IVSLAVAFIVFEGGLGLDFRQWRAAGEGVLRLTVVALPINWILGALAAHFVGHLHWGASW
HHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFGAIIVVTGPTVVLPLLRHTKLRPRVAAFLRWEAILNDPVGAILATLVLEFLMIQGNRH
HHHHHHEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
SGMFMAEIVPHLLFATMMALGCGVFPAVLVRFLSTRDLIPEILRIPIILTLAMSVFAVCN
CCEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVMEGAGLMAATVFGMALTNMHVIGMSELRRIKESLGVLVVSCLFVMLTADLHRAVLERL
HHHHCCHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLPIVAMTLTVLFVVRPVGILLSTIRANLSWQERLFVGWIAPRGIVAAAVAGVAGLQLQE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEEEECCHHHHHHHHHHHHCCEECC
AGYPSADLVTPGVFALIATTMILHGFSLRPLARALRLTLSDEPALAIVGASAWSTDLAGV
CCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHH
LHRLGCPVMLVDTCTGALAPASRAGIPILKAELLSDEGLESLEERPADYLIAATPDAIYN
HHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHCCCCEEEECCCHHHHH
GLVCARLAPDFGRQRVFQVSPGVARLDLYRGLSRDSRGRVLGDPAWNFTLFDTLFERGWR
CCHHHHHCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCEECCCCCCHHHHHHHHHCCCC
FRSIPFVPPPAGGAAGGTPPPGEPLAEGNRLTIMTVRKGVAIWVRSVEDEVPVEPMAGDT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCCCCE
IIIMSPP
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]